👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Chargers vs Chiefs Start 'Em, Sit 'Em: Mike Williams, Juju Smith-Schuster, Austin Ekeler, Josh Palmer, Isiah Pacheco, Gerald Everett

Patrick Mahomes - Fantasy Football Rankings, DFS Lineup Picks, NFL Injury News

Fantasy football start em, sit em and lineups advice for the Chargers vs Chiefs Thursday Night game in Week 2 (2022). TNF matchups analysis with detailed breakdowns.

Welcome to Week 2! Last week, we went 2-0 with our picks against the spread and on the over/under. Let’s not slow down as we head into arguably the best matchup of the week for fantasy football fans.

After shaking off the remaining ghosts from last season, Justin Herbert and company head over to Arrowhead. With many of the favorites struggling to find success in Week 1, Patrick Mahomes handily took care of business. And by handily, I mean the poster boy of the NFL embarrassed the Cardinals for five touchdowns and 360 yards. Meanwhile, Herbert held his own, completing 26 of 34 attempts for 280 yards and three touchdowns against the division rival Raiders. Commonly listed alongside each other as the best QBs in the league, this will be a delight to watch.

However, this matchup is a lot more than the QBs. This also might be an interesting matchup with a lot of fourth-down gambles as the Chiefs are missing Harrison Butker and the Chargers have head coach Brandon Staley. With fantasy stars all around, there is no shortage of content for this article. Thank you for joining me again this week. Once again, my name is Ellis Johnson, and this is your RotoBaller Thursday Night Football Preview.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Los Angeles Chargers @ Kansas City Chiefs - 8:20 pm ET 

Notable Injuries:

 

Must-Starts for Fantasy Football Lineups

Justin Herbert (QB, LAC)

This is a slam dunk. As mentioned above, he is coming off a very successful Week 1 performance, which pairs nicely with his QB2 finish in 2021. Herbert is a star, and if he manages to string together some playoff wins, he could very well challenge Mahomes and Allen for the best QB in football. 

Going to Arrowhead typically strikes fear in the hearts of fantasy players. Although it can always be high scoring, this stadium is intimidating. Well, at least it’s intimidating for some. In Herbert’s two career games in KC, he has thrived under the bright lights, passing for seven touchdowns, zero interceptions, and 583 yards. There is no reason to shy away from the young gun-slinger, and he’s my QB1 for this week.

Patrick Mahomes (QB, KC)

After what Mahomes did last week, saying Herbert is my QB1 right before talking about Mahomes might be a little disrespectful. After all, he just torched the Cardinals on the road for five touchdowns and over 350 yards. Although the Cardinals' defense is not nearly the same as this Chargers team who was all over Derek Carr in Week 1.

With the additions of J.C Jackson and Khalil Mack to put alongside Joey Bosa, this team is a threat to any QB. In fact, Mack managed to rack up three sacks in his debut last week. On the other hand, this is the Chiefs we’re talking about. Even without Tyreek Hill, Mahomes didn’t miss a beat. Don't worry, he’s a top option this week as well.

Travis Kelce (TE, KC)

He’s the best tight end in fantasy. All this offseason love for Mark Andrews was cute while it lasted, but we all know who’s on top. Even at 33, Kelce is a monster. No disrespect to Mark Andrews, but Lamar isn’t quite Mahomes, and the Ravens aren’t nearly the passing attack of the Chiefs. 

Kelce is the clear top option on one of the league's best offenses. In last week’s blowout, Kelce caught eight of nine targets for over 120 yards and a score. If Mahomes needs a play, it’s no surprise who the ball is going to. Many of these Chargers might still be haunted by when Kelce caught that spectacular long touchdown to win the game in overtime last year. My guess is these fears won’t be settled on Thursday.

Austin Ekeler (RB, LAC)

You probably aren’t considering removing him from your lineup, but you’re probably not thrilled after last week. I’m hoping this will build your confidence and make you excited to play one of the nicest guys in fantasy football.

Last week, Ekeler was inefficient, rushing 14 times for 36 yards and catching all four targets for another 36 yards. This should be his absolute floor for the season. Not only is this game likely high scoring, but with Keenan Allen missing due to injury, this should increase Ekeler’s target share. Give me every bit of Ekeler in a high-scoring matchup with locked-in target volume - he’s a top-three play for me this week.

Mike Williams (WR, LAC)

Much like Ekeler, you most likely aren’t considering benching Mike Williams, but you can’t be thrilled after last week. Despite being one of the most popular breakout picks all offseason, Williams managed to pull a classic disappearing act. Catching only two of four targets for 10 yards was a little worrisome.

Thankfully, we have seen this before with Williams and he has managed to bounce back. Plus, without Allen, Herbert will have to rely on him as a top target. Williams, much like Herbert,  has a history of success in arrowhead as well as a history of haunting the Chiefs when Allen has missed. Over the last two years, he has combined for 230 yards and three touchdowns in his two games in KC. He’s a top-10 play for me this week, and I suspect there’ll be some jaw-dropping catches on the way.

Clyde Edwards-Helaire (RB, KC)

Why not continue to spread the love and tell you why CEH is a must-start? Despite starting his career in an underwhelming fashion for fantasy, CEH was always a decent runner. However, more importantly, he is a great pass catcher. 

In the offseason, I wrote about the dismissal of Hill’s departure impacting the running back position. Particularly, it’s well known that when a top WR leaves, the targets typically increase for the RB the following year. Plus, Darrell Williams managed an excellent season in 2021 with 450 receiving yards and 47 receptions. Now that both Williams and Hill have left, CEH is in line for a resurgent season.

Thankfully, this all came true in Week 1. CEH was excellent, especially in the receiving game. Catching all three of his targets for 32 yards and two scores, he was the clear lead back for this offense. Although he only had seven carries, I think a lot of this was a result of the game getting out of hand quickly. I can’t imagine the Chargers don’t hang, if not lead this game, making CEH set up for another big week.

 

Solid Starts for Fantasy Football Lineups

Gerald Everett (TE, LAC)

Considering the tight end landscape, I think Everett might be one of the better plays this week. In his debut with the Chargers, he caught three of four targets for 54 yards and a score. What was really interesting about this matchup is that the Chargers relied heavily on all of their tight ends. This is a little concerning as I can’t think of many things grosser than a tight end by committee, but I think they saw a mismatch specific to the Raiders. 

This matchup should be high flying and without Allen, Herbert might look Everett’s way more often. He is a great bet to score again this week, which makes him a solid start for Week 2.

 

Flex Considerations for Fantasy Football Lineups

Josh Palmer (WR, LAC)

I wanted to emphasize my belief in him and put him as a solid start, but he is most likely sliding into the flex spot on your team. I’m not saying you should go wild and play him as a top-24 option, but he is one of the better upside plays this week, specifically if Allen is not playing. 

Out of Brampton, Ontario, Palmer has been great to start his career. He was getting praised all off-season and entered the season as the clear third WR. Despite DeAndre Carter finding the endzone, each of Palmer, Carter, Williams, and Allen had four targets. Palmer has the talent, and trust of Herbert to have a very solid fantasy week in Week 2. In fact, I’ll bring back an old segment of mine and say the Pie Shop is open for Palmer this week. 

*Pie Shop: An Australian term (often used in Rugby League) to describe who will score a Try (or in this case touchdown) this week.

Marquez Valdes-Scantling and JuJu Smith-Schuster (WR, KC)

Considering the team scored over 40 points, I was a little disappointed in both of these players. It was nice to see Juju lead the receivers with eight targets, but he did lose a fumble. He should be the top WR, but I think the WRs on this team are cloudy at best. The other side of this is MVS, who caught all four of his targets for 44 yards. Interestingly, despite having fewer targets, MVS led all receivers in snaps. Both players had a solid debut on their new team, and aren’t bad flex plays this week. I would rank the three receivers in this section as Palmer, Juju, and MVS.

 

Consider Sitting for Fantasy Football Lineups

Isiah Pacheco (RB, KC)

Personally, I don’t want to play Pacheco. It is worth noticing that he did lead the team with 12 carries (five more than CEH), but almost all of his carries came in the fourth quarter in what many call, garbage time. He is the clear backup to CEH and will compete with Jerick McKinnon for looks. Although promising for dynasty managers, don’t get caught up in the hype in redraft leagues.

Mecole Hardman and DeAndre Carter (WR, KC and LAC)

I’m grouping these two together as both were depth plays that happened to score touchdowns last week. Before we get too excited, this week, I wouldn’t trust either. I think Hardman looked solid, but he is the clear fifth receiving option behind CEH, Kelce, Juju, and MVS. As for DeAndre Carter, he has had surprising fantasy relevance over the years, primarily with Washington. Although I prefer him to Hardman, he isn’t more than a salary cap filler in DFS.

Ellis’ Picks

Chargers +4.0 (1-0), Over 54.5 (1-0)

We started the year on fire hitting the Under and the Bills to cover the spread in Week 1. I hope to continue this trend in this week’s heavyweight tilt. I think these teams are quite evenly matched, and both performed well in their season openers. Not to take anything away from Mahomes and company, but I think some of it was on the Cardinals playing really poor defense.

The Chargers will no doubt struggle to slow down the Chiefs, but this defense looked great against the Raiders. Initially, I was thinking that the line is set a little high for a divisional match. However, without Butker on one side, and fourth-down gambler Brandon Staley on the other side, there might be a lot more touchdowns with very few field goals. 

Career record: Spread (23-14), Over/Under (22-15)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




REAL-TIME FANTASY NEWS

Tyjae Spears

has Limited Long-Term Upside in Dynasty Formats
Jaylen Wright

a Buy-Low Candidate as a Handcuff?
Ollie Gordon II

Dynasty Value Takes a Hit After Teammate's Extension
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
Micah Parsons

Expected to Miss the Early Part of the Season
Colby Parkinson

a Clear Dynasty Sell-High Candidate Entering 2026
Omarion Hampton

Poised for Year 2 Breakout in Los Angeles
Blake Corum

Dynasty Stock Rising After Encouraging 2025 Campaign
Jaxson Dart

Does Jaxson Dart Carry High-End Dynasty QB1 Upside?
David Montgomery

Dynasty Stock Rising Following Move to Houston
Chris Godwin Jr.

Can Chris Godwin Jr. Re-Establish His Dynasty Value in 2026?
Malik Willis

Not Set Up for Immediate Success in Miami
Terrance Ferguson

has Promising Receiving Skills in Crowded TE Room in L.A.
Brenton Strange

Is Brenton Strange a Top-15 Dynasty Tight End?
T.J. Watt

Steelers Ready to Move on From T.J. Watt?
Jacory Croskey-Merritt

Must Make Gains as Pass-Catcher to Take the Next Step
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Kaytron Allen

Could Kaytron Allen Take on a Big Role Right Away?
Demond Claiborne

Has Long-Term Appeal in Minnesota
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Adam Randall

to Contribute as a Pass-Catcher Right Away?
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Nicholas Singleton

Could Contribute Right Away
Bryce Lance

a Perfect Fit in New Orleans?
Mike Washington Jr.

Can Mike Washington Jr. Force a Backfield Split in Vegas?
Paul Reed

Makes Big Impact Off the Bench Wednesday
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Jarrett Allen

Records Double-Double in Game 5 Win
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF