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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Akshay Bhatia

Riding Strong Form Into the Valspar Championship
Darnell Mooney

Poised for Large Role in Giants Offense?
Nathan Carter

the New Handcuff at RB in Atlanta?
Jalen Tolbert

the New WR2 in Miami?
Pascal Siakam

Likely to Remain Out Tuesday
Patrick Cantlay

Playing Well Heading to Valspar Championship
Keegan Bradley

Needs Improvement From Approach Play at Valspar Championship
Kevin Porter Jr.

Available Against Cavaliers
Jalen Brunson

Questionable for Tuesday's Game
Dylan Sampson

Set to be Pass-Catching Backup RB in Cleveland
Joel Embiid

to Remain Out Tuesday
Jaylin Noel

Dynasty Value on the Rise, Could be WR3 in 2026
Jarrett Allen

to Sit Out At Least Three More Games
Keenan Allen

Fantasy Stock Continues to Fall as he Nears the End of his Career
Trae Young

Exits Early Monday Due to Quadriceps Contusion
Drake London

to be a Volatile WR2 With QB Uncertainty?
John Collins

Starting Against Spurs
Craig Porter Jr.

Out 1-3 Weeks With Groin Strain
Russell Westbrook

Off Injury Report for Tuesday
Clint Capela

Alperen Sengun Sidelined, Clint Capela Starting Against Lakers
Bam Adebayo

Iffy for Tuesday Night
Walter Clayton Jr.

Javon Small Out Monday, Walter Clayton Jr. Returns to Starting Lineup
Giannis Antetokounmpo

Listed as Questionable for Tuesday
Rayan Rupert

GG Jackson II Out, Rayan Rupert to Start Against Bulls
Anthony Edwards

Ruled Out for Tuesday
Nick Richards

Cleared to Play Monday
Dejounte Murray

Sidelined by Illness Monday
Ty Jerome

Ruled Out Monday
Daniel Gafford

Won't Play Against Pelicans
George Holani

Signs Tender Offer on Monday
Vít Krejčí

Vit Krejci Unavailable Monday
Robert Williams III

Won't Play Monday
Johan Rojas

Suspended 80 Games for PED Violation
José Ramírez

No Plans for Jose Ramirez to Undergo Imaging on Injured Shoulder
Darius Slay

Retires From the NFL
Seiya Suzuki

Undergoing MRI Exam on Monday
Joe Musgrove

Expected to Open the Year on the Injured List
Christian Kirk

49ers Sign Christian Kirk to One-Year Deal
Matt McCarty

Could Thrive at the Valspar Championship
Michael Kim

Seeks to Dust Off Tough Week at TPC Sawgrass
Max Homa

Enjoying a Solid 2026 Heading into Valspar Championship
Nick Dunlap

Keeps Slugging Through Rough 2026 Season
Zach Neto

Expected to Return to Game Action on Tuesday
Kyren Williams

Will Kyren Williams Remain the Undisputed RB1 in Los Angeles Going Forward?
Mason Taylor

Does Mason Taylor Have Breakout Potential in 2026?
Puka Nacua

Appears Poised to Dominate for Years to Come
Andrew Novak

Wants to Rebound After The Players Championship
Austin Smotherman

on Baby Watch as Valspar Championship Approaches
Ben Sinnott

Does Not Appear to Be in Washington's Long-Term Plans
Luke Clanton

Might Have Issues at the Valspar Championship
Sam Darnold

Profiles as a Safe QB2 in Dynasty Formats Heading into 2026
Jerry Jeudy

Can Jerry Jeudy Bounce Back from Underwhelming 2025 Campaign?
Christiaan Bezuidenhout

Must be Accurate at the Valspar Championship
Josh Emmett

Suffers First-Round TKO Loss
Kevin Vallejos

Scores First-Round TKO
Amanda Lemos

Drops Back-To-Back Fights
Gillian Robertson

Extends Her Win Streak
Zach Neto

to Take Batting Practice on Monday
Andre Fili

Drops Decision on Saturday
Cam Skattebo

Thinks he'll be 100 Percent Healthy in a Little Over a Month
Denny Hamlin

Dominates and Gets His Third Career Las Vegas Win
Chase Elliott

Earns Runner-Up Finish at Las Vegas
William Byron

Wins A Stage and Finishes Third at Las Vegas
Jeremy McNichols

Re-Signs With Commanders
Christopher Bell

Finishes Fourth at Las Vegas After Strong Run
Kyle Larson

Fades to Seventh Despite Leading Laps Early at Las Vegas
Justin Fields

Chiefs Acquiring Justin Fields From Jets
Andre Fili

Jose Delgado Edges Andre Fili in Split-Decision Win
Oumar Sy

Suffers First-Round Submission Loss
Ion Cutelaba

Returns To The Win Column
CFB

CJ Carr Enters Sophomore Season as Heisman Favorite
CFB

Aaron Philo Not a Lock to be Florida's Starting QB?
CFB

George MacIntyre the Favorite to Win Tennessee Quarterback Battle?
CFB

Keelon Russell, Austin Mack Battling for Alabama QB1 Duties
Connor McDavid

Records Three Assists Sunday
Bo Groulx

Makes Big Impact Sunday
Drake Batherson

Pots Two Goals in Sunday's Win
Bobby McMann

Continues Dream Start in Seattle
Kirby Dach

Injured on High Hit
Alexander Wennberg

Without Timeline for Return
Leon Draisaitl

Exits Early with Injury Sunday
Harold Fannin Jr.

Officially Steps Into the Top Role
Troy Franklin

Ready to Take on an Even Larger Role?
Troy Terry

Adds Three Points in Return to Lineup
Leo Carlsson

Picks Up Trio of Points on Sunday
José Ramírez

Jose Ramirez is Day-to-Day with Shoulder Inflammation
Brendan Gallagher

Rejoins Canadiens Lineup Sunday
Daniil Tarasov

Starting Against Kraken
Ty Emberson

Remains Out Sunday
Bobby Brink

Questionable Sunday
Oliver Ekman-Larsson

Unavailable Against Wild
Ryan Nugent-Hopkins

a Game-Time Call Sunday
Corbin Carroll

to Resume Playing Defense This Week
John Carlson

Set for Ducks Debut
Francisco Lindor

Non-Committal About Status for Opening Day
Nathan Eovaldi

Named Rangers' Opening Day Starter
Hayden Birdsong

Diagnosed with Grade 2 Forearm Strain and UCL Sprain
Marcelo Mayer

Scratched With Left-Knee Soreness
Zach Neto

Tests Come Back Negative, Dealing With Sprained Hand
Christopher Bell

Looking for Redemption, Wins Pole at Las Vegas
Denny Hamlin

Should Contend for Another Vegas Win
Chase Briscoe

Qualifies 18th Despite Toyota Dominating at Las Vegas
Chase Elliott

May Fly Under the Radar at Las Vegas
NASCAR

Ross Chastian Has Been As Solid As They Come at Las Vegas
Ty Gibbs

Could Ty Gibbs Finally Break Through With a Win at Las Vegas?
Brad Keselowski

a Solid DFS Pick at Las Vegas
Francisco Lindor

is Making Spring Debut on Sunday
Carter Verhaeghe

Anton Lundell Expected to Return Sunday
Kyle Larson

Should Kyle Larson be Considered A Favorite for Las Vegas?
Sam Bennett

Considered Day-to-Day
William Byron

Could Compete for a Top-Five Finish at Las Vegas
Sam Reinhart

Not Traveling on Four-Game Road Trip
Ryan Blaney

Is Ryan Blaney Worth Rostering in Tournament DFS Lineups for Las Vegas?
Michael Rasmussen

Ruled Out for One Week
Tyler Reddick

Could Continue his Top-10 Streak at Las Vegas
Declan Carlile

to Miss 4-5 Weeks
Joey Logano

Should DFS Managers Underestimate Joey Logano for Las Vegas?
Chris Buescher

Is Chris Buescher Worth Rostering For Las Vegas DFS Lineups?
NASCAR

Bubba Wallace is A Risky DFS Option Who Could Pay Off at Las Vegas
Josh Berry

Has Plenty of Upside for Las Vegas DFS Lineups
Ryan Preece

Scores his First Las Vegas Top-10 Starting Spot in Qualifying
Seiya Suzuki

Leaves WBC Game on Saturday With Right-Knee Discomfort
Zach Neto

is Removed After Suffering Hand Injury
Joe Ryan

Won't Pitch in the World Baseball Classic
Zack Wheeler

Throws First Live BP Session on Saturday
Merrill Kelly

Expected to Open Season on the Injured List
Kevin Gausman

Named Toronto's Opening Day Starter
Kyle Stowers

Back in Grapefruit League Lineup
Kevin Vallejos

Looks To Remain Undefeated In The UFC
Josh Emmett

In Dire Need Of Victory
Gillian Robertson

A Favorite At UFC Vegas 114
Amanda Lemos

Set For Co-Main Event
Oumar Sy

Looks To Win Back-To-Back Fights
Ion Cutelaba

Looks To Get Back In The Win Column
Hideki Matsuyama

Brings Strong Course History to TPC Sawgrass
Adam Scott

in Strong Form Ahead of The Players
Rickie Fowler

on Quite the Run Heading to TPC Sawgrass
Sepp Straka

Needs to Forget What Happened Sunday at Bay Hill
Jordan Spieth

an Enigma Heading to The Players Championship
Justin Rose

Trying to Pick Up the Pieces in Florida
Maverick McNealy

Bounces Back at Arnold Palmer Invitational
Brooks Koepka

Continues His Florida Swing With Some Momentum
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF