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Thursday Night Football Matchups Analysis - Week 5

Thursday Night Football starts/sits and matchups analysis for Week 5 of the NFL season. Which Colts and Patriots to start or sit for fantasy football lineups.

Finally, football fans got the Thursday night shootout they were looking for! The Los Angeles Rams and Minnesota Vikings put up over 1,000 yards in total offense during their Thursday Night Football game in Week 4.

Fantasy owners who started most offensive pieces on either team were rewarded with a bevy of points to kick off the week, but it was those who started quarterback Jared Goff (465 passing yards, five touchdowns) and Cooper Kupp (162 receiving yards, two touchdowns) who were especially rewarded.

For this iteration of Thursday Night Football, the Indianapolis Colts are looking to rebound from a disappointing overtime loss while the New England Patriots will look to repeat their blowout win against the Miami Dolphins. Which players are worth slotting into your fantasy lineup? In not wasting any more time, let's dive into Thursday Night Football matchup analysis!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Indianapolis Colts @ New England Patriots

Date and Start Time: Thursday, October 4 at 8:20 PM ET

Notable Injuries and Status:

  • Marlon Mack (RB, IND) - Hamstring - Out
  • T.Y. Hilton (WR, IND) - Chest/Hamstring - Out
  • Jack Doyle (TE, IND) - Hip - Out
  • Darius Leonard (LB, IND) - Ankle - Questionable
  • Quincy Wilson (DB, IND) - Concussion - Out
  • Kenny Moore II (DB, IND) - Concussion - Out
  • Nate Hairston (DB, IND) - Various - Questionable
  • Josh Gordon (WR, NE) - Hamstring - Questionable
  • Rob Gronkowski (TE, NE) - Ankle - Questionable

 

Offensive and Defensive Rankings:

Colts Patriots
Passing Yards 16th 22nd
Rushing Yards 29th 12th
Pass Defense  18th 8th
Run  Defense  17th  26th

 

Must Starts

Top Performers That Have To Be In Your Lineup

Eric Ebron (TE, IND)

Assuming fellow tight end Jack Doyle sits this game out, Ebron gains a significant boost as arguably the Colts' No. 1 receiving option with wide receiver T.Y. Hilton expected to be out on a short week. While he hasn't been particularly effective at converting his boatload of targets into fantasy points, Ebron has scored in a touchdown in three of his last four games and will undoubtedly dominate red zone work.

Sony Michel (RB, NE)

The spike from 11 touches to 15 to 25 all but signals the Patriots' plans for their first-round rookie. With Rex Burkhead on injured reserve and out of the picture, Michel rushed for 112 yards and a touchdown in Week 4 and should be incredibly effective with his volume on Thursday night with the Colts defense hobbled by numerous injuries.

Rob Gronkowski (TE, NE)

If Gronkowski is able to play through his ankle injury, I shouldn't have to tell you he is a must-start at a position with a great deal of scarcity for prolific fantasy assets. With at least four catches across his last two games and the Colts top-three cornerbacks hobbled by injuries, Gronk should be able to bully his way to the end-zone at some point in this game.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Andrew Luck (QB, IND)

While Luck performed admirably in Week 4 with his favorite target T.Y. Hilton coming in and out of the game and has attempted at least 40 pass attempts in every game this season, it is hard to imagine the Colts having much success through the air considering their overall lack of weapons. Fantasy owners should consider Luck to be outside of the QB1 conversation for Thursday and look for better options if they are available.

Chester RogersZach Pascal (WRs, IND)

In accordance with quarterback Andrew Luck having a difficult hill to climb, the success of his No. 2 and No. 3 wide receivers will be highly unpredictable. Neither Chester Rogers nor Zach Pascal is a standout athlete, and making projections about who will draw enough targets to be fantasy-relevant may be an exercise in throwing darts. In deeper PPR leagues with roster crunches, these players could be worth a look. But this is a risky situation for fantasy owners to rely upon for their lineups.

Josh Gordon, Chris Hogan (WRs, NE)

Pending tight end Rob Gronkowski's availability in Week 5, one of Gordon or Hogan could experience a marked increase in touchdown upside considering the number of holes the Colts have in their secondary at present. Gordon's snap count is likely to remain severely limited as he learns the nuances of the playbook while Hogan has yet to top three catches or 50 receiving yards in a game this season. For fantasy purposes, it is a good idea to monitor Gronkowski's health leading up to the game if owners are in a must-start situation for Gordon or Hogan.

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Nyheim Hines (RB, IND)

Amid the inconsistent rotation of Colts running backs, Hines has successfully carved out a role as a receiver out of the backfield. The rookie rusher is averaging the fifth-most pass routes per game among running backs and is undoubtedly going to be involved in a game where the Colts could be trailing for a great deal of time.

Solid Option: Tom Brady (QB, NE)

The future Hall of Famer hasn't been quite so stellar in fantasy football, having yet to throw for over 300 yards in a game this season. Fortunately, Brady gets an exceptional bounce-back opportunity against a depleted Indianapolis Colts secondary. If his favorite target, tight end Rob Gronkowski, is able to play, most projections should slot Brady in as a QB1.

Solid Option: Julian Edelman (WR, NE)

Edelman returns from his four-game suspension ready to slide back into his role as a go-to slot receiver for the Patriots, meaning he draws immediate appeal in PPR formats despite the fact that he will need time to get used to being back on the field. He should see an immediate bump to his targets if tight end Rob Gronkowski is unable to play.

Solid Option: James White (RB, NE)

While the emergence of rookie running back Sony Michel is in the limelight, his backfield-mate has quietly accounted for an astonishing 26-percent of the New England fantasy production for skill players. The Colts defense at full strength has also been prone to giving up receptions to running backs, meaning White could be a sneaky play on Thursday.

Sleeper: Ryan Grant (WR, IND)

For fantasy owners in PPR leagues desperately looking for a plug-and-play option, Grant’s name should definitely be on your radar. While he hasn’t been able to come close to repeating a strong Week 1 performance where he led the team with eight receptions on nine targets, it is undeniable that he will be the most likely of the Colts wideouts to be peppered with targets now that T.Y. Hilton is confirmed to be sitting.

Sleeper: Phillip Dorsett (WR, NE)

Dorsett has probably been relegated to a lot of leagues' waiver wires now that the Patriots wide receiver room is looking awfully crowded. While it’s true that’s Josh Gordon is getting more comfortable with the playbook and Julian Edelman is returning from his suspension, it might be possible to squeeze one last ounce of fantasy production from Dorsett in a revenge game against his former team. His sure hands have resulted in quarterback Tom Brady targeting him at least seven times in three of his last four games and even with a decreased workload, Dorsett could be a WR3/4 play in deeper leagues before he fades into obscurity.

More Lineup Prep




REAL-TIME FANTASY NEWS

Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Tanner Koziol

a Long-Shot Dynasty Tight End?
Dylan Cease

Heading to Injured List With Hamstring Injury
Kevin Coleman Jr.

in the Right Place for Opportunities
Josh Cameron

has Long-Term YAC Upside in Liam Coen's Offense
Rashee Rice

Chiefs Have No Plans to Sign Rashee Rice to Long-Term Extension
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Cole Payton

Dynasty Managers Will Have to be Patient with Cole Payton
Taylen Green

Does Taylen Green's Speed Get Him on the Dynasty Radar?
Jack Endries

Is Jack Endries the Tight End of the Future in Cincinnati?
CJ Daniels

a Developmental Stash in Dynasty Leagues
Garrett Nussmeier

a Low-Risk Target with Upside in Dynasty Leagues?
Jam Miller

Has Sneaky Value if He Can Earn a Roster Spot
Justice Hill

a Dynasty Drop Candidate Wherever He's Still Rostered
J'Mari Taylor

Is J'Mari Taylor Worth a Taxi-Squad Spot in Deep Dynasty Leagues?
Greg Dulcich

Has a Lack of Competition Made Greg Dulcich a Dynasty Sleeper?
Carson Beck

a Worthy Investment in the Later Rounds of Rookie Drafts
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
De'Aaron Fox

Records Double-Double as Spurs Even Series
Victor Wembanyama

Sets Tone Early as Spurs Force a Pivotal Game 5
Isaac Guerendo

Could be a Drop Candidate in Dynasty Leagues in 2026
Jayden Higgins

' Dynasty Arrow is Pointing Up With Clear Path to WR2 Role in Houston
Jakobi Meyers

a Sell-High Candidate in Dynasty Formats?
Drake Maye

to Make a Big Leap in 2026 in Second Season With Josh McDaniels?
Jamal Murray

Earns First Career All-NBA Selection
Kevin Durant

Becomes First Player to Make All-NBA Team With Five Franchises
Shai Gilgeous-Alexander

Victor Wembanyama Lead All-NBA First Team
Taylor Hall

Enjoying Life in Carolina
Mark Stone

Returns to Action Sunday
Cale Makar

Rejoins Avalanche Lineup Sunday
Cason Wallace

Joins Starting Unit Sunday
De'Aaron Fox

Doesn't "Feel Great" Entering Game 4
Jalen Williams

Won't Play Sunday
Christian Watson

Is Christian Watson on the Verge of a Legitimate Breakout?
Khalil Shakir

Dynasty Value in Decline
Travis Hunter

Still a Risky Buy, Even at his Sunken Dynasty Cost
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
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Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
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Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
Evan Mobley

Tallies Series-High 24 Points on Saturday
Donovan Mitchell

Struggles at the Line Saturday
Karl-Anthony Towns

Continues Playmaking Surge on Saturday
OG Anunoby

Delivers Clean Shooting Line Saturday
Mikal Bridges

Fills Box Score in Game 3 Win
Jalen Brunson

Pushes Knicks Closer to NBA Finals
Orlando Magic

Magic Interview Jeff Van Gundy for Head-Coaching Position
Phillip Danault

Extends Point Streak to Three Games
Josh Anderson

Nets Two Goals in Painful Loss
Jalen Chatfield

Delivers Two Assists in Crucial Win
Mark Jankowski

Contributes Two Assists in Game 2 Victory
Eric Robinson

Scores in Second Consecutive Game
Nikolaj Ehlers

Tallies Two Goals as Hurricanes Bounce Back Saturday
Giannis Antetokounmpo

Magic Reportedly Have Giannis Antetokounmpo on Their Radar
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Nazem Kadri

Contributes an Assist in Losing Effort
Ross Colton

Nets Lone Avalanche Goal Friday Night
Rasmus Andersson

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Mickey Moniak

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Jackson Merrill

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Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
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Notre Dame-Stanford Rivalry Renewed Through 2028
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Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF