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FanDuel MLB DFS Lineup Picks (4/21/19): Daily Fantasy Baseball Advice

Troy Klauder highlights the top FanDuel MLB DFS lineup picks for 4/21/19, and a couple of sleepers to consider while building daily rosters.

Today's main slate starts at 1:05 pm eastern and covers nine games. There's also an all day slate starting at the same time, featuring a glorious 15 game slate.

In this article, I will be providing you with my daily fantasy baseball lineup picks for FanDuel on 4/21/2019. The lineup picks will range from some of the elite players to mid-priced options and value plays.

If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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FanDuel DFS Pitchers

James Paxton, NYY vs KC ($9,600)

Paxton was absolutely brilliant his last time out, throwing eight scoreless innings with twelve strikeouts against the Red Sox. He's now got a beastly 32.6% K-rate on the season and gets a very easy matchup in the Royals, who have just a .278 wOBA versus left-handed pitching this year. Paxton should be regarded as an ace, and this may be your last chance to get him at a discounted price.

Kyle Gibson, MIN at BAL ($6,100)

Gibson is the third-cheapest starter on FanDuel today because he's been downright awful this year. However, he's got serious upside in a matchup against the Orioles. Much of Baltimore's lineup simply isn't major league caliber, resulting in a .290 wOBA versus righties this season. It's worth noting that Gibson is coming off a year where he threw nearly 200 innings with a 3.62 ERA, so there's absolutely a chance for a bounce-back performance. Gibson is attractive in GPP contests, especially considering that he'll allow you to spend lots of salary on high-end hitters.

 

FanDuel DFS Infielders

Jose Abreu, CWS vs DET ($2,900)

Abreu is off to a rough start, but there's no reason to worry about a 19 game sample. He obliterated lefties last year with a 144 wRC+ and should have a big day against Tigers southpaw Daniel Norris. Norris has pitched poorly in 8 1/3 innings this season, with just four strikeouts and three walks, as well as three homers allowed. Abreu is a fantastic value at his price.

Robinson Cano, NYM at STL ($3,400)

Cano is another slow starter whose price we can take advantage of. He is in a great spot batting third for the Mets, where he will see lots of run and RBI opportunities against Dakota Hudson. Hudson has been chewed up by opposing lineups and has a 6.08 ERA, so Cano can certainly be used as part of a Mets stack.

Corey Seager, LAD at MIL ($3,400)

Seager is an exciting play in Miller Park, an extreme hitter's environment where the Dodgers can score lots of runs. Regardless of whether he's batting second or third in the Dodgers order, Seager will be in a position to produce at a low price.

Alex Bregman, HOU at TEX ($4,000)

Bregman is an elite fantasy commodity who has picked up right where he left off last year, entering Sunday with a .916 OPS. He is in line for a enormous game against Shelby Miller, who has had a catastrophic 2019 campaign consisting of 11 walks in 10 innings with a 9.00 ERA.

 

FanDuel DFS Outfielders

Mookie Betts, BOS at TB ($3,900)

It was just last year that Betts was fantasy baseball's top performer, and we're already seeing him below $4,000? It's only April! Slow start or not, tough matchup or not - Betts needs to be in your lineups at this price.

Nelson Cruz, MIN at BAL ($3,400)

While his teammate Eddie Rosario took the spotlight yesterday, Nelson Cruz had a monster day of his own with two home runs. Cruz will be at it again from the cleanup spot against Dylan Bundy, who is one of the most homer-prone pitchers in all of baseball. Cruz continues to be undervalued, as he's rocking an elite 179 wRC+.

Ian Desmond, COL vs PHI ($2,900)

Don't you wish you could get some high-scoring Coors Field action in your lineups without wasting away all of your payroll? In that case, Ian Desmond is the bat for you. Yes, Desmond does suck, but it doesn't take much to rack up fantasy points in Colorado.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Bucky Irving

Potentially Undervalued After Disappointing Sophomore Season
Austin Reaves

Nears Double-Double In Game 3 Loss
Davante Adams

a Dynasty Hold Who Could See His Value Slip
LeBron James

Facing Sweep With Game 4 on Monday
Emeka Egbuka

The Pendulum Swinging Back on Emeka Egbuka's Dynasty Value
Ajay Mitchell

Posts Career Playoff Night in Game 3
Chet Holmgren

Helps Thunder Move to Brink of Conference Finals
Michael Pittman Jr.

Undervalued in an Environment Fit for His Skill Set
Tobias Harris

Extends 20-Point Streak in Saturday's Loss
Evan Mobley

Keeps Defensive Production Rolling Saturday
Rhamondre Stevenson

a Quality Dynasty Target in a Still-Improving Offense
Golden State Warriors

Warriors Extend Steve Kerr into his 13th Season
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Odell Beckham Jr.

Giants Not Looking to Sign Odell Beckham Jr. Right Now
Bo Nix

Will be Full Speed Before Training Camp
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Joey Logano

Needs a Good Run at Watkins Glen
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Duncan Robinson

Shines on Both Ends Saturday
Cade Cunningham

Records Second Career Postseason Triple-Double
Donovan Mitchell

Logs 35-Point Double-Double
James Harden

Plays Late Hero Saturday
OG Anunoby

Could Miss Another Game Sunday
Joel Embiid

Considered Probable for Sunday's Elimination Game
Jarred Vanderbilt

Active on Saturday Night
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
CHI

Blackhawks Bring in Roman Kantserov for Next Season
Mason McTavish

Set to Rejoin Ducks Lineup Sunday
Lukas Dostal

to Remain in Ducks Crease Sunday
Zach Bogosian

Back for Wild Saturday
Jesper Wallstedt

Starting Game 3 Against Avalanche
Joel Eriksson Ek

Not Ready to Return Saturday
Owen Tippett

Won't Play Saturday
Cooper Kupp

a Dynasty Hold into the Start of 2026 Season
Jaylen Warren

a Safe Dynasty Depth Piece with Insurance Upside
Christian McCaffrey

a Risky Dynasty Hold Who Still Exceeds His Trade Value
Brian Thomas Jr.

A Risky Buy-Low with Immense Upside
Tre' Harris

a Dynasty Hold That Could Require Patience
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Braelon Allen

Dynasty Stock Takes a Hit After Teammate's Extension
Josh Allen

Still the Top Dynasty QB in his Prime
Kyler Murray

Suddenly a Rising Dynasty Target in Minnesota
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Ronald Acuña Jr.

Ronald Acuna Jr. Optimistic About Returning Next Wednesday
Mike Matheson

Leads by Example in Game 2 Win
Jakub Dobes

Rebounds After Loss Yet Again for Montreal
Rachaad White

Undervalued in Dynasty Leagues Despite a Path to Upside
Alex Newhook

Sets Tone in Big Montreal Victory
Stephon Castle

Overcomes Shooting Struggles Friday
Jake Tonges

Should by Now Be Rostered by Every Kittle Dynasty Manager
Anthony Edwards

Carries Heavy Usage in Defeat
Chig Okonkwo

a Clear Breakout Candidate in Washington
Lukas Dostal

Gets Pulled in Game 3 Loss on Friday
Victor Wembanyama

Joins Historic Playoff Company
Mikal Bridges

Continues Postseason Surge with 23-Point Game
Aaron Jones Sr.

Still a Low-Cost, Short-Term Dynasty Target
Kelly Oubre Jr.

Keeps Scoring Role Alive
Romeo Doubs

' Buy Window Could Soon Be Wide Open
Joel Embiid

Held to 18 Points in 76ers Game 3 Loss
Brett Howden

Notches Sixth Goal of the Postseason
Jalen Brunson

Tallies 33 Points to Take 3-0 Series Lead
VEG

Mitch Marner Hat Trick Helps Vegas Take Series Lead
Pat Bryant

Working With Training Staff This Offseason
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Mats Zuccarello

Expected to Play Saturday
Joel Eriksson Ek

to Be a Game-Time Decision Saturday
Jonas Brodin

Still Out Saturday
Josh Manson

Could Return Saturday
Kaedan Korczak

Scratched for Game 3 Against Ducks
Radko Gudas

Likely to Remain Out Friday
Sam Carrick

Won't Play Friday
Blake Snell

to Make Season Debut for Dodgers on Saturday
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
Dan Vladar

Looks to Return to Winning Ways Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Framber Valdez

Suspended Six Games
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF