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FanDuel MLB DFS Lineup Picks (9/25/19): Daily Fantasy Baseball Advice

Joel Bartilotta highlights the top FanDuel MLB DFS lineup picks for 9/25/19, and a couple of sleepers to consider while building daily rosters.

We do have three day-games for this Wednesday slate and we’ll try to offer up a couple of plays from that slate to cater to all of you readers. It happens to be the final Wednesday article of the regular season and it’s been a treat helping you guys out all season! 

I just wanted to thank all of you for reading throughout the year, so let's finish strong!

Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @Bartilottajoel

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

FanDuel DFS Pitchers

Shane Bieber, CLE at CWS ($11,500) 

Bieber is truly one of the best pitchers in the AL. That’s evident when you see his 3.23 ERA, 1.03 WHIP, and 30.3 percent K rate, with much of that damage coming in the second half. Over his last 12 starts, Bieber is pitching to a 2.56 ERA, 1.01 WHIP, and 10.2 K/9 rate. All of those are scary numbers for an offense like this, with the White Sox ranked 24th in runs scored, 25th in K rate and 22nd in xwOBA. They’re even worse against righties, sending out hitters like Jose Abreu, Eloy Jimenez, James McCann, and Tim Anderson from the right side to oppose Bieber. All of this has the Indians entering this matchup as a –300 favorite.

Zack Greinke, HOU at SEA ($9,400) 

Greinke hasn’t quite been himself since joining the Astros but he’s still one of the best pitchers around. That’s clear when you see his 3.05 ERA and 1.01 WHIP. Those stellar numbers would put him in play against almost anyone but especially the Mariners. Not only does Seattle rank 28th in K rate, but they also sit 26th in xwOBA. Those statistics make it no surprise that this is one of the five-worst clubs in baseball since the opening month and even less surprising that Greinke enters this matchup as a –350 favorite.

 

FanDuel DFS Infielders

C.J. Cron – 1B, MIN at DET ($3,200) 

It’s amazing to see Cron’s price this low in such a good situation. The simple fact is, this dude is one of the best hitters in the Majors when he faces a lefty. That’s evident when you see his .381 OBP, .640 SLG and 1.021 OPS with the platoon advantage in his favor this season. It’s not like he has to face a tough lefty here either, with the Motor City Kitties sending out Daniel Norris and his 4.58 ERA and 1.34 WHIP. Those ugly numbers from Norris have the Twins projected for more than five runs and we anticipate Cron being a major part of that damage.

Ozzie Albies – 2B, ATL at KC ($3,700) 

This kid got a lot of crap for his team-friendly contract but he’s showing people that he means business no matter how much is on his paycheck. Over his last 21 games, Albies is hitting .387 while providing a .642 SLG and 1.069 OPS. He actually has an OPS approaching 1.000 dating all the way back to the beginning of June and it’s becoming evident that he’s one of the best second basemen in our sport. Getting to face Mike Montgomery's 5.00 ERA and 1.61 WHIP is simply the icing on the cake, with Albies generating a .390 AVG, .695 SLG and 1.103 OPS against lefties so far this year.

Alex Bregman – 3B, HOU at SEA ($4,400) 

Bregman has been the best player in baseball the last two months and it’s going to be tough to fade him in this brilliant situation. Let’s begin with this matchup, as he faces Yusei Kikuchi and his 5.55 ERA and 1.54 WHIP. That happens to give Bregman the platoon advantage, with the slugging third baseman amassing a 1.102 OPS against them this season. Not to mention, Bregman has a .373 AVG, .480 OBP, .745 SLG, and 1.225 OPS over his last 45 games played.

Jonathan Villar – SS, BAL at TOR ($3,600) 

It’s truly incredible how good Villar has been this season. He’s actually Top-5 in season-long leagues, thanks to a ridiculous second half. Over his last 55 games played, Villar has a .315 AVG, .387 OBP, .557 SLG, and .944 OPS. Those look like the numbers of an elite power hitter but he’s actually batting leadoff and has provided 21 steals in that span as well. That’s a nightmare for a guy like Jacob Waguespack, with the Toronto righty pitching to a 4.75 ERA and 1.36 WHIP.

 

FanDuel DFS Outfielders

Nelson Cruz, MIN at DET ($4,300) 

It’s crazy to see a 39-year-old mash baseballs like this guy does. It’s very reminiscent of David Ortiz near the end of his career and it’s clear Cruz has found the fountain of youth. Let’s take a look at his bonkers statistics, with Cruz being one of the league leaders with a .631 SLG and 1.018 OPS. Those are epic numbers and it doesn’t even take into consideration that he has a .402 OBP, .755 SLG and 1.156 OPS against left-handers this season. That’s terrifying news for Daniel Noris’ ugly numbers from the Cron write-up.

Tommy Pham, TB vs. NYY ($3,900) 

The Yankees are sending out J.A. Happ and that means we have to stack some Rays against him. The reason for that is because the NY southpaw is currently pitching to a 5.01 ERA and 1.30 WHIP this season. Those numbers are right up Pham’s alley, with the versatile outfielder accumulating a .467 OBP and .944 OPS against lefties so far this season.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Artturi Lehkonen

Expected to Play Wednesday Night
Cale Makar

Will Miss Game 1 Against Golden Knights
Malachi Fields

Appears Well-Positioned for Rookie Year Breakout in New York
Aaron Rodgers

Plans to Retire Following 2026 Season
Anthony Richardson Sr.

Is Anthony Richardson Sr. Worth Buying Low on in Deeper Dynasty Formats?
DJ Giddens

Does DJ Giddens Carry Dynasty Buy-Low Appeal into 2026?
AJ Barner

Enters 2026 as a Dynasty Sell-High Candidate
Josh Jacobs

Is Josh Jacobs at the Peak of His Dynasty Value?
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Wilson

Cardinals Interested in Inking Michael Wilson to a Long-Term Extension
Kyle Williams

Bulks Up, Ready to Make Year 2 Leap
Deshaun Watson

the First QB Up During OTA Drills on Wednesday
Quinshon Judkins

Taking Part in 11-on-11 Drills
Xavier Legette

Fighting for His Future in Carolina?
Brian Thomas Jr.

Jaguars Not Expected to Trade Brian Thomas Jr.
Rashod Bateman

Future in Baltimore is Bleak
Mark Andrews

Poised to Bounce Back in 2026?
Tyrone Tracy Jr.

Is Tyrone Tracy Jr. a Sneaky Dynasty Buy?
Chimere Dike

Dynasty Managers Compelled to Hold Chimere Dike?
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Jameson Williams

a High-Ceiling Buy for Risk-Tolerant Dynasty Managers
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Chase Brown

a Short-term Dynasty Buy Whose Value Could Extend Beyond 2026
Tony Finau

Looking for Consistency at TPC Craig Ranch
J.K. Dobbins

Becoming an Underpriced Starting Running Back
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Rome Odunze

Has Ambiguity Among Bears WRs Created Buying Opportunity for Rome Odunze?
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Marvin Mims Jr.

Dynasty Value Hurt by Lack of a Defined Role
Si Woo Kim

Looks To Stay Hot at CJ Cup
James Harden

Struggles in Eastern Conference Finals Opener
Evan Mobley

Bags Second Consecutive Double-Double
Donovan Mitchell

Produces Top Two-Way Performance in Game 1 Loss
OG Anunoby

Plays Key Role in Comeback Win
Mikal Bridges

Remains Efficient in Game 1 Against Cavaliers
Karl-Anthony Towns

Extends Double-Double Streak to Four Games
Jalen Brunson

Leads Knicks to Historic Comeback Win
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Dean Wade

Returns to Starting Unit Tuesday
OG Anunoby

Starting on Tuesday
Tobias Harris

May Remain in Motown
Jalen Duren

Pistons Eager to Keep Jalen Duren
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Dallas Mavericks

Jason Kidd Fired as Mavericks Head Coach
De'Aaron Fox

Officially Listed as Questionable for Game 2 Against Thunder
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Victor Wembanyama

Dominates Game 1 Against Thunder
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Quinn Hughes

Open to Signing Extension This Offseason
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Sam Malinski

Practices Fully Sunday
Josh Manson

Rejoins Practice
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF