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Sep 16, 2026, 5:27 PM ET

New Orleans Saints veteran running back Alvin Kamara (knee) will make his season debut in the Week 2 game on the road in Baltimore against the Ravens, head coach Kellen Moore told Matthew Paras of The New Orleans Times-Picayune. After dealing with an MCL sprain in his knee for most of training camp in the summer, the Saints held Kamara out of their Week 1 season-opening loss to the Detroit Lions in overtime, but he is ready to go now after practicing in full on Wednesday. It is bad news for fantasy managers who might have picked up Kendre Miller off waivers this week, and it is also bad news for the fantasy ceiling of RB1 Travis Etienne Jr., who underwhelmed in his Saints debut in the season opener with only nine carries for 46 yards and seven catches for 32 yards. While Kamara is expected to play this weekend, do not be surprised if the Saints ease him back into the fold, which will make him a pretty volatile RB3/flex option in PPR formats. When fully healthy, Kamara is expected to take a back seat to Etienne in 2026 and mostly serve as the primary third-down pass-catcher out of the backfield.--Keith Hernandez
Source: The New Orleans Times-Picayune - Matthew Paras
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Sep 16, 2026, 5:00 PM ET

Green Bay Packers running back MarShawn Lloyd was not particularly efficient in his team's Week 1 loss to the Minnesota Vikings, recording 13 carries for 37 yards. However, Lloyd finished the game with nearly double the number of carries as Packers RB2 Chris Brooks (seven). Based on the workload distribution in the season opener, Lloyd may be in position to lead the Green Bay backfield while star Packers back Josh Jacobs remains on the NFL's Commissioner's Exempt List due to an offseason arrest. While the Packers struggled to run the ball against Minnesota, the team has easier matchups on paper in the next couple of weeks against the New York Jets and the Atlanta Falcons. As long as Lloyd continues to see the majority of Green Bay's rushing work, he carries upside for fantasy managers.--Will Brady
Source: RotoBaller
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Sep 16, 2026, 4:48 PM ET

Chicago Bears running back Kyle Monangai (hamstring) was a limited participant in his team's practice on Wednesday. The 24-year-old missed time during training camp with a knee injury, but he returned in time for Week 1 and recorded 124 scrimmage yards and a touchdown on 12 touches in his team's blowout win over the Carolina Panthers. The severity of Monangai's hamstring issue is not yet clear, but it appears the young running back is now dealing with another lower-body ailment. Bears RB1 D'Andre Swift (ankle/knee) was also limited in practice on Wednesday due to ankle and knee injuries. If Swift is out and Monangai is able to play in Week 2 against the Minnesota Vikings, Monangai would immediately vault into must-start territory for fantasy managers. If Swift and Monangai end up missing time, Bears RB3 Roschon Johnson would likely be in line for a significant workload increase.--Will Brady
Source: Chicago Bears
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Sep 16, 2026, 4:38 PM ET

Chicago Bears running back D'Andre Swift (ankle/knee) was a limited participant in his team's practice on Wednesday due to ankle and knee ailments. The 27-year-old is coming off a monster performance in Week 1, recording 134 scrimmage yards and three touchdowns on 19 touches in his team's 59-37 win over the Carolina Panthers. The severity of Swift's injuries is unclear, but his practice status will be something for fantasy managers to monitor ahead of Chicago's Week 2 matchup against the Minnesota Vikings on Sunday. Bears RB2 Kyle Monangai (hamstring) was also limited in practice on Wednesday with a hamstring injury. If both of Chicago's top rushers are unable to play against Minnesota, Bears running back Roschon Johnson could be in line for a significant workload increase.--Will Brady
Source: Chicago Bears
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Sep 16, 2026, 4:32 PM ET

Atlanta Falcons quarterback Michael Penix Jr. (knee) split first-team reps with fellow Falcons QB Cooper Rush on Wednesday, per Cameron Wolfe of NFL Network. Penix Jr. is working his way back from the knee injury that ended his 2025 season. Wolfe reports that Penix Jr. is "close" to a return and has not yet ruled out playing in Week 2 against the Carolina Panthers. Across nine starts in 2025, the 26-year-old completed 60.1% of his pass attempts for 1,982 yards, nine touchdowns, and three interceptions. While Penix Jr. profiles as a borderline top-24 fantasy quarterback at best, his return would represent a major upgrade in quarterback play for Falcons pass-catchers like wide receiver Drake London and tight end Kyle Pitts Sr. A third Falcons quarterback, Tua Tagovailoa (oblique), is also reportedly improving from the oblique injury that sidelined him in Week 1 and could be in the mix to start in Week 2 if Penix Jr. remains out.--Will Brady
Source: NFL Network - Cameron Wolfe
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Sep 16, 2026, 4:24 PM ET

Detroit Lions quarterback Jared Goff did not have his most efficient day in his team's Week 1 overtime win over the New Orleans Saints, completing 26 of 39 pass attempts for 206 yards, two touchdowns, and zero interceptions. However, Goff remains at the helm of a Lions offense that has multiple dangerous pass-catchers in wide receivers Amon-Ra St. Brown and Jameson Williams, as well as tight end Sam LaPorta and running back Jahmyr Gibbs. Fantasy managers may also have reason to believe that Goff and the Lions will be in lots of pass-heavy game scripts going forward. Detroit's defense remains without both starting safeties and allowed Saints quarterback Tyler Shough to throw for over 400 yards and three touchdowns in Week 1. As long as Goff continues to throw 35-plus pass attempts per game, he should be in position to produce for fantasy managers.--Will Brady
Source: RotoBaller
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Sep 16, 2026, 4:14 PM ET

Baltimore Ravens tight end Mark Andrews put together a solid performance in his team's 41-23 Week 1 win over the Indianapolis Colts, recording four catches for 49 yards on six targets. The 31-year-old had the least productive season of his career in 2025, recording just 48 catches for 422 yards and five touchdowns across 17 games. However, Andrews' playing time outlook is much improved in 2026 following the offseason departure of former Ravens and current New York Giants tight end Isaiah Likely. Coming out of Week 1, Andrews may be in an even more favorable position to rack up targets. Baltimore placed rookie wide receiver Ja'Kobi Lane (wrist) on Injured Reserve, and star wideout Zay Flowers (hamstring) did not practice on Wednesday due to a hamstring injury. Heading into his Week 2 matchup against the New Orleans Saints, Andrews could be moving towards must-start territory.--Will Brady
Source: RotoBaller
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Sep 16, 2026, 4:09 PM ET

San Francisco 49ers tight end Jake Tonges (knee) is done for the season after surgery to repair a torn MCL, according to Cam Inman. The 49ers had already placed Tonges on injured reserve Wednesday, but the surgery takes a return later this year off the table. He suffered the injury during the season-opening win over the Rams and did not record a catch before leaving. Tonges had moved into the No. 2 tight end spot behind George Kittle after catching 34 passes for 293 yards and five touchdowns last season. San Francisco now has Luke Farrell and Brayden Willis behind Kittle and also added veteran Jack Stoll to the practice squad. Farrell and Willis are the names to watch if the 49ers need more work from the position behind Kittle.--Bruno Mulé
Source: Cam Inman
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Sep 16, 2026, 3:54 PM ET

San Francisco 49ers wide receiver De'Zhaun Stribling (ankle) underwent surgery Wednesday and is expected to miss around 10 weeks, according to Cam Inman. Head coach Kyle Shanahan said the 49ers are still hoping Stribling can make it back before the season ends. The rookie had already been placed on injured reserve after suffering a deltoid sprain in the season-opening win over the Rams, but the original outlook was considerably shorter before surgery became necessary. Stribling played 21 offensive snaps in his NFL debut and did not draw a target before leaving. San Francisco used the 33rd overall pick on him in April, so the long-term interest hasn't gone anywhere, but most redraft managers don't need to wait through a 10-week absence. He remains an easy hold in dynasty leagues while the 49ers hope to get him back late in the season.--Bruno Mulé
Source: Cam Inman
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Sep 16, 2026, 3:51 PM ET

Cincinnati Bengals quarterback Joe Burrow (back) said he is dealing with some back tightness and soreness from the Week 1 season-opening win over the Tampa Bay Buccaneers on Sunday, according to Paul Dehner Jr. of The Athletic. Burrow said that he will be fine and expects to play. On the idea that he would not play in Week 2 against the Houston Texans out of precaution, Burrow said, "That's ridiculous." The star signal-caller did not do much throwing during practice on Wednesday and also did not stretch with the rest of the team, which was the first sign that he was dealing with something. He will most likely be listed as limited on Wednesday's injury report. As long as Burrow does not get worse over the next couple of days, he should be fine to suit up this weekend on the road in a difficult matchup against a Texans team that took the Buffalo Bills to the wire in Week 1. The 29-year-old three-time Pro Bowler threw for 254 yards, one touchdown, and one interception in the 33-27 Week 1 win over Tampa, and he will be a must-start in fantasy lineups as long as he is active this Sunday.--Keith Hernandez
Source: The Athletic - Paul Dehner Jr.
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Sep 16, 2026, 3:42 PM ET

Minnesota Vikings head coach Kevin O'Connell said that quarterback Kyler Murray (concussion) will be a limited participant in Wednesday's practice, according to Dane Mizutani of the St. Paul Pioneer Press. Murray played only 11 snaps in his Vikings debut in the Week 1 season-opening win over the Green Bay Packers on Sunday before suffering a scary concussion in the first quarter. He was quickly ruled out and placed in the concussion protocol, putting his status up in the air for Week 2 this Sunday against the division-rival Chicago Bears. Murray was in good spirits in the team's locker room after Sunday's game, and a limited first practice of the week is a good sign, but it does not guarantee that the former Arizona Cardinals QB will return this weekend. Veteran Carson Wentz did an admirable job leading Minnesota to a come-from-behind victory over the Packers while throwing three touchdowns, so O'Connell could be content to give him a start and let Murray rest up for another week. Murray will almost certainly need to upgrade to a full practice this week to be cleared from the league's concussion protocol.--Keith Hernandez
Source: St. Paul Pioneer Press - Dane Mizutani
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Sep 16, 2026, 3:37 PM ET

Baltimore Ravens wide receiver Ja'Kobi Lane (wrist) is being placed on injured reserve after undergoing surgery Wednesday, according to Ian Rapoport. Lane fractured his wrist in Sunday's win over Indianapolis and will now miss at least four games. The rookie had worked his way into Baltimore's No. 3 receiver role before the injury and caught one of three targets for 11 yards in his NFL debut. He also had a touchdown wiped out by a holding penalty. The Ravens are expected to promote Chris Moore from the practice squad to take Lane's roster spot, while Devontez Walker and Elijah Sarratt are also candidates for more work while he is out. Lane is worth keeping in an IR spot in dynasty and deeper leagues, but redraft managers without one do not need to hold him through the absence.--Bruno Mulé
Source: RotoBaller
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Sep 16, 2026, 3:31 PM ET

Seattle Seahawks quarterback Sam Darnold (glute) has officially been ruled out for Sunday's game against the Arizona Cardinals, according to James Palmer. Head coach Mike Macdonald also said the Seahawks still have no plans to place Darnold on injured reserve. Seattle has described the issue as an unusual soft-tissue injury, but the hip joint itself is unaffected and the team considers the injury short-term. Darnold lasted only five plays in the opener against New England, completing one of two passes for 13 yards before leaving. Drew Lock took over and went 16-of-22 for 187 yards and a touchdown in the 13-10 comeback win. He is in line to start Sunday while Darnold continues to recover. There is still no firm date for Darnold's return, but keeping him off injured reserve leaves open the possibility that he could be back within the next few weeks.--Bruno Mulé
Source: James Palmer
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Sep 16, 2026, 3:20 PM ET

Los Angeles Chargers wide receiver Ladd McConkey (ribs) did not practice Wednesday, according to Alex Insdorf. McConkey is still considered day-to-day after getting hurt during Sunday's loss to Arizona, when he caught five passes for 82 yards and a touchdown before leaving in the third quarter. Earlier reporting indicated the injury was not believed to be significant, but sitting out the first practice of Week 2 leaves his availability against Las Vegas unsettled. McConkey and Quentin Johnston remain the Chargers' starting receivers, with Tre' Harris among the options behind them. Los Angeles is already without Keandre Lambert-Smith, who landed on injured reserve Tuesday. There is still plenty of time for McConkey to get back on the field before Sunday, so Wednesday's absence alone isn't reason to panic. His status Thursday and Friday should give fantasy managers a much better idea of whether he can play in Week 2.--Bruno Mulé
Source: Alex Insdorf
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Sep 16, 2026, 3:13 PM ET

Minnesota Vikings running back Demond Claiborne was a healthy scratch in Week 1, but his fantasy situation changed quickly this week. Jordan Mason is headed to short-term injured reserve with a fractured thumb after handling 15 carries in Sunday's win over Green Bay, leaving a meaningful chunk of the backfield workload up for grabs. Claiborne was already the only running back listed behind Aaron Jones Sr. and Mason on Minnesota's Week 1 depth chart, and the Vikings traded up to select him in the sixth round this spring. There is no guarantee those missing carries immediately become his. DeeJay Dallas dressed ahead of Claiborne in the opener, and Minnesota could lean on the veteran while the rookie works his way into the offense. The opening is still much larger than it was a few days ago. Claiborne went from being buried behind two established backs to having a realistic path toward offensive touches, making him one of the more interesting fantasy stashes coming out of Week 1.--Bruno Mulé
Source: RotoBaller

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