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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Nick Scott

Panthers Re-Sign Safety Nick Scott to One-Year Deal
Nico Hischier

has Four-Point Performance on Saturday
Kene Nwangwu

Jets Re-Sign Kene Nwangwu
Seiya Suzuki

Leaves WBC Game on Saturday With Right-Knee Discomfort
Macklin Celebrini

Continues to Dominate With Three Points
Anze Kopitar

Becomes All-Time Leading Scorer for Kings
Linus Ullmark

Posts Shutout Against Ducks
Travis Hunter

Is Travis Hunter Now an IDP-Only Asset?
Blake Corum

Does Blake Corum Have Standalone Flex Value?
Mo Alie-Cox

Re-Signing with Colts
Jaxson Dart

to Benefit from Improved Weaponry in Year 2
Darnell Mooney

Signing with Giants on One-Year Deal
Zach Neto

is Removed After Suffering Hand Injury
TB

Nicholas Paul Rejoins Lightning Lineup
Cole Caufield

Cleared to Play Saturday
Alex Tuch

Set to Return Saturday
Bobby Brink

Remains Out Saturday
J.T. Miller

Returns to Action Saturday
Joe Ryan

Won't Pitch in the World Baseball Classic
Courtland Sutton

Will Courtland Sutton Lose Targets to Younger Teammates?
Rashee Rice

Looking to Return to Rookie Form?
Omarion Hampton

Has High Upside with New Offensive Coordinator
Trey Lance

Returns to the Chargers on a One-Year Deal
A.J. Brown

Rams Out on A.J. Brown, Trade to Patriots Likely?
Calvin Ridley

Restructures Deal with Titans
Jonathan Taylor

Is Jonathan Taylor Being Undervalued in Dynasty?
Tony Pollard

Can Tony Pollard Keep the RB1 Spot for Titans?
David Montgomery

Has Contract Updated by Texans
Zack Wheeler

Throws First Live BP Session on Saturday
Chris Godwin Jr.

Can Chris Godwin Jr. be the Buccaneers' WR1?
LeQuint Allen Jr.

Can LeQuint Allen Jr. Emerge as the Primary Receiving Back in Jacksonville?
Isaiah Davis

Appears Buried on the Jets Running Back Depth Chart
Merrill Kelly

Expected to Open Season on the Injured List
Christian Kirk

Dynasty Value is Fading Heading into 2026
Anthony Richardson Sr.

Packers Interested in Acquiring Anthony Richardson Sr.?
Kevin Gausman

Named Toronto's Opening Day Starter
Kyle Stowers

Back in Grapefruit League Lineup
Kevin Porter Jr.

Questionable Against Hawks
Devin Carter

Out Saturday Against Clippers
Russell Westbrook

Set to Return Against Clippers
Derrick White

Expected to Play Saturday Against Wizards
Michael Porter Jr.

Likely to Miss Second Straight Game
Nicolas Claxton

to Rest Saturday Against Philadelphia
Ace Bailey

Leaves Friday's Game Early with Concussion
Radko Gudas

Handed a Five-Game Suspension
Auston Matthews

to Miss Rest of Season
Emil Heineman

Scores Twice Against the Kings
Joel Hofer

Shuts Down the Oilers
Giannis Antetokounmpo

Could Miss Saturday's Game Vs. Hawks
Keegan Murray

to Be Re-Evaluated in Two Weeks
Aaron Gordon

Expected Back Saturday Vs. Lakers
Jamal Murray

Expected to Suit Up Saturday
Collin Sexton

to Miss Third Straight Game
Jalen Smith

is Ruled Out for Friday's Game
Robert Williams III

is Unavailable for Friday's Contest
Draymond Green

is Downgraded to Out on Friday
De'Anthony Melton

to Play on Friday
Ayo Dosunmu

is Cleared for Friday's Game
Anthony Edwards

is Available on Friday
Norman Powell

is Tagged as Questionable for Saturday
Victor Wembanyama

Questionable Saturday Vs. Hornets
Andrew Wiggins

to Miss Fifth Straight Game
Francisco Lindor

Takes Full Batting Practice on Friday
Brandon Woodruff

Still TBD for Opening Day
Trevor Rogers

to Start on Opening Day for Orioles
Kevin Vallejos

Looks To Remain Undefeated In The UFC
Josh Emmett

In Dire Need Of Victory
Gillian Robertson

A Favorite At UFC Vegas 114
Amanda Lemos

Set For Co-Main Event
Oumar Sy

Looks To Win Back-To-Back Fights
Ion Cutelaba

Looks To Get Back In The Win Column
Nathan MacKinnon

Racks Up Four Points in Victory Over Kraken
Alexis Lafrenière

Alexis Lafreniere Stays Hot in Winnipeg
Semyon Varlamov

Won't Return This Season
Alexander Romanov

Could Return for Playoffs
Declan Carlile

Hurt on Thursday Night
Wyatt Kaiser

Sustains Upper-Body Injury Thursday
Erik Gudbranson

Could Be an Option Saturday
Auston Matthews

Exits Game With Injury
Blake Snell

Around Six Weeks From Being Fully Built Up
Zack Wheeler

to Face Hitters in Live Batting Practice on Saturday
Gerrit Cole

Could Pitch in a Spring Game Next Week
Matthew Boyd

Named the Cubs' Opening Day Starter
Francisco Lindor

Remains on Schedule for Opening Day
Bryce Miller

Shuts Down Bullpen Due to More Oblique Discomfort
Zac Gallen

Named Arizona's Opening Day Starter
Kyle Teel

Could Miss 4-6 Weeks With Hamstring Strain
Hideki Matsuyama

Brings Strong Course History to TPC Sawgrass
Josh Hader

to Start the Year on the Injured List
Adam Scott

in Strong Form Ahead of The Players
Kyle Teel

Exits Tuesday's Game With Hamstring Injury
Rickie Fowler

on Quite the Run Heading to TPC Sawgrass
Sepp Straka

Needs to Forget What Happened Sunday at Bay Hill
Jordan Spieth

an Enigma Heading to The Players Championship
Justin Rose

Trying to Pick Up the Pieces in Florida
Maverick McNealy

Bounces Back at Arnold Palmer Invitational
Brooks Koepka

Continues His Florida Swing With Some Momentum
Nicolai Hojgaard

in Strong Form Ahead of The Players
Robert MacIntyre

a Volatile Option at The Players
Matt Fitzpatrick

Looks to Return to Top Form at The Players
Sam Burns

a High-Risk, High-Reward Option at The Players
Keegan Bradley

Hard to Trust at The Players
Xander Schauffele

Rounding into Form Heading to Players Championship
Rory McIlroy

Set to Return at Players Championship to Defend Title
Jake Knapp

Set to Return at Players Championship
Viktor Hovland

Continues Strong Start to 2026 Season
Rasmus Hojgaard

Looking for Bounce-Back at Players Championship
Tommy Fleetwood

Will Need to Find Putter to Compete at Players Championship
Akshay Bhatia

Continues Improving Heading to Players Championship
Merrill Kelly

Set to Make Spring Training Debut on Friday
Justin Thomas

Continues Competitive Return at The Players Championship
Max Holloway

Drops Decision At UFC 326
Charles Oliveira

Becomes The New BMF Champion
Caio Borralho

Bounces Back
Reinier de Ridder

Reinier De Ridder Loses Back-To-Back Fights
Rob Font

Gets Dominated
Raul Rosas Jr.

Extends His Win Streak
Michael Johnson

Suffers Second-Round Knockout Loss
Drew Dober

Knocks Out Michael Johnson
Ryan Blaney

Earns his Second Consecutive Phoenix Cup Series Win
Christopher Bell

Falls Short of Victory Despite Dominating at Phoenix
Kyle Larson

Earns Hard-Fought Finish of Third at Phoenix
Denny Hamlin

Quietly Gains Another Top-Five Finish at Phoenix
Joey Logano

Crashes out at Phoenix Despite Strong Run
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF