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FanDuel MLB DFS Lineup Picks (9/25/19): Daily Fantasy Baseball Advice

Joel Bartilotta highlights the top FanDuel MLB DFS lineup picks for 9/25/19, and a couple of sleepers to consider while building daily rosters.

We do have three day-games for this Wednesday slate and we’ll try to offer up a couple of plays from that slate to cater to all of you readers. It happens to be the final Wednesday article of the regular season and it’s been a treat helping you guys out all season! 

I just wanted to thank all of you for reading throughout the year, so let's finish strong!

Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @Bartilottajoel

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

FanDuel DFS Pitchers

Shane Bieber, CLE at CWS ($11,500) 

Bieber is truly one of the best pitchers in the AL. That’s evident when you see his 3.23 ERA, 1.03 WHIP, and 30.3 percent K rate, with much of that damage coming in the second half. Over his last 12 starts, Bieber is pitching to a 2.56 ERA, 1.01 WHIP, and 10.2 K/9 rate. All of those are scary numbers for an offense like this, with the White Sox ranked 24th in runs scored, 25th in K rate and 22nd in xwOBA. They’re even worse against righties, sending out hitters like Jose Abreu, Eloy Jimenez, James McCann, and Tim Anderson from the right side to oppose Bieber. All of this has the Indians entering this matchup as a –300 favorite.

Zack Greinke, HOU at SEA ($9,400) 

Greinke hasn’t quite been himself since joining the Astros but he’s still one of the best pitchers around. That’s clear when you see his 3.05 ERA and 1.01 WHIP. Those stellar numbers would put him in play against almost anyone but especially the Mariners. Not only does Seattle rank 28th in K rate, but they also sit 26th in xwOBA. Those statistics make it no surprise that this is one of the five-worst clubs in baseball since the opening month and even less surprising that Greinke enters this matchup as a –350 favorite.

 

FanDuel DFS Infielders

C.J. Cron – 1B, MIN at DET ($3,200) 

It’s amazing to see Cron’s price this low in such a good situation. The simple fact is, this dude is one of the best hitters in the Majors when he faces a lefty. That’s evident when you see his .381 OBP, .640 SLG and 1.021 OPS with the platoon advantage in his favor this season. It’s not like he has to face a tough lefty here either, with the Motor City Kitties sending out Daniel Norris and his 4.58 ERA and 1.34 WHIP. Those ugly numbers from Norris have the Twins projected for more than five runs and we anticipate Cron being a major part of that damage.

Ozzie Albies – 2B, ATL at KC ($3,700) 

This kid got a lot of crap for his team-friendly contract but he’s showing people that he means business no matter how much is on his paycheck. Over his last 21 games, Albies is hitting .387 while providing a .642 SLG and 1.069 OPS. He actually has an OPS approaching 1.000 dating all the way back to the beginning of June and it’s becoming evident that he’s one of the best second basemen in our sport. Getting to face Mike Montgomery's 5.00 ERA and 1.61 WHIP is simply the icing on the cake, with Albies generating a .390 AVG, .695 SLG and 1.103 OPS against lefties so far this year.

Alex Bregman – 3B, HOU at SEA ($4,400) 

Bregman has been the best player in baseball the last two months and it’s going to be tough to fade him in this brilliant situation. Let’s begin with this matchup, as he faces Yusei Kikuchi and his 5.55 ERA and 1.54 WHIP. That happens to give Bregman the platoon advantage, with the slugging third baseman amassing a 1.102 OPS against them this season. Not to mention, Bregman has a .373 AVG, .480 OBP, .745 SLG, and 1.225 OPS over his last 45 games played.

Jonathan Villar – SS, BAL at TOR ($3,600) 

It’s truly incredible how good Villar has been this season. He’s actually Top-5 in season-long leagues, thanks to a ridiculous second half. Over his last 55 games played, Villar has a .315 AVG, .387 OBP, .557 SLG, and .944 OPS. Those look like the numbers of an elite power hitter but he’s actually batting leadoff and has provided 21 steals in that span as well. That’s a nightmare for a guy like Jacob Waguespack, with the Toronto righty pitching to a 4.75 ERA and 1.36 WHIP.

 

FanDuel DFS Outfielders

Nelson Cruz, MIN at DET ($4,300) 

It’s crazy to see a 39-year-old mash baseballs like this guy does. It’s very reminiscent of David Ortiz near the end of his career and it’s clear Cruz has found the fountain of youth. Let’s take a look at his bonkers statistics, with Cruz being one of the league leaders with a .631 SLG and 1.018 OPS. Those are epic numbers and it doesn’t even take into consideration that he has a .402 OBP, .755 SLG and 1.156 OPS against left-handers this season. That’s terrifying news for Daniel Noris’ ugly numbers from the Cron write-up.

Tommy Pham, TB vs. NYY ($3,900) 

The Yankees are sending out J.A. Happ and that means we have to stack some Rays against him. The reason for that is because the NY southpaw is currently pitching to a 5.01 ERA and 1.30 WHIP this season. Those numbers are right up Pham’s alley, with the versatile outfielder accumulating a .467 OBP and .944 OPS against lefties so far this season.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
MarShawn Lloyd

Sees Short-Term Value Soar
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Bucky Irving

is Expected to be Ready for Training Camp
Zion Williamson

to See More Versatile Role
Parker Washington

Jaguars Think Parker Washington Can Replicate Second-Half Production
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Josh Jacobs

Arrested on Five Charges, Booked Into Jail
Claude Giroux

Planning to Return for 20th NHL Campaign
Josh Sweat

Cardinals Receiving Trade Calls on Josh Sweat
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Tetairoa McMillan

Working With the Training Staff on Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Jerome Ford

Is it Time for Dynasty Managers to Drop Jerome Ford?
John Metchie III

Poised for Breakout Season with New Team in 2026?
Jalen Milroe

Is Jalen Milroe Still Worth Stashing in Dynasty Formats Entering 2026?
Kyle Pitts Sr.

Is Kyle Pitts Sr. a Dynasty Sell-High Candidate Coming Off Breakout Season?
Nico Collins

Agrees to Contract Adjustment with Texans
Chris Brooks

Carries Buy-Low Dynasty Appeal into 2026
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
NFL

NFL Unlikely to Expand to 18 Regular-Season Games by 2027
Sahith Theegala

Searching For Swing at Charles Schwab Challenge
Lamar Jackson

in Attendance at OTAs This Week
Bucky Irving

Expected Back in the Summer or Fall
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
Jalen Tolbert

Does Jalen Tolbert Have Short-Term Dynasty Appeal?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Travis Etienne Jr.

Is Travis Etienne Jr. Still a Dynasty RB1 Following Change of Scenery?
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Ajay Mitchell

is Ruled Out for Game 5
Jalen Williams

is Tagged as Questionable for Game 5
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF