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DraftKings CFB DFS Picks - Daily Fantasy College Football Advice for 10/6

Can't believe it's already week six of the college football season, but here we are. The benefit of being nearly halfway through the season is that we have a much clearer picture of which teams are good, and which of those are frauds we were fooled by in the earlier weeks of the 2018 season. The only downside to this week's 10 game slate is that there are more than a handful of potential blowout games.

Speaking of blowouts, that inclination comes directly from the Vegas lines I have been pouring over this week. The three games with the top projected points totals - which happen to be the only three with an over/under above 60 - all happen to have spreads of 20+ points. Yikes. That really limits my pool of "games I adore because of Vegas projections", but there are two that stick out as good targets. The Texas-Oklahoma game has an over/under of 60.5, with the Sooners favored by 7. And the second best game from this lens is the Iowa State at Oklahoma State matchup, with an over/under of 54.5 and the Cowboys favored by 9.5

In this article, I will be providing you with my daily fantasy college football lineup picks for DraftKings on 10/6/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @kpLuch.

 

DraftKings DFS Quarterbacks

Kyler Murray - QB, vs Texas ($10,200)

There may be a few quarterbacks this week who have safer point floors than Murray - Will Grier and Dwayne Haskins, for instance - but I don't feel that any have the ceiling that Murray has. And this isn't a point chasing play. Yes, Murray went completely off last week thanks to six touchdowns through the air and rushing for another, but this is about matchup and the projected competitiveness of this game. Many of the top (priced) quarterbacks in play this weekend have cupcake matchups, and I'm afraid those offenses will be taking their collective feet off the gas pedal early - this shouldn't be the case in this storied rivalry. The game has one of the most attractive over/unders at 60.5, and a spread of just 7. What makes this more enticing is that the Sooner have the top offense in the S&P+ rankings, and they face a Texas team that ranks 80th on defense by those same standards. Led by Murray, the Sooner should be moving the ball well and chasing points for all four quarters.

Taylor Cornelius - QB, vs Iowa State ($8,400)

Cowboy quarterback Taylor Cornelius has played with serious consistency this year, only failing to reach his price implied point total once through five weeks of play. He has a moderate price tag for the production he's had, and I think this game environment raises his points floor and ceiling this week. As noted above, this is one of the most attractive games whilst viewing the slate from a Vegas perspective, albeit on a pretty ugly slate. As for the actual matchup itself, Iowa State is no slouch defensively, but there is a big enough discrepancy between their pass defense and run defense that I think there's an edge to be had here. The Cowboys do have a stud running back in Justice Hall, but the Cyclones have the talent up front in the box to keep him in check. As their pass defense is far inferior, I think this game script sets up well for Cornelius to fire 30+ passes and find success through the air.

Also Consider: Will Grier - QB, vs Kansas ($10,400)

 

DraftKings DFS Running Backs

J.K. Dobbins - RB, vs Indiana ($7,500)

Pound for pound (okay, dollar for dollar, rather) Dobbins is my favorite play in week six of college football daily fantasy. I love his floor, and I'm pretty enticed by his ceiling as well against the Hoosiers. In what appeared as a truer time share earlier in the season between Dobbins and Weber, Dobbins seems to have separated a bit and emeraged as the clear #1 (although, as you'll see in my Also Consider - I think Weber is a fine cash play plug thanks the matchup and price) and has received the lion's share of the carries in the past two weeks. This Indiana team actually ranks pretty well defensively, but they haven't seen a beast like the Buckeyes offense yet, and they, too, have a lopsided unit. Their defensive backfield is pretty talented, while their front seven is young and lost a lot of key guys from the year before. I think Dobbins is going to have his number called early and often en route to a big game.

Kennedy McKoy - RB, vs Kansas ($5,000)

A game with an incredibly high point total and a big spread? This has the makings of a blowout game that can flip a game script to "feed the running backs all second half to control the clock". I like McKoy as both a sleeper and a value play in week six. He's failed to meet salary based expectations only once, and as such I think he's a fairly safe cash play. He's been fed the rock at least 11 times in each of the last three weeks, and due to the game script switch I can see happening, I like him as a high ROI guy you can plug into tournament lineups as well.  The fact that Kansas has allowed an average of 177 yards per game on the ground makes him even more enticing.

Also Consider: Mike Weber - RB, vs Indiana ($5,900)

 

DraftKings DFS Wide Receivers

Marquise Brown - WR, vs Texas ($7,700)

The Texas Longhorn defense is without a doubt improved - but they still have a glaring weakness, and that's allowing big plays. Enter Marquise Brown, one of Kyler Murray's favorite targets and a big-time deep threat receiver. He's found the endzone at least once every week this season (save for the Army game), and he's eclipsed 130 yards receiving in three of five games. The Vegas projections for this game certainly help to elevate his status, and he should find some soft spots in this Longhorns secondary.

Whop Philyor - WR, at Ohio State ($3,700)

Philyo's status - he banged up his angle two weeks ago - is still not completely known, so this is a spot to keep an eye on. If he's able to go, however, I think he becomes an incredible value with a fairly high ceiling relative to his price. He's a dyanmic playmaker that the Hoosiers like to get the ball to in space, and he had a monster 13-catch, 138 yard performance against Michigan State in his last piece of action. The projected game script and score also make this matchup more enticing, as the Hoosiers will likely be forced to throw the ball often to keep pace with the Buckeyes. If Philyor is unable to go, Nick Westbrook is a fine cash option and Donovan Hale (both Hooosier receivers) have their respective floors raised a bit - but reserve Hale for tournament play only.

Also Consider: Jerry Jeudy - WR, at Arkansas ($6,900)

More NCAA Football Analysis

REAL-TIME FANTASY NEWS

Micah Parsons

Eyeing a Mid-October Return After Having Another Knee Surgery
Rome Odunze

Foot Injury Still an Issue Going into 2026 Season?
Ketel Marte

Out on Wednesday With Back, Hamstring Injuries
Mitchell Robinson

is Available for Game 1 on Wednesday
Kawhi Leonard

Unlikely to be Traded
Chicago Bulls

Bulls Host Potential Lottery Picks for Workout
Washington Wizards

Wizards Considering Trading Down in Draft
Russell Wilson

Retiring From the NFL
Corbin Burnes

has Teres Major Strain, Unlikely to Return Until September
Malik Davis

Appears to be the Front-Runner for RB2 Job in Dallas
Kayshon Boutte

to Compete for Snaps in Three-Receiver Sets
Alvin Kamara

Attends OTAs on Wednesday
Andrei Iosivas

Is it Time for Dynasty Managers to Drop Andrei Iosivas?
Tyjae Spears

Is Tyjae Spears Droppable in Dynasty Formats?
Jaylen Wright

the Dynasty Handcuff Running Back to Own in Miami?
Colby Parkinson

Facing Likely Regression After Career Year in 2025
Omarion Hampton

Remains a High-End Dynasty RB1 Despite Injury History
Rickie Fowler

Looks To Continue Resurgent Season At Memorial
Ollie Gordon II

Is Ollie Gordon II Still Worthy of a Dynasty Roster Spot?
Justin Herbert

Overhauling his Footwork This Offseason
De'Von Achane

Doing Individual Drills at Minicamp
Ashton Jeanty

Raiders Emphasizing Ashton Jeanty's Progress as Their Lead Back
Marvin Harrison Jr.

Still on the Mend From 2025 Injuries
Brandon Aiyuk

Warrant Issued for Brandon Aiyuk's Arrest in California
Blake Corum

Remains an Elite Handcuff in Dynasty Leagues
Chris Godwin Jr.

Consistency the Key for Chris Godwin Jr. in Dynasty Leagues
David Montgomery

Can Managers Look to Sell High on David Montgomery This Year?
Malik Willis

a Low-Cost Dynasty Target in Miami?
CFB

Can Eric Singleton Jr. Fully Break Out at Third School?
CFB

Katin Houser Steps into QB1 Role for Illinois
CFB

Savion Hiter an Immediate Impact Freshman for Michigan
CFB

Isaiah Horton Set to Take Over KC Concepcion's Role
CFB

UCLA Transfer Karson Gordon Signs with Austin Peay
CFB

Will Muschamp Bringing New Intensity to Texas Practices
Gary Woodland

Brings Boom-or-Bust Potential to Memorial
Jordan Spieth

Still Searching for a Breakthrough
Alex Smalley

Brings Elite Form to Memorial Tournament
Justin Rose

Looks to Recapture Memorial Tournament Success
Cameron Young

Looks to Get Back to His Contending Ways at Murifield Village
Chris Gotterup

Needs to Find Fairways at Muirfield Village
Si Woo Kim

Looks to Stay Hot at Memorial Tournament
Matt Fitzpatrick

Positioned for Success at Muirfield Village
Jalen Chatfield

Records Two Assists in Tuesday's Loss
Keegan Bradley

Looking for Another Strong Finish at Muirfield
Nikolaj Ehlers

Nets Two Goals in Game 1 Loss to Golden Knights
Shea Theodore

Notches Three Points in Game 1 Win
Brayden McNabb

Sets Up Three Goals in Game 1 Win Over Hurricanes
Justin Thomas

is an Exciting Play This Week in Ohio
Brett Howden

Starts Finals With Multi-Point Effort
Scottie Scheffler

Looks to Win Memorial Tournament for Third Consecutive Year
Tomas Hertl

Scores Game-Winner in Finals Opener
Rory McIlroy

Looking for Better Performance at Muirfield Village
Drake Baldwin

Could Return During Braves Next Homestand
Garrett Crochet

Diagnosed With Low-Grade Lat Strain
Russell Henley

Coming to Ohio on the Heels of Latest Victory
Tommy Fleetwood

Looking for Better Iron Play at Memorial Tournament
Patrick Cantlay

Looks to Continue Dominance at Muirfield Village
Ludvig Aberg

a Great Fit for Muirfield Village
Isaiah Hartenstein

Hopeful to Stay with Oklahoma City
Luguentz Dort

Wants to Remain with Thunder
Mitchell Robinson

is Questionable for Game 1
Moussa Diabaté

Moussa Diabate Has Contract Guaranteed for 2026-2027 Season
Oso Ighodaro

Gets Guaranteed Contract for Next Season
NAS

Chris MacFarland Joins Predators as President and General Manager
VAN

Canucks Name Manny Malhotra as New Head Coach
Brendan Gallagher

to Leave Canadiens This Offseason
Patrik Laine

Looking Forward to Free Agency
Jeremy Lauzon

Returns to Action Tuesday
Zach Werenski

Wins 2025-26 Norris Trophy
Aaron Judge

Out on Tuesday With Rib/Shoulder Injury
Josh Hader

Set to Return from Injured List on Tuesday
CFB

SEC Coach Calls Buster Faulkner a "Home-Run Hire"
CFB

Auburn a Sleeper in the SEC Under Alex Golesh?
CFB

Noah Fifita Primed for Strong 2026 Campaign
CFB

Oregon Assistant Coach Charged with DUII, Reckless Driving
CFB

Tight End Nick Pollack Commits to Clemson
Akshay Bhatia

Needs the Driver to be True in Ohio
Aaron Rai

Primed to take on the Memorial Tournament
J.J. Spaun

Rebounded at Charles Schwab Challenge
Xander Schauffele

One to Watch This Week in Ohio
Elly De La Cruz

to Miss 2-4 Weeks of Action
Chase Burns

is Scratched Due to Illness
Deiveson Figueiredo

Suffers Second-Round Submission Loss
Song Yadong

Gets Second-Round Submission Win
Zhang Mingyang

Suffers Back-To-Back Losses
Alonzo Menifield

Gets Back In The Win Column
Tallison Teixeira

Suffers First-Round Knockout Loss
Sergei Pavlovich

Scores First-Round Knockout Win
Cameron Smotherman

Suffers Third Loss In A Row
Edwin Arroyo

Reds Promote Top Infield Prospect Edwin Arroyo, Viewed as Priority Pick Up Ahead of MLB Debut
Kai Asakura

Earns His First UFC Win
Elly De La Cruz

Placed on IL with Right Hamstring Tightness
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Christopher Bell

Finishes as the Runner-Up at Nashville
Chase Briscoe

Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Kyle Larson

Top-10 Streak at Nashville Ends after Late Flat Tire Spin
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF