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Thursday Night Football Matchups Analysis - Week 5

Thursday Night Football starts/sits and matchups analysis for Week 5 of the NFL season. Which Colts and Patriots to start or sit for fantasy football lineups.

Finally, football fans got the Thursday night shootout they were looking for! The Los Angeles Rams and Minnesota Vikings put up over 1,000 yards in total offense during their Thursday Night Football game in Week 4.

Fantasy owners who started most offensive pieces on either team were rewarded with a bevy of points to kick off the week, but it was those who started quarterback Jared Goff (465 passing yards, five touchdowns) and Cooper Kupp (162 receiving yards, two touchdowns) who were especially rewarded.

For this iteration of Thursday Night Football, the Indianapolis Colts are looking to rebound from a disappointing overtime loss while the New England Patriots will look to repeat their blowout win against the Miami Dolphins. Which players are worth slotting into your fantasy lineup? In not wasting any more time, let's dive into Thursday Night Football matchup analysis!

Editor's Note: The FFPC Playoff Challenge #2 is back with a massive $100,000 grand prize and $203,250 total prize pool, paying down to 100th place. Here's the deal: no salary cap, no draft, no pickups, no subs. Choose 8 players, and as NFL teams get knocked out so will your players, so choose your team wisely. The entries will sell out quickly, and registrations will close on Saturday January 17th at 4:30 pm ET . Don't wait - get your team now and end your fantasy football season with a shot at $100,000! Sign Up Now!

 

Indianapolis Colts @ New England Patriots

Date and Start Time: Thursday, October 4 at 8:20 PM ET

Notable Injuries and Status:

  • Marlon Mack (RB, IND) - Hamstring - Out
  • T.Y. Hilton (WR, IND) - Chest/Hamstring - Out
  • Jack Doyle (TE, IND) - Hip - Out
  • Darius Leonard (LB, IND) - Ankle - Questionable
  • Quincy Wilson (DB, IND) - Concussion - Out
  • Kenny Moore II (DB, IND) - Concussion - Out
  • Nate Hairston (DB, IND) - Various - Questionable
  • Josh Gordon (WR, NE) - Hamstring - Questionable
  • Rob Gronkowski (TE, NE) - Ankle - Questionable

 

Offensive and Defensive Rankings:

Colts Patriots
Passing Yards 16th 22nd
Rushing Yards 29th 12th
Pass Defense  18th 8th
Run  Defense  17th  26th

 

Must Starts

Top Performers That Have To Be In Your Lineup

Eric Ebron (TE, IND)

Assuming fellow tight end Jack Doyle sits this game out, Ebron gains a significant boost as arguably the Colts' No. 1 receiving option with wide receiver T.Y. Hilton expected to be out on a short week. While he hasn't been particularly effective at converting his boatload of targets into fantasy points, Ebron has scored in a touchdown in three of his last four games and will undoubtedly dominate red zone work.

Sony Michel (RB, NE)

The spike from 11 touches to 15 to 25 all but signals the Patriots' plans for their first-round rookie. With Rex Burkhead on injured reserve and out of the picture, Michel rushed for 112 yards and a touchdown in Week 4 and should be incredibly effective with his volume on Thursday night with the Colts defense hobbled by numerous injuries.

Rob Gronkowski (TE, NE)

If Gronkowski is able to play through his ankle injury, I shouldn't have to tell you he is a must-start at a position with a great deal of scarcity for prolific fantasy assets. With at least four catches across his last two games and the Colts top-three cornerbacks hobbled by injuries, Gronk should be able to bully his way to the end-zone at some point in this game.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Andrew Luck (QB, IND)

While Luck performed admirably in Week 4 with his favorite target T.Y. Hilton coming in and out of the game and has attempted at least 40 pass attempts in every game this season, it is hard to imagine the Colts having much success through the air considering their overall lack of weapons. Fantasy owners should consider Luck to be outside of the QB1 conversation for Thursday and look for better options if they are available.

Chester RogersZach Pascal (WRs, IND)

In accordance with quarterback Andrew Luck having a difficult hill to climb, the success of his No. 2 and No. 3 wide receivers will be highly unpredictable. Neither Chester Rogers nor Zach Pascal is a standout athlete, and making projections about who will draw enough targets to be fantasy-relevant may be an exercise in throwing darts. In deeper PPR leagues with roster crunches, these players could be worth a look. But this is a risky situation for fantasy owners to rely upon for their lineups.

Josh Gordon, Chris Hogan (WRs, NE)

Pending tight end Rob Gronkowski's availability in Week 5, one of Gordon or Hogan could experience a marked increase in touchdown upside considering the number of holes the Colts have in their secondary at present. Gordon's snap count is likely to remain severely limited as he learns the nuances of the playbook while Hogan has yet to top three catches or 50 receiving yards in a game this season. For fantasy purposes, it is a good idea to monitor Gronkowski's health leading up to the game if owners are in a must-start situation for Gordon or Hogan.

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Nyheim Hines (RB, IND)

Amid the inconsistent rotation of Colts running backs, Hines has successfully carved out a role as a receiver out of the backfield. The rookie rusher is averaging the fifth-most pass routes per game among running backs and is undoubtedly going to be involved in a game where the Colts could be trailing for a great deal of time.

Solid Option: Tom Brady (QB, NE)

The future Hall of Famer hasn't been quite so stellar in fantasy football, having yet to throw for over 300 yards in a game this season. Fortunately, Brady gets an exceptional bounce-back opportunity against a depleted Indianapolis Colts secondary. If his favorite target, tight end Rob Gronkowski, is able to play, most projections should slot Brady in as a QB1.

Solid Option: Julian Edelman (WR, NE)

Edelman returns from his four-game suspension ready to slide back into his role as a go-to slot receiver for the Patriots, meaning he draws immediate appeal in PPR formats despite the fact that he will need time to get used to being back on the field. He should see an immediate bump to his targets if tight end Rob Gronkowski is unable to play.

Solid Option: James White (RB, NE)

While the emergence of rookie running back Sony Michel is in the limelight, his backfield-mate has quietly accounted for an astonishing 26-percent of the New England fantasy production for skill players. The Colts defense at full strength has also been prone to giving up receptions to running backs, meaning White could be a sneaky play on Thursday.

Sleeper: Ryan Grant (WR, IND)

For fantasy owners in PPR leagues desperately looking for a plug-and-play option, Grant’s name should definitely be on your radar. While he hasn’t been able to come close to repeating a strong Week 1 performance where he led the team with eight receptions on nine targets, it is undeniable that he will be the most likely of the Colts wideouts to be peppered with targets now that T.Y. Hilton is confirmed to be sitting.

Sleeper: Phillip Dorsett (WR, NE)

Dorsett has probably been relegated to a lot of leagues' waiver wires now that the Patriots wide receiver room is looking awfully crowded. While it’s true that’s Josh Gordon is getting more comfortable with the playbook and Julian Edelman is returning from his suspension, it might be possible to squeeze one last ounce of fantasy production from Dorsett in a revenge game against his former team. His sure hands have resulted in quarterback Tom Brady targeting him at least seven times in three of his last four games and even with a decreased workload, Dorsett could be a WR3/4 play in deeper leagues before he fades into obscurity.

More Lineup Prep




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REAL-TIME FANTASY NEWS

Jerami Grant

May Miss Saturday's Game
Jrue Holiday

Questionable for Saturday
Aaron Gordon

Likely to Face Wizards
Jamal Murray

Listed as Probable for Saturday
Stephon Castle

Questionable for Saturday
Keon Ellis

Out Friday Night
Tari Eason

Still Out Friday
Deni Avdija

Unlikely to Play Against Lakers
Deandre Ayton

Questionable for Saturday's Tilt
Luka Dončić

Luka Doncic Won't Play Saturday
Domantas Sabonis

Officially Active Friday
Cade Cunningham

Considered Probable for Saturday
Jaime Jaquez Jr.

to Sit Out Second Consecutive Game
Tyler Herro

Questionable to Play Saturday
Jalen Brunson

Iffy for Meeting With Suns
Devin Booker

Uncertain for Saturday
Nicolas Batum

Starting Against Raptors
Julian Phillips

Returns From Two-Game Absence
Kevin Huerter

Available Against Nets
Ivica Zubac

Upgraded to Available
John Collins

Good to Go Friday
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Kevin Stefanski the Favorite for Falcons Head-Coaching Job
Matt Boldy

Placed on Injured Reserve
Ross Colton

Good to Go Friday
Will Smith

Returns Against Red Wings
Shayne Gostisbehere

Out Friday
Brad Marchand

Remains Out Friday
Joel Armia

Returns From Five-Game Absence
Chris Kreider

a Game-Time Call Friday
Troy Terry

Cutter Gauthier Available Friday
Leo Carlsson

Sits Out Second Consecutive Game
CFB

Darian Mensah Entering Transfer Portal
Sam Darnold

Seahawks "Optimistic" That Sam Darnold Will Play on Saturday
Nico Collins

Officially Ruled Out for Divisional Round
Rome Odunze

Questionable for Divisional Round
J.T. Realmuto

Signs Three-Year Deal to Return to Phillies
Bo Bichette

Agrees to Three-Year Contract With Mets
CFB

Weber State Signs former Ohio State, Cal Quarterback Devin Brown
Bo Bichette

Phillies the "Overwhelming" Favorite to Sign Bo Bichette
Mark Scheifele

Leads Jets to Victory Thursday
Tage Thompson

Records Season-High Five Points Thursday
Jack Eichel

Notches Four Points Thursday
Ilya Sorokin

Shuts Out Oilers With 35 Saves
Andrew Peeke

Not Expected to Be Out Long-Term
William Nylander

Aggravates Lower-Body Injury Thursday
Ross Colton

Uncertain for Friday
Josh Lowe

Angels Acquire Josh Lowe in Three-Team Trade
Kyle Tucker

Signs Four-Year Contract With Dodgers
Ricky Pearsall

Questionable to Play on Saturday Night
Sam Darnold

Questionable With Oblique Injury, Expected to Play
Damon Severson

Back for Blue Jackets Thursday
Adin Hill

Available Thursday Night
Brandon Montour

Activated From Injured Reserve
Joel Eriksson Ek

Misses Third Straight Game Thursday
Jonas Brodin

Placed on Injured Reserve, Out Week-to-Week
Clayton Kershaw

to Pitch for Team USA in World Baseball Classic
Patrick Mahomes

Says Rehab Going "Great," Goal is 2026 Week 1 Return
Nico Collins

a "Long Shot" to Play in Divisional Round
CFB

Auburn, Ohio State the Lead Suitors for Kyle Parker
CFB

Oregon QB Transfer Bryson Beaver Linked to Georgia, Kentucky
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Jake Merklinger Commits to UConn
New York Giants

John Harbaugh Finalizing Deal With Giants
Ben Griffin

Looks To Stay Hot In 2026
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Giants Making "Massive Push" to Hire John Harbaugh on Wednesday
Ranger Suárez

Ranger Suarez Agrees to Five-Year Deal With Red Sox
CFB

Dante Moore Not Entering 2026 NFL Draft, Will Return to Oregon
NFL

Mike Tomlin Doesn't Plan to Coach in 2026
Travis Hunter

Expected to Play More Defense in 2026
CFB

FBS Coaches Unanimously Vote to Expand Redshirt Eligibility to Nine Games
CFB

Ohio State Transfer Mylan Graham Signs with Notre Dame
CFB

Caden Durham Withdraws from Transfer Portal, Will Stay at LSU
Jordan Spieth

Perhaps the Most Intriguing Player at Sony Open
Aaron Rai

Looking For Putting Confidence at Waialae Country Club
Collin Morikawa

Isn't The Safe Play He Used to Be Ahead of Sony Open
Kurt Kitayama

Needs His Putting to Turn Around For Success at Year's First Event
Ryan Weathers

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Chargers Fire Offensive Coordinator Greg Roman
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Mike Tomlin Stepping Down as Steelers Head Coach
CFB

Georgia Tech the Favorite to Land Justice Haynes?
Nolan Arenado

Cardinals Trade Nolan Arenado to Diamondbacks
Tom Kim

Desperately Needs a Solid Week at Sony Open
Billy Horschel

Hoping For a Fast Start to New Season at Sony Open
Corey Conners

Looks to Have a Return to Form in 2026
PGA

Chris Gotterup a Decent Play at Sony Open
Gary Woodland

Could Prosper at the Sony Open
Keith Mitchell

Unlikely to Contend at Sony Open
Robert MacIntyre

Looking for a Good Performance at the Sony Open
Michael Kim

Hopes to Start Sony Open Better This Week
Tom Hoge

Tries to Erase Poor 2025 Second Half in Hawaii
Brian Harman

Seeks Fresh Start in Hawaii
Eric Cole

Looks to Last Year for Success at Sony Open
Daniel Berger

Starts Off 2026 at Sony Open
Nico Collins

Suffers Concussion Against Steelers
Nico Collins

Carted to Locker Room for Concussion Evaluation
Kyle Tucker

Mets Meet With Kyle Tucker
Dalton Kincaid

"Should be Fine" for Divisional Round
Brooks Koepka

Officially Returning To PGA Tour
Tucker Kraft

Hopes to be Ready for Week 1 of Next Season
CFB

Georgia Lands Kentucky Transfer Dante Dowdell
Matthew Stafford

has "Little Sprain," Should be "Good to Go"
CFB

Sam Leavitt Expected to Sign with LSU
Green Bay Packers

Packers Expected to Work Out New Deal With Matt LaFleur in the "Coming Days"
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Dylan Raiola Commits to Oregon
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Isaiah Horton Landing with Texas A&M
George Kittle

Suffers Torn Achilles on Sunday

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP