👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

FanDuel, DraftKings MNF DFS Lineup Picks: Daily Fantasy Football for Week 10

Gage Bridgford (@GbridgfordNFL) highlights the top FanDuel NFL DFS lineup picks for Monday Night Football for Week 10 of the 2019 season, and a couple of sleepers to consider while building MNF daily fantasy rosters.

Monday Night Football is here, and the undefeated San Francisco 49ers (8-0) are set to host the division-rival Seattle Seahawks (7-2). This will be the best opponent the 49ers have faced all season, and, if they're able to come out with a win, analysts and fans alike will certainly take a much different stance on this team.

However, we're not here for that. We're here to make some money in daily fantasy lineups. The Seahawks have some electric wide receivers, especially with wideout Josh Gordon now in the mix. On the 49ers' side, their running backs have been churning out production like crazy all season.

Whether you're playing on FanDuel or DraftKings, the slightest lineup constructions can make all the difference. Choosing one player over another is the difference between winning a little or a lot. So, let's look at how we're going to construct our lineups.

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

DFS Quarterbacks - Week 10 Picks

Russell Wilson, Seattle Seahawks - FanDuel $16,000 / DraftKings $11,400

Arguably the frontrunner for the MVP so far, Seattle Seahawks quarterback Russell Wilson has been lighting it up all year. He's over 2,500 yards on the year with 22 touchdowns and just one interception. The San Francisco 49ers Defense has been the best in football, and, against the pass this season, they've been allowing just 138.1 yards per game. In this game, you only have two quarterback options. Wilson is incredible, and he'd be tough to keep out of your lineups, although there is a case.

Jimmy Garoppolo, San Francisco 49ers - FanDuel $15,000 / DraftKings $11,000

Your other option for the week is San Francisco 49ers quarterback Jimmy Garoppolo. As good as the 49ers have been on defense, the Seahawks Defense has been abysmal. They're allowing the fifth-most yards through the air, and Garoppolo is coming off of his best game of the season, in which he threw for over 300 yards and four touchdowns. Garoppolo is a little cheaper than Wilson, and, if you think the 49ers defense will be able to slow down Wilson, get Jimmy G in the fold.

 

DFS Running Backs - Week 10 Picks

Chris Carson, SEA - FanDuel $12,000 / DraftKings $8,600

Seattle Seahawks running back Chris Carson has been one of the more consistent running backs all season. While the team has gone to more of an air-it-out style, they still make an effort to keep him involved. He's received at least 15 carries in every game this season. He's the most expensive of the guys we're going to look at, so it would make plenty of sense to look elsewhere, despite the consistent volume that he'll get on the night.

Tevin Coleman, SF - FanDuel $11,000 / DraftKings $8,200

After getting into the end zone four times against the Carolina Panthers, 49ers running back Tevin Coleman wasn't able to punch one in last week. The 49ers average over 170 rushing yards per game, and they could be forced to throw this week against a Seahawks defense that is 13th in the NFL in yards allowed on the ground per game. Coleman also doesn't add much in the passing game, as he has just 10 catches on the season for just 74 yards.

Matt Breida, SF - FanDuel $9,000 / DraftKings $6,200

49ers running back Matt Breida has struggled with injuries this season, but he always finds a way to be involved thanks to his abilities as a receiver and hard-nosed running style. He comes in at a severely lowered price tag on Monday which gives you more lineup flexibility if you choose to spend up at another position, such as a wide receiver. He only has two total touchdowns on the year, which both came against the Cleveland Browns, but the upside is there for him this week.

 

DFS Wide Receivers - Week 10 Picks

Tyler Lockett, SEA - FanDuel $13,500 / DraftKings $10,400

Seahawks wideout Tyler Lockett exploded last week when he saw 18 targets, and fantasy owners everywhere were pleased. This week, he'll be working against the league's best passing defense, and, if you choose to play Wilson, Lockett is your stack receiver. He's working out of the slot where he has a slight advantage over the outside cornerbacks. Wilson looks his way most frequently, and he gives you a sense of confidence that he'll have some production.

Emmanuel Sanders, SF - FanDuel $11,500 / DraftKings $10,200

The only 49ers receiver that I have any confidence in playing is Emmanuel Sanders. He's gotten into the end zone in each of his first two games with the 49ers, and he saw nine targets go his way last week. He's the best and most consistent wide receiver that Garoppolo has to throw to. Against this Seahawks defense, Sanders should have no problem continuing his production.

D.K. Metcalf, SEA - FanDuel $12,500 / DraftKings $7,800

Seahawks wideout DK Metcalf is a little pricy for me on FanDuel, but I like him over on DraftKings where he's a bit cheaper. Metcalf's size and speed typically win him a lot of routes with ease. This week, the 49ers' cornerbacks have the size to match up with him at the line of scrimmage. If he gets bumped off of his routes, he'll have next to no production. However, he only needs one or two clean breaks to have a huge night through the air.

 

DFS Tight Ends - Week 10 Picks

Jacob Hollister, SEA - FanDuel $8,500 / DraftKings $4,600

If you're starting a tight end in this game, it's Jacob Hollister of the Seahawks. He's shown a small connection with Wilson over the past few weeks, but you still don't have an overwhelming amount of confidence in him. Hollister is more of a dart throw type of player that you play to be contrarian and hope he hits. Don't rely on him too heavily.

*Note: San Francisco 49ers tight end George Kittle (knee) is doubtful to play, and he was therefore not considered for this article.*

 

DFS Defenses - Week 10 Picks

San Francisco 49ers Defense - DraftKings $5,200

This has been one of the best defenses in the NFL, and they have made their hay rushing the quarterback. Wilson has been sacked 22 times this season, and he has just one game where he wasn't taken down. The issue you run into with Wilson is that he takes care of the ball well with just one interception and no fumbles on the year. Unless you're forced to, I would avoid the 49ers defense this week. Division rivals always play each other tight, as evidenced by the Arizona Cardinals losing to the 49ers by just three last week. Find someone else to spend your money on this week.

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
Daniel Suarez

has Little Upside for Darlington DFS Lineups
Bryce Young

a Potential Trade Target in Dynasty Leagues?
Devaughn Vele

Worth Buying Low on in Dynasty Leagues?
Darnell Washington

Climbs Up the Depth Chart
Adonai Mitchell

Trending Up After Quarterback Change?
Saquon Barkley

to Benefit From New-Look Offense in 2026?
Michael Wilson

On Track to be Cardinals' Top Fantasy Receiver?
Victor Wembanyama

Good to Go Versus Pacers
Seiya Suzuki

Won't be Ready for Opening Day
Kawhi Leonard

Ready to Face Dallas Saturday
Draymond Green

Available Saturday Against Atlanta
De'Anthony Melton

Cleared to Play Saturday
Jalen Johnson

Sidelined Saturday
Alperen Sengün

Alperen Sengun Will Play Against Heat
Kristaps Porzingis

Out Saturday Against Hawks
Jaylon Tyson

Ruled Out Versus Pelicans
Donovan Mitchell

Available Saturday Against New Orleans
Dylan Larkin

Remains Out Saturday
Austin Reaves

Cleared to Play Saturday
Jake Sanderson

Could Return in 7-10 Days
Morgan Rielly

Unavailable Saturday
Urho Vaakanainen

Considered Week-to-Week
Noah Laba

Out Week-to-Week
Tyler Toffoli

Questionable for Road Trip
Victor Hedman

Won't Play Against Oilers
Gleyber Torres

Clear to Return on Monday
Konnor Griffin

Assigned to Minor-League Camp
Jake Ferguson

Tails Off Late in 2025
Shedeur Sanders

Set to Face Competition Ahead of 2026
Tyreek Hill

Remains a Free Agent
Brock Bowers

Set for a Major Quarterback Upgrade?
Mack Hollins

Still Trending Up in New England?
Malik Washington

a Breakout Candidate Going into Year 3?
Mike Gesicki

a Bounce-Back Candidate in Third Year in Cincy
Xavier Legette

the Panthers' WR3 Heading into 2026?
Rashod Bateman

Dynasty Stock is on Life Support
Gleyber Torres

Scratched From Lineup on Saturday With Lower-Back Tightness
DJ Giddens

an Intriguing Handcuff Despite Minimal Standalone Value
Hunter Henry

Set to Collect Some Vacated Targets?
AJ Barner

Firmly Positioned Atop Depth Chart
Cedric Tillman

Dynasty Managers Losing Patience?
Josh Jacobs

Remains a Strong RB1 Option
Devon Witherspoon

Seahawks Pick Up Devon Witherspoon's Fifth-Year Option
Aaron Nesmith

Could Miss Saturday's Game
Andrew Nembhard

Could Miss Fourth Straight Game
Brice Sensabaugh

Remains Out Saturday
Grayson Allen

Could Miss Third Straight Game
Royce O'Neale

Unlikely to Play Saturday
Kristaps Porzingis

Exits Early, Likely Out Saturday
Landry Shamet

Leaves Friday's Game with Knee Issue
Jake Allen

has Excellent Performance in Defeat
Logan Thompson

Nearly Perfect In Victory
Pascal Siakam

Uncertain for Saturday Against Spurs
Stephon Castle

Questionable for Saturday Versus Pacers
Donovan Mitchell

Questionable as Cavaliers Visit New Orleans
Kevin Porter Jr.

Listed as Questionable Against Phoenix
Tanner Bibee

to Take the Ball on Opening Day
Logan Webb

to Start on Opening Day for Giants
Cristopher Sánchez

Cristopher Sanchez to Start on Opening Day for Phillies
Chris Sale

Braves Name Chris Sale as Their Opening Day Starter
Kyle Stowers

Leaves Friday's Game With Hamstring Tightness
Jasson Domínguez

Jasson Dominguez Optioned to Triple-A
Tyler Toffoli

Won't Play Saturday
Joel Armia

Ready to Return From Back Injury
Joel Eriksson Ek

Kirill Kaprizov, Joel Eriksson Ek to Remain Out Saturday
Ross Colton

Still Out Friday
Yan Kuznetsov

Remains Sidelined Friday
Shayne Gostisbehere

Misses Seventh Straight Contest
Jacob Misiorowski

Named Opening Day Starter
Morgan Rielly

Cleared to Play Friday
Mike Trout

X-Rays Come Back Negative on Mike Trout's Hand
Dylan Crews

Optioned to Triple-A Rochester
Lerone Murphy

Set For UFC London Main Event
Movsar Evloev

Looks To Remain Unbeaten
Michael Aswell

Jr. An Underdog At UFC London
Luke Riley

Set For UFC London Co-Main Event
Joe Ryan

Named Opening Day Starter for Twins
Sam Patterson

Looks To Extend His Win Streak
Michael Page

Set For Welterweight Bout
Austen Lane

In Dire Need Of Victory
Iwo Baraniewski

A Favorite At UFC London
Sergei Bobrovsky

Shuts Out Oilers with 21 Saves
Trent Frederic

Exits Early Against Panthers
Mason Appleton

Hurt Thursday Night
Tyler Toffoli

Suffers Lower-Body Injury in Thursday's Loss
Victor Hedman

Makes Early Exit Due to Illness
Francisco Alvarez

Pulled Early Thursday With Back Tightness
Luis Severino

to Start for A's on Opening Day
Logan Gilbert

Named Mariners Opening Day Starter
José Ramírez

Jose Ramirez Back in Cactus League Lineup on Thursday
Hayden Birdsong

to Have Tommy John Surgery, Miss Entire 2026 Season
Zack Wheeler

to Pitch in Minor-League Game on Monday
Paul Skenes

Pirates Officially Name Paul Skenes Their Opening Day Starter
Akshay Bhatia

Withdraws From Valspar Championship
CFB

Alberto Mendoza Drawing Positive Reviews at Georgia Tech
CFB

Anthony Colandrea Impressing in Nebraska's Spring Practices
J.J. Spaun

Offers Upside Despite Poor Course History at Innisbrook
Aaron Rai

Looks to Bounce Back at Valspar Championship
Johnny Keefer

Brings Ball-Striking Upside to Valspar Championship
Billy Horschel

a Volatile Play at Valspar Championship
Ben Griffin

Looks to Rebound at the Valspar Championship
Corey Conners

Brings Elite Ball-Striking to Valspar Championship
Xander Schauffele

Trending In The Right Direction For Valspar Championship
Sahith Theegala

Has Shot to Challenge at Valspar Championship
Mackenzie Hughes

Looking to Bounce Back at Valspar Championship
Nicolai Hojgaard

Finding Rhythm For Valspar Championship
Matt Fitzpatrick

Continues Hot Start to 2026 Heading to Valspar Championship
Pierceson Coody

Heads to Valspar Championship Following Two Missed Cuts
Wyndham Clark

Searching for Momentum at Valspar Championship
Justin Thomas

Is Justin Thomas Back Ahead of This Week's Valspar Championship?
Jordan Spieth

to Bounce Back at Favored Valspar Championship?
Brooks Koepka

is Starting to Find His Groove Again Ahead of Valspar Championship
Viktor Hovland

is One of The Best DFS Plays at Innesbrook
Rasmus Hojgaard

to Get Back on Track at Valspar Championship
Tony Finau

is Again a Scary Option at Valspar Championship
Blades Brown

Continues PGA Tour Run at Valspar Championship
Josh Emmett

Suffers First-Round TKO Loss
Kevin Vallejos

Scores First-Round TKO
Amanda Lemos

Drops Back-To-Back Fights
Gillian Robertson

Extends Her Win Streak
Andre Fili

Drops Decision on Saturday
Denny Hamlin

Dominates and Gets His Third Career Las Vegas Win
Chase Elliott

Earns Runner-Up Finish at Las Vegas
William Byron

Wins A Stage and Finishes Third at Las Vegas
Christopher Bell

Finishes Fourth at Las Vegas After Strong Run
Kyle Larson

Fades to Seventh Despite Leading Laps Early at Las Vegas
Andre Fili

Jose Delgado Edges Andre Fili in Split-Decision Win
Oumar Sy

Suffers First-Round Submission Loss
Ion Cutelaba

Returns To The Win Column
CFB

CJ Carr Enters Sophomore Season as Heisman Favorite
CFB

Aaron Philo Not a Lock to be Florida's Starting QB?
CFB

George MacIntyre the Favorite to Win Tennessee Quarterback Battle?
CFB

Keelon Russell, Austin Mack Battling for Alabama QB1 Duties
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF