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FanDuel MLB DFS Lineup Picks (9/25/19): Daily Fantasy Baseball Advice

Joel Bartilotta highlights the top FanDuel MLB DFS lineup picks for 9/25/19, and a couple of sleepers to consider while building daily rosters.

We do have three day-games for this Wednesday slate and we’ll try to offer up a couple of plays from that slate to cater to all of you readers. It happens to be the final Wednesday article of the regular season and it’s been a treat helping you guys out all season! 

I just wanted to thank all of you for reading throughout the year, so let's finish strong!

Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @Bartilottajoel

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

FanDuel DFS Pitchers

Shane Bieber, CLE at CWS ($11,500) 

Bieber is truly one of the best pitchers in the AL. That’s evident when you see his 3.23 ERA, 1.03 WHIP, and 30.3 percent K rate, with much of that damage coming in the second half. Over his last 12 starts, Bieber is pitching to a 2.56 ERA, 1.01 WHIP, and 10.2 K/9 rate. All of those are scary numbers for an offense like this, with the White Sox ranked 24th in runs scored, 25th in K rate and 22nd in xwOBA. They’re even worse against righties, sending out hitters like Jose Abreu, Eloy Jimenez, James McCann, and Tim Anderson from the right side to oppose Bieber. All of this has the Indians entering this matchup as a –300 favorite.

Zack Greinke, HOU at SEA ($9,400) 

Greinke hasn’t quite been himself since joining the Astros but he’s still one of the best pitchers around. That’s clear when you see his 3.05 ERA and 1.01 WHIP. Those stellar numbers would put him in play against almost anyone but especially the Mariners. Not only does Seattle rank 28th in K rate, but they also sit 26th in xwOBA. Those statistics make it no surprise that this is one of the five-worst clubs in baseball since the opening month and even less surprising that Greinke enters this matchup as a –350 favorite.

 

FanDuel DFS Infielders

C.J. Cron – 1B, MIN at DET ($3,200) 

It’s amazing to see Cron’s price this low in such a good situation. The simple fact is, this dude is one of the best hitters in the Majors when he faces a lefty. That’s evident when you see his .381 OBP, .640 SLG and 1.021 OPS with the platoon advantage in his favor this season. It’s not like he has to face a tough lefty here either, with the Motor City Kitties sending out Daniel Norris and his 4.58 ERA and 1.34 WHIP. Those ugly numbers from Norris have the Twins projected for more than five runs and we anticipate Cron being a major part of that damage.

Ozzie Albies – 2B, ATL at KC ($3,700) 

This kid got a lot of crap for his team-friendly contract but he’s showing people that he means business no matter how much is on his paycheck. Over his last 21 games, Albies is hitting .387 while providing a .642 SLG and 1.069 OPS. He actually has an OPS approaching 1.000 dating all the way back to the beginning of June and it’s becoming evident that he’s one of the best second basemen in our sport. Getting to face Mike Montgomery's 5.00 ERA and 1.61 WHIP is simply the icing on the cake, with Albies generating a .390 AVG, .695 SLG and 1.103 OPS against lefties so far this year.

Alex Bregman – 3B, HOU at SEA ($4,400) 

Bregman has been the best player in baseball the last two months and it’s going to be tough to fade him in this brilliant situation. Let’s begin with this matchup, as he faces Yusei Kikuchi and his 5.55 ERA and 1.54 WHIP. That happens to give Bregman the platoon advantage, with the slugging third baseman amassing a 1.102 OPS against them this season. Not to mention, Bregman has a .373 AVG, .480 OBP, .745 SLG, and 1.225 OPS over his last 45 games played.

Jonathan Villar – SS, BAL at TOR ($3,600) 

It’s truly incredible how good Villar has been this season. He’s actually Top-5 in season-long leagues, thanks to a ridiculous second half. Over his last 55 games played, Villar has a .315 AVG, .387 OBP, .557 SLG, and .944 OPS. Those look like the numbers of an elite power hitter but he’s actually batting leadoff and has provided 21 steals in that span as well. That’s a nightmare for a guy like Jacob Waguespack, with the Toronto righty pitching to a 4.75 ERA and 1.36 WHIP.

 

FanDuel DFS Outfielders

Nelson Cruz, MIN at DET ($4,300) 

It’s crazy to see a 39-year-old mash baseballs like this guy does. It’s very reminiscent of David Ortiz near the end of his career and it’s clear Cruz has found the fountain of youth. Let’s take a look at his bonkers statistics, with Cruz being one of the league leaders with a .631 SLG and 1.018 OPS. Those are epic numbers and it doesn’t even take into consideration that he has a .402 OBP, .755 SLG and 1.156 OPS against left-handers this season. That’s terrifying news for Daniel Noris’ ugly numbers from the Cron write-up.

Tommy Pham, TB vs. NYY ($3,900) 

The Yankees are sending out J.A. Happ and that means we have to stack some Rays against him. The reason for that is because the NY southpaw is currently pitching to a 5.01 ERA and 1.30 WHIP this season. Those numbers are right up Pham’s alley, with the versatile outfielder accumulating a .467 OBP and .944 OPS against lefties so far this season.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Josh Hader

Set to Return from Injured List on Tuesday
Chris Brazzell II

a Year 1 Breakout Candidate in Carolina?
Ja'Kobi Lane

a Great Fit for Ravens, Potential Steal in Rookie Drafts
Josh Jacobs

Back at Practice on Tuesday
Max Klare

Crowded Tight End Room Impacting Max Klare's Dynasty Stock?
Romeo Doubs

Still a Solid Dynasty Option in New England?
CFB

SEC Coach Calls Buster Faulkner a "Home-Run Hire"
CFB

Auburn a Sleeper in the SEC Under Alex Golesh?
CFB

Noah Fifita Primed for Strong 2026 Campaign
CFB

Oregon Assistant Coach Charged with DUII, Reckless Driving
Makai Lemon

Set for Major Role in Debut Season?
CFB

Tight End Nick Pollack Commits to Clemson
Drake Maye

Does Latest Addition Put Drake Maye Among the Upper Echelon of Fantasy Elite?
Jalen Hurts

Could Face Regression After Loss of Top Pass Catcher
DeVonta Smith

Poised for WR1 Role in the Aftermath of Trade?
Daniel Jones

Participating in 7-on-7s
Akshay Bhatia

Needs the Driver to be True in Ohio
Aaron Rai

Primed to take on the Memorial Tournament
J.J. Spaun

Rebounded at Charles Schwab Challenge
Xander Schauffele

One to Watch This Week in Ohio
Hideki Matsuyama

Putter Could be Vital at the Memorial
Nicolai Hojgaard

Rust Concerns at Muirfield Village
Ryan Gerard

Surfaces After Long Cold Stretch with Top 10 Result
Wyndham Clark

May Struggle at the Memorial Tournament
Elly De La Cruz

to Miss 2-4 Weeks of Action
Chase Burns

is Scratched Due to Illness
A.J. Brown

Traded to Patriots in Blockbuster Deal
Deiveson Figueiredo

Suffers Second-Round Submission Loss
Song Yadong

Gets Second-Round Submission Win
Russell Wilson

Taking a Job with CBS for 2026 Season
JuJu Smith-Schuster

Giants Adding JuJu Smith-Schuster on a One-Year Deal
Zhang Mingyang

Suffers Back-To-Back Losses
Alonzo Menifield

Gets Back In The Win Column
Braxton Berrios

New York Giants Agree to One-Year Deal with Braxton Berrios
Odell Beckham Jr.

Signing with Giants
Tallison Teixeira

Suffers First-Round Knockout Loss
Myles Garrett

and Jared Verse Swap Teams in Blockbuster Deal
Sergei Pavlovich

Scores First-Round Knockout Win
Cameron Smotherman

Suffers Third Loss In A Row
Edwin Arroyo

Reds Promote Top Infield Prospect Edwin Arroyo, Viewed as Priority Pick Up Ahead of MLB Debut
Kai Asakura

Earns His First UFC Win
Elly De La Cruz

Placed on IL with Right Hamstring Tightness
Mason Taylor

Dynasty Value Takes a Hit for Now
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Zachariah Branch

a Steal in the Second Round of Rookie Drafts?
Christopher Bell

Finishes as the Runner-Up at Nashville
Chase Briscoe

Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Eli Stowers

Worth Targeting Now Before Eventual Breakout?
Kyle Larson

Top-10 Streak at Nashville Ends after Late Flat Tire Spin
Germie Bernard

Expected to Require Some Patience in Dynasty Leagues
Denzel Boston

a First-Round Target in Dynasty Rookie Drafts
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Ajay Mitchell

Ruled Out for Game 7
Jalen Williams

Unavailable in Decisive Game 7
NBA

Magic Finalizing Hire of Sean Sweeney as Head Coach
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
Jalen Williams

Limited in Game 6 Return
Jared McCain

Provides Bench Spark in Game 6 Loss
Shai Gilgeous-Alexander

Posts Lowest-Scoring Night of His MVP Season
De'Aaron Fox

Struggles From the Field Thursday
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF