👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

Midwest Region Picks: March Madness Bracket Predictions

NCAA Tournament bracket picks and team predictions for the Midwest Region. Read Seth's March Madness picks, sleepers and busts including teams to target and avoid.

March Madness is officially here, so let's fill out some winning brackets! RotoBaller will be bringing you a full breakdown on each tournament region, including some potential sleepers and busts. Today we'll be taking a look at the Midwest Region and my bracket picks.

I'm here to tell you some teams that I believe in to help you make the right tournament bracket decisions. Below I analyze the top four seeds, a potential bust, and a potential final four candidate. Hopefully my college basketball predictions can help you win your March Madness brackets. Now let's get to it.

Editor's Note: Be sure to check out the rest of our NCAA Tournament articles and analysis, including a guide on how to fill out your brackets. Read our March Madness picks, sleepers, busts and predictions for the East, South, and West regions.

 

Midwest Region Top Four Seeds 

Top four seeds: No. 1 North Carolina, No. 2 Kentucky, No. 3 Houston, No. 4 Kansas

Carolina is the final one seed and some think Michigan State should've gotten that nod. Nevertheless, here we are and Carolina greatly benefits with a seemingly clear path to the Elite Eight. They are led by freshman-phenom point guard Coby White and senior big man Luke Maye. They are a well-rounded team.

Kentucky has lost three times since February (twice to Tennessee and once to LSU). When both Reid Travis and P.J. Washington are healthy, they are tough to beat. They are a bruising physical bunch. Their loss to Tennessee in the SEC semis may be the best thing to happen to them.

The odds are stacked against Houston. Top-three seeds unranked before the season have made the Final Four just two times out of 53 since the field expanded in 1986. Houston falls under that category. They have only lost three times all season and they could very well make the Elite Eight, but I'd be hesitant to put them in the Final Four.

Watching Kansas on the road and at home is like watching two different teams. They were 17-0 at home this season and 3-8 on the road. Now you may be wondering, why I'm talking about home and road stats when the NCAA Tournament is played only at neutral-sites. Well, the committee placed Kansas in the Midwest region and the Sweet 16 and Elite Eight are in Kansas City, MO. So if Kansas can get through the first weekend in Salt Lake City, UT, they'll have a major home-court advantage for the Sweet 16 and Elite Eight.

 

Most Intriguing First-Round Matchup: No. 7 Wofford vs. No. 10 Seton Hall

The Southern conference champs are on a 20-game winning streak without a single loss in their conference. They also are second in the nation in team three-point percentage. Ken Pomeroy even has them as the 19th-rated team. But they are running into a well-coached, gritty, and scrappy Seton Hall squad.

The Pirates have a great scorer in Myles Powell and the big bodies down low to hang with anyone. They may get behind in the first half, but I've seen them battle back far too often to ever count them out. I think the fact that Seton Hall has played in more close, grind-it-out games in bigger moments, will be the deciding factor against Wofford.

 

Bust of the Region

Kansas. I don't think they're getting out of the first weekend so they won't have the chance to play with a massive home-court advantage. They're an underwhelming team that is not your typical Kansas team.

 

Final Four Pick

Kentucky. The Wildcats are really good and losing in the SEC semifinals is probably the best thing that happened to them. They'd face Wofford/Seton Hall in the second round and while both teams are good, Kentucky will be too much. In the Sweet 16, Houston or Iowa State don't have the bodies to hang with Kentucky. In the Elite Eight, they'd most probably face North Carolina and at that point, it comes down to the last possession.

More March Madness Brackets Advice




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
Terry McLaurin

the Undisputed Focal Point of Washington's Offense
Justin Herbert

a Dynasty Target with New-Look Offense Around Him?
Tee Higgins

an Intriguing Dynasty Trade Target with QB Healthy?
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Morgan Geekie

Collects Second Career Hat Trick
Joel Eriksson Ek

has Three Points in Victory
Jacob deGrom

Doesn't Have Structural Damage in his Knee
J.T. Realmuto

Leaves Game on Tuesday Due to Bruised Right Foot
Shaedon Sharpe

Picks Up Doubtful Tag
New York Giants

Dexter Lawrence Looking for $30 Million Annually?
Stephon Castle

Considered Doubtful for Wednesday
Marte Mapu

Texans Acquire Linebacker Marte Mapu From Patriots
Jaxson Hayes

a Late Scratch Against Thunder
Cleveland Browns

Browns Considering Francis Mauigoa at No. 6 Overall?
Max Strus

Returning to Action Wednesday
Deshaun Watson

Medically Cleared for QB Competition
Caleb Martin

Still Sidelined Tuesday
Donovan Mitchell

Listed as Questionable for Wednesday
James Conner

Present for Start of Offseason Program
James Harden

Available Wednesday
Brandon Williams

Ruled Out Tuesday
Cam Skattebo

in Attendance at Offseason Program
Malik Nabers

to be Ready to Play at Some Point in Training Camp
Kevin Porter Jr.

Undergoes Season-Ending Surgery
P.J. Washington

Out Tuesday Against Clippers
Marvin Bagley III

Daniel Gafford Out, Marvin Bagley III Available Tuesday
Kristaps Porzingis

Ruled Out Tuesday
Stephen Curry

Good to Go Tuesday
Duncan Robinson

Available Wednesday
Tobias Harris

Set to Return Wednesday
Victor Wembanyama

MRI is Clean, but he's Doubtful Wednesday
Cade Cunningham

Questionable Wednesday
Cody Ponce

to Have Knee Surgery, Expected to Miss Six Months
Coby White

Ruled Out Tuesday
Kyle Filipowski

Good to Go Tuesday
Ace Bailey

Ruled Out Against Pelicans
Sandro Mamukelashvili

Active Against Heat
Alejandro Kirk

Facing Six-Week Absence
Jacob deGrom

to Undergo MRI on Tuesday
Mike Trout

Back in the Lineup on Tuesday
Hunter Brown

Diagnosed with Grade 2 Shoulder Strain
Pavel Mintyukov

Returns From Three-Game Absence
Cutter Gauthier

Remains Sidelined Tuesday
Kirby Dach

Ready to Return Tuesday
Jordan Staal

Good to Go Tuesday
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Valeri Nichushkin

Nicolas Roy Available Tuesday
Cale Makar

Expected to Miss More Time
Matthew Tkachuk

Sits Out Tuesday's Game
Cade Horton

to Undergo Season-Ending Elbow Surgery
De'Von Achane

Not Present for Start of Voluntary Workouts
Malik Nabers

Present for Start of Offseason Program
NFL

Fernando Mendoza Not Planning to Attend the NFL Draft
New York Giants

Dexter Lawrence to Get a New Deal From Giants?
Carolina Panthers

Diego Pavia Visiting With Panthers on Tuesday
Pittsburgh Steelers

Steelers Hosting Denzel Boston on Pre-Draft Visit on Tuesday
Malik Willis

Dolphins Looking to Build Around Malik Willis
Kyle Pitts Sr.

Signs Franchise Tag, Present for Offseason Workouts
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Evan Engram

Fading Value Could Sink Even Lower After NFL Draft
TreVeyon Henderson

Experience and Emphasis on Run Game Could Help TreVeyon Henderson's Value Soar
Caleb Williams

The Sky is the Limit for Caleb Williams in Second Season with Ben Johnson
Nikita Kucherov

Nets 400th Career Goal
Evander Kane

Unlikely to Play Tuesday
Kevin Lankinen

Won't Dress on Tuesday
Morgan Barron

Considered Week-to-Week
Pontus Holmberg

Suffers Upper-Body Injury Monday
Philipp Grubauer

Exits With Injury Monday
Mark Scheifele

Collects Three Helpers on Monday
Jacob deGrom

Pitches Through Knee Issue on Monday
Ukko-Pekka Luukkonen

Defeats the Lightning
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Andrew Mangiapane

Available for Monday's Tilt
Shane Wright

Expected to Miss Another Game
Vladislav Namestnikov

Available Monday
Anthony Cirelli

Out Against Sabres
Mike Trout

Held Out of Series Opener Against Braves
Alejandro Kirk

to Undergo Thumb Surgery on Tuesday
Juan Soto

Mets Place Juan Soto on 10-Day Injured List
Matthew Boyd

Cubs Putting Matthew Boyd on 15-Day Injured List With Biceps Strain
Mickey Moniak

Goes Yard Twice Against his Old Team
Brent Rooker

Homers Twice, Drives in Six in Win Over Astros
Mike Trout

Considered Day-to-Day With Hand Contusion
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
Mike Trout

Exits Early After Getting Hit by Pitch
Pete Fairbanks

Serving as Opener Before Going on Paternity List
George Klassen

Called Up to Start on Sunday
Chris Duncan

Set For UFC Vegas 115 Main Event
Renato Moicano

An Underdog At UFC Vegas 115
Tabatha Ricci

Set For UFC Vegas 115 Co-Main Event
Virna Jandiroba

Looks To Bounce Back
Brendson Ribeiro

In Desperate Need Of Win
Abdul-Rakhman Yakhyaev

Looks To Remain Unbeaten
Ethyn Ewing

Set For His Second UFC Bout
Rafael Estevam

Looks To Remain Undefeated
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF