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Oct 4, 2026, 2:18 PM ET

Philadelphia Eagles running back Saquon Barkley (hamstring) has been ruled out for the rest of Sunday's game against the Los Angeles Rams, according to Adam Schefter. Barkley pulled up after a six-yard run in the first quarter and grabbed at his right hamstring before heading to the medical tent. He later went to the locker room and was initially listed as questionable to return. Barkley finishes with two carries for eight yards. Tank Bigsby was the first back onto the field after Barkley left, with Will Shipley also available behind him. Philadelphia has not provided any further information yet on the severity of Barkley's hamstring injury.--Bruno Mulé
Source: Adam Schefter
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Oct 4, 2026, 2:11 PM ET

Washington Commanders quarterback Jayden Daniels (left elbow) will be a full participant in practice this week, head coach Dan Quinn said Sunday. Daniels was limited in all three practices last week before Washington ruled him out against the Indianapolis Colts. He has missed two straight games since dislocating his left elbow in Week 2 against Dallas. A full week of practice would put Daniels on track to return Sunday against the New York Giants, although he still needs to get through the week before Washington clears him to play. The timing could be important for the Commanders after Marcus Mariota aggravated his right MCL against Indianapolis and is expected to miss some time.--Bruno Mulé
Source: Tashan Reed
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Oct 4, 2026, 2:08 PM ET

Green Bay Packers running back Chris Brooks (ankle) is questionable to return in a Week 4 matchup against the Tampa Bay Buccaneers due to an ankle injury, according to the team. Brooks was injured in the second quarter. He was leading the Packers with four carries for 30 rushing yards (7.5 yards per carry) at the time of his exit. He also had one reception for five yards. Running backs MarShawn Lloyd and Kaleb Johnson will fill in for Green Bay's backfield while Brooks is out.--Ryan O'Bleness
Source: Green Bay Packers
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Oct 4, 2026, 1:58 PM ET

Cincinnati Bengals wide receiver Ja'Marr Chase (concussion) is being evaluated for a concussion and is questionable to return, according to the team. He was seen entering the blue medical tent in a Week 4 matchup with the Jacksonville Jaguars, according to Charlie Goldsmith of the Charlie's Chalkboard newsletter and FOX19. The injury occurred after Chase caught a four-yard pass and Jacksonville cornerback Jarrian Jones was called for a face mask penalty. Other wide receivers for the Bengals include Tee Higgins, Dohnte Meyers and Mitch Tinsley.--Ryan O'Bleness
Source: Cincinnati Bengals
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Oct 4, 2026, 1:46 PM ET

Washington Commanders wide receiver and returner Jaylin Lane is dealing with a serious ankle injury, according to head coach Dan Quinn, as reported by JP Finlay of NBC4 Sports Washington. Lane was injured on a kickoff return early in the third quarter of a Week 4 loss to the Indianapolis Colts in London. He did not appear to be able to put any pressure on his left leg and had to be carted off of the field. Lane was quickly ruled out of the game and did not return. Lane did not record any receptions and had three kickoff returns for 80 yards (26.7 yards per return) against the Colts. He has tallied two receptions for 25 yards (12.5 yards per attempt) in 2026.--Ryan O'Bleness
Source: JP Finlay - NBC4 Sports Washington
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Oct 4, 2026, 1:24 PM ET

Philadelphia Eagles running back Saquon Barkley (hamstring) is questionable to return against the Los Angeles Rams due to a hamstring injury, according to the team. He was seen hobbling after a six-yard run against the Los Angeles Rams in Week 4, according to Zach Berman of The Athletic. Following the run, Barkley was spotted limping on the sideline and then went to the blue medical tent. Running back Tank Bigsby has entered the lineup in Barkley's absence. Will Shipley is also available in the backfield for the Eagles.--Ryan O'Bleness
Source: Philadelphia Eagles
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Oct 4, 2026, 1:08 PM ET

Free-agent running back Joe Mixon is visiting the Seattle Seahawks, according to Jay Glazer on FOX. Mixon has not played since 2024 after a foot injury wiped out his entire 2025 season, but he was still productive the last time he was on the field. He rushed for 1,016 yards and 11 touchdowns on 245 carries in 14 games for Houston while adding 36 catches for 309 yards and another score. Seattle has a reason to look for help. Rookie Jadarian Price (chest) was placed on injured reserve Saturday and must miss at least four games. Zach Charbonnet (knee) returned to practice this week but cannot be activated until Week 5 at the earliest as he works back from a torn ACL. Emanuel Wilson and George Holani are among the backs currently available. Mixon is only visiting at this point, so there is no guarantee he signs, but his past production and Seattle's short-term uncertainty make him a reasonable speculative stash in deeper fantasy leagues.--Bruno Mulé
Source: Lauren Helmbrecht
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Oct 4, 2026, 12:40 PM ET

Washington Commanders quarterback Marcus Mariota (right knee) aggravated the MCL injury he first suffered during the preseason and is expected to miss some time, according to Ian Rapoport. Mariota will undergo additional testing after leaving Sunday's game against the Indianapolis Colts in the first quarter. He completed three of four passes for 46 yards and added a 35-yard run before going down. Rapoport also reported that there is hope Jayden Daniels (left elbow) can return in Week 5 against the New York Giants. Daniels was limited in all three practices this past week but was ruled out Friday, with Washington planning to reevaluate him after another week of work. If Daniels is not ready, rookie Athan Kaliakmanis would be next in line with Mariota now expected to miss time.--Bruno Mulé
Source: Ian Rapoport
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Oct 4, 2026, 12:26 PM ET

San Francisco 49ers wide receiver Mike Evans (ribs) will play Sunday against the Denver Broncos despite dealing with fractured ribs, according to FOX Sports' Jay Glazer. Evans will wear protective covering over the injured area during the game. He did not practice Wednesday or Thursday before returning for a limited session Friday, and the 49ers listed him as questionable coming into the weekend. Evans has 12 catches for 137 yards and two touchdowns through three games. He'll give it a go against Denver, though how much the rib injury affects him once the game starts remains to be seen.--Bruno Mulé
Source: FOX Sports
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Oct 4, 2026, 12:18 PM ET

Las Vegas Raiders tight end Brock Bowers (illness) has been added to the injury report, but his status for Week 4 against the Kansas City Chiefs remains unchanged, according to Sam Warren of The Athletic. Bowers will play against the Chiefs on Sunday. This injury report update from the organization was merely procedural, as the Raiders are required to report any injuries or illnesses that are impacting their players. Barring a setback, Bowers should operate at full strength as the Raiders look to improve to an unimaginable 4-0 record. The 23-year-old tight end was quite impressive in his season debut last week, catching 10 passes for 116 yards and one touchdown. He wasted no time developing a strong rapport with Kirk Cousins, and he should remain a high-end TE1 in fantasy football for Week 4.--Andersen Pickard
Source: Sam Warren
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Oct 4, 2026, 12:08 PM ET

Philadelphia Eagles right tackle Lane Johnson is inactive for Sunday's Week 4 game against the Los Angeles Rams due to personal reasons, according to Ian Rapoport. Johnson was added to the game-status report Sunday morning as questionable after carrying no designation coming out of the practice week. The Eagles are also without backup tackle Fred Johnson (knee) for the second straight game, so rookie Markel Bell is set to make his first NFL start at right tackle. It is a notable change up front for an offense built around Jalen Hurts and Saquon Barkley, with Philadelphia suddenly turning to an inexperienced option on the right side of the line.--Bruno Mulé
Source: Ian Rapoport
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Oct 4, 2026, 11:56 AM ET

Tennessee Titans running back Tyjae Spears (ankle) is officially active for Sunday's Week 4 contest against the Baltimore Ravens. He had been listed as questionable but was trending in the right direction after logging a full practice on Friday. The 25-year-old has been off the fantasy radar almost entirely this year due to the state of the Titans' offense and his role behind Tony Pollard. Through three games, Spears ranks as the overall RB49 in PPR leagues with 58 rushing yards and 41 receiving yards. Even his receiving contributions seem to have been scaled back, as he has been limited to a modest (by his standards) four catches on six targets this season. He should still be rostered in 12+ team leagues, but there's no reason to start him in fantasy lineups at this point.--Andersen Pickard
Source: Jim Wyatt
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Oct 4, 2026, 11:55 AM ET

Los Angeles Rams tight end Colby Parkinson (knee/shoulder) is inactive for Sunday's Week 4 game against the Philadelphia Eagles, according to Nate Atkins. Parkinson did not practice Wednesday, Thursday, or Friday and entered the weekend listed as questionable. He has caught three passes for 21 yards through the first three games of the season. Los Angeles is also without Terrance Ferguson (ankle), leaving the Rams down two tight ends against Philadelphia. Tyler Higbee, Davis Allen, and rookie Max Klare are available to handle the work at the position with Parkinson and Ferguson sidelined.--Bruno Mulé
Source: Nate Atkins
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Oct 4, 2026, 11:54 AM ET

Baltimore Ravens wide receiver Zay Flowers (hamstring) is officially active for Sunday's Week 4 contest against the Tennessee Titans. Flowers logged a full practice on Thursday and a limited practice on Friday, and he ultimately entered this weekend listed as questionable. In the end, not only will he play, but he's also expected to operate without any sort of limitations, according to a previous report from Jeremy Fowler of ESPN.com. Barring a setback or new injury, this will be Flowers' first game of the season with a snap share of at least 35%. In Week 1, he exited in the first half due to a quad injury, although not before racking up 150 yards and a touchdown. He did play in Week 3, but he remained on a snap count in his first game back from injury. Now that he doesn't have any limitations, Flowers should return to his WR1 form in fantasy football, especially against a suspect Titans defense.--Andersen Pickard
Source: Jeff Zrebiec
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Oct 4, 2026, 11:51 AM ET

New England Patriots tight end Eli Raridon (thigh) is officially active for Sunday's Week 4 contest against the Buffalo Bills. He had been listed as questionable after practicing in a limited capacity all week long. The rookie has two catches for 32 yards and one touchdown through two games this season. He has consistently operated behind Hunter Henry, and neither tight end has emerged as a worthwhile starter in fantasy football. This is not the week to bank on a Raridon breakout; the Bills have surrendered the ninth-fewest receiving yards and the ninth-fewest fantasy points to opposing tight ends through the first three weeks of the 2026 season.--Andersen Pickard
Source: New England Patriots

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