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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Tanner Bibee

Shoulder Issue Not Considered Serious
NFL

Nicholas Singleton Relying on Traits Over Tape for Early Draft Capital
J.K. Dobbins

Positioned for Another Strong Season in Denver
NFL

Malachi Fields' Draft Stock Looks to Be Sliding
Barrett Hayton

Out Week-to-Week
Travis Etienne Jr.

Should See Feature Role Following Big-Market Deal
Tony DeAngelo

to Miss 1-2 Weeks
Sam Steel

Makes Early Exit Against Islanders
NFL

Ty Simpson Garnering First-Round Buzz
Damon Severson

Exits With Upper-Body Injury Thursday
Joe Pyfer

Set For UFC Seattle Main Event
Yaroslav Askarov

Suffers New Injury Blow
Israel Adesanya

Returns At UFC Seattle
Evan Rodrigues

Breaks Finger Thursday
Maycee Barber

Looks To Extend Her Win Streak To Eight
Sidney Crosby

Suffers Lower-Body Injury Thursday
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Tyler Allgeier

Joins a Crowded Backfield in Arizona
Kenneth Gainwell

Can Kenneth Gainwell Maintain PPR Prowess in New Digs in Tampa?
Bilal Coulibaly

Could Miss Friday's Game
Jakub Dobes

Defeats the Blue Jackets on Thursday
NFL

Zachariah Branch a Day 2 Receiver With Game-Changing Speed
Alexandre Sarr

Could Miss Third Straight Game
Cade Otton

Quietly Due for a Bigger Workload?
Noah Cates

has Two-Point Game on Thursday
Tetairoa McMillan

Headed for a Big Year 2?
T.J. Hockenson

Still Trending Down in Dynasty Leagues
Jordan Love

Still Not Back in the QB1 Tier
Kyle Filipowski

Expected Back After Illness
Terrance Ferguson

a Sneaky Dynasty Buy?
Isaiah Collier

to Miss Fifth Straight Game
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Deandre Ayton

Off Injury Report Friday
Luka Dončić

Luka Doncic Questionable Against Brooklyn
Ty Jerome

to Miss Second Straight Game
Anfernee Simons

Unlikely to Play Friday
Jarrett Allen

Iffy for Miami Game
Aaron Nesmith

Expected to Play Friday
Neemias Queta

Questionable for Friday
Derrick White

Iffy Against Hawks
Kevin McGonigle

has Four Hits in Impressive MLB Debut
Killian Hayes

is Returning on Thursday
Tobias Harris

is Active on Thursday
Ausar Thompson

is Cleared for Thursday's Game
Jalen Duren

is Upgraded to Available
Nico Hoerner

Cubs Agree to Six-Year Deal With Nico Hoerner
Trey Murphy III

Ruled Out for Thursday
Precious Achiuwa

is Available on Thursday
Caris LeVert

is Ruled Out for Thursday
Jacob Misiorowski

Shows Off his High-Strikeout Upside in Opening Day Win
Marcus Foligno

Available Against Panthers
Jaylen Brown

Considered Questionable for Friday
Tony DeAngelo

Unavailable Thursday
Anthony Mantha

Good to Go Thursday
Paul Skenes

Greeted Harshly by Mets on Opening Day
Thomas Chabot

Out 4-8 Weeks After Surgery
Jalen Suggs

Available on Thursday
Robert Thomas

Sits Out Thursday's Action
Tyler Toffoli

a Game-Time Call Thursday
Artturi Lehkonen

Returns to Action Thursday
Brandon Lowe

Hits Two Home Runs on Opening Day
Buffalo Bills

Bills Sign Receiver Trent Sherfield
Ketel Marte

Active, Leading Off on Opening Day
Tyler Goodson

Falcons Sign Tyler Goodson for Running Back Depth
Myles Garrett

Browns Won't Trade Myles Garrett
Kevin McGonigle

Batting Sixth in MLB Debut
Jeremy Peña

Jeremy Pena Not in the Lineup on Opening Day
Jonathan Greenard

Colts Interested in Jonathan Greenard
JJ Wetherholt

Batting Leadoff in MLB Debut
Micah Parsons

Expected to Miss First Three or Four Games of 2026
Breece Hall

Still a Chance Breece Hall Plays 2026 on Franchise Tag
Myles Garrett

Browns Modify Myles Garrett's Contract
Kyle Pitts Sr.

Remains a Risky Tight End Option Despite 2025 Breakout
Jackson Chourio

Placed on Injured List with Fractured Hand
Francisco Lindor

Officially Starting on Opening Day
Mika Zibanejad

Pots Two Goals Versus Toronto
Pavel Zacha

Adds Two More Points Against Buffalo
Nicolas Roy

to Be Out For "a Little Bit"
Anton Lundell

Likely Out for Rest of Regular Season
Anthony Mantha

Day-to-Day With Lower-Body Injury
Sean Murphy

Lands on 10-Day Injured List
Bryce Miller

Placed on 15-Day Injured List With Oblique Strain
Lars Nootbaar

Will Begin the Season on 60-Day Injured List
Jackson Holliday

Placed on 10-Day Injured List
Jeremy Peña

Jeremy Pena on the Astros Opening Day Roster
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Scottie Scheffler

Withdraws From Texas Children's Houston Open
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Kurt Kitayama

Poised to Bounce Back at the Houston Open
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Tyler Reddick

the Clear Favorite at Darlington
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF