X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

DraftKings, FanDuel Daily Fantasy Baseball Picks (9/21/22): Today's Top MLB DFS Lineups

Triston McKenzie fantasy baseball rankings draft sleepers MLB injury news

The top daily fantasy baseball lineup picks for FanDuel and DraftKings on September 21st, 2022. Juan Carlos Blanco's MLB DFS analysis and sleepers for building optimal DFS rosters.

Welcome back to another edition of the FREE DraftKings and FanDuel MLB DFS picks. As customary, we have an all-day ledger on tap Wednesday, and although DraftKings does not have a full-day slate, FanDuel does. Consequently, today's article will feature picks on both sites for games throughout the day, as even on DK, the suggestions will prove viable for someone playing one of the site's split slates.

We have an interesting pitching pool on Wednesday's slate, as there aren't a lot of clear-cut options to choose from. Additionally, some scenarios that would appear to be favorable matchups on the surface, such as Luis Severino's turn against the Pirates in the Bronx, carry an asterisk, as the right-hander could be on a pitch count in his first start off the 60-day IL. However, there are three options I'm confident in, as well as a solid selection of hitters we can target the numerous questionable arms that are taking the hill with.

This article will provide my daily fantasy baseball lineup picks for FanDuel and DraftKings on 9/21/2022 that includes a FanDuel main slate locking at 12:20 pm ET. The lineup will range from some elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for other sports. It's also essential to monitor injury news and today's MLB starting lineups. If you have any questions or comments, find me on Twitter and ask away!

Featured Promo! Save 30% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

DraftKings, FanDuel Pitchers - MLB DFS Lineup Picks

Triston McKenzie - CLE at CWS ($10,100 DK, $9,600 FD)

McKenzie may only have a 10-11 record, but it's accompanied by an impressive 3.08 ERA, 0.97 WHIP, and solid 8.7 K/9. The big right-hander has really hit his stride down the stretch as well, pitching to a 2.41 ERA, 0.92 WHIP, 9.3 K/9, and improved 1.0 HR/9 over the 52.1 innings covering his last eight starts. That sample includes a gem of a quality start against the White Sox on Aug. 19th where he struck out 14 over seven frames.

McKenzie had also been very effective against Chicago in two prior starts this season, allowing just two runs over 10 innings in that pair of outings. Current ChiSox bats only have a collective .217 average and .611 OPS against McKenzie in 117 career encounters as well, and the White Sox, despite their abundance of big names, have just a middling .316 wOBA and .159 ISO against right-handed pitching in September.

Robbie Ray - SEA at OAK ($9,600 DK, $10,000 FD)

Ray has had his share of troubles on the road and comes into Wednesday's start with back-to-back rocky starts against the Braves and Angels. However, the southpaw has a favorable matchup in a pitcher's park against a team he's already enjoyed success against on multiple occasions this season, making him worthy of consideration in both cash games and tournaments as he aims for a bounce-back performance.

Ray has pitched to a 2.41 ERA across 18.2 innings in three starts against Oakland this season, and current A's bats own a collective .163 average and .466 OPS against him in 50 career plate appearances, a sample in which Ray has compiled 20 strikeouts. Oakland has also been the AL's worst team against left-handed pitching at home in the second half of the season, producing a .214 average, .604 OPS, .264 wOBA, and -9.1 wRAA in a sample of 260 plate appearances. The A's even have just a 5.8 percent walk rate in that split, which helps guard against Ray's occasional control issues.

Other options: Miles Mikolas - STL at SDP ($9,100 DK, $8,800 FD)

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms, where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's Jon Anderson on DraftKings - join in on the winning!

 

DraftKings, FanDuel Infielders - MLB DFS Lineup Picks

Matt Olson - 1B, ATL vs. Josiah Gray ($4,900 DK, $3,000 FD)

Olson entered Tuesday's action with a whopping 70 extra-base hits, including 28 homers, and 91 RBI in his first season for the defending champions. While a high strikeout rate is part of the package with Olson, deploying his powerful left-handed swing against a right-hander in Gray who's been absolutely incapable of keeping the ball in the park certainly makes sense, especially at very reasonable salaries on both sites.

Olson has slugged 22 of his 28 round trippers off right-handed pitching, and he owns a .339 wOBA and .234 ISO against that handedness at home. Meanwhile, Gray has given up a jaw-dropping 37 home runs across 136.2 innings. He's allowed 22 of those to left-handed hitters, which have tagged him for a .268 average, .987 OPS, and .417 wOBA, along with a 21.6 percent HR/FB rate.

Jeff McNeil - 2B, NYM at Adrian Houser ($4,200 DK, $2,900 FD)

Houser hasn't been anywhere near as effective as during his career-best 10-6 season in 2021, generating a 6-9 mark, 4.85 ERA, and 1.49 WHIP across 94.2 innings. The veteran right-hander has been better at home, but he's still enduring his usual struggles against left-handed bats; the highly reliable McNeil, who entered Tuesday with a .320 average and .822 OPS, therefore makes for an excellent option to deploy against him.

Houser has given up a .313 average and .379 wOBA to left-handed hitters overall, and although he's had more trouble against them on the road, he still carries a bloated 5.89 BB/9 and 4.76 xFIP against them at home. Then, McNeil has been at his best when facing right-handed pitching on the road, where he owns a .341 average, .880 OPS, and .380 wOBA against that handedness.

He also went into Tuesday's action with a .328 average and .359 wOBA in 80 plate appearances across 18 September games. Then, the matchup remains favorable for McNeil when Houser exits, as Milwaukee relievers have pitched to a .278 BAA and .351 wOBA against lefty bats in September.

Trea Turner - SS, LAD vs. Madison Bumgarner ($5,600 DK, $4,100 FD)

Turner is in the midst of yet another MVP-caliber season, entering Tuesday with a .304 average, .829 OPS, 20 homers, 97 RBI, and 25 steals. The veteran shortstop has been very effective against either handedness of pitcher as those numbers imply, but he's been at his best versus southpaws and faces an aging, struggling one in Bumgarner. MadBum's last double-digit win season came in 2016, and he enters Wednesday's start with a career-high 15 losses along with a 5.01 ERA and 1.48 WHIP.

Turner boasted a .329 average, .944 OPS, .404 wOBA, and .233 ISO against left-handed pitching at Dodger Stadium going into Tuesday night's action, as well as a .346 wOBA and modest 15.5 percent strikeout rate in 71 plate appearances in September. He's also been an outstanding clutch hitter all season with a .307 average with runners on base, including a .325 figure with men in scoring position, a trait that comes in especially handy in a star-studded lineup that offers so many RBI opportunities.

For his part, Bumgarner has been victimized by right-handed bats on the road for a .311 average, .386 wOBA, and 5.17 xFIP, while also surrendering an elevated 39.8 percent hard-contact rate in that split.

Josh Jung - 3B, TEX vs. Tucker Davidson ($2,200 DK, $3,100 FD)

Jung has been a bright spot overall during his brief time in the majors after a promising minor-league career, holding his own against big-league arms early with a respectable .250 average and impressive .800 OPS across his first 40 big-league plate appearances entering Tuesday.

The rookie has been particularly effective against left-handed pitching, continuing a trend he exhibited during his minors days at multiple stops, and he draws an appealing matchup against a southpaw in the favorable hitting environment of his home park Wednesday.

Jung went into Tuesday's game hitting .316 with a 1.053 OPS and .443 wOBA over his first 19 plate appearances versus lefties, a sample in which he'd quickly belted a pair of doubles and two homers on the strength of a 50.0 percent hard contact rate. Davidson seemingly makes for a good target to pick on, considering he's pitched to a .291 average and .353 wOBA against right-handed hitters, along with a 1.68 WHIP and 5.47 xFIP when facing them on the road.

Other options: Dansby Swanson - SS, ATL vs. Josiah Gray ($5,500 DK, $3,600 FD); Ryan McMahon - 3B, COL vs. SFG ($5,200 DK, $3,100 FD)

 

DraftKings, FanDuel Outfielders - MLB DFS Lineup Picks

Charlie Blackmon - COL vs. Logan Webb ($5,100 DK, $3,000 FD)

Blackmon is enjoying another impressive season in Colorado despite his club being a non-contender yet again. The veteran outfielder entered Tuesday's action with a solid .263 average, .734 OPS, 42 XBH, and 76 RBI. Blackmon is also thriving as usual in his home park, and he's facing a right-hander in Webb that he's enjoyed plenty of success against before and that's shown some vulnerability in a couple of recent starts.

Blackmon has tagged Webb for a .450 average with three doubles, a homer, and only three strikeouts in 23 career encounters, and he's teed off on right-handed pitching at Coors Field for a .803 OPS, .341 wOBA, and .221 ISO. Webb has allowed an elevated .282 average and .437 slugging percentage to the 73 batters he's faced thus far in September, including a .355 average, 1.020 OPS, and .432 wOBA to 32 lefty bats in that sample. Webb has allowed a .276 average and .344 wOBA to lefty hitters on the road this season overall, and the Coors Field environment only makes it a more dangerous scenario for him. Giants relievers also have a .341 wOBA against lefty hitters in September, furthering Blackmon's case.

Joc Pederson - SFG at German Marquez ($5,100 DK, $2,700 FD)

Pederson has put together quite the comeback season during his first year in San Francisco, taking a career-high .260 average into Tuesday night's action and complementing it with an excellent .841 OPS. The lefty-swinging slugger has slugged 13 of his 22 homers outside his pitcher-friendly home park, and Wednesday, he makes for an excellent way to gain access to Marquez at Coors and his vast struggles against left-handed hitters.

Marquez has yielded a .326 average, .397 wOBA, and 2.2 HR/9 to left-handed hitters at Coors Field, partly the byproduct of the fact he's conceded a 27.0 percent line-drive rate and 40.1 percent hard-contact rate in that split. Pederson is therefore a highly dangerous opponent for him, considering his prodigious power and the fact he's posted a .272 average, .903 OPS, and .380 wOBA versus right-handed pitching on the road, along with a 44.4 percent hard-contact rate.

Julio Rodriguez -  SEA at James Kaprielian ($5,500 DK, $4,100 FD)

Rodriguez jumped back into the lineup Tuesday night after missing three games with a tight lower back, so he should be good to go for this favorable matchup against Kaprielian. The AL Rookie of the Year frontrunner has already tormented the A's right-hander on numerous occasions in the past, posting a .500 average with two triples and a homer over 12 plate appearances without striking out once in that sample. Rodriguez also came into Tuesday's game on quite the tear, having generated a .447 average, five homers, and a 1.428 OPS over the previous 10 games.

Kaprielian has had plenty of positive moments this season, but he's still given up a .299 average, .407 wOBA, and .951 OPS to right-handed hitters at home, along with a 1.9 HR/9 and 6.19 xFIP. Rodriguez has thrived against right-handed pitching on the road as well, as evidenced by his .281 average, .825 OPS, and .357 wOBA in that split, as well as a 37.0 percent hard-contact rate.

Other options: Mike Yastrzemski - SFG at German Marquez ($4,200 DK, $3,100 FD); Mike Trout - LAA at Dane Dunning ($6,200 DK, $4,300 FD)

 

DraftKings, FanDuel MLB DFS Stacks

  • Braves vs. Josiah Gray, WAS, RHP
  • Rockies vs. Logan Webb, SFG, RHP
  • Giants at German Marquez, COL, RHP



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Joel Embiid

Likely Out Friday
Andrew Nembhard

is Ruled Out for Friday
Josh Giddey

Could Sit Again Friday
Pascal Siakam

is Probable for Friday's Game
Immanuel Quickley

to Miss Seventh Straight Game
Jock Landale

to be Re-Evaluated in Two Weeks
Kyshawn George

Won't Return This Season
Mark Williams

is Cleared to Return on Thursday
Anthony Edwards

Out Again Thursday
Konnor Griffin

Secures $140M Deal; Pittsburgh Building Around Young Star
Carter Yakemchuk

in Concussion Protocol
Quinten Post

Ruled Out on Thursday
NJ

Arseni Gritsyuk Done for the Season
Tyson Foerster

Available Against Red Wings
Luke Kornet

Slated to Suit Up Thursday
Zach Hyman

a Game-Time Decision Thursday
Bryan Rust

Will Play Thursday
Victor Wembanyama

Sidelined on Thursday
Carter Hart

Returns to Action Thursday
Aaron Ekblad

to Be Out for "Weeks" With Broken Finger
Cade Cunningham

Making Progress in Collapsed Lung Recovery
NFL

Emmett Johnson's NFL Ceiling in Question?
Ollie Gordon II

Dynasty Value Rising Amidst Organizational Changes in Miami?
Colby Parkinson

Faces Heavy Competition for Targets in Los Angeles
Rashee Rice

Legal Issues Limit His Dynasty Value
Omarion Hampton

Remains a High-End Dynasty Running Back Despite Injury-Marred Rookie Season
NFL

Germie Bernard Has the Versatility to Make Him an Early Contributor
NFL

Demond Claiborne Fighting Against Type with Unusual Archetype
Roman Hemby

Likely Little More Than a Fantasy Dart Throw
NFL

Can Bryce Lance Be the Next Small School Fantasy Gem?
NFL

Where Does Michael Trigg Fit into Crowded Tight End Class?
Tyler Shough

a Sneaky QB1 Option in 2026?
Blake Corum

Not Just a Handcuff Going Forward?
Jaxson Dart

Gets Top Receiver Back in New-Look System
Calvin Ridley

Comes Back to Uncertain Role
Kirk Cousins

Raiders Sign Kirk Cousins
Konnor Griffin

Being Promoted to MLB Roster Ahead of Friday's Contest
Karlo Matković

Karlo Matkovic Dealing With Back Issue, Questionable Thursday
Isaiah Jackson

Misses Third Straight Game
Jordan Goodwin

Ready to Face Hornets
Sam Merrill

Available Thursday
Alex Caruso

Questionable for Thursday Due to Illness
Isaiah Hartenstein

Cleared for Thursday's Action
Jalen Williams

Good to Go Thursday
Tony Pollard

Remains the Lead Back for Now
David Montgomery

Is David Montgomery Really the Bell Cow in Houston?
Chris Godwin Jr.

a Low-End WR2 After Teammate's Departure?
LeQuint Allen Jr.

to Get More Involved in Year 2?
Isaiah Davis

Faces Improbable Path to Fantasy Relevance
Michael Carter

Signing with the Titans
Jock Landale

Leaves Game with Ankle Injury
Brandon Hagel

Likely Out on Thursday
Damon Severson

Not Expected to Return During Regular Season
Igor Chernyshov

a Game-Time Call Wednesday
Radko Gudas

Out Wednesday
Cutter Gauthier

Questionable for Rest of the Week
Evander Kane

Unavailable Wednesday
Cale Makar

to Miss "Some Time"
Konnor Griffin

Pirates in "Deep" Negotiations for Long-Term Contract
Carlos Estévez

Royals Place Carlos Estevez on 15-Day Injured List
CFB

Gunner Stockton Looking "Great" After Offseason Injury
CFB

Sam Leavitt Showing "Encouraging Signs" at LSU Practice
J.J. Spaun

Needs the Putter to Cooperate in San Antonio
Thorbjorn Olesen

Trending Up in San Antonio
Denny McCarthy

Carrying Momentum into San Antonio
Matt Grzelcyk

Unavailable for Reminder of Season
Artyom Levshunov

Ruled Out for Rest of Season
Mathieu Olivier

to Miss Couple of Weeks
Evan Rodrigues

to Have Season-Ending Surgery
Sam Reinhart

Won't Return This Season
Carter Yakemchuk

Injured in Tuesday's Loss
Aaron Ekblad

Hand Injury "Doesn't Look Good"
Jose Fernandez

Launches Two Home Runs in Historic MLB Debut
Chase DeLauter

Exits Tuesday's Game with Foot Injury, X-Rays Come Back Negative
Chris Kirk

Has Course History on His Side in San Antonio
Billy Horschel

a Volatile Option at the Valero Texas Open
Joe Highsmith

Still Searching for Form in San Antonio
Christiaan Bezuidenhout

Looks to Find Form at the Valero Texas Open
Seiya Suzuki

to Begin a Rehab Assignment Soon
Jordan Spieth

a Horse for Course History at TPC San Antonio
Robert MacIntyre

Has One Flaw to Overcome at Valero Texas Open to be a Must-Play
Maverick McNealy

In Exceptional Form This Season
Michael Thorbjornsen

Playing Well But Still Searching For A Win
Hideki Matsuyama

Playing Well Heading to the Valero Texas Open
Si Woo Kim

Heads to Valero Texas Open For Final Tune-Up Before Masters
Cody Ponce

Diagnosed With ACL Sprain, to Miss "Significant Time"
Collin Morikawa

Withdraws From Valero Texas Open
PGA

Stephan Jaegar Still Looking For Consistency at Valero Texas Open
Nicolai Hojgaard

is Red-Hot Coming to TPC San Antonio
Tony Finau

a Risky Proposition at Valero Texas Open
Ludvig Aberg

Looks to Shake Off Collapse at Valero Texas Open
Jacob deGrom

Cleared for Season Debut on Tuesday
Colt Emerson

Signs an Eight-Year Extension with Mariners
Patrick Rodgers

Needs to Make More Birdies in San Antonio
Sepp Straka

Seeks Opportunity in San Antonio This Weekend
Nick Taylor

Could Again Struggle at the Valero Texas Open
Jose Altuve

Tallies Four Hits, Two Homers in Big Night
Miguel Vargas

Hits Grand Slam, Drives in Six in Win Over Miami
Tanner Bibee

to Start on Tuesday Against Dodgers
Chase Elliott

Takes Advantage of Pit Strategies for Second Career Martinsville Win
Denny Hamlin

Dominates but Finishes Second at Martinsville
Joey Logano

Bounces Back with Third-Place Finish at Martinsville
Ty Gibbs

Gains his Fourth Top-Five Finish of the Season at Martinsville
William Byron

Scores Another Top-Five Finish at Martinsville
Joe Pyfer

Extends His Winning Streak
Israel Adesanya

Loses Fourth Consecutive Fight
Maycee Barber

Suffers Her First Knockout Loss
Alexa Grasso

Scores Highlight-Reel Knockout
Niko Price

Retires After UFC Seattle Loss
Michael Chiesa

Victorious In His Retirement Fight
Julian Erosa

Suffers First-Round Knockout Loss
Lerryan Douglas

Scores First-Round Knockout Win In His UFC Debut
Alex Bregman

Clobbers First Two Homers in Sunday's Loss at Wrigley
Yandy Díaz

Yandy Diaz Records Five Hits, Drives in Four in Win Over Cardinals
Kyle Larson

Is Likely to Pay Off for DFS at Martinsville
Christopher Bell

Could Have Another Top-10 Performance At Martinsville
William Byron

Is A Threat to Win Again at Martinsville
Chase Elliott

is A Solid DFS Option for Martinsville Lineups
Chase Briscoe

has Plenty of Upside for DFS Lineups at Martinsville
Carlos Estévez

Carlos Estevez Unlikely to See High-Leverage Opportunities in Near Future
Jacob deGrom

Feels "Much Better," Hopeful he Can Start This Week
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Martinsville?
Ryan Preece

Is A Solid DFS Option for Martinsville Lineups
Josh Berry

Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
Carson Hocevar

May be Too Inconsistent to Start in Martinsville DFS Lineups
Austin Cindric

Is Austin Cindric Worth Rostering for DFS At Martinsville?
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
Joey Logano

Will Be Strong at Martinsville
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF