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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

NFL

First Round of NFL Draft Could Feature Plenty of Trades
Max Muncy

has Another Multi-Homer Game at Coors Field
Lourdes Gurriel Jr.

Expected to Make Season Debut on Saturday
Austin Riley

Hits Two Home Runs in Shutout Win Over Phillies
Daulton Varsho

Removed Early on Friday With Knee Discomfort
Rashawn Slater

Joe Alt Expected to Participate in Offseason Program
Aaron Gordon

Available for Game 1 Against Timberwolves
Julius Randle

Cleared for Playoffs
Jaxson Hayes

Available Saturday Night
Grayson Allen

Will Play Against Warriors
Kristaps Porzingis

Cleared for Friday's Game
Kevin Durant

Iffy for Saturday's Game 1
Mark Williams

Won't Play Friday Night
Spencer Jones

is Questionable for Game 1 on Saturday
Peyton Watson

is Ruled Out for Game 1 on Saturday
Edwin Uceta

Having More Shoulder Issues, "Shut Down for a Few Days"
Moussa Diabaté

Moussa Diabate is Available on Friday
Ayo Dosunmu

is Available for Saturday's Game
Anthony Edwards

Questionable for Saturday's Action
Jonathan Isaac

Remains Out Friday
NFL

Jeremiyah Love Considered the Top Overall Talent in 2026 NFL Draft?
Jarrett Allen

Removed From Injury Report Ahead of Playoffs
Donovan Mitchell

Good to Go for Playoff Opener
Mitchell Robinson

Ready for Game 1 Against Hawks
OG Anunoby

Cleared to Play Saturday
Jalen Brunson

Available for Game 1 Saturday
Thomas Bryant

Won't Play Saturday
Immanuel Quickley

Questionable for Game 1
Kristaps Porzingis

Expected to Play Friday
Aaron Jones Sr.

Role in Minnesota Could Continue to Decrease in 2026
Romeo Doubs

Appears Poised for Larger Role in New England
Isiah Pacheco

Is Isiah Pacheco a Worthy Buy-Low Target for Dynasty Managers?
Rico Dowdle

Will Rico Dowdle Emerge as the Clear RB1 in Pittsburgh?
Rashid Shaheed

Can Rashid Shaheed Establish a Higher-Volume Role in Seattle in 2026?
Marcus Mariota

Set for Backup Role in 2026
Josh Hader

Moved to 60-Day Injured List
Ruke Orhorhoro

Jaguars Acquire Ruke Orhorhoro From the Falcons
NFL

Jordyn Tyson Could Come Off the Board as Early as Fifth Overall
Willson Contreras

Returns to Red Sox Lineup on Friday
Daniel Palencia

Goes on 15-Day Injured List With Oblique Strain
Jacoby Brissett

Sitting Out Offseason Workouts, Asking for Extension
Will Anderson Jr.

Texans Agree to Three-Year Extension With Will Anderson Jr.
Juan Soto

Still on Track to Return Next Week
Los Angeles Angels

Garret Anderson Dies at 53 Years Old
Pittsburgh Steelers

Steelers Not Expected to Take a QB at No. 21 Overall in the Draft
NFL

Jordyn Tyson's Friday Workout to be Heavily Attended
Quentin Johnston

Chargers Shut Down Trade Rumors Surrounding Quentin Johnston
Najee Harris

a Name to Remember After the NFL Draft
Mike Malott

A Favorite At UFC Winnipeg
NFL

Malachi Fields Could Provide More Value to NFL Team Than Fantasy Managers
Gilbert Burns

Set For UFC Winnipeg Main Event
Travis Etienne Jr.

Entering a Second Dynasty Peak
Kyler Phillips

Set UFC Winnipeg Co-Main Event
Charles Jourdain

Looks To Extend His Win Streak
Tyler Allgeier

Familiarity with System Could Give Him an Early Edge
Jai Herbert

An Underdog At UFC Winnipeg
Kenneth Gainwell

Should Carve Out Meaningful Role with Buccaneers
Mandel Nallo

Set For His UFC Debut
Karine Silva

Looks To Get Back In The Win Column
Jasmine Jasudavicius

Looks To Bounce Back
Robert Thomas

Wraps Up Season With a Hat Trick
Macklin Celebrini

Establishes Sharks' New Scoring Record
Scott Wedgewood

Keeps Kraken From Scoring Thursday
Nathan MacKinnon

Wins Rocket Richard Trophy With 53 Goals
Connor McDavid

Secures Sixth Art Ross Trophy With Four-Assist Performance
Connor Dewar

Ready for Game 1
Nikita Grebenkin

Unavailable at Start of Playoffs
Parker Messick

Flirts With No-Hitter in Latest Gem Against Orioles
Mike Trout

Hits Five Homers in Series Versus Yankees
CGY

Arsenii Sergeev to Make NHL Debut Thursday
Aleksander Barkov

Cleared for World Championship
Pierre-Luc Dubois

Dealing With Fractured Hand
Zach Whitecloud

Ready to Rock Thursday
Matt Coronato

Available Against Kings
Josh Manson

Expected to Return for Postseason
Nathan MacKinnon

Martin Necas Sit Out Regular-Season Finale
Spencer Arrighetti

Fans 10 in Season Debut, to Remain a Focal Point in Rotation?
Nick Pivetta

Dealing With Flexor Strain, Could Miss Months
Nico Hoerner

Homers, Drive in Five in Win Over Phillies
Shota Imanaga

Strikes Out 11 in First Win of the Season
Sal Stewart

Continues to Hit, Goes Deep Twice on Wednesday
Shohei Ohtani

Strikes Out 10 in Win Over Mets
Connor Bedard

Has Two Assists in Season Finale
Claude Giroux

Sends Out Two Assists in Battle of Ontario Win
Tye Kartye

Registers First Career Three-Point Game
Owen Power

Records Two Assists Wednesday
Esa Lindell

Tallies Two Points in Regular-Season Finale
Reilly Smith

Produces Three-Point Performance Wednesday
Shane Wright

Returns With a Goal Wednesday
Shohei Ohtani

Will Pitch on Wednesday, But Won't DH
Nick Pivetta

Confident he'll Pitch Again This Year
Trevor Story

Carries Red Sox With Five RBI on Wednesday
CFB

Michigan Lands Commitment From Quarterback Kamden Lopati
Sahith Theegala

Brings Strong Form Into Harbour Town
Wyndham Clark

Needs Putter to Show Up at RBC Heritage
Jacob Bridgeman

Looks to Return to Elite Form at Harbour Town
J.J. Spaun

a Volatile Option at RBC Heritage
PGA

Sungjae Im Offers High-Upside Value at RBC Heritage
Matt Fitzpatrick

Set for Another Strong Showing at RBC Heritage
Jason Day

Eyes Bounce-Back After Sunday Struggles at the Masters
Akshay Bhatia

Looking to Rebound at Harbour Town
Cameron Young

Hoping to Secure Second Win of Season at RBC Heritage
Scottie Scheffler

Looks to Win Again at RBC Heritage
Shane Lowry

Has Disappointing Final Round at Masters
Viktor Hovland

Hoping to Build on Final Round at Masters
Brian Harman

Struggling For Consistency Heading to RBC Heritage
Chris Gotterup

Putting Together Outstanding 2026 Season
Justin Thomas

Looks to Defend in Hilton Head
Jordan Spieth

in Search of Improved Putting at RBC Heritage
Marco Penge

May Continue Up-and-Down Ride at the RBC Heritage
Xander Schauffele

Could Get The Job Done at RBC Heritage
Jake Knapp

Keeps Building Strong Results in 2026
Kurt Kitayama

Trying to Regain Form From Florida
Collin Morikawa

Continues to be a Scary DFS Play at RBC Heritage
CFB

Tramell Jones Jr. Outperforms Aaron Philo During Florida's Spring Scrimmage
CFB

Keelon Russell Flashes in Alabama's Spring Game
Ty Gibbs

Holds off the Field for His First Cup Series Victory at Bristol
Ryan Blaney

Earns His First Runner-Up Finish at Bristol
Kyle Larson

Dominant Performance At Bristol Falls Short of Victory
Tyler Reddick

Matches his Career-Best Finish at Bristol
Alex Bowman

Crashes Early at Bristol in Return From Injury
Carlos Ulberg

Is The New Light Heavyweight Champion
Jiří Procházka

Jiri Prochazka Suffers First-Round Knockout Loss
Azamat Murzakanov

Suffers His First Loss
Paulo Costa

Wins Back-to-Back Fights
Curtis Blaydes

Drops Decision At UFC 327
Josh Hokit

Remains Unbeaten
Carson Hocevar

Is Carson Hocevar A Worthy DFS Option for Bristol Lineups?
NASCAR

Could Bubba Wallace Be A Solid DFS Option for Bristol Lineups?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF