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DraftKings Daily Fantasy Baseball Picks (5/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 22nd, 2019. Austyn Varney's MLB DFS analysis and sleepers for building optimal DFS rosters.

Tonight's main slate starts at 7:05pm eastern and covers 11 games. There's also an all day slate starting at 1:05pm eastern that includes a few extra early games. We'll be focusing on the main slate, where we have plenty of pricey options to look through and some value plays to fit in as well. Let's dive in to each position!

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/22/2019. These picks will range from some of the elite players to mid-priced options and value plays.

We also provide DFS lineup picks for DraftKings and other sports. If you have any questions or comments, feel free to contact me on Twitter @varneydfs.

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DraftKings DFS Pitchers

Gerrit Cole, HOU (vs. CWS) ($12,000)

Gerrit Cole, Max Scherzer, and Jacob deGrom make up your top three pitching options. Scherzer and deGrom will be dueling and neither are a clear favorite. Cole on the other hand, is an insane -350 favorite. That’s as big as it gets in baseball. The White Sox aren’t a terrible team, but rank 17th against right-handers and strikeout at a healthy 26% clip. Gerrit Cole has been great over his last few starts and this isn’t the matchup to mess up his groove. Cole is expensive, but the top option in both formats if you can fit him.

Max Fried, ATL (@ SFG) ($8,500)

If you’re wanting to save a few dollars for your SP2, look no further than Max Fried. Fried can be a bit up and down, but he’s held both lefties and righties under a .285 wOBA. He’s striking out 8.5 batters per nine and has his command under control down to 1.5 BB/9. He enters one of the biggest ballparks in the game in AT&T Park to face off with an underwhelming Giants lineup that strikes out and struggles to hit for power. The Braves are favorites on the road and I could see a big day out of Fried for an affordable tag.

 

DraftKings DFS Infielders

C - Gary Sanchez, NYY (@BAL) ($5,500)

It doesn’t get much worse than Dan Straily. Through 8 starts this season, he’s gone 30.2 innings and has given up 29 earned runs. He now faces a tough Yankees lineup that has been hitting well without their best players. Gary Sanchez is still around, though, and he’s making his presence known. He may be expensive, but he’s so much stronger than any other catcher and has legitimate 2-HR upside every night. If you don’t want to spend much at the position, Buster Posey is always worth a look against a lefty.

1B - Yuli Gurriel, HOU (vs. CWS) ($3,900)

It’s starting to look like the career of Ivan Nova is coming to a close. Unless he dramatically changes his approach, he’s not going to last long. He’s been teed off on by both sides of the plate and hasn’t shown any signs of unluckiness or regression. He now faces off with the Astros, who’ll give him no break. If you want to save at 1B, Yuli Gurriel is consistent and will get a ton of RBI opportunities. He’s also only $3,900 on DraftKings and gives you cheap exposure to the top offense of the night. You can play him at third as well.

2B - Starlin Castro, MIA (@ DET) ($2,900)

Starlin Castro is extremely cheap on DK and I don't see the reason for it. Yes, he's not the greatest hitter, but he's in the heart of a Marlins lineup that's projected to put up 4.5 runs tonight. Castro has also always destroyed lefties. He's currently sporting a .390 wOBA and has shown no signs of slowing down. Daniel Norris has struggled against righties and the Marlins are better against southpaws. Castro and Anderson are both extremely cheap and I love pairing them with a more expensive combo from another team.

SS - Jorge Polanco, MIN (@LAA) ($4,700)

Jorge Polanco is one of my favorites hitters in baseball to roster. He seems to always com through in one way or another, and always has a big game when the Twins put up runs. He’s hitting .335 on the season with 8 home runs and a .400+ wOBA. Tonight, he faces off against Matt Harvey and the Angels. Harvey has been pitiful against lefties, allowing a .395 wOBA and 7 homers in just over 40 innings. The Twins are a juggernaut offense and Polanco himself is a tough out every time. As a switch-hitter, he always has the platoon advantage and will never see huge mismatch. He’s expensive, but cheaper than a lot of the other SS’s and he shouldn’t be. He’s my favorite of all, no matter the price.

3B - Alex Bregman, HOU (vs. CWS) ($5,500)

Bregman is expensive, but he may be worth paying up for on this slate. He’s one of the all-around best hitters in baseball and has slaughtered righties with a .427 wOBA followed by 11 homers. Ivan Nova will be lucky to last four innings tonight and it’s safe to expect five at-bats out of the Astros tonight. Now can Nova go through a CGSO? Yes, it’s baseball, but the Astros have the highest implied total on the night and are certainly safe to plant your flag on. If you want to go cheap here, just move to Gurriel.

 

DraftKings DFS Outfielders

OF - Mike Trout, LAA (vs. MIN) ($5,700)

If you’re going to pay up for an outfielder, Mike Trout is facing off against a lefty that likes to throw low in the zone. We know Trout lives in the lower third and he will make Perez pay for every mistake he makes. Perez has been pretty good this year on the surface, but a 4.23 xFIP and .263 BABIP tell a different story. He’s been a bit lucky, but by no means bad. He’s just no match for Mike Trout, who’s sported a .400+ wOBA against lefties for years now. There isn’t a ton of money to spend for fun on this slate, but Trout is the way to go if you can and I doubt he’s higher than 10% owned.

OF - Josh Reddick, HOU (vs. CWS) ($4,400)

We’ll close out our Astros love with Josh Reddick. For whatever reason, he’s cheaper than Marisnick and lets you spend up elsewhere while maintaining huge upside. It’s not like Reddick is having a bad year, either. His power numbers are a bit off, but he’s had four hit the warning track and could easily be at 8. Ivan Nova has always struggled against lefties, but a .425 wOBA is just unacceptable. He doesn’t have a strikeout pitch and can’t hold a runner. The Astros are the top offense of the night and it just comes down to fitting them in. There’s a reason for the price.

OF - Brian Anderson, MIA (@ DET) ($3,100)

This one may come out of left field, or third base, but you know what I mean. Brian Anderson has cooled off from his rookie season, but is still holding a wOBA over .340 against lefties. He has a power stroke and is the most consistent bat in the lineup with RISP. Daniel Norris is terrible against right-handers and struggles with the long ball. The Marlins aren’t a very exciting offense, but they’re better against lefties and Anderson has been swinging the bat nicely. He’s also extremely cheap and has solid positional versatility.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
Treylon Burks

A Treylon Burks Dynasty Resurgence Looking Highly Unlikely
Cedric Coward

Aims to Improve Ball-Handling Ability
Cole Kmet

a Low-Cost Dynasty Depth Piece
Jonas Valančiūnas

Jonas Valanciunas Attracting Interest From Europe
Quinn Ewers

a Dynasty Hold with Limited Upside
Giannis Antetokounmpo

Celtics Reportedly Not Interested in Giannis Antetokounmpo
Calvin Austin III

Can Calvin Austin III Build Dynasty Value in New York?
LeBron James

Reportedly Waiting for Lakers Approach
Jauan Jennings

Is Jauan Jennings' Brief Dynasty Peak Behind Him?
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Younghoe Koo

Jets Sign Kicker Younghoe Koo on Wednesday
Quinn Ewers

Looks Good in Wednesday's OTA Practice
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Ty Johnson

Taking Part in OTAs
Ja'Tavion Sanders

Cutting Laterally at OTAs
Tre' Harris

has Been a Top-Three Receiver During Offseason Program
Makai Lemon

Already Working With Starters in OTAs
AJ Barner

Undergoes Offseason Procedures, Not Taking Part in OTAs
Zach Charbonnet

Might Not Return Until Midseason
Von Miller

"For Sure" Plans to Play in 2026
Alvin Kamara

Not at OTAs But Preparing for the 2026 Season
Lamar Jackson

"Absolutely" Wants to Stay With Ravens Long-Term
Mason Plumlee

NBA Upgrades Mason Plumlee's Foul to a Flagrant 1
Victor Wembanyama

Receives Warning From NBA
Atlanta Hawks

Hawks Promote Onsi Saleh to President of Basketball Operations
Jalen Williams

Listed as Questionable for Game 6
Ajay Mitchell

Ruled Out for Game 6
Michael Penix Jr.

Not Cleared for 11-on-11 Work
Jacoby Brissett

Still Absent From OTAs This Week
George Kittle

Still Hoping to be Ready for Week 1
Micah Parsons

Expected to Open Training Camp on the PUP List
Tucker Kraft

Packers Hopeful Tucker Kraft Will Participate in Training Camp
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
De'Aaron Fox

Limited to Nine Points in Game 5 Loss
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
Julian Champagnie

Notches 22 Points With Four Triples Tuesday
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
Jared McCain

Produces 20 Points in First Playoff Start
Shai Gilgeous-Alexander

Scores Game-High 32 Points in Game 5 Win
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Zion Williamson

to See More Versatile Role
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF