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FanDuel MLB DFS Lineup Picks (9/21/19): Daily Fantasy Baseball Advice

Joel Bartilotta highlights the top FanDuel MLB DFS lineup picks for 9/21/19, and a couple of sleepers to consider while building daily rosters.

We have one week left in the regular seasom and it's amazing that it's come to a close so quickly. It's been a great year up to this point and we're going to keep the good plays rolling here and through the playoffs.

This time of the year does call for craziness and you need to keep an eye on lineups and pitch counts to avoid any wacky changes.

Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @Bartilottajoel

Black Friday Special! Save 50% on any Big-4 Sports Premium Pass using discount code THANKS. Win more with our DFS, Betting and Season-Long Premium Pass, get expert tools and advice for NBA, NFL, MLB, NHL from from proven winners! Dan Palyo leads the team with exclusive picks for DFS picks, Props, betting. Enhance your game with industry-leading tools like our Lineup Optimizers, Team Sync Platform, DFS Cheat Sheets and more. GAIN ACCESS

 

FanDuel DFS Pitchers

Jose Berrios, MIN vs. KC ($9,400) 

Berrios hasn’t quite been the same pitcher he was in the first half but it’s lowered his price to this enticing number. We’re still talking about a guy with a 3.58 ERA and 1.21 WHIP. Most importantly, he’s scored at least 35 FanDuel points in 15 outings this season while also throwing at least 6.2 innings in the same amount of starts. He appears to have captured that form recently, throwing at least seven innings in back-to-back starts while averaging 46.5 FanDuel points per game in that span. Facing a 28th-ranked Royals offense is the icing on the cake, with Berrios entering this matchup as a –320 favorite.

Ivan Nova, CWS at DET ($6,000) 

We always have to consider pitchers against the Tigers, particularly someone as hot as Nova. Let’s start with that matchup, as he faces a Detroit club who ranks dead-last in runs scored, OBP, OPS, wOBA, K rate and xwOBA. That’s scary against someone who’s really hitting their stride recently, with Nova pitching to a 3.12 ERA and 1.28 WHIP over his last 12 starts. That’s really all you can ask for from someone this cheap, especially in such a tasty matchup.

 

FanDuel DFS Infielders

Eric Thames – 1B, MIL vs. PIT ($2,800) 

Thames has been fantastic against right-handers throughout his career and it really doesn’t make sense why FanDuel is keeping his price below $3,000. Dating back to 2017, Thames has a .355 OBP, .523 SLG and .878 OPS with the platoon advantage in his favor. That’s all you can ask for from a player this cheap, particularly against a rookie with a 9.00 ERA.

Luis Arraez – 2B, MIN vs. KC ($2,600) 

This is yet another price that I can't understand. Arraez has done nothing but rake since getting called up, which is evident by his .346 AVG and .858 OPS. He’s actually been even better against righties, amassing a .415 OBP, .495 SLG and .910 OPS against them this season. We’re really not worried about Glenn Sparkman and his 6.02 ERA and 1.50 WHIP either.

Matt Chapman – 3B, OAK vs. TEX ($3,600) 

Chapman has been making minced meat of lefties all season long and this is yet another spot where we want to use him. For the year, Chapman has a .543 SLG and .883 OPS with the platoon advantage in his favor. This happens to be a weak lefty too, with the Rangers sending out Brock Burke and his 5.19 ERA and 1.31 WHIP.

Carlos Correa – SS, HOU vs. LAA ($3,800) 

Correa just hit two dingers on Friday night and it appears that he’s back to full health. This is a guy who absolutely destroys baseballs when he is healthy, generating a .279 AVG, .560 SLG and .918 OPS for the year. Those are brilliant numbers and we absolutely love his .934 OPS against lefties since the beginning of 2017. This is not a southpaw we’re concerned with either, with Pablo Sandoval pitching to a 4.91 ERA and 1.36 WHIP.

 

FanDuel DFS Outfielders

Kyle Schwarber, CHC vs. STL ($3,700) 

Schwarber has always been one of the most talented hitters in baseball and his recent form shows just how special he can be. Over his last 42 games played, Schwarber has a .354 OBP, .643 SLG and .997 OPS. That’s why he’s now in the heart of the Cubs order and he’s typically much better against right-handers. Dakota Hudson’s 4.99 FIP and 1.39 WHIP makes him a guy who’s due for some negative regression too.

Jordan Luplow, CLE vs. PHI ($2,700) 

Luplow has been killing left-handers all season long and it’s time for people to start taking notice of these absurd splits. Against southpaws, Luplow has a .322 AVG, .437 OBP, .729 SLG and 1.165 OPS. Those are literally Hall-of-Fame numbers and it’s a major reason why he typically bats cleanup in these circumstances. Jason Vargas is not a lefty we need to fear either, pitching to a 4.48 ERA and 1.34 WHIP.

MLB DFS News and Injury Alerts




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REAL-TIME FANTASY NEWS

Aaron Gordon

Won't Return to NBA Cup Meeting with Houston
Travis Kelce

Open to Returning in 2026?
Onyeka Okongwu

Could Miss Matchup With Pelicans
Brandon Aiyuk

49ers, Brandon Aiyuk Headed for a Divorce Soon?
D'Angelo Russell

Ruled Out Against Pelicans
Trey Hendrickson

Ruled Out for Week 12
Tre Jones

Cleared to Play Friday with Planned Minutes Limit
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Cleared to Face Phoenix
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Ruled Out for Friday's Game Against Miami
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Ruled Out on Friday
Jaren Jackson Jr.

Doubtful as Grizzlies Face Mavericks
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Rangers Non-Tender Adolis Garcia on Friday
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Returning Versus Indiana
Darius Garland

Cleared to Play on Friday, Expected to See Limited Action
Marvin Bagley III

to Miss Friday's Game Against Raptors
Auston Matthews

Doubtful for Saturday
Rashod Bateman

Ruled Out for Week 12
Alexandre Sarr

Ruled Out for a Second Straight Game
Roman Josi

Could Return Saturday
Samuel Honzek

Out for Six Months After Surgery
Chris Godwin

Officially Questionable for Week 12
Sion James

Expected to Play Through Groin Issue Saturday
Jalen Chatfield

Available for Friday's Matchup
Andrew Wiggins

Labeled as "Day-to-Day"
Nico Sturm

Activated From Injured Reserve
Jason Zucker

Available Friday
Brandon Miller

Returning To Charlotte's Lineup On Saturday
Connor Hellebuyck

to Miss 4-6 Weeks
Jaylen Warren

Cleared From Injury Report Ahead of Week 12
Jalen Brunson

Probable For Saturday's Matchup With The Magic
Brian Thomas Jr.

Ruled Out for Week 12
Kenneth Walker III

Listed as Questionable for Week 12
Kyle Filipowski

Good To Go Friday Night
Trey Benson

Ruled Out For Week 12
Shaedon Sharpe

Won't Suit Up Friday
Jrue Holiday

to Miss Fourth Straight Game Friday Night
Josh Jacobs

Officially Questionable to Play in Week 12
Darius Slayton

Cleared to Return From Hamstring Injury in Week 12
Daniel Jones

"Good to Go" for Week 12
Alvin Kamara

Officially Questionable to Play in Week 12
Xavier Worthy

"Trending in the Right Direction," Officially Questionable
Isiah Pacheco

Out Against Colts
Drake London

Officially Ruled Out for Week 12
CFB

Beau Pribula Expected to Start Against Oklahoma
Aaron Rodgers

Questionable to Play Against Bears
Grayson Allen

Sidelined Again on Friday
Jaden McDaniels

Could Miss Another Game on Friday
Rhamondre Stevenson

Expected to Return in Week 12
Jayden Reed

Packers Open Jayden Reed's Practice Window on Friday
Chris Godwin

Trending Toward Playing on Sunday
Joe Burrow

Officially Questionable for Week 12
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
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A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
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Looks To Win Back-To-Back Fights
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Makes His Welterweight Debut
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Leads Blue Jackets to Victory in Toronto
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Posts Second Shutout of the Season
Alex Ovechkin

Nets 33rd Career Hat Trick
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Ruled Out for Friday
Gavin Brindley

Hurt Versus Rangers
Jake Evans

Exits With Injury Thursday
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
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Ready for Action Thursday
Lars Eller

Available Thursday
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Out Against Ducks
Jake Neighbours

Back for Blues Thursday
TB

Nicholas Paul Available Thursday
Victor Hedman

Out for "Couple of Weeks"
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Set to Return Thursday
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Returning to the Braves on One-Year Deal
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Looking to Continue Fall Run at RSM Classic
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Looking to Bounce Back at RSM Classic
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Searching for Turnaround at RSM Classic
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Searching for Momentum at RSM Classic
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Trying to Find Form at the RSM Classic
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Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
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Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer
CFB

Sam Leavitt Set to Enter Transfer Portal?
Jose Altuve

Undergoes Foot Surgery
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
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James Franklin to be Virginia Tech's Next Head Coach
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Beau Pribula Has Chance to Face Oklahoma on Saturday
Jack Della Maddalena

Gets Dominated
Islam Makhachev

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Gets Outclassed
Valentina Shevchenko

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Sean Brady

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Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries

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