October 9, 2025
Dallas Cowboys wide receiver
CeeDee Lamb (ankle) missed another day of practice this week on Thursday. Lamb has made progress from a high-ankle sprain that has kept him sidelined for each of the last two games, but he's not on track to make his return in Week 6 against the Carolina Panthers. Per Joe Hoyt of The Dallas Morning News, the 26-year-old Pro Bowler continues to focus on conditioning and resistance training before he can think about getting back on the field. Lamb has not officially been ruled out for the weekend in Carolina, but that is likely coming on Friday. Fantasy managers can only hope that Lamb will make more progress next week and return to face the division-rival Washington Commanders in Week 7.
George Pickens will continue to operate as the WR1 in Dallas if Lamb misses another game, with tight end
Jake Ferguson also seeing a heavy target share.
Jalen Tolbert and
Ryan Flournoy will battle for the WR2 role if
KaVontae Turpin (foot) misses a second straight game.
--Keith HernandezSource: DallasCowboys.com
October 9, 2025
Las Vegas Raiders tight end
Brock Bowers (knee) is missing his fourth straight practice on Thursday, according to Ryan McFadden of ESPN. "We're hopeful we'll get Brock back soon. He's working his tail off in the rehab process, so we'll see how that goes," said offensive coordinator Chip Kelly. Bowers missed practice last Thursday and Friday before missing his first game of his career in the Week 5 blowout loss to the Indianapolis Colts. With two straight DNPs to begin this week, it's looking likely that the second-year tight end will miss a second straight contest this Sunday against the Tennessee Titans, unless he's able to practice on Friday. The 22-year-old's injury stems from when he injured his knee back in Week 1. The good news for the Raiders is that if Bowers sits out in Week 6, they should be getting
Michael Mayer back after he cleared the NFL's concussion protocol this week. Mayer could be worth TE2 streaming consideration in deeper leagues if Bowers is inactive again.
--Keith HernandezSource: ESPN.com - Ryan McFadden
October 9, 2025
San Francisco 49ers quarterback
Mac Jones (knee, oblique) was in uniform again for Thursday's practice, but he didn't do much throwing during individual periods in the early portion that was open to the media, according to Nick Wagoner of ESPN. Wagoner added that Jones really didn't do anything behind soft tossing on Thursday. The 27-year-old came out of last Thursday night's upset win over the Los Angeles Rams pretty banged up, but the Niners think he should be OK to make a fourth start in Week 6 against the Tampa Bay Buccaneers.
Brock Purdy (toe) has yet to practice this week and looks to be on track to miss his fourth game of the year after aggravating his turf-toe injury in Week 4. Jones will likely be listed as limited in practice for the second straight day, but he should be good to go this weekend. Fantasy managers shouldn't expect an encore against Tampa after Jones cooked against L.A.'s defense in Week 5.
--Keith HernandezSource: ESPN.com - Nick Wagoner
October 9, 2025
San Francisco 49ers wide receiver
Jauan Jennings (ankle, ribs) was in uniform and taking part on Thursday in the portion of practice open to the media, according to Nick Wagoner of ESPN. Head coach Kyle Shanahan said before Thursday's practice that Jennings might be limited on Thursday before returning to play on Sunday against the Tampa Bay Buccaneers in Week 6. Jennings did not play in last Thursday night's win over the Los Angeles Rams and didn't take part in practice on Wednesday. The 28-year-old's status for this weekend is still up in the air, but he appears closer to playing against the Bucs than fellow wideout
Ricky Pearsall (knee), who hasn't practiced at all this week. If Jennings is active in Week 6, he figures to operate as San Fran's No. 1 wideout, assuming he's not limited at all by his injuries. However, Jennings could be taking passes from backup quarterback
Mac Jones again, which would make him an even more shaky flex play in fantasy.
--Keith HernandezSource: ESPN.com - Nick Wagoner
October 9, 2025
San Francisco 49ers wide receiver
Ricky Pearsall (knee) did not practice with the rest of the team for the second straight day this week on Thursday, according to Cam Inman of the Bay Area News Group. Instead, Pearsall was doing conditioning on a side field with a support sleeve on his right leg. The 25-year-old second-year pass-catcher suffered a PCL injury in the Week 4 loss to the Jacksonville Jaguars and was held out of the Week 5 win over the Los Angeles Rams last Thursday night. He has not given up hope yet of playing this Sunday against the Tampa Bay Buccaneers, but it's not looking good for his chances right now. The Niners also were without
Jauan Jennings (ankle, ribs) a week ago, which led to
Kendrick Bourne having a career day as quarterback
Mac Jones' top target. Jennings has a better shot at returning this weekend, but if Pearsall misses another game, Bourne could be in line for another big day.
--Keith HernandezSource: Bay Area News Group - Cam Inman
October 9, 2025
For the second straight day of practice this week, San Francisco 49ers quarterback
Brock Purdy (toe) did not practice with the rest of the team, according to Cam Inman of the Bay Area News Group. However, Purdy was seen doing conditioning on a side field in cleats. While it's good to see Purdy doing something on a side field, a second straight DNP this week is making it likely that he is going to miss a second straight game and fourth of the season after aggravating his turf-toe injury in his return in Week 4. Fantasy managers shouldn't expect the 25-year-old to play in Week 6 against the Tampa Bay Buccaneers, and it's possible he won't be ready for Week 7 against the Atlanta Falcons, either.
Mac Jones (knee) has been playing at less than 100%, but he torched the Rams' defense in a win last Thursday night and looks set for his fourth start of the year on Sunday.
--Keith HernandezSource: Bay Area News Group - Cam Inman
October 9, 2025
Detroit Lions wide receiver
Amon-Ra St. Brown (wrist) practiced in full on Thursday after missing the team's Wednesday practice due to a wrist injury. The 25-year-old appears to be trending towards being available to play in Week 6 against the Kansas City Chiefs. St. Brown is the unquestioned number one option in the passing game for Detroit with 35 catches for 407 yards and six touchdowns on 41 targets through five games this season. If things were to reverse course and St. Brown were to miss time, Lions wideouts
Jameson Williams and
Isaac TeSlaa would likely see an uptick in target share, as would tight end
Sam LaPorta and running back
Jahmyr Gibbs. Assuming St. Brown can play on Sunday, he profiles as a must-start fantasy wide receiver in Week 6 against Kansas City.
--Will BradySource: Detroit Lions
October 9, 2025
Indianapolis Colts wide receiver
Alec Pierce (concussion) practiced in full for the second straight day on Thursday. Pierce has missed each of the Colts' last two games due to a concussion, but it appears he's trending towards returning in Week 6 against the Arizona Cardinals. The 25-year-old has recorded nine catches for 171 yards on 13 targets in three games so far this season. If he were to miss additional time, Colts wideouts
Ashton Dulin and
Adonai Mitchell would likely see the majority of the team's WR3 snaps alongside
Michael Pittman Jr. and
Josh Downs. Assuming Pierce is good to go in Week 6, he profiles as a desperation boom/bust flex option for fantasy managers against Arizona.
--Will BradySource: Indianapolis Colts
October 9, 2025
Pittsburgh Steelers running back
Jaylen Warren (knee) practiced in full for the second straight day on Thursday. The 26-year-old missed Pittsburgh's Week 4 matchup against the Minnesota Vikings due to a knee injury, but it appears the team's Week 5 bye served him well. The Steelers are currently prepping for a Week 6 matchup against the Cleveland Browns. Warren has recorded 274 yards from scrimmage and a touchdown on 54 total touches in three games this season. In Warren's absence in Week 4, Steelers running back
Kenneth Gainwell had a monster game, scoring two touchdowns and recording 134 scrimmage yards. Gainwell's performance may lead to him stealing some touches away from Warren once Warren returns. If he's able to play, Warren profiles as a low-end RB2/high-end flex option for fantasy managers in Week 6 against Cleveland.
--Will BradySource: ESPN - Brooke Pryor
October 9, 2025
Pittsburgh Steelers wide receiver
Calvin Austin III (shoulder) did not practice for the second straight day on Thursday due to a shoulder injury. Austin III suffered the injury in Week 4, so it's not a great sign that it's still keeping him out of practice with Pittsburgh coming off a Week 5 bye. The 26-year-old has recorded 10 catches for 139 yards and two touchdowns on 17 targets in four games so far this season. If Austin III is unable to play in Week 6 against the Cleveland Browns, Steelers wideouts
Roman Wilson,
Ben Skowronek, and
Scotty Miller could all see an uptick in snaps. However, the only Steelers wide receiver that should be on the radar of fantasy managers in Week 6 against Cleveland remains
DK Metcalf.
--Will BradySource: ESPN - Brooke Pryor
October 9, 2025
Buffalo Bills tight end
Dalton Kincaid (oblique) was officially listed as limited on the team's Thursday injury report due to an oblique injury. The Bills will play the Atlanta Falcons in Week 6 on Monday night, so Kincaid has an extra day to recover this week. The 25-year-old has recorded 20 catches for 287 yards and three touchdowns on 24 targets through five games this season. If he were to miss time, Bills tight ends
Dawson Knox and
Jackson Hawes would both likely see an uptick in snaps. Assuming Kincaid can play on Monday, he profiles as a solid fantasy TE1 in Week 6 against Atlanta.
--Will BradySource: Buffalo Bills PR
October 9, 2025
New Orleans Saints running back
Alvin Kamara (ankle) was back at practice on Thursday after suffering an ankle injury during the team's practice on Wednesday, according to ESPN's Katherine Terrell. Kamara was officially listed on the Wednesday injury report as limited, but it appears he's trending towards being fine for the team's Week 6 matchup against the New England Patriots. Kamara has recorded 360 yards from scrimmage and a touchdown on 90 total touches through five games this season. If he were to miss any time, Saints running back
Kendre Miller would likely dominate backfield touches in New Orleans. Assuming Kamara will be good to go on Sunday, he profiles as a low-end fantasy RB2 in Week 6 against New England.
UPDATE: Kamara was limited in practice again on Thursday.--Will BradySource: ESPN - Katherine Terrell
October 9, 2025
New Orleans Saints head coach Kellen Moore said that tight end/quarterback
Taysom Hill has "been taking reps" at quarterback and is "definitely available to be a backup quarterback" to Saints starter
Spencer Rattler. Hill famously played quarterback in college and started nine games under center for New Orleans across the 2020 and 2021 seasons. The 35-year-old completed a 19-yard pass in Week 5, his first game of 2025 after being activated off the physically unable to perform list. Hill is officially third on the Saints quarterback depth chart behind Rattler and rookie
Tyler Shough. Most likely, Hill will see most of his touches as a rusher and receiver in a gadget role. Still, any significant playing time at quarterback would make Hill a must-start player in fantasy, as he would likely still be eligible at the tight end position in most league formats.
--Will BradySource: ESPN - Katherine Terrell
October 9, 2025
Carolina Panthers tight end
Ja'Tavion Sanders (ankle) was a full participant in Thursday's practice, according to Joe Person of The Athletic. It was an upgrade over his practice status on Wednesday, when he was listed as limited. The 22-year-old has missed the last two games due to a right high-ankle sprain, but his full participation on Thursday suggests that he's trending toward a return on Sunday against the visiting Dallas Cowboys in Week 6. A Sanders return would mean no more TE2 streaming appeal for
Tommy Tremble in deeper leagues. When healthy, Sanders is Carolina's top pass-catching option at tight end, but that has not made him a top-10 fantasy option at the position. In three games before his ankle injury, he had just 11 receptions for 92 yards and no touchdowns on 14 targets.
--Keith HernandezSource: The Athletic - Joe Person
October 9, 2025
Carolina Panthers wide receiver
Jalen Coker (quadriceps), who is still on Injured Reserve, practiced in full on Thursday for the second straight day this week, according to Joe Person of The Athletic. Carolina opened Coker's 21-day practice window this week, and it's looking more likely that the second-year pass-catcher might be activated to make his season debut in Week 6 against the Dallas Cowboys. We probably won't know until Saturday if Coker will be activated from IR. The 23-year-old has made good strides since suffering his quad injury on Aug. 28, but the Panthers could elect to play it safe and give him another week of practice before potentially debuting in Week 7 against the New York Jets. Coker showed late last year in his first NFL season that he has the skills to take on a big role in Carolina's passing attack, and he could settle into the WR2 role in 2025 if he can stay healthy.
--Keith HernandezSource: The Athletic - Joe Person
RADIO
