November 22, 2025
Jacksonville Jaguars rookie running back
Bhayshul Tuten (ankle) was listed as limited in practice every day this week, but was cleared from the injury report and will play in Week 12 against the Arizona Cardinals. Tuten finally had his breakout game of the season in Week 11 against the Chargers, handling 15 carries for 74 yards and a touchdown in the win. He injured his ankle during the game, which forced him to exit early, but it doesn't seem to be an issue. The rookie fourth-rounder played a season high 42.9% of the snaps and out-carried fellow running back
Travis Etienne Jr. 15 to 12 before leaving. The dynamic rookie's role should continue to expand in the coming weeks as he has looked great in his opportunities. Etienne followed a similar pattern to Tuten this week in practice as he was limited with a shoulder injury, but heads into Sunday without an injury designation. Etienne should still serve as the RB1, but Tuten has earned more work, and it could wind up being close to a 50-50 split on Sunday in Arizona. Tuten ranks as RotoBaller's RB30 in PPR formats for Week 12.
--Kyle McCarthySource: RotoBaller
November 22, 2025
Despite being benched for the opening series after missing curfew, Dallas Cowboys wide receiver
George Pickens recorded nine catches for 144 yards and a touchdown on 11 targets in Week 11 against the Las Vegas Raiders. The 24-year-old is having a breakout season, as he's hauled in 58 receptions for 908 yards and seven scores on 83 targets across his first 10 games of 2025. Pickens and the Cowboys have a difficult matchup in Week 12 against the Philadelphia Eagles. Through 11 weeks, the Eagles are tied with the Denver Broncos and Kansas City Chiefs for the fewest passing touchdowns allowed (nine) in the NFL. Philadelphia held Pickens to just three catches for 30 yards on four targets in his first matchup against them this season in Week 1. However, Pickens has been surging of late and has earned at least nine targets in four out of his last five games played. Despite the tough matchup, he profiles as a high-end fantasy WR2 in Week 12 against the Eagles.
--Will BradySource: RotoBaller
November 22, 2025
The Jacksonville Jaguars have limited quarterback
Trevor Lawrence's pass volume over the past two weeks. Lawrence attempted 23 passes in Jacksonville's Week 10 loss to the Texans, then 22 in last week's win over the Chargers. He's thrown a touchdown and an interception in both games, while making an impact on the ground, scoring his fifth rushing touchdown of the season against the Chargers. From Weeks 1 through 9, the Jaguars leaned slightly more pass-heavy, ranking ninth in pass rate over expectation (+4%). In the past two weeks, they've dropped to 23rd with a -4.2% pass rate over expectation, per Fantasy Points Data Suite. The Jaguars have started to rely more on their dynamic running back duo of
Travis Etienne Jr. and rookie
Bhayshul Tuten, which may limit Lawrence's fantasy upside. However, he draws a matchup in Week 12 against an Arizona Cardinals defense that just allowed 41 points to
Brock Purdy and the 49ers last week. Lawrence ranks as RotoBaller's QB16 for Week 12.
--Kyle McCarthySource: RotoBaller
November 22, 2025
Across seven games in 2025, Dallas Cowboys wide receiver
CeeDee Lamb has recorded 40 catches for 557 yards and two touchdowns on 61 targets. Even with fellow Dallas wideout
George Pickens in the midst of a breakout season, Lamb has earned double-digit targets in four out of the six games where he has played all four quarters. In Week 12, Lamb gets a difficult matchup when the Cowboys host the Philadelphia Eagles. For the season, the Eagles are tied with the Denver Broncos and Kansas City Chiefs for the fewest passing touchdowns allowed (nine). Philadelphia has also played some of its best defense of late, holding the Green Bay Packers and Detroit Lions to a combined 16 points over the last two weeks. Still, in his first matchup of the season against the Eagles in Week 1, Lamb recorded seven catches for 110 yards on 13 targets and could have had an even bigger game if not for a couple of uncharacteristic drops. He remains a clear must-start fantasy wide receiver in Week 12 against his division rival.
--Will BradySource: RotoBaller
November 22, 2025
Arizona Cardinals kicker
Chad Ryland has had back-to-back games under five fantasy points for the first time this season. The 26-year-old went one for two with making an extra point attempt during Week 11's matchup against the San Francisco 49ers, making a field goal within the 30 and missing his first field goal on the year from 50-plus yards out. Ryland and the Cardinals will face the Jacksonville Jaguars in Week 12, and they have allowed the 10th most passing yards this season. The Cardinals should be able to move the ball through the air to get Ryland into field goal range quite consistently. Fantasy managers can insert Ryland into lineups as a viable streaming option in Week 12.
--Wyatt McClintockSource: NFL.com
November 22, 2025
Atlanta Falcons tight end
Kyle Pitts Sr. had a quiet Week 11 with three targets and two catches for 38 yards, but he could be in line for more work in Week 12 against the Saints. Averaging over six targets, four catches, and 43 yards per game in 2025, the 25-year-old could see a couple more looks with teammate
Drake London (knee) ruled out. In Week 8, when London was also absent due to injury, the 6-foot-6 tight end garnered a team-leading nine targets, catching all nine for 59 yards.
Kirk Cousins was under center for that game, and will be again in Week 12 with
Michael Penix Jr. (knee) out for the rest of the season. Pitts was very volatile last season with Cousins as the signal caller, recording one catch or fewer in five contests. The Saints rank near the middle in terms of fantasy points allowed to opposing tight ends, so it's not an overly tough matchup, but there is some uncertainty with how this offense will look with Cousins at quarterback, so the fifth-year pro projects as a low-end TE1 this week.
--Jarod RuppSource: ESPN
November 22, 2025
The Las Vegas Raiders defense hasn't been one to target for fantasy managers this season, but they have a great opportunity in Week 12 against the Cleveland Browns with rookie quarterback
Shedeur Sanders making his first career start. Sanders was dreadful in relief of
Dillon Gabriel (concussion) in Week 11, completing four of 16 passes for 47 yards with an interception and taking two sacks. Las Vegas is middle of the pack to below average in most defensive stats, but they notably shut down the only other rookie quarterback they faced this season,
Cameron Ward, and the Titans back in Week 6. Las Vegas held them to just 3.8 yards per play, generated six sacks, and forced three turnovers on the day in a 20-10 victory. The Raiders will be looking for a repeat performance on Sunday against Cleveland. They rank as RotoBaller's No. 7 defense for Week 12.
--Kyle McCarthySource: RotoBaller
November 22, 2025
Across 10 games this season, Dallas Cowboys running back
Javonte Williams has recorded 809 rushing yards and eight touchdowns on 161 carries. The 25-year-old has dominated backfield touches in Dallas all year long and should continue to do so even after the Cowboys signed running back
Malik Davis to the active roster on Saturday. Dallas has a difficult matchup in Week 12 against the Philadelphia Eagles, who have not allowed an opposing offense to score 10 points since Week 8. Still, Philadelphia's biggest strength is against the pass, as they rank 18th in yards per carry allowed (4.3) and 21st in rushing touchdowns allowed (11) among NFL defenses. In his first matchup of the season against the Eagles in Week 1, Williams recorded 64 scrimmage yards and two touchdowns on 17 touches. He profiles as a must-start fantasy running back in Week 12.
--Will BradySource: RotoBaller
November 22, 2025
The Arizona Cardinals D/ST is looking to bounce back after a rough outing in Week 11 against the San Francisco 49ers. They gave up a season-high 41 points and were unable to force a turnover for the third time this season. In Week 12, the Cardinals D/ST will host the Jacksonville Jaguars, led by turnover-prone quarterback
Trevor Lawrence, without his top receiver,
Brian Thomas Jr. (ankle), who was ruled out with an ankle injury. Lawrence has thrown an interception in each of his last three games and has thrown eight total this season. The Cardinals' D/ST has been able to snag six interceptions this season, and will have top defensive lineman Calais Campbell active to put pressure on the Jaguars' offensive line. With a depleted Jaguars passing attack, the Arizona Cardinals D/ST is worth taking a flyer on this week.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Dallas Cowboys quarterback
Dak Prescott lit up the Las Vegas Raiders in Week 11, completing 25 of 33 pass attempts for 268 yards, four touchdowns, and zero interceptions. The 32-year-old will now face a significantly tougher test in Week 12 against the division rival Philadelphia Eagles, who have held the Green Bay Packers and Detroit Lions to single-digit points in each of the last two weeks. For the season, the Eagles are tied with the Denver Broncos and Kansas City Chiefs for the fewest passing touchdowns allowed (nine). In Prescott's first matchup against Philadelphia this season in Week 1, he completed 21 of 34 pass attempts for 188 yards and failed to throw for a touchdown. Still, Prescott is in the midst of one of his better seasons, completing 69.9% of his pass attempts for 2,587 yards, 21 touchdowns, and six interceptions across 10 games. He profiles as a low-end fantasy QB1 in Week 12 against Philadelphia.
--Will BradySource: RotoBaller
November 22, 2025
Las Vegas Raiders tight end
Michael Mayer has maintained a consistent snap share this season and has flashed the ability that made him the 35th overall pick in the 2023 NFL Draft. Mayer is firmly behind second-year tight end
Brock Bowers in the pecking order, but he is on the field a decent amount in two-tight-end sets. For the season, Mayer has recorded 21 catches for 168 yards and a touchdown on 31 targets in eight games. The 24-year-old had his best game of the season in Week 6 against the Titans without Bowers, catching five of seven targets for 70 yards. He's stayed involved with Bowers back in the fold, catching nine of 15 targets for 61 yards in the past three games. But the upside is significantly capped in a poor Raiders offense and isn't a fantasy option in most leagues.
--Kyle McCarthySource: RotoBaller
November 22, 2025
Tennessee Titans rookie running back
Kalel Mullings (ankle) is expected to be activated off of Injured Reserve for the team's Week 12 matchup against the Seattle Seahawks, according to Ian Rapoport of NFL Network. A sixth-round draft pick out of Michigan, Mullings has been sidelined by an ankle injury since Week 3. He'll join a crowded backfield mix in Tennessee that also includes
Tony Pollard and
Tyjae Spears. Pollard and Spears have basically been splitting snaps 50/50 in recent weeks, making the Titans' running back depth chart a difficult one for fantasy managers to sort out. Mullings is unlikely to play a fantasy-relevant role himself, but he could steal a few touches away from both Pollard and Spears, diminishing what has already been underwhelming fantasy production from the two veterans.
--Will BradySource: NFL Network - Ian Rapoport
November 22, 2025
Las Vegas Raiders wide receiver
Tyler Lockett has carved out a meaningful role in the offense after signing with the team on October 27. Lockett began the season with the Tennessee Titans and didn't make an impact with just 10 catches (21 targets) for 70 yards in seven games. The 33-year-old has shown he still has something left in the tank in Las Vegas, totaling more receiving yards (77) in three games with the team. The fantasy upside is still very limited as the third option behind
Brock Bowers and
Tre Tucker for a Raiders passing attack led by
Geno Smith, who has struggled mightily this season. Lockett has some appeal in Week 12 against the Browns in deeper formats, but is best left on the waiver wire in 12-team leagues.
--Kyle McCarthySource: RotoBaller
November 22, 2025
The Athletic's Dianna Russini writes that viewers should expect to see a "heavy dose" of Tampa Bay Buccaneers running back
Sean Tucker in his team's Week 12 matchup against the Los Angeles Rams on Sunday Night Football. The 24-year-old had a breakout game in Week 11, recording 140 scrimmage yards and three touchdowns against the Buffalo Bills. With Buccaneers running back
Bucky Irving (shoulder, toe) out for at least one more week, Tucker and
Rachaad White will handle the backfield work for Tampa Bay in Week 12. Based on Tucker's recent performance and Russini's reporting, it appears that White may be fading into more of a complementary role. Tucker profiles as a high-end RB3/flex option for fantasy managers in a tough matchup against the Rams.
--Will BradySource: The Athletic - Dianna Russini
November 22, 2025
Tennessee Titans rookie wide receiver
Xavier Restrepo will be active for Sunday's matchup against the Seattle Seahawks, according to Paul Kuharsky of PaulKuharsky.com. Restrepo will make his NFL debut after being on the practice squad for the first 11 weeks of the season. He will get his first opportunity as a result of
Calvin Ridley (leg) being out for the season and rookie
Elic Ayomanor (hamstring) being ruled out for Week 12. The undrafted free agent out of the University of Miami will look to make an impact as he takes the field with his college quarterback,
Cameron Ward. Restrepo had a monster final season at Miami with Ward, leading the ACC with 1,127 yards and 11 touchdowns and being named a first-team All-American. It remains to be seen how much playing time the rookie will see on Sunday, but he is an intriguing stash candidate in deeper formats and dynasty leagues.
--Kyle McCarthySource: Paul Kuharsky
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