👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Titans vs 49ers Start 'Em, Sit 'Em: A.J. Brown, Brandon Aiyuk, Jeff Wilson, D'Onta Foreman

Deebo Samuel - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Fantasy football start em, sit em and lineups advice for the Titans vs 49ers Thursday game in Week 16 (2021). Ellis Johnson analyzes the TNF matchups with a detailed breakdown.

We are officially in the fantasy playoffs for all leagues. For those of you who made it, congratulations. To those of you joining us after a bye week, I hope you didn’t get too comfortable. Lastly, to those of us that missed playoffs, let’s focus on the holiday season and enjoy the NFL playoff push.

Last week was wildly mediocre for fantasy. In what was most fantasy manager’s worst nightmare, we had one of the lowest scoring Week 15’s of all time. This included star fantasy players such as Ja'Marr Chase, Alvin Kamara, Najee Harris, and many others, posting season-low fantasy weeks. On top of this, we had a few monster games from the usual suspects (Travis Kelce and Mark Andrews for example) as well as Tyler Huntley and Duke Johnson Jr. 

Going into Week 16, we can only hope for a better fantasy output. To start the week off we have two teams that are both on the verge of making the postseason. The revitalized 49ers are traveling to Nashville to take on a hobbled Titans team. As always, my name is Ellis Johnson, and this is your RotoBaller Thursday Night Preview.

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

San Fransisco 49ers @ Tennessee Titans - 8:20 pm ET 

Notable Injuries

 

Must-Starts for Fantasy Football Lineups

A.J. Brown (WR, TEN): He’s back baby. Well, hopefully he is back. After being activated from the Injured Reserve earlier this week, all signs are pointing in the right direction. The young superstar has been very disappointing for fantasy this season. Not only has he missed a significant portion of the season due to injuries, but he also had five of his nine games under 10 fantasy points. Thankfully we have seen stretches this season that showcase the upside of Brown, with two consecutive weeks with 130+ receiving yards and a score. The Titans are taking on a 49ers team that ranks 11th in fantasy points allowed to the position. The Titans offense has been struggling, and Brown just might be the spark they need to get back on track. I would start AJB as a solid WR1 this week.

UPDATE: A.J. Brown has officially been activated from IR and will return this week.

Deebo Samuel (WR, SF): Speaking of WR1’s, holy smokes is Deebo Samuel having a year. Whether he is a receiver or running back, Samuel has become the best in the league at yards after the catch. He is currently the WR2 on the season and has the second most touchdowns at the position. In both of the categories, he is only trailing Cooper Kupp and of his 12 touchdowns, seven are rushing touchdowns. With the 49ers backfield being a revolving door, Samuel has become not only their leading receiver but the team's lead back when necessary. Samuel is one of the most versatile players in the league and should continue to carry your fantasy team this week against the team that allows the second-most fantasy points to the WR position. 

George Kittle (TE, SF): Here we transition from one yards after the catch monster to another. Ironically on the same team, Kittle has put his athletic abilities on full display these last few weeks. Since returning from injury, Kittle has been on a tear. Over this seven-week period, he only has one week below ten fantasy points, averaging 89 receiving yards and 0.86 touchdowns. Oh, and also he is the TE-one over the last seven weeks. Unless you are against Andrews or Kelce, Kittle is a massive fantasy advantage at the position. I would look for him to continue his dominance in this good matchup. 

 

Solid Options for Fantasy Football Lineups

D'Onta Foreman (RB, TEN): From the depths of the fantasy underworld, Foreman has resurfaced himself and taken over one of the league’s most prolific rushing offenses. For those of you who believe his resurgence has come out of nowhere, here is a little history. The 2016 Doak Walker Award Winner (given to the best college running back) entered the league with a lot of buzz. After being drafted to the Texans in 2017 in the third round, he found himself sitting behind the veteran Lamar Miller. In his limited work, he displayed explosiveness and promise. Unfortunately with an Achilles tear in 2018, he found himself being picked up by the Colts off of waivers in 2019. He then had to leave after tearing his bicep in the preseason and tried out for the Titans in 2020. Flash forward to now, and we have ourselves the RB10 over the last two weeks. All of that was to say that this kid had promise and has had to overcome devastating injuries. Over his last three games, he has 100 yards rushing twice and found the endzone in the third game. If you managed to pick him up from your waivers you are most likely playing him out of necessity, however, he is a solid play against a mild-tier 49er run defense. 

Jimmy Garoppolo (QB, SF): Since Week 12, Jimmy G has quietly snuck his way into the QB-one category. Over these last three games, he is the QB11 and is the QB18 on the season. In the last four games, he has torched teams for 230+ yards in each game, including two games narrowly missing the 300-yard mark. When you have weapons like Samuel and Kittle, managers have been relieved to see the veteran QB start airing out the ball. Tennessee's defense is in the top half in most points allowed to the QB position this season. If you are desperate for a playoff QB or need a solid QB-two this week, Jimmy Garoppolo is a solid play this Thursday.

 

Flex Considerations for Fantasy Football Lineups

Ryan Tannehill (QB, TEN): Unfortunately, Tannehill just hasn’t been cutting it for fantasy teams. It’s hard to blame the veteran after losing key players in Derrick Henry, A.J. Brown, and Julio Jones for most of the year. It came as no surprise that losing Henry slowed the entire fantasy offense, but ironically, the loss of the star running back has impacted Tannehill the most. Failing to score 10 fantasy points in three of his last four games, it’s hard to trust Tannehill this week. Thankfully, he possesses upside with his legs, as he has scored twice on the ground over the last two weeks. Plus, the return of A.J. Brown does spark some optimism. However, he is no more than a high-upside/low-floor play this week against a very solid 49ers defense.

Brandon Aiyuk (WR, SF): If there was an award for the scariest player to start in fantasy, Aiyuk would have to be in the running. After being praised all offseason, he literally disappeared at the start of the season. Then, seemingly out of the blue, he started seeing starter snap counts and six or more targets in six of the last eight games. Then, once you finally feel comfortable playing him, he catches one of two targets for 36 yards against a poor Falcons secondary last week. Thankfully he gets the chance to redeem himself against another exploitable opponent. The Titans are allowing the second-most fantasy points to the position and could provide some life for the young receiver. However, because we saw a good matchup last week and it did not translate for Aiyuk’s fantasy success, he is hard to trust as more than a high-upside flex play this week.

 

Consider Sitting for Fantasy Football Lineups

Jeff Wilson Jr. (RB, SF): Yes, Elijah Mitchell has been ruled out. Yes, Wilson Jr. is coming off a monster game. No, I don’t think you should play him if you have other alternative options. Well, at least I think you should be careful if you do decide to start him. This “sit” is a result of Tennessee being the best fantasy defense against running backs on the season. They have managed to shut down the run all season, and that continued last week as they stiffed Najee Harris. Wilson Jr. finally had the game managers had been waiting for, however, I don’t want to rely on one good performance in the fantasy playoffs, especially against a very tough opponent. I would look elsewhere this week if possible.

Other Titans pass-catchers: Whether you are holding onto Julio Jones or are taking a shot at Anthony Firkser, Nick Westbrook-Ikhine, or Chester Rogers, I don’t think you can play any of them this week. Not only have the 49ers been very solid on defense these last few weeks, but these players also have not been reliable for fantasy. Although it is tough to sit Julio Jones if he is active, I would not want to risk the possibility of reinjury this week. My favorite player of this group has to be Westbrook-Ikhine as he has seen six or more targets in three of the last four games, but I would try to find the higher upside in another flyer this week.

 

As soon as we were heating up, we cooled right down. Thanks to a massive fourth quarter and an overtime touchdown, we missed on both of our picks last week. Nevertheless, we go into this week with fresh eyes. The Titans have been playing miserable football recently, while the 49ers could be argued to be one of the hottest teams in the league right now. Additionally, with the Titan's lack of passing defense and desperation to turn their season around at home, this could be a fun game to start Week 16. I wish you all the best of luck this week and happy holidays! 

Ellis’ Picks: 49ers -3.0 (12-5), Over 44.0 (11-6)

Career record: Spread (21-14), Over/Under (20-15)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Chase Brown

an Important Name to Monitor on Night One of the NFL Draft
Bijan Robinson

Could Just Be Entering His Prime
Jameson Williams

Consistency the Key to a True Jameson Williams Breakout
Jarace Walker

May Exit Pacers Lineup Again Thursday
Aaron Nesmith

Out for Sixth Consecutive Game
T.J. McConnell

Andrew Nembhard, T.J. McConnell Unavailable Thursday
Dru Smith

Iffy for Thursday
Norman Powell

Questionable Thursday
Sam Hauser

Could Miss Thursday's Game
Neemias Queta

Uncertain for Thursday
Zach Benson

Scores Twice in Comeback Victory
Logan Thompson

Shuts Out the Leafs
Zach Eflin

Undergoes Successful Elbow Surgery, Will Miss Remainder of 2026
Derrick White

Listed as Questionable for Thursday
Tre Johnson

Iffy for Thursday
Jaylen Brown

Iffy to Face Knicks
Bilal Coulibaly

Questionable Against Bulls
Gui Santos

Could Miss Another Game Thursday
Alexandre Sarr

Out Again Thursday
Al Horford

to Remain Out Thursday
Caleb Martin

Remains Sidelined Wednesday
Kristaps Porzingis

Unavailable Against Lakers
Klay Thompson

Ruled Out Wednesday
Stephen Curry

Questionable for Thursday Night
Brandon Williams

to Miss Back-To-Back with Illness
LeBron James

Ready to Return Thursday
Daniel Gafford

Ruled Out Vs. Phoenix
J.K. Dobbins

Broncos Prioritized Re-Signing J.K. Dobbins
NFL

Francis Mauigoa to Undergo Additional Imaging on a Back Issue
Kaleb McGary

Retires After Seven Years in the NFL
Jawaan Taylor

Signs with the Falcons
Andrei Kuzmenko

to Be Re-Evaluated in 7-8 Days
Mason Appleton

Won't Play Thursday
Tony DeAngelo

Expected to Return Thursday
John Klingberg

Rejoins Sharks Lineup Wednesday
Alex Lyon

Dealing With Lower-Body Injury
Oliver Ekman-Larsson

Back in Action Wednesday
Alex Ovechkin

Won't Decide Future Until Offseason
Cole Ragans

"Should be Good" for Next Start
Reynaldo López

Reynaldo Lopez Handed Seven-Game Suspension
Jorge Soler

Suspended Seven Games, Will Appeal
NFL

NFL Scouts See Plenty of Upside With Drew Allar
NFL

Ty Simpson to Fall into Second Round in NFL Draft?
Cleveland Browns

Todd Monken "Fired Up" About Quarterback Competition
Cleveland Browns

KC Concepcion Visiting With the Browns
Cole Ragans

Diagnosed With Thumb Contusion
Houston Texans

Texans Pick Up Will Anderson's Fifth-Year Option
C.J. Stroud

Texans Exercise C.J. Stroud's Fifth-Year Option
Cole Ragans

Leaves Early on Wednesday After Being Hit in the Hand
Jacob deGrom

Expects to Make his Next Start
Konnor Griffin

Pirates Sign Konnor Griffin to Nine-Year Extension
Parker Washington

Undervalued Despite League-Winning Finish in 2025
Nico Collins

Is Nico Collins Still a Dynasty WR1?
Rome Odunze

Does Rome Odunze Offer the Highest Ceiling in Chicago?
Justus Annunen

Ends Predators' 120-Game Streak Without a Shutout
Tank Bigsby

Still Holds Value Despite Limited Usage
Trevor Zegras

Leads Flyers to Victory Tuesday
Matthew Golden

A Matthew Golden Breakout Still Faces Obstacles
Kevin Bahl

Sustains Lower-Body Injury Against Stars
Michael Rasmussen

Likely to Miss Rest of Regular Season
Dmitry Kulikov

Done for the Season After Breaking Finger
Jalen Chatfield

Exits Early With Lower-Body Injury
Nazem Kadri

Suffers Upper-Body Injury Tuesday
Ray Davis

Patience Dwindling for Ray Davis' Dynasty Managers?
Ja'Marr Chase

a Real Threat to Finish as Overall WR1?
Javonte Williams

Returning to Face Minimal Competition?
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Morgan Geekie

Collects Second Career Hat Trick
Joel Eriksson Ek

has Three Points in Victory
Jacob deGrom

Doesn't Have Structural Damage in his Knee
J.T. Realmuto

Leaves Game on Tuesday Due to Bruised Right Foot
Cody Ponce

to Have Knee Surgery, Expected to Miss Six Months
Alejandro Kirk

Facing Six-Week Absence
Jacob deGrom

to Undergo MRI on Tuesday
Mike Trout

Back in the Lineup on Tuesday
Hunter Brown

Diagnosed with Grade 2 Shoulder Strain
Pavel Mintyukov

Returns From Three-Game Absence
Cutter Gauthier

Remains Sidelined Tuesday
Kirby Dach

Ready to Return Tuesday
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Cade Horton

to Undergo Season-Ending Elbow Surgery
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Jacob deGrom

Pitches Through Knee Issue on Monday
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Mike Trout

Held Out of Series Opener Against Braves
Alejandro Kirk

to Undergo Thumb Surgery on Tuesday
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
Chris Duncan

Set For UFC Vegas 115 Main Event
Renato Moicano

An Underdog At UFC Vegas 115
Tabatha Ricci

Set For UFC Vegas 115 Co-Main Event
Virna Jandiroba

Looks To Bounce Back
Brendson Ribeiro

In Desperate Need Of Win
Abdul-Rakhman Yakhyaev

Looks To Remain Unbeaten
Ethyn Ewing

Set For His Second UFC Bout
Rafael Estevam

Looks To Remain Undefeated
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF