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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

REAL-TIME FANTASY NEWS

Nathan MacKinnon

Will Suit Up Tuesday
Jerome Ford

Is it Time for Dynasty Managers to Drop Jerome Ford?
John Metchie III

Poised for Breakout Season with New Team in 2026?
Jalen Milroe

Is Jalen Milroe Still Worth Stashing in Dynasty Formats Entering 2026?
Kyle Pitts Sr.

Is Kyle Pitts Sr. a Dynasty Sell-High Candidate Coming Off Breakout Season?
Nico Collins

Agrees to Contract Adjustment with Texans
Chris Brooks

Carries Buy-Low Dynasty Appeal into 2026
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
NFL

NFL Unlikely to Expand to 18 Regular-Season Games by 2027
Sahith Theegala

Searching For Swing at Charles Schwab Challenge
Lamar Jackson

in Attendance at OTAs This Week
Bucky Irving

Expected Back in the Summer or Fall
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
Jalen Tolbert

Does Jalen Tolbert Have Short-Term Dynasty Appeal?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Travis Etienne Jr.

Is Travis Etienne Jr. Still a Dynasty RB1 Following Change of Scenery?
Breece Hall

Extension Solidifies His Dynasty Outlook
Devin Singletary

Faces a Difficult Path to Relevance
Jordan Whittington

Does Jordan Whittington Have Any Dynasty Value Left?
Caleb Williams

Bears Want Caleb Williams to "Do Less"
Xavier Worthy

Has Xavier Worthy Become a Post-Hype Dynasty Sleeper?
DeMario Douglas

A Playing-Time Blockage Could Make DeMario Douglas a Dynasty Drop Candidate
Elijah Sarratt

Can Elijah Sarratt Emerge From the Middle Rounds of Dynasty Rookie Drafts?
Antonio Williams

a Borderline First-Round Pick in Dynasty Rookie Drafts
Joe Flacco

a Low-Cost Dynasty Handcuff with Immense Upside
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Dont'e Thornton Jr.

Falling Out of Favor Already in Dynasty Formats?
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Ajay Mitchell

is Ruled Out for Game 5
Jalen Williams

is Tagged as Questionable for Game 5
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
De'Aaron Fox

Records Double-Double as Spurs Even Series
Victor Wembanyama

Sets Tone Early as Spurs Force a Pivotal Game 5
Jamal Murray

Earns First Career All-NBA Selection
Kevin Durant

Becomes First Player to Make All-NBA Team With Five Franchises
Shai Gilgeous-Alexander

Victor Wembanyama Lead All-NBA First Team
Taylor Hall

Enjoying Life in Carolina
Mark Stone

Returns to Action Sunday
Cale Makar

Rejoins Avalanche Lineup Sunday
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
Phillip Danault

Extends Point Streak to Three Games
Josh Anderson

Nets Two Goals in Painful Loss
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF