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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Jaden Ivey

Shut Down for at Least Two Weeks
Joe Ryan

Scratched From Grapefruit League Start With Back Tightness
Merrill Kelly

Scratched From Live BP With Back Tightness
Jack Suwinski

Dodgers Claim Jack Suwinski Off Waivers From Pirates
Andrew Vaughn

Can Andrew Vaughn Repeat 2025 Breakout Success?
Brenton Doyle

Carries Buy-Low Potential Heading into 2026
Jack Flaherty

Can Jack Flaherty Bounce Back After 2025 Struggles?
Colton Cowser

Looking to Rebound from Injury-Marred 2025 Campaign
Yandy Díaz

Can Yandy Diaz Repeat 2025 Power Surge?
Sal Stewart

Playing Second Base in First Spring Training Outing
Zach Collins

to Miss Rest of 2025-26 Season
De'Andre Hunter

to Undergo Season-Ending Eye Surgery
Tristan Vukcevic

Exits Early Vs. Pacers
John Collins

Leaves Game with Head Injury
Kawhi Leonard

Exits Early Friday Night
Devin Booker

Sidelined vs. Orlando
Joel Embiid

Out Saturday vs. Pelicans
Kevin McGonigle

Starting at Shortstop in Grapefruit League Opener
Bo Bichette

Batting Third in Mets Spring Training Debut
J.J. Wetherholt

JJ Wetherholt Playing Second, Batting Fifth in Grapefruit League Opener
Kazuma Okamoto

Hitting Third in Grapefruit League Opener
Jorge Polanco

Expected to See a Lot of Time as Designated Hitter
Blake Coleman

Activated From Injured Reserve
Ramón Urías

Ramon Urias Agrees on One-Year Deal With Cardinals
Matt Rempe

Heading to Injured Reserve After Second Thumb Procedure
Roman Anthony

Expected to Hit Leadoff for Boston
Sidney Crosby

a Game-Time Call for Olympic Final
Edwin Uceta

has Shoulder Inflammation, Slight Impingement
Josh Morrissey

Won't Play Sunday
Filip Chytil

Out Indefinitely With Facial Fracture
Connor McDavid

Makes History With Another Multi-Point Outing
Tage Thompson

Expected to Play in Olympic Final
Shohei Ohtani

Might Not be Fully Built Up as a Pitcher by Opening Day
Travis Etienne Jr.

has "Legitimate Interest" in Joining Chiefs
Zach Charbonnet

Undergoes Knee Surgery on Friday
Austin Reaves

Back in Starting Five
Matisse Thybulle

Kris Murray, Matisse Thybulle Suit Up Friday
Scoot Henderson

No Longer Limited
Ben Joyce

Throws Successful Bullpen Session on Friday
Jamal Murray

Jalen Pickett Available Friday vs. Portland
Yoshinobu Yamamoto

to Start on Saturday
LeBron James

Upgraded to Available Friday vs. Clippers
Bryan Ramos

Orioles Claim Bryan Ramos Off Waivers From Cardinals
Max Christie

is Downgraded to Out
Evan Mobley

is Unavailable for Friday's Game
Tyler Herro

to Make his Return on Friday
Norman Powell

is Cleared to Play on Friday
Nicolas Claxton

to Remain Out on Friday
Kyshawn George

Won't Play on Friday
Andrew Nembhard

is Ruled Out on Friday
T.J. McConnell

is Available on Friday
CFB

Curt Cignetti Agrees to New Deal With Indiana, Will Earn $13.2 Million Per Year
Ukko-Pekka Luukkonen

Returns to Practice
Josh Morrissey

Remains Out Against Finland
Sidney Crosby

Won't Play Friday
Anthony Hernandez

Set For UFC Houston Main Event
Sean Strickland

Looks To Get Back In The Win Column
Uros Medic

Set For UFC Houston Co-Main Event
Geoff Neal

Looks To Get Back In The Win Column
Melquizael Costa

A Favorite At UFC Houston
Dan Ige

An Underdog At UFC Houston
Logan Cooley

Sheds Non-Contact Jersey
Maxwell Crozier

to Miss 10 Weeks After Surgery
Kirill Marchenko

Dealing With Lower-Body Injury
Petr Mrazek

Undergoes Season-Ending Surgery
Victor Hedman

Suffers Lower-Body Injury
Sidney Crosby

Considered Day-to-Day
Rashee Rice

Accused of Assault by Long-Time Girlfriend
Ben Griffin

Looking to Return to Top Form at Riviera
Keegan Bradley

Looking to Build Momentum at Riviera
J.J. Spaun

Putting a Major Concern at Riviera
Sepp Straka

May Have Tough Time at The Genesis Invitational
Shane Lowry

Trending Up Entering the Genesis Invitational
Justin Rose

Off Most Radars at The Genesis Invitational
Robert MacIntyre

a Long Hitter to Watch at Riviera Country Club
Jake Knapp

Red-Hot Heading to Riviera
Min Woo Lee

Attempts to Build Momentum After Pebble Beach
Harry Hall

an Unknown for The Genesis Invitational
Matt Fitzpatrick

Has Favorable Path to Success at Riviera This Week
Wyndham Clark

Not Likely to Contend at Genesis Invitational
Ludvig Aberg

Might Find the Genesis Invitational More Challenging
Harris English

Carries Strong Form to Riviera
Patrick Cantlay

Eyes Another Strong Week at The Genesis Invitational
Daniel Berger

Needs Short Game to Show Up at Riviera
Sam Burns

Hopes Return to Form Continues at Riviera
Collin Morikawa

Riding Wave of Victory Into Riviera
Hideki Matsuyama

Looks to Have Repeat Success at The Genesis Invitational
Scottie Scheffler

Looks to Find Paydirt at Riviera
Xander Schauffele

Rounding into Form Before Genesis Invitational
Morgan Rielly

Available After Olympic Break
Charlie Lindgren

Practices Fully Tuesday
John Carlson

Ready to Rock After Olympics
Radek Faksa

Unavailable Against Team Canada
Anton Lundell

Good to Go Wednesday
Mike Evans

Will Return in 2026
Kenneth Walker III

Seahawks Not Expected to Use Franchise Tag on Kenneth Walker III
Bucky Irving

Undergoes Offseason Shoulder Surgery
Tyreek Hill

Says he Will Play in 2026
Joey Logano

Finishes Third in the 2026 Daytona 500
Ricky Stenhouse Jr

. Finishes as the Runner-Up in the Daytona 500
Chase Elliott

Falls Short of His First Daytona 500 Victory Again
Brad Keselowski

Ends Daytona 500 With a Top-Five Finish
Tyler Reddick

Wins the Daytona 500 for the First Time with 23XI Racing
Tyreek Hill

Released by Dolphins
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF