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Thursday Night Football Matchups Analysis - Week 5

Thursday Night Football starts/sits and matchups analysis for Week 5 of the NFL season. Which Colts and Patriots to start or sit for fantasy football lineups.

Finally, football fans got the Thursday night shootout they were looking for! The Los Angeles Rams and Minnesota Vikings put up over 1,000 yards in total offense during their Thursday Night Football game in Week 4.

Fantasy owners who started most offensive pieces on either team were rewarded with a bevy of points to kick off the week, but it was those who started quarterback Jared Goff (465 passing yards, five touchdowns) and Cooper Kupp (162 receiving yards, two touchdowns) who were especially rewarded.

For this iteration of Thursday Night Football, the Indianapolis Colts are looking to rebound from a disappointing overtime loss while the New England Patriots will look to repeat their blowout win against the Miami Dolphins. Which players are worth slotting into your fantasy lineup? In not wasting any more time, let's dive into Thursday Night Football matchup analysis!

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Indianapolis Colts @ New England Patriots

Date and Start Time: Thursday, October 4 at 8:20 PM ET

Notable Injuries and Status:

  • Marlon Mack (RB, IND) - Hamstring - Out
  • T.Y. Hilton (WR, IND) - Chest/Hamstring - Out
  • Jack Doyle (TE, IND) - Hip - Out
  • Darius Leonard (LB, IND) - Ankle - Questionable
  • Quincy Wilson (DB, IND) - Concussion - Out
  • Kenny Moore II (DB, IND) - Concussion - Out
  • Nate Hairston (DB, IND) - Various - Questionable
  • Josh Gordon (WR, NE) - Hamstring - Questionable
  • Rob Gronkowski (TE, NE) - Ankle - Questionable

 

Offensive and Defensive Rankings:

Colts Patriots
Passing Yards 16th 22nd
Rushing Yards 29th 12th
Pass Defense  18th 8th
Run  Defense  17th  26th

 

Must Starts

Top Performers That Have To Be In Your Lineup

Eric Ebron (TE, IND)

Assuming fellow tight end Jack Doyle sits this game out, Ebron gains a significant boost as arguably the Colts' No. 1 receiving option with wide receiver T.Y. Hilton expected to be out on a short week. While he hasn't been particularly effective at converting his boatload of targets into fantasy points, Ebron has scored in a touchdown in three of his last four games and will undoubtedly dominate red zone work.

Sony Michel (RB, NE)

The spike from 11 touches to 15 to 25 all but signals the Patriots' plans for their first-round rookie. With Rex Burkhead on injured reserve and out of the picture, Michel rushed for 112 yards and a touchdown in Week 4 and should be incredibly effective with his volume on Thursday night with the Colts defense hobbled by numerous injuries.

Rob Gronkowski (TE, NE)

If Gronkowski is able to play through his ankle injury, I shouldn't have to tell you he is a must-start at a position with a great deal of scarcity for prolific fantasy assets. With at least four catches across his last two games and the Colts top-three cornerbacks hobbled by injuries, Gronk should be able to bully his way to the end-zone at some point in this game.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Andrew Luck (QB, IND)

While Luck performed admirably in Week 4 with his favorite target T.Y. Hilton coming in and out of the game and has attempted at least 40 pass attempts in every game this season, it is hard to imagine the Colts having much success through the air considering their overall lack of weapons. Fantasy owners should consider Luck to be outside of the QB1 conversation for Thursday and look for better options if they are available.

Chester RogersZach Pascal (WRs, IND)

In accordance with quarterback Andrew Luck having a difficult hill to climb, the success of his No. 2 and No. 3 wide receivers will be highly unpredictable. Neither Chester Rogers nor Zach Pascal is a standout athlete, and making projections about who will draw enough targets to be fantasy-relevant may be an exercise in throwing darts. In deeper PPR leagues with roster crunches, these players could be worth a look. But this is a risky situation for fantasy owners to rely upon for their lineups.

Josh Gordon, Chris Hogan (WRs, NE)

Pending tight end Rob Gronkowski's availability in Week 5, one of Gordon or Hogan could experience a marked increase in touchdown upside considering the number of holes the Colts have in their secondary at present. Gordon's snap count is likely to remain severely limited as he learns the nuances of the playbook while Hogan has yet to top three catches or 50 receiving yards in a game this season. For fantasy purposes, it is a good idea to monitor Gronkowski's health leading up to the game if owners are in a must-start situation for Gordon or Hogan.

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Nyheim Hines (RB, IND)

Amid the inconsistent rotation of Colts running backs, Hines has successfully carved out a role as a receiver out of the backfield. The rookie rusher is averaging the fifth-most pass routes per game among running backs and is undoubtedly going to be involved in a game where the Colts could be trailing for a great deal of time.

Solid Option: Tom Brady (QB, NE)

The future Hall of Famer hasn't been quite so stellar in fantasy football, having yet to throw for over 300 yards in a game this season. Fortunately, Brady gets an exceptional bounce-back opportunity against a depleted Indianapolis Colts secondary. If his favorite target, tight end Rob Gronkowski, is able to play, most projections should slot Brady in as a QB1.

Solid Option: Julian Edelman (WR, NE)

Edelman returns from his four-game suspension ready to slide back into his role as a go-to slot receiver for the Patriots, meaning he draws immediate appeal in PPR formats despite the fact that he will need time to get used to being back on the field. He should see an immediate bump to his targets if tight end Rob Gronkowski is unable to play.

Solid Option: James White (RB, NE)

While the emergence of rookie running back Sony Michel is in the limelight, his backfield-mate has quietly accounted for an astonishing 26-percent of the New England fantasy production for skill players. The Colts defense at full strength has also been prone to giving up receptions to running backs, meaning White could be a sneaky play on Thursday.

Sleeper: Ryan Grant (WR, IND)

For fantasy owners in PPR leagues desperately looking for a plug-and-play option, Grant’s name should definitely be on your radar. While he hasn’t been able to come close to repeating a strong Week 1 performance where he led the team with eight receptions on nine targets, it is undeniable that he will be the most likely of the Colts wideouts to be peppered with targets now that T.Y. Hilton is confirmed to be sitting.

Sleeper: Phillip Dorsett (WR, NE)

Dorsett has probably been relegated to a lot of leagues' waiver wires now that the Patriots wide receiver room is looking awfully crowded. While it’s true that’s Josh Gordon is getting more comfortable with the playbook and Julian Edelman is returning from his suspension, it might be possible to squeeze one last ounce of fantasy production from Dorsett in a revenge game against his former team. His sure hands have resulted in quarterback Tom Brady targeting him at least seven times in three of his last four games and even with a decreased workload, Dorsett could be a WR3/4 play in deeper leagues before he fades into obscurity.

More Lineup Prep




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REAL-TIME FANTASY NEWS

Amen Thompson

Not on the Injury Report for Thursday
Merrill Kelly

Diamondbacks Holding Out Hope Merrill Kelly Can Avoid the Injured List
Jalen Johnson

Listed as Out on Thursday
Tristan Vukcevic

Will be Available on Thursday
Samuel Basallo

Dealing With Abdominal Discomfort
Kyshawn George

Ruled Out Against Atlanta
Konnor Griffin

"Trending Toward Being" Opening Day Shortstop
Lauri Markkanen

Will Not Play Thursday
Norman Powell

Downgraded to Questionable Thursday Against the 76ers
Jamir Watkins

Signs a Two-Year Deal with Washington
Royce Lewis

Scratched With Tightness in his Side
Ashton Jeanty

Not in Line for Workhorse Role in 2026?
Samuel Basallo

Injured in Spring Game on Thursday
Ryan Weathers

Looks Sharp in Spring Debut
Mike Trout

Moving Around the Outfield This Spring
Nick Kurtz

A's Offer Long-Term Extension to Nick Kurtz
Shane McClanahan

to Make Spring Debut on Tuesday
Anthony Richardson Sr.

Colts Give Anthony Richardson Sr. Permission to Seek a Trade
Brenton Doyle

Undergoes Imaging on his Wrist
Yuki Matsui

Ruled Out for World Baseball Classic
Pablo López

Pablo Lopez Undergoes Internal-Brace Procedure
Roki Sasaki

Hit Hard in Spring Debut
Yordan Alvarez

to Make Spring Debut Next Week
Josh Hader

Remains Without a Timetable to Return
Giancarlo Stanton

Still Dealing With Elbow Pain, Hopes to Play Full Season
Pete Fairbanks

Stepping into His Role as Marlins Closer
Colin Poche

Tigers Sign Colin Poche to Minor-League Deal
Brendan Rodgers

Will Have an MRI Thursday
Max Scherzer

Returns to Blue Jays on One-Year Deal
Daniel Gafford

Doubtful Versus Kings
Brock Nelson

Produces 30th Goal of the Campaign
Lauri Markkanen

Questionable Against Pelicans
P.J. Washington

Won't Play Thursday Against Kings
Nikita Kucherov

Extends Point Streak to 11 Games
Branden Carlson

Exits Early with Back Issue
Tage Thompson

Leads Sabres Past Devils
Isaiah Joe

Exits Early with Glute Injury
Wyatt Johnston

Pots Two Goals in Wednesday's Win
Collin Murray-Boyles

Leaves Game After Aggravating Thumb
Ryan Lindgren

Exits Early Wednesday
Alex Newhook

Expected to Return Thursday
Jamal Murray

Leaves Game After Eight Minutes
Robert Thomas

Takes Leave of Absence
Kyshawn George

Questionable Thursday
Zaccharie Risacher

Dealing With Hip Issue, Questionable for Thursday
Nickeil Alexander-Walker

Tagged as Questionable for Thursday
Jalen Suggs

Could Be Out for Fourth Straight Game
Andrew Nembhard

Iffy Thursday
Deni Avdija

Remains Sidelined Thursday
Kawhi Leonard

Questionable to Suit Up Thursday
Randal Grichuk

Joins Yankees on Minor-League Deal
Kyler Murray

Prefers to be Released
Derek Carr

"Strong Belief" That Derek Carr is "Very Serious" About Unretiring
Mikael Granlund

Leo Carlsson In, Mikael Granlund Out for Ducks Wednesday
Connor McDavid

Ready to Play Wednesday
John Carlson

Out Wednesday
Roope Hintz

Misses Wednesday's Action Due to Illness
Shea Theodore

Unavailable Wednesday
Mark Stone

Mitch Marner Won't Play Wednesday
Logan Cooley

on Track to Return Wednesday
Sidney Crosby

Set to Miss Four Weeks
Andy Dalton

Is Andy Dalton Available for a Trade?
Keith Mitchell

Making The Comfortable Return to PGA National
CFB

Chandler Morris Suing NCAA for Seventh Year of Eligibility
Chris Kirk

Searching for a Spark at Cognizant Classic
Brooks Koepka

Making Third PGA Tour Start at Cognizant Classic
Mackenzie Hughes

a Steady Option at Cognizant Classic
Seamus Power

Seeking More Green in Florida
PGA

Haotong Li Back From a Break as Florida Stretch Starts
Stephan Jaeger

Trying to Put Four Rounds Together in Florida
PGA

Nico Echavarria Again Attempting to Make the Weekend
Patrick Fishburn

Looking for a Spark at Cognizant Classic
Blades Brown

Set for Cognizant Classic Debut
Michael Thorbjornsen

Looking to Bounce Back at Cognizant Classic
Maxx Crosby

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Nino Niederreiter

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Unavailable Wednesday
Jack Eichel

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John Tavares

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Samuel Girard

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Looks to Improve Season at Cognizant Classic
Kyle Pitts Sr.

Falcons Place Franchise Tag on Kyle Pitts Sr.
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Returns to Defend at Cognizant Classic
Quinshon Judkins

Out of Walking Boot, Will be Ready for Training Camp
Breece Hall

Jets Will Use Franchise Tag on Breece Hall if Extension isn't Reached
Joel Dahmen

Needs Better Consistency Heading Into The Florida Swing
Daniel Berger

Looks to Improve Putting as PGA Tour Begins Its Florida Swing
Kirk Cousins

Falcons Plan to Release Kirk Cousins
Zach Ertz

Plans to Return for 14th Season
Davis Thompson

Struggling to Find Birdies as Florida Looms
Tom Kim

Not Quite Cutting It in 2026
Nicolai Hojgaard

Wants to Build Momentum from Scottsdale
Christiaan Bezuidenhout

Returns After Extended Break for Florida Event
CFB

Gunner Rivers Follows His Father, Commits To North Carolina State
Will Zalatoris

Set to Make Tournament Debut at Cognizant Classic
Rasmus Hojgaard

Trending Up at the Cognizant Classic
Anthony Hernandez

Suffers Third-Round TKO Loss
Sean Strickland

Gets Back In The Win Column
Kyle Pitts Sr.

Falcons Planning to Use Franchise Tag on Kyle Pitts Sr.
Geoff Neal

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Uros Medic

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Dan Ige

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Bubba Wallace Falls Short of Victory at EchoPark Speedway
Carson Hocevar

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Ross Chastain

Finishes Third At EchoPark Speedway
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Tyler Reddick

Nabs His Second Win of the Season At EchoPark Speedway
Joey Logano

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Tyler Reddick

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Chase Elliott

Could Chase Elliott Be Worth Rostering At EchoPark Speedway?
Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at EchoPark Speedway?
William Byron

Is William Byron Worth Rostering for DFS at EchoPark Speedway?
Rondale Moore

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Denny Hamlin

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Brad Keselowski

Is A Tournament Option for DFS At EchoPark Speedway
NASCAR

Is Bubba Wallace Rosterable In DFS At EchoPark Speedway?
Austin Cindric

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Ross Chastain

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Ricky Stenhouse Jr

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Alex Bowman

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Javonte Williams

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Travis Etienne Jr.

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Zach Charbonnet

Undergoes Knee Surgery on Friday
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