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DraftKings CFB DFS Picks - Daily Fantasy College Football Advice for 10/6

Can't believe it's already week six of the college football season, but here we are. The benefit of being nearly halfway through the season is that we have a much clearer picture of which teams are good, and which of those are frauds we were fooled by in the earlier weeks of the 2018 season. The only downside to this week's 10 game slate is that there are more than a handful of potential blowout games.

Speaking of blowouts, that inclination comes directly from the Vegas lines I have been pouring over this week. The three games with the top projected points totals - which happen to be the only three with an over/under above 60 - all happen to have spreads of 20+ points. Yikes. That really limits my pool of "games I adore because of Vegas projections", but there are two that stick out as good targets. The Texas-Oklahoma game has an over/under of 60.5, with the Sooners favored by 7. And the second best game from this lens is the Iowa State at Oklahoma State matchup, with an over/under of 54.5 and the Cowboys favored by 9.5

In this article, I will be providing you with my daily fantasy college football lineup picks for DraftKings on 10/6/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @kpLuch.

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DraftKings DFS Quarterbacks

Kyler Murray - QB, vs Texas ($10,200)

There may be a few quarterbacks this week who have safer point floors than Murray - Will Grier and Dwayne Haskins, for instance - but I don't feel that any have the ceiling that Murray has. And this isn't a point chasing play. Yes, Murray went completely off last week thanks to six touchdowns through the air and rushing for another, but this is about matchup and the projected competitiveness of this game. Many of the top (priced) quarterbacks in play this weekend have cupcake matchups, and I'm afraid those offenses will be taking their collective feet off the gas pedal early - this shouldn't be the case in this storied rivalry. The game has one of the most attractive over/unders at 60.5, and a spread of just 7. What makes this more enticing is that the Sooner have the top offense in the S&P+ rankings, and they face a Texas team that ranks 80th on defense by those same standards. Led by Murray, the Sooner should be moving the ball well and chasing points for all four quarters.

Taylor Cornelius - QB, vs Iowa State ($8,400)

Cowboy quarterback Taylor Cornelius has played with serious consistency this year, only failing to reach his price implied point total once through five weeks of play. He has a moderate price tag for the production he's had, and I think this game environment raises his points floor and ceiling this week. As noted above, this is one of the most attractive games whilst viewing the slate from a Vegas perspective, albeit on a pretty ugly slate. As for the actual matchup itself, Iowa State is no slouch defensively, but there is a big enough discrepancy between their pass defense and run defense that I think there's an edge to be had here. The Cowboys do have a stud running back in Justice Hall, but the Cyclones have the talent up front in the box to keep him in check. As their pass defense is far inferior, I think this game script sets up well for Cornelius to fire 30+ passes and find success through the air.

Also Consider: Will Grier - QB, vs Kansas ($10,400)

 

DraftKings DFS Running Backs

J.K. Dobbins - RB, vs Indiana ($7,500)

Pound for pound (okay, dollar for dollar, rather) Dobbins is my favorite play in week six of college football daily fantasy. I love his floor, and I'm pretty enticed by his ceiling as well against the Hoosiers. In what appeared as a truer time share earlier in the season between Dobbins and Weber, Dobbins seems to have separated a bit and emeraged as the clear #1 (although, as you'll see in my Also Consider - I think Weber is a fine cash play plug thanks the matchup and price) and has received the lion's share of the carries in the past two weeks. This Indiana team actually ranks pretty well defensively, but they haven't seen a beast like the Buckeyes offense yet, and they, too, have a lopsided unit. Their defensive backfield is pretty talented, while their front seven is young and lost a lot of key guys from the year before. I think Dobbins is going to have his number called early and often en route to a big game.

Kennedy McKoy - RB, vs Kansas ($5,000)

A game with an incredibly high point total and a big spread? This has the makings of a blowout game that can flip a game script to "feed the running backs all second half to control the clock". I like McKoy as both a sleeper and a value play in week six. He's failed to meet salary based expectations only once, and as such I think he's a fairly safe cash play. He's been fed the rock at least 11 times in each of the last three weeks, and due to the game script switch I can see happening, I like him as a high ROI guy you can plug into tournament lineups as well.  The fact that Kansas has allowed an average of 177 yards per game on the ground makes him even more enticing.

Also Consider: Mike Weber - RB, vs Indiana ($5,900)

 

DraftKings DFS Wide Receivers

Marquise Brown - WR, vs Texas ($7,700)

The Texas Longhorn defense is without a doubt improved - but they still have a glaring weakness, and that's allowing big plays. Enter Marquise Brown, one of Kyler Murray's favorite targets and a big-time deep threat receiver. He's found the endzone at least once every week this season (save for the Army game), and he's eclipsed 130 yards receiving in three of five games. The Vegas projections for this game certainly help to elevate his status, and he should find some soft spots in this Longhorns secondary.

Whop Philyor - WR, at Ohio State ($3,700)

Philyo's status - he banged up his angle two weeks ago - is still not completely known, so this is a spot to keep an eye on. If he's able to go, however, I think he becomes an incredible value with a fairly high ceiling relative to his price. He's a dyanmic playmaker that the Hoosiers like to get the ball to in space, and he had a monster 13-catch, 138 yard performance against Michigan State in his last piece of action. The projected game script and score also make this matchup more enticing, as the Hoosiers will likely be forced to throw the ball often to keep pace with the Buckeyes. If Philyor is unable to go, Nick Westbrook is a fine cash option and Donovan Hale (both Hooosier receivers) have their respective floors raised a bit - but reserve Hale for tournament play only.

Also Consider: Jerry Jeudy - WR, at Arkansas ($6,900)

More NCAA Football Analysis

REAL-TIME FANTASY NEWS

Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Cam Skattebo

Dynasty Stock Rising Following NFL Draft
Kaleb Johnson

Logging First-Team Reps in OTAs
Evan Engram

Dynasty Value Fading After Production Decline in 2025
TreVeyon Henderson

Dynasty Outlook Clouded By Split Backfield in New England
Caleb Williams

' Dynasty Upside Remains Sky-High Entering 2026
Bijan Robinson

Is Bijan Robinson the No. 1 Overall Player in Dynasty Formats?
Woody Marks

Should Have Plenty of Opportunities to Catch Passes
Drew Allar

Working as QB4 in First OTA Session
Aaron Rodgers

Reports to Steelers Facilities on Monday
Alvin Kamara

Saints Remain Non-Committal on Alvin Kamara's Future
Chris Olave

Saints Continue to Work on Extension With Chris Olave
Parker Washington

a Sneaky Trade Target in Dynasty Leagues?
Melquizael Costa

Drops Decision At UFC Vegas 117
Jarquez Hunter

Can Jarquez Hunter's Dynasty Outlook Improve in Year 2?
Arnold Allen

Bounces Back
James Conner

Off the Dynasty Radar Entirely?
Elijah Arroyo

Will Elijah Arroyo Continue to Have Trouble Getting on the Field?
Daniel Santos

Suffers Second-Round TKO Loss
Tre Tucker

Not a Long-Term Solution in Dynasty Leagues
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jack Bech

a Dynasty Hold as New-Look Raiders Offense Takes Shape
Jaydon Blue

a Low-Value Dynasty Stash Until Depth Charts are Settled
Makai Lemon

a Top-Five Pick in Dynasty Rookie Drafts
George Kittle

a Dynasty Buy with League-Winning Potential
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Chris Rodriguez Jr.

a Dynasty Sleeper with High Touchdown Potential
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Donovan Mitchell

Guides Cavaliers Into East Finals
Sam Malinski

Practices Fully Sunday
Jarrett Allen

Scores 23 Points in Cavs' Game 7 Rout of Pistons
Josh Manson

Rejoins Practice
Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Bones Hyland

Wants to Stay in Minnesota
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF