November 16, 2025
San Francisco 49ers running back
Christian McCaffrey had 13 carries for 81 rushing yards and two rushing touchdowns during Sunday's Week 11 win over the Arizona Cardinals. He also caught five of his six targets for an additional 40 receiving yards and one receiving touchdown. The superstar running back continues to demonstrate excellence as a rusher and receiver, and his big game officially propelled him past
Jonathan Taylor for the overall RB1 spot (PPR) through 11 weeks. Given that he was a late-first-round pick in most redraft leagues this year, managers are getting even more than they expected from the 29-year-old. He remains a must-start RB1 for Week 12 against his old team, the Carolina Panthers.
--Andersen PickardSource: RotoBaller
November 16, 2025
Detroit Lions wide receiver
Isaac TeSlaa (oblique) is officially active for Week 11 against the Philadelphia Eagles on Sunday Night Football. He was listed as questionable after being a late addition to the injury report. The rookie has occupied a depth role in his first pro season, catching four of seven targets for 65 yards and two touchdowns through nine games. He remains off the redraft radar as long as
Amon-Ra St. Brown and
Jameson Williams are both healthy.
--Andersen PickardSource: Detroit Lions
November 16, 2025
Atlanta Falcons quarterback
Michael Penix Jr. (knee) aggravated the same knee injury that forced him to miss time earlier this season, according to Ian Rapoport of NFL Network. The second-year quarterback had completed 13 of his 16 pass attempts for 175 yards before exiting Sunday's Week 11 loss against the Carolina Panthers. Rapoport notes that Penix is headed for additional testing, but the initial expectation is that he will miss time. That would leave
Kirk Cousins in line to make his second start of the season next Sunday against the New Orleans Saints. The veteran went just 6-for-14 passing with 48 yards in relief of Penix this week. He led zero touchdown drives but did get Atlanta in position for two fourth-quarter field goals.
--Andersen PickardSource: Ian Rapoport
November 16, 2025
Cleveland Browns quarterback
Shedeur Sanders will return to the backup role if
Dillon Gabriel (concussion) clears concussion protocol ahead of Week 12 against the Las Vegas Raiders. Head coach Kevin Stefanski confirmed that Gabriel will be the starter when healthy. Gabriel exited midway through Sunday's Week 11 contest against the Baltimore Ravens. He had orchestrated a six-point lead, but Sanders struggled upon entering, completing just four of his 16 pass attempts with one interception and two sacks. Neither Gabriel nor Sanders is very appealing in redraft leagues, and both would rank outside the top 24 quarterbacks against Las Vegas.
--Andersen PickardSource: Daniel Oyefusi
November 16, 2025
Cleveland Browns quarterback
Dillon Gabriel (concussion) has entered the league's concussion protocol, leaving his status for Week 12 against the Las Vegas Raiders up in the air. However, according to head coach Kevin Stefanski, Gabriel will remain the starter if he is healthy and clears concussion protocol. The Oregon product was replaced by fellow rookie
Shedeur Sanders following his injury, but it didn't go very well as Sanders completed just four of his 16 pass attempts, took two sacks, and threw an interception. Gabriel, on the other hand, went 7-for-10 passing with 68 yards through the air, and he also led four scoring drives. Cleveland is at its best when it controls the rushing attack, which leaves Gabriel outside the top 24 fantasy quarterbacks going forward.
--Andersen PickardSource: Daniel Oyefusi
November 16, 2025
Buffalo Bills wide receiver
Tyrell Shavers caught four of his five targets for a team-high 90 yards and a touchdown during Sunday's Week 11 win over the Tampa Bay Buccaneers. His biggest play of the game was a 43-yard touchdown that temporarily gave Buffalo the lead in the second quarter. Shavers capitalized on an increased opportunity to produce with
Keon Coleman (coach's decision) inactive. The third-year receiver played 53.6% of the offensive snaps, setting a new career-high. Coleman should return to action next week, but Shavers has shown that he deserves to compete for more opportunities alongside Coleman,
Khalil Shakir, and
Joshua Palmer.
--Andersen PickardSource: RotoBaller
November 16, 2025
Jacksonville Jaguars running back
Travis Etienne Jr. had 19 carries, 73 rushing yards, and two rushing touchdowns during Sunday's Week 11 win over the Los Angeles Chargers. He was unable to haul in either of his two targets in the passing game. Etienne ceded early-game touches to
Bhayshul Tuten (ankle), but then the rookie left the game with an injury, clearing the way for Etienne to re-establish himself as the lead back. The 26-year-old took full advantage of the opportunity, helping fuel a 35-6 upset victory at home. If Tuten is healthy in Week 12, we could see somewhat of a 50/50 backfield split, as both running backs have proven that they are effective and can provide a spark. In a split backfield, Etienne is a low-end RB2. However, he would jump to the RB1 tier if he operates as the workhorse or if Tuten misses time.
--Andersen PickardSource: RotoBaller
November 16, 2025
Houston Texans wide receiver
Nico Collins caught nine of his 10 targets for 92 yards and a touchdown during Sunday's Week 11 win over the Tennessee Titans. Collins paced the team in all major receiving categories, building on an equally impressive performance from back in Week 10. The Texans' top receiver has strung together three impressive games in a row, amassing at least 10 targets, seven receptions, and 14.5 fantasy points (PPR) in each of those contests. He ranks as a top-24 fantasy receiver this season, but his latest hot streak has him teetering on the edge of the WR1 tier for a Week 12 contest against the Buffalo Bills that will likely require
C.J. Stroud (concussion) to throw a lot.
--Andersen PickardSource: RotoBaller
November 16, 2025
Pittsburgh Steelers running back
Kenneth Gainwell was a stud through the air during Sunday's game against the Cincinnati Bengals. Gainwell saw increased playing time with
Jaylen Warren (ankle) barely playing in the second half. The 26-year-old rushed the ball nine times and was held to 26 yards on the ground. However, Gainwell was excellent in the receiving game this weekend. He hauled in seven of his eight targets for 81 yards and scored two touchdowns in the win. Gainwell could see a larger workload if Warren is forced to miss time. Fantasy managers will need to check back for another update. Gainwell could be a popular waiver wire addition ahead of the Week 12 matchup against the Chicago Bears.
--Andy WebbSource: ESPN
November 16, 2025
San Francisco 49ers kicker
Eddy Pineiro (hamstring) is considered questionable to return to Sunday's game against the Arizona Cardinals. Pineiro appears to have pulled his hamstring during the second half of this contest. The assumption is that punter Thomas Morstead would take over as the kicker for the rest of the contest. The 49ers are already up multiple scores in the middle of the fourth quarter. That being said, San Francisco might elect to not kick at all. Before exiting, Pineiro knocked down all three field goal attempts, while connecting on 2-of-4 extra points kicks in this game. Fantasy managers will need to check back for another update on Pineiro.
--Andy WebbSource: Eric Branch
November 16, 2025
Atlanta Falcons running back
Bijan Robinson seemed unstoppable during Sunday's game against the Carolina Panthers. Robinson saw a heavy workload as he rushed the ball 23 times for 104 yards and scored two touchdowns in the overtime loss. Robinson scored a one-yard and a four-yard touchdown, so not flashy plays, but he got the job done. He also hauled in four of his five targets for an additional 39 yards through the air. Robinson had a few sluggish weeks, but he is back to giving fantasy managers elite value. He'll head into a plus-matchup against the New Orleans Saints in Week 12.
--Andy WebbSource: ESPN
November 16, 2025
Los Angeles Rams tight end
Tyler Higbee (ankle) is currently considered questionable to return to Sunday's game against the Seattle Seahawks. Higbee suffered an ankle injury during the second half of this contest. The severity of the issue is unclear, but it's already the fourth quarter, so it's uncertain if he'll return. Before exiting, Higbee hauled in one of his two targets for 23 yards.
Terrance Ferguson figures to move up the depth chart and take on a larger role for the rest of this game, assuming Higbee doesn't return.
--Andy WebbSource: Stu Jackson
November 16, 2025
Cleveland Browns quarterback
Dillon Gabriel (concussion) has been ruled out for the rest of Sunday's game against the Baltimore Ravens. Gabriel was pulled out and was taken to the locker room to be evaluated for a concussion. He didn't join the team in the second half and is officially done for the day. Before exiting, Gabriel completed 7-of-10 passing attempts for 68 yards. Now,
Shedeur Sanders will take over under center for the rest of this game. Sanders is making his NFL debut and gets a chance to prove himself with his team leading to begin the second half.
--Andy WebbSource: Mary Kay Cabot
November 16, 2025
Green Bay Packers running back
Josh Jacobs (knee) was forced to exit early during Sunday's game against the New York Giants. Jacobs was pulled out in the second quarter due to a knee issue and didn't return. He finished the game with seven carries for 40 yards in the victory. The organization is uncertain of the severity of the injury right now, but doesn't believe it's a season-ending injury. Jacobs is set to undergo further testing on Monday. If he misses time,
Emanuel Wilson and
Chris Brooks would stand to gain value. Fantasy managers will need to check back for another update on Monday.
UPDATE: Jacobs will have more tests on his left knee on Monday. He was able to briefly return after jamming his knee into the MetLife Stadium turf in Sunday's 27-20 win before leaving for good. There is optimism that Jacobs will be back soon.--Andy WebbSource: Adam Schefter
November 16, 2025
Carolina Panthers rookie wide receiver
Tetairoa McMillan caught eight of 12 targets for 130 yards and two touchdowns during Sunday's Week 11 win over the Atlanta Falcons in overtime. McMillan continues to showcase a phenomenal rapport with
Bryce Young, fetching at least eight targets in eight of his first 11 games. The rookie set new season-highs (and, thus, career-highs) in targets, catches, and receiving yards on Sunday. He'll look to build on his momentum as a high-end WR2 with WR1 upside entering Week 12 against the San Francisco 49ers.
--Andersen PickardSource: RotoBaller
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