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FanDuel MLB DFS Lineup Picks (5/21/19): Daily Fantasy Baseball Advice

Austyn Varney highlights the top FanDuel MLB DFS lineup picks for 5/21/19, and a couple of sleepers to consider while building daily rosters.

Tonight's main slate starts at 7:05pm eastern and covers 14 games. There's also an all day slate starting at 6:05pm eastern that includes one extra early game.

In this article, I will be providing you with my daily fantasy baseball lineup picks for FanDuel on 5/21/2019. These picks will range from some of the elite players to mid-priced options and value plays.

We also provide DFS lineup picks for DraftKings and other sports. If you have any questions or comments, feel free to contact me on Twitter @varneydfs.

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FanDuel DFS Pitchers

SP - Justin Verlander, HOU vs CHW ($12,000)

We have a ton of pitchers to look at on this slate, but Verlander certainly stands out. The White Sox are bad against righties, striking out 26% of the time and making up for it with a measly .315 team wOBA. Verlander is a top 5 arm in baseball and he hasn’t slowed this year. He’s still striking out 10+ batters per nine innings and has held both righties and lefties to a sub .250 wOBA. The Astros are the biggest favorites of the night and it’s not close. Verlander is a no-brainer cash game option and the top play overall. 

SP - Spencer Turnbull, DET vs MIA ($8,600)

If you’re wanting to save some funds at pitcher, Spencer Turnbull and the Tigers are facing off with the worst lineup in baseball. The Marlins not only rank 30th against righties (wOBA), but it’s by a huge margin. They’re one of the worst hitting teams in the least twenty seasons and we should be targeting them as often as possible. Turnbull is certainly volatile, but he strikes out 11+ righties per nine, so should be fine at his price even if he gives up a run or three. Caleb Smith May dominate the Tigers as well and this could be a low-scoring affair, but I think Turnbull holds his own. If you’re looking for safety, Caleb Smith will give you that for an extra 2k. 

 

FanDuel DFS Infielders

1B - Dan Vogelbach, SEA at TEX ($3,800)

Vogelbach is still affordable and there’s really no excuse for it. He has 13 homers on the season and is sporting a .443 wOBA against righties. The Mariners go into Arlington and face off with Lance Lynn, who holds a 4.75 xFIP against lefties and has a big HR problem. Arlington is a huge upgrade from Seattle for power and Vogelbach will look to add number 14 to the books tonight. He’s affordable and has as much HR upside as anyone. 

2B - Wilmer Flores, ARI at SD ($2,700)

Matt Strahm is not a bad pitcher by any means,  but his 4.16 xFIP is telling us that he’s been lucky so far. Wilmer Flores is a monster against left-handers and will be hitting in the three hole at just $2,700. In what’s been his worst year of the last three, Flores is still sporting a .364 wOBA with two homers. The Diamondbacks offense is solid and you have to figure Flores gets involved. At the incredible cheap price tag, I don’t see a batter way to go at a weaker position in second base. 

3B - Miguel Sano, MIN at LAA ($3,300)

Since coming back just five games ago, Miguel Sano has hit 2 home runs and is seeing the ball nicely. He’s going to fit in quite well with a lineup that’s really just missing a power bat. Sano and the Twins face off with Trevor Cahill, who’s probably the worst pitcher on the entire slate. He’s not only allowed a .341 combined wOBA, but 6 ER+ in two of his last three. The Twins beat Cahill up just four days ago and the Angels will send him back out to the wolves. Sano is the top play at third base and it’s not close when you see the price.

SS - Gleyber Torres, NYY at BAL ($3,600)

Torres is swinging the hottest bat on the Yankees, hitting safely 16 times in the last nine games. Gleyber has stepped it up for an injured Yankees team that needs the line drives and hard contact.  We haven’t touched on the Yankees yet, but they’re firmly in play with David Hess on the mound and the Orioles bullpen backing him up. Torres will have a couple RBI opportunities throughout and I have a sneaky suspicion that he won’t disappoint.

 

FanDuel DFS Outfielders

OF - Christian Yelich, MIL vs CIN ($4,700)

Moving onto the outfield, Christian Yelich will be our expensive bat. He seems to either hit a home run or get 3 hits against everyone, and it really just comes down to limiting damage. Sonny Gray has struggled mightily against lefties, holding a .347 wOBA since ‘18. Yelich on the other hand, has posted a .435 wOBA against right-handers. Pure domination. If you can afford him while still loving the rest of your lineup, there’s no better place to go.

OF - Eddie Rosario, MIN at LAA ($4,200)

If you need to save a couple hundred, Eddie Rosario is my choice. He’s a guy who will be in every lineup of mine, as I think he clobbers Trevor Cahill. Cahill can’t strike anyone out and has trouble finding a put away pitch. As for Rosario, he’s u stoppable when putting the ball in play. He drives it for power and often has ducks on the pond. The Twins are our favorite offense of the night and Rosario is their best outfielder. Kepler and Cave are in play too if they find the lineup. 

OF - Kyle Schwarber, PHI vs CHI ($2,700)

If you want to save some funds, Kyle Schwarber should be hitting leadoff for the Cubs against Zach Eflin. Eflin, who struggles against lefties, (.354 wOBA) should struggle with this potent Cubs lineup. Schwarber gives you great exposure for cheap and at a position where you’re not missing out on anything. He not only has individual HR upside, but also has rally upside if the Cubs get going as a squad. The Phillies bullpen is good, but got worn out yesterday and may have some holes in it. Schwarber is a great discounted piece and deserves consideration in cash games and tournaments.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Jordan Westburg

to Have Season-Ending Elbow Surgery
Kendre Miller

Quickly Fading From Fantasy Relevance
Keon Coleman

Is Keon Coleman a Hopeless Dynasty Asset?
Marvin Harrison Jr.

a Buy-Low Candidate in Dynasty Formats
Hollywood Brown

a Cut Candidate in Dynasty Leagues?
Darnell Mooney

Barely Inside Top-100 WR Dynasty Rankings
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Christian Kirk

Can Christian Kirk Revive his Career in Bay Area?
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
Brashard Smith

Destined to Become Special Teams Player?
MMA

Dohoo Choi Returns At UFC Vegas 117
Ben Sinnott

Dynasty Value Hindered by Free-Agent TE Addition
Juan Diaz

Set To Make His UFC Debut
Sam Darnold

Should Dynasty Managers Continue to Hold Sam Darnold?
Malcolm Wellmaker

Looks To Bounce Back
Justin Fields

Dynasty Managers Getting Ready to Sell High on Justin Fields?
Christian Edwards

Set For His UFC Debut
Dallas Goedert

a Target for Dynasty Managers in Championship Window?
Modestas Bukauskas

Looks To Get Back In The Win Column
Theo Johnson

Not the Primary Option in New System?
Kyle Monangai

Still Time to Buy Low on Kyle Monangai in Dynasty Leagues?
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Amon-Ra St. Brown

an Unheralded Dynasty Cornerstone
Jerry Jeudy

Becoming an Undervalued Dynasty Depth Piece
Karl-Anthony Towns

Making an Impact as Playmaker in Playoffs
Skyler Bell

Could See Multiple Paths to Dynasty Relevance
Jalen Duren

Determined to Improve
Jayden Daniels

Still Worth Paying Up for in Dynasty Leagues
Kevin Huerter

Tagged as Questionable for Game 6 Against Cavaliers
Andrei Iosivas

' Already Low Standalone Value Sinks Lower
Caris LeVert

Considered Questionable for Friday
Duncan Robinson

Iffy for Game 6
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Tyjae Spears

has Limited Long-Term Upside in Dynasty Formats
Jaylen Wright

a Buy-Low Candidate as a Handcuff?
Ollie Gordon II

Dynasty Value Takes a Hit After Teammate's Extension
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Paul Reed

Makes Big Impact Off the Bench Wednesday
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Jarrett Allen

Records Double-Double in Game 5 Win
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF