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Break The Slate: NFL DFS DraftKings Lineup Picks - Week 5

The top daily fantasy football lineup picks for DraftKings in Week 5 of 2019. Joe Nicely's NFL DFS analysis and sleepers for building optimal DFS rosters.

Hello again RotoBallers and NFL DFS fans! Thanks for joining me here at Break The Slate, a weekly article in which we try to pinpoint the best DraftKings plays available on the main slate. Unfortunately, Week 4 didn't exactly go as planned and was just one of those strange weeks that we see a couple of times a year in the NFL.

These DraftKings lineup recommendations are based on matchups, projected ownership, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great plays available, so read on to find out which players are the best for Week 5.

Good luck with your DraftKings DFS lineups, lets Break The Slate together!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 5 Picks

Jameis Winston - TB @ NO ($6,200)

All the preseason love that was going Jameis Winston's way seemed ridiculous after a disastrous opening week performance against the 49ers, but maybe we were right all along. The Tampa QB has certainly picked up the pace in his last two starts, throwing for a combined 765 yards and seven TDs against the Giants and Rams. The matchup is a bit tougher this week, as he heads to New Orleans for a divisional road game, but the Saints - despite shutting down Dak Prescott last Sunday night - aren't a matchup to fear, as they've allowed the third-most DraftKings points in the NFL to opposing QBs. Fantasy players were excited about what Winston might do under the tutelage of new Bucs HC Bruce Arians and things finally appear to be clicking. Winston has thrown for over 1,100 yards and is tied for the second-most TD passes in the NFL at nine - all this despite a sluggish start to the season. I look for things to continue rolling against the Saints this week.

Matt Ryan - ATL @ HOU ($5,900)

I grew up loving college football, so I don't really have a lifelong allegiance to an NFL team, but the Falcons have definitely been my 'favorite' NFL team for my adult life. Personal biases aside, I will continue to die on the "Matt Ryan is the most overlooked and undervalued DFS QB in the NFL" hill. This will probably be the case again this week, as I expect most of the DFS attention in this matchup to be on the other QB in this game - Deshaun Watson. Despite Atlanta's struggles as a team, Ryan is off to a blistering start in 2019, averaging 23.7 DK points per game. He's thrown for over 300 yards in every game this season and leads the NFL with 176 pass attempts. He draws a matchup against a Texans unit that has relinquished over 1,100 yards and 90 DK points to opposing QBs this year, in a game in which Houston should have no trouble shutting down Atlanta's non-existent run game and carries definite shootout potential.

 

DraftKings DFS Running Backs - Week 5 Picks

Dalvin Cook - MIN @ NYG ($8,400)

You won't find many surprises in this article at the RB position this week. I like grabbing as much floor as possible at running back, and there are several quality backs in great spots this week, so barring any breaking injury news I'll be leaning in a pretty vanilla direction at RB.

Let's kick things off with one of the most impressive running backs of the season, Minnesota's Dalvin Cook. We've always known the talent was there with Cook, but the biggest obstacle in his injury-plagued career has been staying on the field. He's been healthy this year and this run-first Vikings offense is taking full advantage of his ability. Cook sits one yard behind Christian McCaffrey for the most rushing yards in the NFL at 410. He's ran for over 100 yards in three of Minny's four games. This week's matchup against the New York Giants isn't as amazing as it appears at first glance (New York ranks middle of the pack in yards and DK points allowed to opposing RBs), but it is certainly a very strong spot for Cook.

Ezekiel Elliott - GB @ DAL ($8,300)

For all the pearl clutching that his holdout caused, the whole Ezekiel Elliott contract thing turned out to be nothing major. Zeke has played and been low-key solid, going for over 100 yards rushing in two of the Cowboys four games. He was practically shut down on the ground in a defensive struggle against New Orleans last Sunday night, but salvaged his numbers with a TD on the ground and six catches on seven targets for 30 yards. That's the thing about Elliott...it'll seem as though he's having a very ho-hum game and next thing you know he has 18 DK points. Obviously we want more than that at this price, but the point is that his floor is so stable that it's hard for him to have a truly bad game. That said, I'm focusing more on Elliott's ceiling this week against a Packers Defense that has been routinely shredded on the ground and has allowed the third-most DK points in the NFL to opposing running backs.

David Johnson - ARI @ CIN ($7,500)

Even though he's up to $7.5k, David Johnson might just be the best value on the board at the RB position this week. Despite not breaking 100 yards rushing in a single game this season, DJ has still managed to be effective and average 18.5 DK points per game. He's doing most of his damage as a receiver out of the backfield and gets a smash spot against a Bengals Defense that has allowed 285 receiving yards to opposing running backs, the most in the NFL. Cincy is also dead last in the league in DK points allowed to the RB spot at 156.44. In this high-volume Arizona offense, DJ will have plenty of opportunities to gash the Bengals both through the air and on the ground in Week 5, and will see a little bit of an increase in usage due to Christian Kirk's absence. This spot is beautiful and makes Johnson my favorite RB play of the week.

 

DraftKings DFS Wide Receivers - Week 5 Picks

Julio Jones - ATL @ HOU ($7,700)

The best receiver in the league against a rookie cornerback probably won't equal a great outcome for the home team in this one. Julio Jones is once again having a superstar-caliber season for the Falcons. He's went over 100 yards in two of Atlanta's four games and will see lots of Houston's rookie CB Lonnie Johnson Jr. this week, who currently has a PFF grade of 32.5, the third-worst grade of cornerbacks in the NFL this season. As we touched on when discussing Matt Ryan earlier in this article, the Falcons are one of the most pass-happy teams in the NFL and should once again be forced to the air quickly in this one. Jones is averaging a shade over nine targets per game and I wouldn't be a surprised to see him get over double digits looks this week.

Michael Thomas - TB @ NO ($6,600)

I very rarely roster Michael Thomas, so it feels a little weird that I'm interested in him with Drew Brees out of the lineup, but I'm really intrigued by Thomas' reduced price tag. At $6.6k we're getting a player that is still the unquestioned alpha in the New Orleans receiving corps and seeing basically 1/3rd of the teams total targets. Bridgewater is certainly no Brees, but Thomas is usually his first look and he's received 16 targets in Teddy B's two full games as the starter. He squares off against a Bucs defense that is improved, but still very beatable in the pass game and has yielded the fourth-most DK points in the league to opposing WRs. Bridgewater no doubt hampers Thomas' chances of breaking the slate, but we should have no problem seeing a great return on our $6.6k investment.

Auden Tate - ARI @ CIN ($3,500)

With John Ross headed to IR, there's practically a big neon arrow pointing to Auden Tate that says: "Play Me", so the Bengals wideout will no doubt be a popular option here. However, like Seattle's Will Dissly last week, he's chalky because he's a very strong play. Value is tough to come by on this slate and Tate is in a great spot to offer salary relief when constructing Week 5 rosters. I continue to circle the Arizona Cardinals anytime they are on the slate due to the amount of plays they both run and allow each week. While Ross is now out of the Cincy passing attack, Tate had actually already been integrated into the Bengals scheme, as he received 10 targets while playing 88% of Cincy's offensive snaps in Week 3 and getting six targets and being on the field for over 91% of snaps last week. He should continue to be heavily involved against the Cards.

 

DraftKings DFS Tight Ends - Week 5 Picks

Tyler Eifert- ARI @ CIN ($3,300)

Eifert is simply a flowchart play this week. What's a flowchart play? It goes something like this...
#1. Does Tyler Eifert play tight end in the NFL? If yes, go to question #2.
#2. Is Tyler Eifert's team playing the Arizona Cardinals this week? If yes, roster him on DraftKings.

Dawson Knox - BUF @ TEN ($3,100)

If we're going to afford all these high-priced RBs in Week 5, we're gonna need to save salary somewhere. Buffalo's Dawson Knox is worth a look if you want to pivot from Tyler Eifert and are comfortable with a semi-punt at the TE position. His viability rests on a couple of injuries though...you'll want to keep an eye on Tyler Kroft's status, as well as Josh Allen's. If Kroft plays, Knox is totally off the board. If Allen sits, Knox becomes much riskier with Matt Barkley at QB. The rookie TE is athletic and has made some noise in Buffalo's last two games in which he's caught six passes for 125 yards and a TD. This Titans Defense is quickly showing themselves to be susceptible to the TE position, as they've allowed three TDs, 239 yards, and 65.90 DK points to opposing TEs this season.

 

DraftKings DFS Defenses - Week 5 Picks

New England Patriots - NE @ WAS ($4,300)

I've been riding this Patriots Defense this year and I see no reason (outside of salary considerations) to hop off now. The Pats have been wreaking havoc on opposing offenses this season and we can expect more of the same this week if Washington rolls out rookie QB Dwayne Haskins again or career backup Colt McCoy. I don't know if I'll be able to lock the Patriots in due to the lack of value on this slate, but I'll try my best to get up to New England as often as possible when constructing lineups.

Carolina Panthers - JAX @ CAR ($2.600)

This isn't a 'smash' spot at first glance, but I like the quality that we are getting with the Panthers at this price. The Carolina defense has stepped up in the absence of Cam Newton, allowing just 30 total points over their last two games, while creating four turnovers and racking up a massive 14 sacks. Gardner Minshew has played well since stepping into the starting role for Jacksonville, but he is still a rookie that's facing an improving defense on the road.

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Dean Wade

Returns to Starting Unit Tuesday
OG Anunoby

Starting on Tuesday
Tobias Harris

May Remain in Motown
Jalen Duren

Pistons Eager to Keep Jalen Duren
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Dallas Mavericks

Jason Kidd Fired as Mavericks Head Coach
De'Aaron Fox

Officially Listed as Questionable for Game 2 Against Thunder
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Tank Bigsby

Is Tank Bigsby a Worthy Dynasty Stash Entering 2026?
Hunter Henry

Profiles as a Dynasty Sell-High Candidate Entering 2026
Gerrit Cole

to Make Season Debut on Friday Against Rays
Matthew Golden

Can Matthew Golden Re-Establish His Dynasty Value in 2026?
Jalen Coker

a Prime Buy-Low Dynasty Target
Dak Prescott

Remains a High-Floor Dynasty Quarterback
CeeDee Lamb

Is CeeDee Lamb's Dynasty Value Poised to Rise in 2026?
Keon Coleman

Joe Brady Likes What he's Seen From Keon Coleman
Deshaun Watson

Hitting it Off With Todd Monken?
Jacoby Brissett

Not Present for First OTA Practice
Tua Tagovailoa

Michael Penix Jr. Splitting First-Team Reps at OTAs
Rashee Rice

Tests Positive for Marijuana, Violating his Probation
Cam Skattebo

Says he'll be Ready for Week 1
De'Von Achane

Present for Start of OTAs This Week
Malik Washington

an Affordable Trade Target in Dynasty Leagues
Patrick Mahomes

Is Patrick Mahomes Still a Top-Five Dynasty Quarterback?
Michael Trigg

Is There a Spot for Michael Trigg in Dallas?
Seth McGowan

in the Mix for Playing Time as a Rookie?
Audric Estimé

Audric Estime Droppable in Dynasty Leagues?
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
Kyren Williams

Have Timeshare Concerns Sunk Kyren Williams' Dynasty Value Too Low?
Ja'Marr Chase

Is Ja'Marr Chase the Most Valuable Player in Dynasty?
Javonte Williams

' Unusual Career Path Has Left Him Undervalued in Dynasty Leagues
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Victor Wembanyama

Dominates Game 1 Against Thunder
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Sam Malinski

Practices Fully Sunday
Josh Manson

Rejoins Practice
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF