X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Midwest Region Picks: March Madness Bracket Predictions

NCAA Tournament bracket picks and team predictions for the Midwest Region. Read Seth's March Madness picks, sleepers and busts including teams to target and avoid.

March Madness is officially here, so let's fill out some winning brackets! RotoBaller will be bringing you a full breakdown on each tournament region, including some potential sleepers and busts. Today we'll be taking a look at the Midwest Region and my bracket picks.

I'm here to tell you some teams that I believe in to help you make the right tournament bracket decisions. Below I analyze the top four seeds, a potential bust, and a potential final four candidate. Hopefully my college basketball predictions can help you win your March Madness brackets. Now let's get to it.

Editor's Note: Be sure to check out the rest of our NCAA Tournament articles and analysis, including a guide on how to fill out your brackets. Read our March Madness picks, sleepers, busts and predictions for the East, South, and West regions.

 

Midwest Region Top Four Seeds 

Top four seeds: No. 1 North Carolina, No. 2 Kentucky, No. 3 Houston, No. 4 Kansas

Carolina is the final one seed and some think Michigan State should've gotten that nod. Nevertheless, here we are and Carolina greatly benefits with a seemingly clear path to the Elite Eight. They are led by freshman-phenom point guard Coby White and senior big man Luke Maye. They are a well-rounded team.

Kentucky has lost three times since February (twice to Tennessee and once to LSU). When both Reid Travis and P.J. Washington are healthy, they are tough to beat. They are a bruising physical bunch. Their loss to Tennessee in the SEC semis may be the best thing to happen to them.

The odds are stacked against Houston. Top-three seeds unranked before the season have made the Final Four just two times out of 53 since the field expanded in 1986. Houston falls under that category. They have only lost three times all season and they could very well make the Elite Eight, but I'd be hesitant to put them in the Final Four.

Watching Kansas on the road and at home is like watching two different teams. They were 17-0 at home this season and 3-8 on the road. Now you may be wondering, why I'm talking about home and road stats when the NCAA Tournament is played only at neutral-sites. Well, the committee placed Kansas in the Midwest region and the Sweet 16 and Elite Eight are in Kansas City, MO. So if Kansas can get through the first weekend in Salt Lake City, UT, they'll have a major home-court advantage for the Sweet 16 and Elite Eight.

 

Most Intriguing First-Round Matchup: No. 7 Wofford vs. No. 10 Seton Hall

The Southern conference champs are on a 20-game winning streak without a single loss in their conference. They also are second in the nation in team three-point percentage. Ken Pomeroy even has them as the 19th-rated team. But they are running into a well-coached, gritty, and scrappy Seton Hall squad.

The Pirates have a great scorer in Myles Powell and the big bodies down low to hang with anyone. They may get behind in the first half, but I've seen them battle back far too often to ever count them out. I think the fact that Seton Hall has played in more close, grind-it-out games in bigger moments, will be the deciding factor against Wofford.

 

Bust of the Region

Kansas. I don't think they're getting out of the first weekend so they won't have the chance to play with a massive home-court advantage. They're an underwhelming team that is not your typical Kansas team.

 

Final Four Pick

Kentucky. The Wildcats are really good and losing in the SEC semifinals is probably the best thing that happened to them. They'd face Wofford/Seton Hall in the second round and while both teams are good, Kentucky will be too much. In the Sweet 16, Houston or Iowa State don't have the bodies to hang with Kentucky. In the Elite Eight, they'd most probably face North Carolina and at that point, it comes down to the last possession.

More March Madness Brackets Advice




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Detroit Lions

Dan Campbell to Call Offensive Plays for Rest of Lions Season
Calvin Ridley

Making his Return Against Texans
Quentin Johnston

Active in Week 11
Matthew Golden

Active for Week 11 Against Giants
Brian Thomas Jr.

Officially Ruled Out Against Chargers
Drake London

Officially Active to Face Panthers
A.J. Brown

Vows to Stop Complaining on Social Media
Keon Coleman

a Healthy Scratch for Non-Performance Reasons
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
Tua Tagovailoa

Future With Dolphins Tied to Mike McDaniel Returning
A.J. Brown

No Change in Philadelphia as A.J. Brown Still Frustrated
Viktor Arvidsson

Injured in Saturday's Win
Nick Foligno

Ruled Out for Four Weeks
Samuel Honzek

Hurt in Collision With Teammate
Drew Doughty

Exits With Lower-Body Injury
Charlie McAvoy

Sustains Upper-Body Injury Against Canadiens
Thomas Harley

Out Week-to-Week
Travis Hunter

to Remain a Two-Way Player in 2026
Bam Knight

is Expected to Play on Sunday
CFB

Virginia Tech Close To Naming James Franklin As Head Coach
C.J. Stroud

Week 12 Status Unclear
Quentin Johnston

Expected to Play in Week 11
Drake London

Should Play Vs. Panthers
Davante Adams

Trending Toward Playing
Brian Thomas Jr.

On the Wrong Side of Questionable
Calvin Ridley

Expected to Play in Week 11
Coby White

Could Make Season Debut Sunday
Josh Giddey

Set to Return Sunday
Zion Williamson

Tagged as Questionable for Sunday
Ja Morant

Exits With Calf Injury Saturday
Alex Caruso

Injures Hand, Won't Return Saturday
Domantas Sabonis

Considered Questionable for Sunday
Paolo Banchero

Out Again on Sunday
Anthony Davis

Listed as Doubtful for Sunday
Aaron Nesmith

Ruled Out for at Least Four Weeks
Victor Wembanyama

Questionable for Sunday
Tari Eason

to Miss 4-6 Weeks
Julian Strawther

Will Play on Saturday Versus the Timberwolves
Marcus Smart

Out With Illness Saturday
Cameron Johnson

Ruled Out on Saturday Evening
Rui Hachimura

Won't Play on Saturday
Giannis Antetokounmpo

Officially Available Versus the Lakers
Jeff Skinner

Placed on Injured Reserve
Nikola Jokić

Nikola Jokic Available on Saturday Night
Matt Duchene

Continues to Sit Saturday
Thomas Harley

a Game-Time Call Saturday
Kaapo Kakko

Out Week-to-Week
Joseph Woll

Starts on Saturday
John Carlson

Out on Saturday
Rasmus Dahlin

Rejoins Sabres Lineup Saturday
Jack Hughes

to Miss Eight Weeks After Finger Surgery
Luguentz Dort

Will Return Versus Charlotte
Darius Garland

Remains Out on Saturday Night
Zach Edey

Cleared to Make 2025 Debut on Saturday
Cedric Coward

Available Against Cleveland
Sam LaPorta

Placed on Injured Reserve
J.K. Dobbins

Will Undergo Season-Ending Surgery to Repair "Significant" Foot Injury
Tyler Bertuzzi

a Game-Time Call Saturday
Andre Burakovsky

Available Saturday
Alex Nedeljkovic

Available for Saturday's Action
Filip Hronek

Pulled by Concussion Spotter Friday
Jesperi Kotkaniemi

Hurts Ankle in Friday's Win
Seth Jarvis

Not Expected to Be Out for Long
CFB

Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

Blue Jays Interested in Signing Edwin Diaz?
Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
Aroldis Chapman

Named AL Reliever of the Year
Edwin Díaz

Edwin Diaz Named NL Reliever of the Year
NFL

Bill Belichick Won't Pursue NFL Head-Coaching Vacancies
John Gibson

Fine for Saturday
Justin Thomas

Will Miss Start Of 2026 After Undergoing Back Surgery
Islam Makhachev

Set For UFC 322 Main Event
Jack Della Maddalena

Set For His First Title Defense
Zhang Weili

Can Become The New Women's Flyweight Champion
Valentina Shevchenko

Set For UFC 322 Co-Main Event
Michael Morales

Looks To Remain Undefeated
CFB

Mario Craver a Game-Time Decision for Week 12
Sean Brady

Set For Title Eliminator Bout
Carlos Prates

A Favorite At UFC 322
Leon Edwards

Looks To Get Back In The Win Column
Benoît Saint Denis

Benoit Saint Denis Set To Open Up UFC 322 Main Card
Beneil Dariush

Looks To Win Back-To-Back Fights
CFB

Virginia's Chandler Morris Trending Toward Facing Duke on Saturday
Edwin Díaz

Edwin Diaz Says There's a "50-50" Chance he Returns to Mets
Shohei Ohtani

Wins his Fourth MVP Award
Aaron Judge

Wins AL MVP Award Again
Raisel Iglesias

Dodgers Interested in Signing Raisel Iglesias
Pete Alonso

Orioles Could be in the Mix to Sign Pete Alonso
Félix Bautista

Felix Bautista Could Return in Second Half in 2026
Kodai Senga

Attracting Trade Interest, Will the Mets Move him?
Yordan Alvarez

Expected to be Ready for Spring Training
Byron Buxton

Could Waive his No-Trade Clause
Paul Skenes

the Unanimous NL Cy Young Winner
Tarik Skubal

Wins AL Cy Young for Second Straight Year
CFB

Still No Update on Jermod McCoy's Return Timeline
Sami Valimaki

Riding Momentum Into Bermuda
Matthieu Pavon

Struggling Through a Rough Season
Taylor Montgomery

Hopes to Get Back on Track at Port Royal
Ben Martin

a Risky Play at Bermuda Championship
Mark Hubbard

Primed for a Bounce-Back Week in Bermuda
Lee Hodges

Searching for a Spark in Bermuda
Stephen Vogt

Wins Back-to-Back AL Manager of the Year Honors
Milwaukee Brewers

Pat Murphy Named NL Manager of the Year Again
Patrick Fishburn

Looking to Bounce Back in Bermuda
Eric Cole

Carrying Momentum into Bermuda
Tommy Edman

to Have Ankle Surgery Next Week
Ketel Marte

Diamondbacks Unlikely to Trade Ketel Marte
Roman Anthony

to Have a Normal Offseason
Sahith Theegala

Finishes Tied for 27th at Bank of Utah Championship
Sam Stevens

Finishes Tied for 36th at Baycurrent Classic
Patrick Rodgers

Finishes Tied For Sixth at World Wide Technology Championship
Luke List

Finishes 75th at World Wide Technology Championship
Ben Kohles

Finishes Tied for 63rd at World Wide Technology Championship
PGA

Nico Echavarria Finishes Tied for 14th at World Wide Technology Championship
Luke Clanton

Finishes Tied for 46th at World Wide Technology Championship
Blades Brown

Finishes Tied for 18th at Korn Ferry Tour Championship

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP