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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Si Woo Kim

Looks to Continue Incredible Run at Torrey Pines
Jason Day

Has a Good Chance to Keep Momentum Going at FIO
Keegan Bradley

has Good Course History at Torrey Pines
Cam Thomas

Will Be Available Tuesday in Phoenix
Billy Horschel

Isn't a Great DFS Option at Torrey Pines
Malik Monk

Ruled Out on Tuesday
Zach LaVine

Will Not Play Tuesday in New York
Aaron Rodgers

Mike McCarthy Says he Wants Aaron Rodgers to Return
Bilal Coulibaly

Ready to Return to Action Against Portland
Deni Avdija

Draws Another Questionable Tag on Tuesday
Jusuf Nurkić

Jusuf Nurkic Will Not Play Tuesday Against Clippers
Lauri Markkanen

Available Tuesday Night
Will Zalatoris

Has a Shot to Challenge at the Farmers Insurance Open
Adam Scott

Can Continue Hot Start to 2026 Season at Farmers Insurance Open
Keith Mitchell

Hoping For a Strong Finish at Farmers Insurance Open
Hideki Matsuyama

Looks to Continue Strong Start at Farmers Insurance Open
Tom Hoge

Can Continue Hot Start to 2026 Season at Farmers Insurance Open
Harris English

Has a Chance to Repeat as Winner at the Farmers Insurance Open
Patrick Cantlay

Continues Playing Well and Can Compete at Farmers Insurance Open
Ludvig Aberg

Looks to Bounce Back After Withdrawing at American Express
Drake Maye

Expected to be Fine for Super Bowl
Xander Schauffele

is The Best Fit at Torrey Pines This Week
Tennessee Titans

Titans Set to Hire Brian Daboll as New Offensive Coordinator
Justin Rose

Making 16th Start at Farmers Insurance Open
Maverick McNealy

is a Smart Play at Torrey Pines
Buffalo Bills

Bills Promote Joe Brady to Head Coach
Brooks Koepka

Making PGA Tour Return at Farmers Insurance Open
CFB

Quarterback Brayden Fowler-Nicolosi Signs with Michigan
Teuvo Teravainen

Set to Return Tuesday
CFB

Darian Mensah Reaches Settlement with Duke, Expected to Land at Miami
Simon Edvinsson

Out Until Olympics
Josh Norris

Won't Play This Week
Zeev Buium

Lands on Injured Reserve
Brock Boeser

Canucks Place Brock Boeser on Injured Reserve
Sean Durzi

Hurt on Monday Night
Lauri Markkanen

Expected to Return Tuesday
Keyonte George

Resting Tuesday
Malik Monk

Tagged as Questionable for Tuesday
Zach LaVine

Iffy for Tuesday's Action
Kawhi Leonard

Questionable Tuesday
Giannis Antetokounmpo

Without Timetable for Return
Devin Booker

Unavailable This Week
Anthony Edwards

Won't Play on Monday Night
Jusuf Nurkić

Jusuf Nurkic Not Expected to Play on Tuesday Night
Jalen Green

Questionable to Suit Up on Tuesday
Santi Aldama

Back in Action on Monday
Eugenio Suárez

Eugenio Suarez Not Drawing Interest on Open Market?
Tre Jones

Sidelined Versus Lakers
Jonas Brodin

to Miss 6-8 Weeks
Sam Merrill

Won't Play Monday
Kasperi Kapanen

Returns From Three-Game Absence Monday
Lawson Crouse

Available Against Lightning
Draymond Green

Considered Questionable for Monday
Carson Soucy

Won't Play Monday
Rasmus Ristolainen

Returns to Flyers Lineup
Ryan Pulock

Misses Second Consecutive Game
Shedeur Sanders

Named as Pro Bowl Replacement
Simon Holmstrom

a Game-Time Call Monday
Framber Valdez

Among Many High-End Pitchers on Free-Agent Market
Jose Altuve

Won't Participate in World Baseball Classic
Harrison Bader

Agrees With Giants on Two-Year Deal
Paddy Pimblett

Drops Decision
Justin Gaethje

Becomes the New Interim-Lightweight Champion
Song Yadong

Suffers Unanimous Decision Loss
MMA

Sean O'Malley Gets Back In The Win Column
Waldo Cortes-Acosta

Extends His Win Streak
Derrick Lewis

Suffers Second-Round TKO Loss
Los Angeles Chargers

Chargers Officially Hire Mike McDaniel as Offensive Coordinator
Nathan Eovaldi

Doesn't Expect Any Limitations in Spring Training
Jaxon Smith-Njigba

Dominates in NFC Championship Game Win
Scott Wedgewood

Activated From Non-Roster List
Nikita Zadorov

Questionable for Monday
Stephen Halliday

Injured Sunday
Jack St. Ivany

Exits With Upper-Body Injury Sunday
Brock Boeser

Takes Hit to the Head
Evgeni Malkin

Suffers Apparent Injury in Sunday's Win
Philipp Kurashev

Joins Sharks for Road Trip
Charle-Edouard D'Astous

Placed on Injured Reserve
Matthew Stafford

Plans to Return in 2026
CFB

Arthur Smith to Become Ohio State's Offensive Coordinator
Bo Nix

Sidelined for 12 Weeks With Broken Ankle
Jose Altuve

to Mainly Play Second Base
Yu Darvish

Considering Retirement
Pittsburgh Steelers

Steelers Finalizing Deal to Make Mike McCarthy Their Head Coach
José Ramírez

Jose Ramirez Signs Seven-Year Extension With Guardians
Gunnar Henderson

is Fully Healthy Heading into Spring Training
Tyreek Hill

Dolphins Expected to Release Tyreek Hill
Paddy Pimblett

Set For Interim Lightweight Title Fight
Justin Gaethje

An Underdog At UFC 324
Song Yadong

Looks To Win Back-To-Back Fights
MMA

Sean O'Malley Looks To Get Back In The Win Column
Derrick Lewis

Returns At UFC 324
Waldo Cortes-Acosta

Looks For His Third Consecutive Win
Philip Rivers

Interviewing for Bills Head-Coaching Job
NFL

Fernando Mendoza Officially Declares for NFL Draft
CFB

Arch Manning Undergoes Foot Surgery
Dalton Kincaid

Played Through Torn PCL
CFB

College Football Playoff Expected to Remain a 12-Team Field in 2026
Baltimore Ravens

Ravens Hire Jesse Minter as Their Head Coach
Indianapolis Colts

FBI Investigating the Death of Colts Owner Jim Irsay
MacKenzie Gore

Rangers Acquire MacKenzie Gore From the Nationals
Brandon Sproat

Dealt to Brewers in Four-Player Trade
Jett Williams

Brewers Acquire Jett Williams From Mets
Freddy Peralta

Mets Acquire Freddy Peralta From Brewers

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP