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FanDuel MLB DFS Lineup Picks (9/25/19): Daily Fantasy Baseball Advice

Joel Bartilotta highlights the top FanDuel MLB DFS lineup picks for 9/25/19, and a couple of sleepers to consider while building daily rosters.

We do have three day-games for this Wednesday slate and we’ll try to offer up a couple of plays from that slate to cater to all of you readers. It happens to be the final Wednesday article of the regular season and it’s been a treat helping you guys out all season! 

I just wanted to thank all of you for reading throughout the year, so let's finish strong!

Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @Bartilottajoel

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FanDuel DFS Pitchers

Shane Bieber, CLE at CWS ($11,500) 

Bieber is truly one of the best pitchers in the AL. That’s evident when you see his 3.23 ERA, 1.03 WHIP, and 30.3 percent K rate, with much of that damage coming in the second half. Over his last 12 starts, Bieber is pitching to a 2.56 ERA, 1.01 WHIP, and 10.2 K/9 rate. All of those are scary numbers for an offense like this, with the White Sox ranked 24th in runs scored, 25th in K rate and 22nd in xwOBA. They’re even worse against righties, sending out hitters like Jose Abreu, Eloy Jimenez, James McCann, and Tim Anderson from the right side to oppose Bieber. All of this has the Indians entering this matchup as a –300 favorite.

Zack Greinke, HOU at SEA ($9,400) 

Greinke hasn’t quite been himself since joining the Astros but he’s still one of the best pitchers around. That’s clear when you see his 3.05 ERA and 1.01 WHIP. Those stellar numbers would put him in play against almost anyone but especially the Mariners. Not only does Seattle rank 28th in K rate, but they also sit 26th in xwOBA. Those statistics make it no surprise that this is one of the five-worst clubs in baseball since the opening month and even less surprising that Greinke enters this matchup as a –350 favorite.

 

FanDuel DFS Infielders

C.J. Cron – 1B, MIN at DET ($3,200) 

It’s amazing to see Cron’s price this low in such a good situation. The simple fact is, this dude is one of the best hitters in the Majors when he faces a lefty. That’s evident when you see his .381 OBP, .640 SLG and 1.021 OPS with the platoon advantage in his favor this season. It’s not like he has to face a tough lefty here either, with the Motor City Kitties sending out Daniel Norris and his 4.58 ERA and 1.34 WHIP. Those ugly numbers from Norris have the Twins projected for more than five runs and we anticipate Cron being a major part of that damage.

Ozzie Albies – 2B, ATL at KC ($3,700) 

This kid got a lot of crap for his team-friendly contract but he’s showing people that he means business no matter how much is on his paycheck. Over his last 21 games, Albies is hitting .387 while providing a .642 SLG and 1.069 OPS. He actually has an OPS approaching 1.000 dating all the way back to the beginning of June and it’s becoming evident that he’s one of the best second basemen in our sport. Getting to face Mike Montgomery's 5.00 ERA and 1.61 WHIP is simply the icing on the cake, with Albies generating a .390 AVG, .695 SLG and 1.103 OPS against lefties so far this year.

Alex Bregman – 3B, HOU at SEA ($4,400) 

Bregman has been the best player in baseball the last two months and it’s going to be tough to fade him in this brilliant situation. Let’s begin with this matchup, as he faces Yusei Kikuchi and his 5.55 ERA and 1.54 WHIP. That happens to give Bregman the platoon advantage, with the slugging third baseman amassing a 1.102 OPS against them this season. Not to mention, Bregman has a .373 AVG, .480 OBP, .745 SLG, and 1.225 OPS over his last 45 games played.

Jonathan Villar – SS, BAL at TOR ($3,600) 

It’s truly incredible how good Villar has been this season. He’s actually Top-5 in season-long leagues, thanks to a ridiculous second half. Over his last 55 games played, Villar has a .315 AVG, .387 OBP, .557 SLG, and .944 OPS. Those look like the numbers of an elite power hitter but he’s actually batting leadoff and has provided 21 steals in that span as well. That’s a nightmare for a guy like Jacob Waguespack, with the Toronto righty pitching to a 4.75 ERA and 1.36 WHIP.

 

FanDuel DFS Outfielders

Nelson Cruz, MIN at DET ($4,300) 

It’s crazy to see a 39-year-old mash baseballs like this guy does. It’s very reminiscent of David Ortiz near the end of his career and it’s clear Cruz has found the fountain of youth. Let’s take a look at his bonkers statistics, with Cruz being one of the league leaders with a .631 SLG and 1.018 OPS. Those are epic numbers and it doesn’t even take into consideration that he has a .402 OBP, .755 SLG and 1.156 OPS against left-handers this season. That’s terrifying news for Daniel Noris’ ugly numbers from the Cron write-up.

Tommy Pham, TB vs. NYY ($3,900) 

The Yankees are sending out J.A. Happ and that means we have to stack some Rays against him. The reason for that is because the NY southpaw is currently pitching to a 5.01 ERA and 1.30 WHIP this season. Those numbers are right up Pham’s alley, with the versatile outfielder accumulating a .467 OBP and .944 OPS against lefties so far this season.

MLB DFS News and Injury Alerts




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NFL

Chiefs Talking with Cardinals About the No. 3 Pick
Carson Beck

Steelers Eyeing Carson Beck in the Draft?
Thomas Bryant

to Remain Out Monday
Juan Soto

is on Track to Return Next Homestand
Cade Cunningham

Playing Without Minutes Restriction Sunday
Corbin Carroll

Exits Sunday's Game with Back Tightness
OG Anunoby

Tagged as Probable for Monday
Onyeka Okongwu

Might Miss Game 2 Against Knicks
Immanuel Quickley

Questionable for Game 2
Jordan Goodwin

Ruled Out for Rest of Game 1
Jonathan Isaac

Ruled Out for Sunday
Desmond Bane

Available for Game 1
Artem Zub

Uncertain for Game 2
Karel Vejmelka

Makes Playoff Debut Sunday
Carter Hart

in Vegas Crease for Playoff Opener
Jeremy Swayman

Begins Fifth Postseason Campaign
Alex Lyon

Available for Game 1
Dominic James

Activated From Injured Reserve
NFL

Zachariah Branch Arrested for Misdemeanor Obstruction
New York Giants

Sonny Styles One of the Top Targets for Giants at No. 5 in NFL Draft
Renardo Green

49ers Looking to Trade Renardo Green?
Keenan Allen

Chargers Not Closing the Door on a Reunion With Keenan Allen
Grayson Allen

is Available for Game 1 on Sunday
A.J. Brown

Eagles Preparing for A.J. Brown's Departure?
Peter Skoronski

Titans to Pick Up Peter Skoronski's Fifth-Year Option
Breece Hall

Dynasty Upside Remains Limited by Offensive Environment in New York
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Dexter Lawrence Signing One-Year Extension With Bengals
Kristaps Porzingis

Unsure About Returning to Golden State
Drake London

Dynasty Upside Remains Limited by Quarterback Questions in Atlanta
Mark Williams

is Ruled Out for Game 1 on Sunday
Chris Olave

Dynasty Value Rising After Resurgent 2025 Season
Coby White

Hornets Want to Bring Back Coby White
Bucky Irving

Can Bucky Irving Bounce Back After Injury-Marred 2025?
Kenneth Walker III

a Major Dynasty Riser After Offseason Move to Kansas City
Desmond Bane

Considered Probable for Game 1
Bo Nix

Dynasty Value in Question Coming Off Injury?
Tarik Skubal

Fans 10 in Win Over Red Sox on Saturday
Raisel Iglesias

Dealing With Shoulder Issue
Davante Adams

Glaring Opportunity to Sell High on Davante Adams?
Jordan Addison

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Emeka Egbuka

a Trade Target in Some Dynasty Leagues
Alec Pierce

Stock Rising Following Payday
Michael Pittman Jr.

Gets a Fresh Start in Pittsburgh
Rhamondre Stevenson

an Affordable Target in Dynasty Leagues
Kyle Larson

Should not be Underestimated for the Win at Kansas
Denny Hamlin

Can Denny Hamlin Dominate at Kansas Again?
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Christoper Bell Should Contend for First Win at Kansas
Joel Eriksson Ek

Powers Minnesota Past Dallas in Opening Game
Tyler Reddick

Fastest in Practice and Qualifying for Kansas Race
Ryan Blaney

Could Score another Top-10 Finish at Kansas
Ty Gibbs

Poised to Continue Hot Streak at Kansas
Logan Stankoven

Makes Big Impact in Carolina's Game 1 Victory
Chris Buescher

Always Consistent, Has Speed Heading Into Kansas
William Byron

is A Solid DFS Option for Kansas Lineups
Carson Hocevar

Poised for Career-Best Run at Kansas
Porter Martone

Nets Game-Winning Goal to Defeat Pittsburgh
Frederik Andersen

Shuts Out Ottawa in Game 1
Chase Briscoe

Is Chase Briscoe Worth Rostering for DFS at Kansas?
Chase Elliott

Is A Favorable DFS Option for Kansas Lineups
Matt Boldy

Delivers Huge Game 1 Performance in Win
Joey Logano

Could Joey Logano be Considered Playable In DFS This Week at Kansas?
NASCAR

Bubba Wallace is A Favorable Driver to Consider for Kansas Lineups
Ross Chastain

Is Ross Chastain A Worthy DFS Option for Kansas?
Brad Keselowski

Could Brad Keselowski be A Sneaky DFS Option for Kansas?
Daniel Suarez

Should DFS Managers Roster Daniel Suarez at Kansas?
Dylan Harper

is Ready for Sunday's Game
Grayson Allen

is Questionable for Sunday's Game
Mark Williams

is Questionable for Game 1 on Sunday
Reed Sheppard

Moves into Starting Five on Saturday
Kevin Durant

is Ruled Out for Game 1 on Saturday
Stuart Skinner

Starting Game 1 Against Flyers
Alexandre Carrier

Back at Practice
Jared McCann

Undergoes Lower-Body Procedure
Andrei Kuzmenko

Activated From Injured Reserve
Victor Hedman

Out for Game 1 on Sunday
William Karlsson

Unavailable for Start of First-Round Series
Quinn Hughes

Available Saturday
Miro Heiskanen

Cleared for Game 1
Jhoan Duran

Placed on 15-Day Injured List With Oblique Strain
Kyle Stowers

Will be Activated on Sunday
Jesper Wallstedt

to Start in Goal for Minnesota on Saturday
LaMelo Ball

Scores 23 Points in Season-Ending Loss
Jordan Goodwin

Fills Stat Sheet in Play-In Win
Paolo Banchero

Powers Magic Into Playoffs
Logan Stankoven

Presumed Ready for Game 1
Max Muncy

has Another Multi-Homer Game at Coors Field
Lourdes Gurriel Jr.

Expected to Make Season Debut on Saturday
Austin Riley

Hits Two Home Runs in Shutout Win Over Phillies
Daulton Varsho

Removed Early on Friday With Knee Discomfort
Edwin Uceta

Having More Shoulder Issues, "Shut Down for a Few Days"
Josh Hader

Moved to 60-Day Injured List
Willson Contreras

Returns to Red Sox Lineup on Friday
Daniel Palencia

Goes on 15-Day Injured List With Oblique Strain
Juan Soto

Still on Track to Return Next Week
Los Angeles Angels

Garret Anderson Dies at 53 Years Old
Mike Malott

A Favorite At UFC Winnipeg
Gilbert Burns

Set For UFC Winnipeg Main Event
Kyler Phillips

Set UFC Winnipeg Co-Main Event
Charles Jourdain

Looks To Extend His Win Streak
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An Underdog At UFC Winnipeg
Mandel Nallo

Set For His UFC Debut
Karine Silva

Looks To Get Back In The Win Column
Jasmine Jasudavicius

Looks To Bounce Back
Parker Messick

Flirts With No-Hitter in Latest Gem Against Orioles
Mike Trout

Hits Five Homers in Series Versus Yankees
Spencer Arrighetti

Fans 10 in Season Debut, to Remain a Focal Point in Rotation?
Nick Pivetta

Dealing With Flexor Strain, Could Miss Months
Nico Hoerner

Homers, Drive in Five in Win Over Phillies
CFB

Michigan Lands Commitment From Quarterback Kamden Lopati
Sahith Theegala

Brings Strong Form Into Harbour Town
Wyndham Clark

Needs Putter to Show Up at RBC Heritage
Jacob Bridgeman

Looks to Return to Elite Form at Harbour Town
J.J. Spaun

a Volatile Option at RBC Heritage
PGA

Sungjae Im Offers High-Upside Value at RBC Heritage
Matt Fitzpatrick

Set for Another Strong Showing at RBC Heritage
Jason Day

Eyes Bounce-Back After Sunday Struggles at the Masters
Akshay Bhatia

Looking to Rebound at Harbour Town
Cameron Young

Hoping to Secure Second Win of Season at RBC Heritage
Scottie Scheffler

Looks to Win Again at RBC Heritage
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Has Disappointing Final Round at Masters
Viktor Hovland

Hoping to Build on Final Round at Masters
Brian Harman

Struggling For Consistency Heading to RBC Heritage
Chris Gotterup

Putting Together Outstanding 2026 Season
Justin Thomas

Looks to Defend in Hilton Head
Jordan Spieth

in Search of Improved Putting at RBC Heritage
Marco Penge

May Continue Up-and-Down Ride at the RBC Heritage
Xander Schauffele

Could Get The Job Done at RBC Heritage
Jake Knapp

Keeps Building Strong Results in 2026
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Collin Morikawa

Continues to be a Scary DFS Play at RBC Heritage
RANKINGS
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1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
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WR
TE
K
DEF