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Thursday Night Football Matchups Analysis - Week 5

Thursday Night Football starts/sits and matchups analysis for Week 5 of the NFL season. Which Colts and Patriots to start or sit for fantasy football lineups.

Finally, football fans got the Thursday night shootout they were looking for! The Los Angeles Rams and Minnesota Vikings put up over 1,000 yards in total offense during their Thursday Night Football game in Week 4.

Fantasy owners who started most offensive pieces on either team were rewarded with a bevy of points to kick off the week, but it was those who started quarterback Jared Goff (465 passing yards, five touchdowns) and Cooper Kupp (162 receiving yards, two touchdowns) who were especially rewarded.

For this iteration of Thursday Night Football, the Indianapolis Colts are looking to rebound from a disappointing overtime loss while the New England Patriots will look to repeat their blowout win against the Miami Dolphins. Which players are worth slotting into your fantasy lineup? In not wasting any more time, let's dive into Thursday Night Football matchup analysis!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Indianapolis Colts @ New England Patriots

Date and Start Time: Thursday, October 4 at 8:20 PM ET

Notable Injuries and Status:

  • Marlon Mack (RB, IND) - Hamstring - Out
  • T.Y. Hilton (WR, IND) - Chest/Hamstring - Out
  • Jack Doyle (TE, IND) - Hip - Out
  • Darius Leonard (LB, IND) - Ankle - Questionable
  • Quincy Wilson (DB, IND) - Concussion - Out
  • Kenny Moore II (DB, IND) - Concussion - Out
  • Nate Hairston (DB, IND) - Various - Questionable
  • Josh Gordon (WR, NE) - Hamstring - Questionable
  • Rob Gronkowski (TE, NE) - Ankle - Questionable

 

Offensive and Defensive Rankings:

Colts Patriots
Passing Yards 16th 22nd
Rushing Yards 29th 12th
Pass Defense  18th 8th
Run  Defense  17th  26th

 

Must Starts

Top Performers That Have To Be In Your Lineup

Eric Ebron (TE, IND)

Assuming fellow tight end Jack Doyle sits this game out, Ebron gains a significant boost as arguably the Colts' No. 1 receiving option with wide receiver T.Y. Hilton expected to be out on a short week. While he hasn't been particularly effective at converting his boatload of targets into fantasy points, Ebron has scored in a touchdown in three of his last four games and will undoubtedly dominate red zone work.

Sony Michel (RB, NE)

The spike from 11 touches to 15 to 25 all but signals the Patriots' plans for their first-round rookie. With Rex Burkhead on injured reserve and out of the picture, Michel rushed for 112 yards and a touchdown in Week 4 and should be incredibly effective with his volume on Thursday night with the Colts defense hobbled by numerous injuries.

Rob Gronkowski (TE, NE)

If Gronkowski is able to play through his ankle injury, I shouldn't have to tell you he is a must-start at a position with a great deal of scarcity for prolific fantasy assets. With at least four catches across his last two games and the Colts top-three cornerbacks hobbled by injuries, Gronk should be able to bully his way to the end-zone at some point in this game.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Andrew Luck (QB, IND)

While Luck performed admirably in Week 4 with his favorite target T.Y. Hilton coming in and out of the game and has attempted at least 40 pass attempts in every game this season, it is hard to imagine the Colts having much success through the air considering their overall lack of weapons. Fantasy owners should consider Luck to be outside of the QB1 conversation for Thursday and look for better options if they are available.

Chester RogersZach Pascal (WRs, IND)

In accordance with quarterback Andrew Luck having a difficult hill to climb, the success of his No. 2 and No. 3 wide receivers will be highly unpredictable. Neither Chester Rogers nor Zach Pascal is a standout athlete, and making projections about who will draw enough targets to be fantasy-relevant may be an exercise in throwing darts. In deeper PPR leagues with roster crunches, these players could be worth a look. But this is a risky situation for fantasy owners to rely upon for their lineups.

Josh Gordon, Chris Hogan (WRs, NE)

Pending tight end Rob Gronkowski's availability in Week 5, one of Gordon or Hogan could experience a marked increase in touchdown upside considering the number of holes the Colts have in their secondary at present. Gordon's snap count is likely to remain severely limited as he learns the nuances of the playbook while Hogan has yet to top three catches or 50 receiving yards in a game this season. For fantasy purposes, it is a good idea to monitor Gronkowski's health leading up to the game if owners are in a must-start situation for Gordon or Hogan.

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Nyheim Hines (RB, IND)

Amid the inconsistent rotation of Colts running backs, Hines has successfully carved out a role as a receiver out of the backfield. The rookie rusher is averaging the fifth-most pass routes per game among running backs and is undoubtedly going to be involved in a game where the Colts could be trailing for a great deal of time.

Solid Option: Tom Brady (QB, NE)

The future Hall of Famer hasn't been quite so stellar in fantasy football, having yet to throw for over 300 yards in a game this season. Fortunately, Brady gets an exceptional bounce-back opportunity against a depleted Indianapolis Colts secondary. If his favorite target, tight end Rob Gronkowski, is able to play, most projections should slot Brady in as a QB1.

Solid Option: Julian Edelman (WR, NE)

Edelman returns from his four-game suspension ready to slide back into his role as a go-to slot receiver for the Patriots, meaning he draws immediate appeal in PPR formats despite the fact that he will need time to get used to being back on the field. He should see an immediate bump to his targets if tight end Rob Gronkowski is unable to play.

Solid Option: James White (RB, NE)

While the emergence of rookie running back Sony Michel is in the limelight, his backfield-mate has quietly accounted for an astonishing 26-percent of the New England fantasy production for skill players. The Colts defense at full strength has also been prone to giving up receptions to running backs, meaning White could be a sneaky play on Thursday.

Sleeper: Ryan Grant (WR, IND)

For fantasy owners in PPR leagues desperately looking for a plug-and-play option, Grant’s name should definitely be on your radar. While he hasn’t been able to come close to repeating a strong Week 1 performance where he led the team with eight receptions on nine targets, it is undeniable that he will be the most likely of the Colts wideouts to be peppered with targets now that T.Y. Hilton is confirmed to be sitting.

Sleeper: Phillip Dorsett (WR, NE)

Dorsett has probably been relegated to a lot of leagues' waiver wires now that the Patriots wide receiver room is looking awfully crowded. While it’s true that’s Josh Gordon is getting more comfortable with the playbook and Julian Edelman is returning from his suspension, it might be possible to squeeze one last ounce of fantasy production from Dorsett in a revenge game against his former team. His sure hands have resulted in quarterback Tom Brady targeting him at least seven times in three of his last four games and even with a decreased workload, Dorsett could be a WR3/4 play in deeper leagues before he fades into obscurity.

More Lineup Prep




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Kyle Schwarber

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Clay Holmes

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Blake Snell

Heads to 15-Day Injured List
Austin Reaves

Could Command $40M Per Year With New Contract
Jalen Duren

Available to Finish Game 6
Yanic Konan Niederhauser

Not Expected to Be Ready for Start of Next Season
Jalen Williams

Declares Himself Healthy for Conference Finals
Terrence Shannon Jr.

Will Play Friday Night
Kevin Huerter

is Available for Game 6
Duncan Robinson

is Returning for Game 6
Caris LeVert

is Cleared for Game 6 on Friday
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Practices in Full on Friday
Terrence Shannon Jr.

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Scratched From Start on Friday for Undisclosed Reasons
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College GameDay Set for First Three Weeks
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Keshaun Singleton Projects as Auburn's WR1
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Jeremiah Cobb Impresses New Auburn Staff
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Alberto Mendoza Very Likely to Start for Georgia Tech
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Charles Woodson Jr. Commits to Michigan
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Dynasty Outlook Remains Cloudy
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Quickly Fading From Fantasy Relevance
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Not the Primary Option in New System?
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Still Time to Buy Low on Kyle Monangai in Dynasty Leagues?
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Resumes Playing Catch, Ahead of Schedule?
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an Unheralded Dynasty Cornerstone
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Making an Impact as Playmaker in Playoffs
Jalen Duren

Determined to Improve
Kevin Huerter

Tagged as Questionable for Game 6 Against Cavaliers
Caris LeVert

Considered Questionable for Friday
Duncan Robinson

Iffy for Game 6
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
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Enjoys Second Consecutive Multi-Goal Game
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Records Two Points in Game 6 Win
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Scores Special Goal in Series-Clincher
Ryan Johnson

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Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

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Kris Knoblauch Fired as Oilers Head Coach
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Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Paul Reed

Makes Big Impact Off the Bench Wednesday
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Jarrett Allen

Records Double-Double in Game 5 Win
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
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Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
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NFL Veteran Tom Moore Joins Iowa Coaching Staff
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Kwazi Gilmer Set for Big Impact at Nebraska
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Patrick Reed

Looking to Make Another Run at PGA Championship
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Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

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Brandt Snedeker

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Rasmus Hojgaard

a Volatile Option at PGA Championship
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Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
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Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
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Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
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Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
CFB

Isaac Brown Has All-American Upside in 2026
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Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
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Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
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Dominates Watkins Glen for First Win of 2026
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Finishes Second for Best Run of the Year At Watkins Glen
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Scores New Career-Best Finish of Third at Watkins Glen
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Continues His Strong Season With Fifth-Place Run at Watkins Glen
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Earns his First Top-10 Finish of 2026 at Watkins Glen
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Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
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Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
William Byron

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Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
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A.J. Allmendinger May have Another Solid Outing at Watkins Glen
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Ross Chastain

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RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF