Lost password?

Don't have an account?
Join the Best Live Fantasy Chat Community!


Receive free daily analysis


Already have an account? Log In


Forgot Password


Articles & Tools
Import Your Leagues
Weekly Rankings
Compare Any Players
Starts and Sit
Daily Fantasy
Who To Pickup
Fantasy Updates
24x7 News and Alerts

Cardinals vs 49ers Start 'Em, Sit 'Em: Rondale Moore, James Conner, Trey McBride, Elijah Mitchell, Deebo Samuel, Brandon Aiyuk

George Kittle - Fantasy Football Rankings, NFL Injury News, Draft Targets

Welcome back RotoBallers to the final game of Week 11. We're back at it as always with our Monday Night Football matchups analysis article for the 49ers vs. Cardinals. It's been yet another wild and awesome week of NFL and fantasy football action filled with big performances, new players emerging, and injuries. Hopefully, you're on the verge of winning your matchups (or already have).

Now we get one more game on Monday night to finish it off. Below you will find our matchups analysis for the Monday Night Football game between the Arizona Cardinals vs San Francisco 49ers. Hopefully, it will be an exciting game that adds to a week filled with plenty of booms, busts, and injuries.

Read our fantasy football breakdowns for these games -- the recommended starts, sits, and matchups we love heading into the Week 11 matchups. Good luck RotoBallers!

Featured Promo: The FFPC Playoff Challenge #2 is back for the Divisional Round with a massive $100,000 grand prize and $260k total prize pool. Here's the deal: no salary cap, no draft, no pickups, no subs. Choose 8 players, and as NFL teams get knocked out so will your players, so choose your team wisely. The 1,500 entries will sell out quickly, and registrations will close on Saturday January 21st at 4:30 pm ET . Don't wait - get your team now and end your fantasy football season with a shot at $100,000! Sign Up Now!


San Francisco 49ers at Arizona Cardinals

Start Time: 8:15 PM ET
Spread: 49ers -10.0
Implied Total: 49ers (25.75) vs. Cardinals (17.75)
Pace: 49ers (28th) vs. Cardinals (4th)
49ers Off. DVOA: 23.3% Pass (7th), -8.9% Rush (23rd)
Cardinals Off. DVOA: -8.8% Pass (29th), -13.8% Rush (27th)
49ers Def. DVOA:
-2.9% Pass (10th), -18.4% Rush (3rd)
Cardinals Def. DVOA: 8.2% Pass (19th), -4.5% Rush (16th)


Matchups We Love:

Christian McCaffrey (RB, SF)

McCaffrey found himself in a 50/50 split with Elijah Mitchell, limiting his upside in this game, but he still found the end zone and received the six targets. Head coach Kyle Shanahan spoke about deploying both backs, but the high-value touches are still going to McCaffrey, plus the matchup last week heavily favored running the ball. He's still an elite option with top-five upside.

George Kittle (TE, SF)

The 49ers ran the ball 41 times, electing to attempt only 28 passes, which makes it difficult for everyone in the passing attack to succeed. Kittle possesses such explosiveness and yards-after-the-catch ability, that he needs to be started to get those big games. Additionally, he gets the No. 1 matchup for tight ends, making him a must-start.


Matchups We Hate:

James Conner (RB, ARI)

It was a massive day for Conner, who received 21 carries and three targets. The Cardinals established a lead in the second quarter and never looked back, enabling Conner to score twice on the ground. The matchup against the 49ers has been the worst for fantasy running backs, so he'll need to find the end zone and catch passes to succeed in this one, which is well within his potential outcomes. There's also the possibility of a high-scoring game given the over/under.

Cardinals Quarterback

Kyler Murray missed last week's game, thrusting Colt McCoy into the starting role. McCoy filled in admirably, supporting the value of all the primary weapons and getting the victory. It's a difficult defense to move the ball on, and both of them are currently dealing with injuries, lowering their appeal. Murray would still be in the top 12 because of his rushing ability, while McCoy is best left on the bench if he starts.

UPDATE: Murray has been ruled out and is now expected to miss at least Monday's game, possibly more. McCoy has been removed from the injury report, meaning he'll be the starter once again. After what we saw last week, it's not a significant downgrade for the weapons surrounding him.


Other Matchups:

49ers Wide Receivers

As discussed above, the volume issue is impacting all their pass-catchers, which includes Deebo Samuel and Brandon Aiyuk. Samuel actually participated more as a runner than a receiver with four carries compared to two receptions, which is not ideal for his fantasy value.

Aiyuk yet again finished with more points, catching six passes for 84 yards. They're both going to be volatile top-24 receivers because of the volume, but Aiyuk has been more valuable for several weeks now.

Jimmy Garoppolo (QB, SF)

Garoppolo benefits from having so many awesome weapons but doesn't need to air out and score touchdowns to win. In this matchup though, he'll likely need to throw more often and should find the end zone at least once, making him a solid streamer, especially for managers who were waiting on Murray and needed a pivot.

DeAndre Hopkins (WR, ARI)

One of the weapons McCoy was able to support was Hopkins, who caught nine-plus passes for 90-plus yards, returning to his high-volume alpha role. The Cardinals are a better team when they feed him targets and utilize his contested catch ability. It's a tougher matchup but as the No. 1 option in the offense, he's a top-20 receiver with top-10 upside.

UPDATE: Hopkins is active and will play.

Rondale Moore (WR, ARI)

Moore also caught nine-plus passes for 90-plus yards. Since the return of Hopkins, which coincided with the Marquise Brown injury, Moore has finished in the top 24 in three straight weeks including a WR7 finish in Week 8, making him a solid top-24 receiver because of his target share.

Trey McBride (TE, ARI)

With the season-ending injury to Zach Ertz, rookie Trey McBride is expected to take over as the starting tight end for the Cardinals. In season-long lineups, it's likely a wait-and-see situation unless you're desperate with no other options. In DFS, he makes for a more intriguing boom-or-bust option.


Marquise Brown (foot)
Kyler Murray (hamstring)
Zach Ertz (knee)

Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

Win Big With RotoBaller

Be sure to also check out all of our other daily fantasy football articles and analysis to help you set those winning lineups, including this new RotoBaller YouTube video:

More Fantasy Football Analysis


Articles & Tools
Import Your Leagues
Weekly Rankings
Compare Any Players
Starts and Sit
Daily Fantasy
Who To Pickup
Fantasy Updates
24x7 News and Alerts


Drew Eubanks8 mins ago

Available On Wednesday
D'Angelo Russell10 mins ago

Heading Back To Los Angeles
Russell Westbrook28 mins ago

Traded To Utah
Will Benson33 mins ago

Reds Acquire Will Benson From The Guardians
Joel Embiid2 hours ago

Good To Go Against Celtics
Tommy Eveld2 hours ago

Signs With Reds
Killian Hayes2 hours ago

Moves Back Into Starting Lineup
A.J. Puk2 hours ago

To Compete For Rotation Spot
Michael Brantley3 hours ago

Hopes To Be Ready For Opening Day
Jamal Murray3 hours ago

Questionable For Thursday's Contest
Framber Valdez3 hours ago

Won't Pitch In World Baseball Classic
Al Horford3 hours ago

And Robert Williams III Both Out Wednesday
Monte Morris3 hours ago

Will Miss Game Against Hornets
Jared Walsh3 hours ago

Feeling Great
Bradley Beal3 hours ago

Set To Play Against Charlotte
Sam Howell3 hours ago

Likely QB1 For Commanders Heading Into Next Season
Keldon Johnson3 hours ago

Available Versus Raptors
Nick Senzel3 hours ago

Uncertain For Start Of The Season
Chris Duarte3 hours ago

Will Play Versus Miami
Kyle Kuzma3 hours ago

To Remain Out Wednesday
Shohei Ohtani3 hours ago

Angels Owner Wants To Keep Shohei Ohtani
Brock Purdy3 hours ago

To Have Surgery This Month
Donovan Mitchell3 hours ago

Darius Garland And Donovan Mitchell Out Wednesday
Aaron Ashby3 hours ago

To Be Delayed Due To Shoulder Fatigue
Jack Hughes3 hours ago

Leaves Practice Early With Injury
Aleksander Barkov4 hours ago

A Game-Time Call Thursday
Filip Chytil4 hours ago

On Four-Game Goal Streak
Joel Kiviranta4 hours ago

Out With A Lower-Body Injury
Ryan Hartman4 hours ago

Back On Top Line Wednesday
Jonas Brodin4 hours ago

Out On Wednesday
Jake Oettinger6 hours ago

Starting Wednesday Against Minnesota
Filip Gustavsson6 hours ago

Named The Starter Versus Dallas
Robert Williams6 hours ago

III Downgraded To Questionable
Spencer Martin6 hours ago

Minds The Crease Wednesday
Al Horford6 hours ago

Questionable On Wednesday
Jaylen Brown6 hours ago

Good To Go Wednesday
Jeremy Sochan6 hours ago

Misses Another Game Wednesday
Tre Jones6 hours ago

Remains Out Wednesday
Donovan Mitchell7 hours ago

Questionable Wednesday
Darius Garland7 hours ago

Questionable For Wednesday
James Naile7 hours ago

Cardinals Designate James Naile For Assignment
Anthony Misiewicz7 hours ago

Cardinals Acquire Anthony Misiewicz
Kyrie Irving8 hours ago

To Debut For Mavericks On Wednesday
Los Angles Rams9 hours ago

Aaron Donald Coming Back For Another Season
Josh Jacobs9 hours ago

Raiders Expected To Use Franchise Tag On Josh Jacobs
Shane Lowry9 hours ago

Set To Make First U.S. Start Of 2023 This Week
Tony Pollard9 hours ago

Expected To Receive Franchise Tag
PGA9 hours ago

Alex Noren A Dark-Horse Contender This Week
PGA10 hours ago

J.T. Poston Heads To Phoenix In Hot Form
Cameron Young10 hours ago

Continues To Impress
Patrick Cantlay10 hours ago

An Elite Fantasy Option At WM Phoenix Open
Corey Conners10 hours ago

Remains A Ball-Striking Machine
PGA10 hours ago

Matt Fitzpatrick Hopes To Rebound In Phoenix
Rory McIlroy10 hours ago

Looks To Stay Hot In Phoenix
Justin Thomas11 hours ago

Has Thrived At WM Phoenix Open
Evgeni Malkin13 hours ago

Bags Two Assists
John Klingberg13 hours ago

Tallies Two Assists Tuesday
Nikita Kucherov13 hours ago

Extends Home Point Streak
Andre Burakovsky13 hours ago

Goes Down On First Shift
Nick Paul13 hours ago

Hurt In Tuesday's Game
Troy Terry13 hours ago

Out Day-To-Day
Brayden Point19 hours ago

Scores Twice Against Sharks
Erik Karlsson19 hours ago

Records Three Points In Overtime Victory
Jack Campbell19 hours ago

Collects Victory Against Red Wings
Connor McDavid19 hours ago

Picks Up Assist In Victory
Bo Horvat20 hours ago

Scores First Goal In Islanders Jersey
Adin Hill20 hours ago

Earns Win Against Predators
Tejay Antone21 hours ago

Dealing With Flexor Strain
Bo Bichette21 hours ago

Blue Jays, Bo Bichette Avoid Arbitration
Rickie Fowler23 hours ago

Has Good History At WM Phoenix Open
Sam Burns23 hours ago

Looks To Keep Improving At Phoenix
Scottie Scheffler24 hours ago

Could Stay Near The Top At Phoenix
Hayden Buckley24 hours ago

Poised For Rebound At WM Phoenix Open
Matthew NeSmith24 hours ago

Still Trying To Find Fall Form
PGA1 day ago

Sungjae Im Poised To Keep Rolling In Phoenix
1 day ago

Tom Kim Expects To Contend At Phoenix This Week
Derek Carr1 day ago

Saints Granted Permission To Visit With Derek Carr
Kyle Tucker1 day ago

Astros, Kyle Tucker Have Discussed Extension
Jon Berti1 day ago

Marlins, Jon Berti Avoid Arbitration
DJ LeMahieu1 day ago

Looks Back To Old Self
Josh Donaldson1 day ago

Projected To Start At 3B For Yankees
Oswald Peraza1 day ago

Yankees Impressed With Oswald Peraza
Anthony Volpe1 day ago

On A Mission
Matt Gage1 day ago

Blue Jays Place Matt Gage On Unconditional Release Waivers
Phillip Diehl1 day ago

Guardians Agree To Minor-League Deal With Phillip Diehl
Derrick Lewis1 day ago

Rough Times Continue For Derrick Lewis
Serghei Spivac1 day ago

Sergey Spivak Earns Huge Victory On Saturday
MMA1 day ago

Jung Da Un Unable To Do Enough To Earn Decision
Devin Clark1 day ago

Eeks Out Close Decision Win
Blagoy Ivanov1 day ago

Unable To Stop Recent Slide
Marcin Tybura1 day ago

Continues To Shine With Latest Victory
Kyle Nelson1 day ago

Saved From Defeat With Late Point Deduction
MMA1 day ago

Choi Doo-ho's Point Deduction Takes Away A Victory
Yusaku Kinoshita1 day ago

Unable To Score A Victory In Debut
Adam Fugitt1 day ago

Dominates With First-Round Finish
A.J. Green2 days ago

Announces His Retirement
Brock Purdy2 days ago

Leaning Toward Surgery?
Mecole Hardman2 days ago

Lands On Injured Reserve
Clyde Edwards-Helaire2 days ago

Chiefs Activate Clyde Edwards-Helaire From IR
Zach Wilson3 days ago

Jets Have No Plans To Trade Zach Wilson
Cleveland Browns3 days ago

Myles Garrett Dislocates Toe At Pro Bowl Games
Joey Logano3 days ago

Facing Different Reality At Los Angeles
Ross Chastain3 days ago

And The Clash On Sunday
Ty Gibbs3 days ago

Has To Race Into Coliseum Main Event
Kyle Larson3 days ago

Bit Of A Wildcard At Los Angeles
Alex Bowman3 days ago

Qualified Ninth At Los Angeles
NASCAR3 days ago

A.J. Allmendinger Has Exciting Saturday At Coliseum
Denny Hamlin3 days ago

Starts Second In Heat Three At Coliseum
Austin Dillon3 days ago

Continues Chevy Theme In Los Angeles
Aric Almirola3 days ago

Rises To Fifth In Qualifying Saturday
William Byron3 days ago

Qualifies Fourth For Sunday At Los Angeles
Christopher Bell4 days ago

Surprises Some At Coliseum Saturday
Kyle Busch4 days ago

Loves Los Angeles Again On Saturday
Justin Haley4 days ago

Heats Up Coliseum Track Saturday
Josh Jacobs4 days ago

Won't Settle In Extension Talks
Mecole Hardman5 days ago

Doubtful For Super Bowl
JuJu Smith-Schuster5 days ago

Kadarius Toney Questionable
Derek Carr5 days ago

Won't Extend Contract Trigger Date
Derek Carr6 days ago

Expected To Draw Plenty Of Interest
Aaron Rodgers6 days ago

: "I'm Not Going To San Fran"