👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Midwest Region Picks: March Madness Bracket Predictions

NCAA Tournament bracket picks and team predictions for the Midwest Region. Read Seth's March Madness picks, sleepers and busts including teams to target and avoid.

March Madness is officially here, so let's fill out some winning brackets! RotoBaller will be bringing you a full breakdown on each tournament region, including some potential sleepers and busts. Today we'll be taking a look at the Midwest Region and my bracket picks.

I'm here to tell you some teams that I believe in to help you make the right tournament bracket decisions. Below I analyze the top four seeds, a potential bust, and a potential final four candidate. Hopefully my college basketball predictions can help you win your March Madness brackets. Now let's get to it.

Editor's Note: Be sure to check out the rest of our NCAA Tournament articles and analysis, including a guide on how to fill out your brackets. Read our March Madness picks, sleepers, busts and predictions for the East, South, and West regions.

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

Midwest Region Top Four Seeds 

Top four seeds: No. 1 North Carolina, No. 2 Kentucky, No. 3 Houston, No. 4 Kansas

Carolina is the final one seed and some think Michigan State should've gotten that nod. Nevertheless, here we are and Carolina greatly benefits with a seemingly clear path to the Elite Eight. They are led by freshman-phenom point guard Coby White and senior big man Luke Maye. They are a well-rounded team.

Kentucky has lost three times since February (twice to Tennessee and once to LSU). When both Reid Travis and P.J. Washington are healthy, they are tough to beat. They are a bruising physical bunch. Their loss to Tennessee in the SEC semis may be the best thing to happen to them.

The odds are stacked against Houston. Top-three seeds unranked before the season have made the Final Four just two times out of 53 since the field expanded in 1986. Houston falls under that category. They have only lost three times all season and they could very well make the Elite Eight, but I'd be hesitant to put them in the Final Four.

Watching Kansas on the road and at home is like watching two different teams. They were 17-0 at home this season and 3-8 on the road. Now you may be wondering, why I'm talking about home and road stats when the NCAA Tournament is played only at neutral-sites. Well, the committee placed Kansas in the Midwest region and the Sweet 16 and Elite Eight are in Kansas City, MO. So if Kansas can get through the first weekend in Salt Lake City, UT, they'll have a major home-court advantage for the Sweet 16 and Elite Eight.

 

Most Intriguing First-Round Matchup: No. 7 Wofford vs. No. 10 Seton Hall

The Southern conference champs are on a 20-game winning streak without a single loss in their conference. They also are second in the nation in team three-point percentage. Ken Pomeroy even has them as the 19th-rated team. But they are running into a well-coached, gritty, and scrappy Seton Hall squad.

The Pirates have a great scorer in Myles Powell and the big bodies down low to hang with anyone. They may get behind in the first half, but I've seen them battle back far too often to ever count them out. I think the fact that Seton Hall has played in more close, grind-it-out games in bigger moments, will be the deciding factor against Wofford.

 

Bust of the Region

Kansas. I don't think they're getting out of the first weekend so they won't have the chance to play with a massive home-court advantage. They're an underwhelming team that is not your typical Kansas team.

 

Final Four Pick

Kentucky. The Wildcats are really good and losing in the SEC semifinals is probably the best thing that happened to them. They'd face Wofford/Seton Hall in the second round and while both teams are good, Kentucky will be too much. In the Sweet 16, Houston or Iowa State don't have the bodies to hang with Kentucky. In the Elite Eight, they'd most probably face North Carolina and at that point, it comes down to the last possession.

More March Madness Brackets Advice




REAL-TIME FANTASY NEWS

Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
New York Giants

Giants Offense to be a Run-First Unit?
Joshua Palmer

Working Out on the Side at OTAs
Maxx Crosby

Raiders "Counting" on Maxx Crosby Being Ready for Training Camp
Kirk Cousins

the First Up in OTA Practice on Wednesday
Chicago Bulls

Jerry Stackhouse Emerges as Bulls Head-Coach Candidate
Cooper Flagg

Kon Knueppel Headline All-Rookie Team
De'Aaron Fox

is Ruled Out for Game 2 on Wednesday
Jiri Kulich

Aims to Return Next Season
Jeremy Lauzon

Not Expected to Play Wednesday
Brock Bowers

Klint Kubiak Calls Brock Bowers a "Football Robot From Heaven"
Mark Stone

Likely to Remain Out Wednesday
Scott Wedgewood

Starting Western Conference Finals for Avalanche
Sam Malinski

Set to Return Wednesday
Artturi Lehkonen

Expected to Play Wednesday Night
Cale Makar

Will Miss Game 1 Against Golden Knights
Malachi Fields

Appears Well-Positioned for Rookie Year Breakout in New York
Aaron Rodgers

Plans to Retire Following 2026 Season
Anthony Richardson Sr.

Is Anthony Richardson Sr. Worth Buying Low on in Deeper Dynasty Formats?
DJ Giddens

Does DJ Giddens Carry Dynasty Buy-Low Appeal into 2026?
AJ Barner

Enters 2026 as a Dynasty Sell-High Candidate
Josh Jacobs

Is Josh Jacobs at the Peak of His Dynasty Value?
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Wilson

Cardinals Interested in Inking Michael Wilson to a Long-Term Extension
Kyle Williams

Bulks Up, Ready to Make Year 2 Leap
Deshaun Watson

the First QB Up During OTA Drills on Wednesday
Quinshon Judkins

Taking Part in 11-on-11 Drills
Xavier Legette

Fighting for His Future in Carolina?
Brian Thomas Jr.

Jaguars Not Expected to Trade Brian Thomas Jr.
Rashod Bateman

Future in Baltimore is Bleak
Mark Andrews

Poised to Bounce Back in 2026?
Tyrone Tracy Jr.

Is Tyrone Tracy Jr. a Sneaky Dynasty Buy?
Chimere Dike

Dynasty Managers Compelled to Hold Chimere Dike?
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
James Harden

Struggles in Eastern Conference Finals Opener
Evan Mobley

Bags Second Consecutive Double-Double
Donovan Mitchell

Produces Top Two-Way Performance in Game 1 Loss
OG Anunoby

Plays Key Role in Comeback Win
Mikal Bridges

Remains Efficient in Game 1 Against Cavaliers
Karl-Anthony Towns

Extends Double-Double Streak to Four Games
Jalen Brunson

Leads Knicks to Historic Comeback Win
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Dean Wade

Returns to Starting Unit Tuesday
OG Anunoby

Starting on Tuesday
Tobias Harris

May Remain in Motown
Jalen Duren

Pistons Eager to Keep Jalen Duren
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Dallas Mavericks

Jason Kidd Fired as Mavericks Head Coach
De'Aaron Fox

Officially Listed as Questionable for Game 2 Against Thunder
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Quinn Hughes

Open to Signing Extension This Offseason
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF