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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Tanner Bibee

to Start on Tuesday Against Dodgers
Caleb Martin

Remains Sidelined Monday
Olivier-Maxence Prosper

to Miss Monday's Game
Marvin Bagley III

Won't Play Vs. Minnesota
Davante Adams

Expected to Stay With Rams
Daniel Gafford

Cleared to Play Monday
Walter Clayton Jr.

to Suit Up on Monday
Ausar Thompson

is Cleared for Monday's Game
P.J. Washington

Naji Marshall Ruled Out Monday
Jordan Addison

Vikings Picking Up Jordan Addison's Fifth-Year Option
Jalen Duren

to Sit Out on Monday
Anthony Edwards

Set to Return Monday
Nick Richards

to Miss Third Straight Game
Guerschon Yabusele

is Active on Monday
Grayson Allen

is Ruled Out for Monday
Jock Landale

Won't Play Monday
Ron Harper Jr.

Unavailable Against Hawks
Neemias Queta

Ruled Out Monday
Derrick White

Slated to Suit Up Against Hawks
Aliaksei Protas

Won't Play Tuesday
Jaden Ivey

Waived on Monday
Pavel Mintyukov

Returns to Action Monday
Radko Gudas

Ready to Face Maple Leafs
John Klingberg

to Remain Sidelined Monday
Jalen Williams

Ruled Out on Monday
Aleksander Barkov

to Remain Out Until End of Season
Jaylen Brown

Set to Suit Up Monday
Evgeni Malkin

Misses Fourth Consecutive Game
Sidney Crosby

a Game-Time Decision Monday
Jayson Tatum

Sidelined on Monday
Matt McCarty

Seeking to Play into the Weekend in San Antonio
Brian Harman

Looking to Continue Form From The Players Championship
Bucky Irving

Could See Reduced Workload in 2026 and Beyond
Kenneth Walker III

Could See Major Workload Increase in Kansas City
Steven Fisk

Attempting to String Better Rounds Together at San Antonio
Emeka Egbuka

Has WR1 Upside in Dynasty Formats
Bo Nix

"Ahead of Schedule" in Recovery From Ankle Surgery
Luke Clanton

Still Having Rough Time Contending at Events
Cooper Kupp

Dynasty Value is Fading Quickly
Jaylen Warren

Production Upside is Limited in Pittsburgh
Kirk Cousins

an Option for Rams as Backup Quarterback?
George Pickens

Cowboys Not Worried About George Pickens' Offseason Participation
Dalton Kincaid

Bills Pick Up Dalton Kincaid's Fifth-Year Option
Max Homa

Looks to Get Back on Track at Valero Texas Open
Russell Henley

Continues Blistering Start to 2026 Season
Tommy Fleetwood

Returns to Valero Texas Open
Daniel Berger

Returns to Action For Valero Texas Open
Chase Elliott

Takes Advantage of Pit Strategies for Second Career Martinsville Win
Denny Hamlin

Dominates but Finishes Second at Martinsville
Joey Logano

Bounces Back with Third-Place Finish at Martinsville
Ty Gibbs

Gains his Fourth Top-Five Finish of the Season at Martinsville
William Byron

Scores Another Top-Five Finish at Martinsville
Christian McCaffrey

49ers Looking to Spell Christian McCaffrey More in 2026?
Brandon Aiyuk

49ers in No Rush on Brandon Aiyuk Situation
Michael Penix Jr.

Falcons Don't Want to Rush Michael Penix Jr.'s Rehab
A.J. Brown

is a "Member" of the Eagles
Jonathon Brooks

Panthers Expect Jonathon Brooks to be Ready for OTAs and Minicamp
Alvin Kamara

Saints Going Through "Offseason Process" With Alvin Kamara
Alec Pierce

Can Alec Pierce Perform Like One of the Highest-Paid Receivers in the League?
Michael Pittman Jr.

a Buy-Low Candidate Following Post-Trade Dip
Rhamondre Stevenson

Should Still See Volume in Shared Backfield
NFL

Skyler Bell Hype Warrants Cautious Optimism
Jack Hughes

Amasses Four Points Against Blackhawks
Viktor Arvidsson

Plays Key Role in Comeback Victory
Lane Hutson

Celebrates New Assists Record Sunday
Adam Fox

Collects Two Points in Sunday's Win
Jake Guentzel

Leads Lightning Offense Sunday
Mathieu Olivier

Exits Early With Upper-Body Injury
Michael Bunting

Suffers Lower-Body Injury Sunday
Joe Pyfer

Extends His Winning Streak
Israel Adesanya

Loses Fourth Consecutive Fight
Nick Suzuki

Collects Three Points Against Hurricanes
Maycee Barber

Suffers Her First Knockout Loss
Frank Nazar

Scores Twice on Sunday
Alexa Grasso

Scores Highlight-Reel Knockout
Niko Price

Retires After UFC Seattle Loss
Keyonte George

Isaiah Collier Still Out Monday
Michael Chiesa

Victorious In His Retirement Fight
Julian Erosa

Suffers First-Round Knockout Loss
Lerryan Douglas

Scores First-Round Knockout Win In His UFC Debut
Alex Bregman

Clobbers First Two Homers in Sunday's Loss at Wrigley
Yandy Díaz

Yandy Diaz Records Five Hits, Drives in Four in Win Over Cardinals
Jeremy Swayman

Remains in Bruins Crease Sunday
TB

Nicholas Paul Available Against Predators
Nikita Kucherov

Remains Out Sunday
Mason Lohrei

Unavailable Sunday
Dmitri Voronkov

Considered Week-to-Week
Kyle Larson

Is Likely to Pay Off for DFS at Martinsville
Christopher Bell

Could Have Another Top-10 Performance At Martinsville
William Byron

Is A Threat to Win Again at Martinsville
Chase Elliott

is A Solid DFS Option for Martinsville Lineups
Chase Briscoe

has Plenty of Upside for DFS Lineups at Martinsville
Carlos Estévez

Carlos Estevez Unlikely to See High-Leverage Opportunities in Near Future
Jacob deGrom

Feels "Much Better," Hopeful he Can Start This Week
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Martinsville?
Ryan Preece

Is A Solid DFS Option for Martinsville Lineups
Josh Berry

Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
Carson Hocevar

May be Too Inconsistent to Start in Martinsville DFS Lineups
Austin Cindric

Is Austin Cindric Worth Rostering for DFS At Martinsville?
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
Joey Logano

Will Be Strong at Martinsville
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
Jeferson Quero

Brewers Calling Up Catching Prospect Jeferson Quero
Deyvison De Los Santos

Marlins Promote Deyvison De Los Santos to Major Leagues
Shea Langeliers

Hits Two Home Runs on Opening Day
Kevin Gausman

Picks Up No-Decision But Strikes Out 11 on Opening Day
Tanner Bibee

Day-to-Day, Could Make his Next Start
Shane Baz

Orioles Agree to Five-Year Extension
Jeremy Peña

Jeremy Pena Making Season Debut on Friday Against Angels
Tiger Woods

Involved In Rollover Car Crash
Tanner Bibee

Shoulder Issue Not Considered Serious
Joe Pyfer

Set For UFC Seattle Main Event
Israel Adesanya

Returns At UFC Seattle
Maycee Barber

Looks To Extend Her Win Streak To Eight
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF