November 23, 2025
Cincinnati Bengals running back
Tahj Brooks (head) exited during the third quarter of Sunday's Week 12 contest against the New England Patriots to be evaluated for a concussion. According to an announcement from the team, he is officially listed as questionable to return. It's possible that he suffered the injury while returning the Patriots' kick at the start of the second half. At the time of his departure, Brooks had five rushing yards on two carries, as well as one uncaught target. On special teams, his lone return went for 20 yards. With
Samaje Perine (ankle) sidelined,
Gary Brightwell will take over as the No. 2 running back behind
Chase Brown until Brooks can return.
--Andersen PickardSource: Cincinnati Bengals
November 23, 2025
New Orleans Saints running back
Alvin Kamara (ankle) is officially active for Sunday's Week 12 contest against the Atlanta Falcons. He had been listed as questionable after practicing in a limited capacity. After a quiet stretch near the middle of the season, Kamara bounced back with a huge impact in his most recent game, tallying 83 rushing yards on 22 carries, plus an additional three catches for 32 receiving yards. We're still seeing flashes of Kamara being a versatile threat out of the backfield, operating as both a talented pure rusher and a valuable checkdown or short outlet for rookie quarterback
Tyler Shough. Coming off his bye, Kamara ranks as a fringe top-24 fantasy running back against Atlanta, especially in PPR leagues. We could see him occasionally be spelled by rookie
Devin Neal, who had seven touches on a 35% snap share in his last game. Still, Kamara remains the undisputed primary running back in New Orleans.
--Andersen PickardSource: Katherine Terrell
November 23, 2025
Jacksonville Jaguars tight end
Brenton Strange (hip) is officially active for his team's Week 12 matchup against the Arizona Cardinals. Strange has been on Injured Reserve since Week 5 due to a hip injury. Across five games before getting hurt, the 24-year-old recorded 20 catches for 204 yards on 24 targets. With wide receivers
Travis Hunter (knee) on Injured Reserve and
Brian Thomas Jr. (ankle) sidelined in Week 12 by an ankle injury, Strange has a chance to emerge as one of the lead pass-catching options for Jaguars quarterback
Trevor Lawrence. Still, Jacksonville could choose to bring him along slowly in his first game back from injury against the Cardinals. Fantasy managers may want to proceed with caution with Strange in Week 12, but he's a name to monitor on the waiver wire for the stretch run of the fantasy season.
--Will BradySource: Jacksonville Jaguars
November 23, 2025
Kansas City Chiefs right guard Trey Smith (ankle) has been ruled out for the remainder of his team's Week 12 matchup against the Indianapolis Colts due to an ankle injury. The 26-year-old entered the week graded by Pro Football Focus as the 11th-best guard in the NFL out of 80 qualified players, so his absence is a significant blow for the Kansas City offense. Without him, Jaylon Moore will likely take over at right guard for the remainder of Week 12. The exact severity of Smith's injury is unclear, but it's not a great sign that he is unable to return against Indianapolis. An extended absence for Smith could be problematic for Chiefs quarterback
Patrick Mahomes and the rest of the team's skill position players going forward.
--Will BradySource: Kansas City Chiefs
November 23, 2025
Green Bay Packers cornerback Keisean Nixon (stinger) has been ruled out for the remainder of his team's Week 12 matchup against the Minnesota Vikings due to a stinger. The 28-year-old recorded two solo tackles before being forced to exit the game. Losing Nixon is another blow for a Packers secondary that came into the game already without cornerback Nate Hobbs (knee). Without Nixon, Kamal Hadden, and possibly even converted wide receiver Bo Melton, will likely be forced into action at cornerback for Green Bay. Injuries in the Packers' secondary may be just what Vikings wide receivers
Justin Jefferson and
Jordan Addison need to get going in Week 12.
--Will BradySource: Green Bay Packers
November 23, 2025
Seattle Seahawks running back
George Holani (hamstring) has been ruled out for the remainder of his team's Week 12 matchup against the Tennessee Titans due to a hamstring injury. The 25-year-old did not record a carry or earn a target before exiting the game. Holani plays the RB3 role in Seattle behind
Kenneth Walker III and
Zach Charbonnet. Without Holani, Walker III and Charbonnet will now handle all of the Seahawks' backfield work for the remainder of Week 12. More information on the severity of Holani's injury should come following the game.
--Will BradySource: ESPN - Brady Henderson
November 23, 2025
Pittsburgh Steelers wide receiver
D.K. Metcalf (ankle) has returned to his team's Week 12 matchup against the Chicago Bears after briefly exiting the game due to an ankle injury. Metcalf limped off the field and was checked out in the medical tent, but was ultimately cleared to return to the field. Metcalf may not be at 100% for the remainder of Week 12, but Steelers fans and fantasy managers can breathe a sigh of relief that he avoided a major injury. Now that he's back in the lineup, the 27-year-old should continue to be the top target for Steelers backup quarterback
Mason Rudolph in Week 12 against Chicago. Metcalf scored a touchdown in the first half before tweaking his ankle.
--Will BradySource: The Athletic - Mike DeFabo
November 23, 2025
The Pittsburgh Steelers said that wide receiver
D.K. Metcalf (ankle) is questionable to return to Sunday's game against the Chicago Bears due to an ankle injury. The first-year Steeler limped off the field during the second quarter and is now up in the air to come back. Unfortunately for fantasy managers, Metcalf looked to be breaking his recent slump before the injury. At the time of Metcalf's exit, he had caught two of three targets for nine yards and also rushed twice for 12 yards and a touchdown. Pittsburgh leans heavily on tight ends and running backs in the passing game, but will turn to receivers
Calvin Austin III and
Ben Skowronek if Metcalf can't return.
--Nick PiotrowiczSource: Pittsburgh Steelers
November 23, 2025
The Atlanta Falcons could opt to be cautious with wide receiver
Drake London (knee) in the weeks to come, according to Tom Pelissero of NFL Network. The former USC star is dealing with a PCL injury, which Falcons head coach Raheem Morris said would keep London on a week-to-week basis. If the Falcons lose to New Orleans on Sunday, however, Pelissero noted that Atlanta will be all but eliminated from making the playoffs, which could cause the team to take London's return very slowly. Atlanta's odds are already low as they turn to backup quarterback
Kirk Cousins, who is replacing starter
Michael Penix Jr. (knee) following a season-ending injury. Fantasy managers who roster London may have to devise a Plan B if the receiver is going to be absent in the coming weeks.
--Nick PiotrowiczSource: NFL Network
November 23, 2025
Green Bay Packers quarterback
Jordan Love (shoulder) is playing through a sprained AC joint injury, according to Ian Rapoport of NFL Network. Luckily for Love and the Packers, the injury is to his left (non-throwing) shoulder. Had the injury been to Love's right shoulder, Rapoport noted that the quarterback would not have been able to play, but he was able to practice fully this week and is active in Week 12 versus the division-rival Minnesota Vikings. Nonetheless, the injury isn't exactly pleasant, so it will be worth watching to see how Love performs. Fantasy managers counting on Love should keep an eye on how he plays through the pain against Minnesota.
--Nick PiotrowiczSource: NFL Network
November 23, 2025
Jacksonville Jaguars wide receiver
Brian Thomas Jr. (ankle) is missing a third straight game in Week 12 against the Arizona Cardinals due to a high-ankle sprain, but NFL Network's Tom Pelissero reports that Thomas is getting close and is likely to return next week to face the division-rival Tennessee Titans. The 23-year-old practiced in a limited fashion all week, but the Jags are playing it safe and will hold the former first-rounder out again this weekend in Arizona. It's been a disappointing sophomore season for Thomas after he impressed with an 87-1,282-10 line in 17 games in his rookie campaign in 2024. Thomas has just 30 catches for 420 yards and one touchdown in eight games in 2025, but he should return to a key role in the passing attack when he's healthy, with first-round rookie
Travis Hunter (knee) done for the year.
--Keith HernandezSource: NFL Network - Tom Pelissero
November 23, 2025
Detroit Lions right tackle Penei Sewell (ankle) is officially active for Sunday's Week 12 contest against the New York Giants. He had been listed as questionable after logging back-to-back limited practices. The 25-year-old will suit up for his 11th game of the 2025 season, providing key protection to
Jared Goff,
Jahmyr Gibbs, and
David Montgomery. Sewell has allowed zero sacks this season, so his presence is quite important as the Lions look to slow down a Giants pass rush headlined by Brian Burns, who has 13 sacks.
--Andersen PickardSource: Madelyn Burke
November 23, 2025
Minnesota Vikings edge rusher Jonathan Greenard (shoulder) is officially inactive for Sunday's Week 12 contest against the Green Bay Packers. He had been listed as questionable after logging a pair of limited practice sessions. The 28-year-old Florida product will ultimately miss his second consecutive game, leaving a large void within Minnesota's defensive front. After all, he had 31 tackles, two sacks, and one forced fumble through his first nine contests this year. Dallas Turner is expected to earn the start in Greenard's absence. Turner was a productive fill-in last week, amassing seven tackles and one sack.
--Andersen PickardSource: Tanner Weber
November 23, 2025
NFL Network's Ian Rapoport reports that the Baltimore Ravens will consider resting quarterback
Lamar Jackson every Wednesday to keep him fresh for the rest of the 2025 season. Jackson missed a few games earlier this year with a hamstring injury and has missed the last two Wednesday practices due to minor ankle and knee injuries. The 28-year-old figures to be a non-participant on Monday, too, but he should be just fine for the Thanksgiving Day game against the division-rival Cincinnati Bengals next Thursday (as long as he comes out of Week 12 without any injuries). Jackson hasn't looked the same on the ground this year, which has kept him from the elite tier of QB1 options in fantasy football. However, the two-time MVP is still a set-and-forget QB1 in fantasy football and could be primed for a bounce-back performance on Sunday against the visiting New York Jets.
--Keith HernandezSource: NFL Network - Ian Rapoport
November 23, 2025
Detroit Lions wide receiver
Isaac TeSlaa (oblique) is officially active for Sunday's Week 12 contest against the New York Giants. He had been listed as questionable after practicing in a limited capacity. The rookie has merely occupied a depth role in his first pro season, catching four of his eight targets for 65 yards and two touchdowns through 10 games. Not only has TeSlaa been operating behind standout receivers
Amon-Ra St. Brown and
Jameson Williams, but he's also been far less involved than
Kalif Raymond. As long as those three pass catchers remain healthy, TeSlaa can be avoided in fantasy football. He should be stashed in dynasty leagues and left on waivers in redraft formats.
--Andersen PickardSource: Tim Twentyman
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