👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

Titans vs 49ers Start 'Em, Sit 'Em: A.J. Brown, Brandon Aiyuk, Jeff Wilson, D'Onta Foreman

Deebo Samuel - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Fantasy football start em, sit em and lineups advice for the Titans vs 49ers Thursday game in Week 16 (2021). Ellis Johnson analyzes the TNF matchups with a detailed breakdown.

We are officially in the fantasy playoffs for all leagues. For those of you who made it, congratulations. To those of you joining us after a bye week, I hope you didn’t get too comfortable. Lastly, to those of us that missed playoffs, let’s focus on the holiday season and enjoy the NFL playoff push.

Last week was wildly mediocre for fantasy. In what was most fantasy manager’s worst nightmare, we had one of the lowest scoring Week 15’s of all time. This included star fantasy players such as Ja'Marr Chase, Alvin Kamara, Najee Harris, and many others, posting season-low fantasy weeks. On top of this, we had a few monster games from the usual suspects (Travis Kelce and Mark Andrews for example) as well as Tyler Huntley and Duke Johnson Jr. 

Going into Week 16, we can only hope for a better fantasy output. To start the week off we have two teams that are both on the verge of making the postseason. The revitalized 49ers are traveling to Nashville to take on a hobbled Titans team. As always, my name is Ellis Johnson, and this is your RotoBaller Thursday Night Preview.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

San Fransisco 49ers @ Tennessee Titans - 8:20 pm ET 

Notable Injuries

 

Must-Starts for Fantasy Football Lineups

A.J. Brown (WR, TEN): He’s back baby. Well, hopefully he is back. After being activated from the Injured Reserve earlier this week, all signs are pointing in the right direction. The young superstar has been very disappointing for fantasy this season. Not only has he missed a significant portion of the season due to injuries, but he also had five of his nine games under 10 fantasy points. Thankfully we have seen stretches this season that showcase the upside of Brown, with two consecutive weeks with 130+ receiving yards and a score. The Titans are taking on a 49ers team that ranks 11th in fantasy points allowed to the position. The Titans offense has been struggling, and Brown just might be the spark they need to get back on track. I would start AJB as a solid WR1 this week.

UPDATE: A.J. Brown has officially been activated from IR and will return this week.

Deebo Samuel (WR, SF): Speaking of WR1’s, holy smokes is Deebo Samuel having a year. Whether he is a receiver or running back, Samuel has become the best in the league at yards after the catch. He is currently the WR2 on the season and has the second most touchdowns at the position. In both of the categories, he is only trailing Cooper Kupp and of his 12 touchdowns, seven are rushing touchdowns. With the 49ers backfield being a revolving door, Samuel has become not only their leading receiver but the team's lead back when necessary. Samuel is one of the most versatile players in the league and should continue to carry your fantasy team this week against the team that allows the second-most fantasy points to the WR position. 

George Kittle (TE, SF): Here we transition from one yards after the catch monster to another. Ironically on the same team, Kittle has put his athletic abilities on full display these last few weeks. Since returning from injury, Kittle has been on a tear. Over this seven-week period, he only has one week below ten fantasy points, averaging 89 receiving yards and 0.86 touchdowns. Oh, and also he is the TE-one over the last seven weeks. Unless you are against Andrews or Kelce, Kittle is a massive fantasy advantage at the position. I would look for him to continue his dominance in this good matchup. 

 

Solid Options for Fantasy Football Lineups

D'Onta Foreman (RB, TEN): From the depths of the fantasy underworld, Foreman has resurfaced himself and taken over one of the league’s most prolific rushing offenses. For those of you who believe his resurgence has come out of nowhere, here is a little history. The 2016 Doak Walker Award Winner (given to the best college running back) entered the league with a lot of buzz. After being drafted to the Texans in 2017 in the third round, he found himself sitting behind the veteran Lamar Miller. In his limited work, he displayed explosiveness and promise. Unfortunately with an Achilles tear in 2018, he found himself being picked up by the Colts off of waivers in 2019. He then had to leave after tearing his bicep in the preseason and tried out for the Titans in 2020. Flash forward to now, and we have ourselves the RB10 over the last two weeks. All of that was to say that this kid had promise and has had to overcome devastating injuries. Over his last three games, he has 100 yards rushing twice and found the endzone in the third game. If you managed to pick him up from your waivers you are most likely playing him out of necessity, however, he is a solid play against a mild-tier 49er run defense. 

Jimmy Garoppolo (QB, SF): Since Week 12, Jimmy G has quietly snuck his way into the QB-one category. Over these last three games, he is the QB11 and is the QB18 on the season. In the last four games, he has torched teams for 230+ yards in each game, including two games narrowly missing the 300-yard mark. When you have weapons like Samuel and Kittle, managers have been relieved to see the veteran QB start airing out the ball. Tennessee's defense is in the top half in most points allowed to the QB position this season. If you are desperate for a playoff QB or need a solid QB-two this week, Jimmy Garoppolo is a solid play this Thursday.

 

Flex Considerations for Fantasy Football Lineups

Ryan Tannehill (QB, TEN): Unfortunately, Tannehill just hasn’t been cutting it for fantasy teams. It’s hard to blame the veteran after losing key players in Derrick Henry, A.J. Brown, and Julio Jones for most of the year. It came as no surprise that losing Henry slowed the entire fantasy offense, but ironically, the loss of the star running back has impacted Tannehill the most. Failing to score 10 fantasy points in three of his last four games, it’s hard to trust Tannehill this week. Thankfully, he possesses upside with his legs, as he has scored twice on the ground over the last two weeks. Plus, the return of A.J. Brown does spark some optimism. However, he is no more than a high-upside/low-floor play this week against a very solid 49ers defense.

Brandon Aiyuk (WR, SF): If there was an award for the scariest player to start in fantasy, Aiyuk would have to be in the running. After being praised all offseason, he literally disappeared at the start of the season. Then, seemingly out of the blue, he started seeing starter snap counts and six or more targets in six of the last eight games. Then, once you finally feel comfortable playing him, he catches one of two targets for 36 yards against a poor Falcons secondary last week. Thankfully he gets the chance to redeem himself against another exploitable opponent. The Titans are allowing the second-most fantasy points to the position and could provide some life for the young receiver. However, because we saw a good matchup last week and it did not translate for Aiyuk’s fantasy success, he is hard to trust as more than a high-upside flex play this week.

 

Consider Sitting for Fantasy Football Lineups

Jeff Wilson Jr. (RB, SF): Yes, Elijah Mitchell has been ruled out. Yes, Wilson Jr. is coming off a monster game. No, I don’t think you should play him if you have other alternative options. Well, at least I think you should be careful if you do decide to start him. This “sit” is a result of Tennessee being the best fantasy defense against running backs on the season. They have managed to shut down the run all season, and that continued last week as they stiffed Najee Harris. Wilson Jr. finally had the game managers had been waiting for, however, I don’t want to rely on one good performance in the fantasy playoffs, especially against a very tough opponent. I would look elsewhere this week if possible.

Other Titans pass-catchers: Whether you are holding onto Julio Jones or are taking a shot at Anthony Firkser, Nick Westbrook-Ikhine, or Chester Rogers, I don’t think you can play any of them this week. Not only have the 49ers been very solid on defense these last few weeks, but these players also have not been reliable for fantasy. Although it is tough to sit Julio Jones if he is active, I would not want to risk the possibility of reinjury this week. My favorite player of this group has to be Westbrook-Ikhine as he has seen six or more targets in three of the last four games, but I would try to find the higher upside in another flyer this week.

 

As soon as we were heating up, we cooled right down. Thanks to a massive fourth quarter and an overtime touchdown, we missed on both of our picks last week. Nevertheless, we go into this week with fresh eyes. The Titans have been playing miserable football recently, while the 49ers could be argued to be one of the hottest teams in the league right now. Additionally, with the Titan's lack of passing defense and desperation to turn their season around at home, this could be a fun game to start Week 16. I wish you all the best of luck this week and happy holidays! 

Ellis’ Picks: 49ers -3.0 (12-5), Over 44.0 (11-6)

Career record: Spread (21-14), Over/Under (20-15)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Juraj Slafkovsky

Ends Point Drought in Game 1 Loss
Bowen Byram

Ties Franchise Record With Fourth Postseason Goal
Zach Benson

Posts Second Consecutive Multi-Point Game
Rasmus Dahlin

"Seems Fine" After Early Exit on Wednesday
Sam Merrill

Listed as Questionable for Thursday
Geno Smith

Frank Reich Says Geno Smith is the "Perfect Fit" for his Offense
Aaron Rodgers

Cardinals Interest in Aaron Rodgers Isn't Real
Luke Kennard

Tagged as Questionable for Game 2 Against Thunder
Travis Hunter

Expected to Play Both Ways in Year 2
Jarred Vanderbilt

Considered Doubtful for Thursday
Jalen Williams

Still Out Thursday
Carter Bryant

Available Wednesday Night
Luka Dončić

Luka Doncic Reveals Recovery Timeline
Anthony Edwards

Cleared for Game 2 Against Spurs
Mitchell Robinson

is Ruled Out for Game 2 on Wednesday
Kevin Huerter

is Doubtful for Game 2 on Thursday
Brandon Miller

has Successful Shoulder Surgery
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Ayo Dosunmu

is Cleared to Play in Game 2
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Joel Embiid

is Downgraded to Out for Game 2
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Nils Hoglander

Will Miss World Championship Due to Injury
Christian Dvorak

Likely to Play in Game 3 Against Hurricanes
Owen Tippett

a Game-Time Decision Thursday
Noah Cates

to Miss Rest of Round 2
Arber Xhekaj

Rejoins Canadiens Lineup Wednesday
Brendan Gallagher

Scratched on Wednesday
Logan Stanley

Returns to Action Wednesday
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
Russell Wilson

Jets Offer a Contract to Russell Wilson
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
C.J. Stroud

Makes Changes to his Diet as he Looks to Bounce Back
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
Bhayshul Tuten

the Preferred Dynasty Running Back in Jacksonville?
CFB

Tanook Hines Stepping into WR1 Role for USC
De'Zhaun Stribling

49ers See Something Special in De'Zhaun Stribling
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Joe Mixon

Remains an Enormous Question Mark
RJ Harvey

Still the Leader in a Crowded Backfield?
Carlos Correa

to Have Season-Ending Ankle Surgery
Baker Mayfield

Looking to Bounce Back in Contract Year
Brian Robinson Jr.

a Dynasty Target as Handcuff with Standalone Upside
Sam LaPorta

Remains an Intriguing Dynasty Target Post-Injury
Minnesota Vikings

Vikings Request to Interview Terrance Gray for GM Job
Kenneth Walker III

Could be More Involved as Pass-Catcher With Chiefs
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Jakobi Meyers

Is Jakobi Meyers the Most Mispriced Jaguars Receiver in Dynasty Leagues?
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Jayden Higgins

How Much Growth Can be Expected of Jayden Higgins in Year 2?
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
D'Andre Swift

an Underrated Dynasty Buy for Contending Managers
Adam Scott

Brings Strong Form to Quail Hollow
Woody Marks

A Role Change Could Be Key to Salvaging Woody Marks' Dynasty Value
Robert MacIntyre

a Steady Option at Truist Championship
Ray Davis

Offers Almost No Standalone Value as a Fading Dynasty Asset
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Chet Holmgren

Leads Thunder to Victory in Game 1 Against Lakers
LeBron James

Scores Game-High 27 Points in Tuesday's Loss
James Harden

Finishes Game 1 Loss With 22 Points
Cade Cunningham

Posts 23 Points in Game 1 Win
Jalen Duren

Records Second Consecutive Double-Double
Sam Merrill

Status Unclear for Game 2
Jarred Vanderbilt

Dislocates Finger in Game 1 Loss
Mats Zuccarello

Extends Point Streak to Five Games
Kirill Kaprizov

Nets Third Playoff Goal
Scott Wedgewood

Returns to Form in Game 2 Against Wild
Gabriel Landeskog

Picks Up Two Power-Play Points Tuesday
Martin Necas

Has Second Straight Multi-Point Outing
Nathan MacKinnon

Joins Exclusive List With Another Three-Point Performance
TOR

Maple Leafs Win Draft Lottery
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Stefon Diggs

Found Not Guilty of Assault, Strangulation
Emilio Pagán

Emilio Pagan Carted Off With Apparent Hamstring Injury on Tuesday
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Merrill

Heads to Locker Room in Game 1
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Anthony Edwards

Iffy for Game 2
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
MLB

Cardinals-Brewers Game Postponed on Tuesday
Roman Anthony

Day-to-Day With Wrist Sprain
Radko Gudas

to Remain Sidelined Wednesday
Sam Carrick

Upgraded to Day-to-Day
Noah Cates

Considered Day-to-Day
Travis Kelce

Dynasty Value Fading Entering 2026
Jacob Misiorowski

"All Things Look Good" for Jacob Misiorowski to Start on Wednesday
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
MLB

Rockies-Mets Game Postponed Due to Inclement Weather
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
Raisel Iglesias

Braves Officially Reinstate Raisel Iglesias From Injured List on Tuesday
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Roman Anthony

Pulled Early on Monday After Tweaking his Wrist
Jhoan Duran

to Come Off the Injured List on Tuesday
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
Jack Della Maddalena

Returns At UFC Perth
Carlos Prates

Set For UFC Perth Main Event
Quillan Salkilld

Set For Co-Main Event
Beneil Dariush

An Underdog At UFC Perth
Steve Erceg

Looks To Win Back-To-Back Fights
Tim Elliott

Looks For His Third Consecutive Win
Ollie Schmid

Set For His UFC Debut
Marwan Rahiki

Looks To Remain Undefeated
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF