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Thursday Night Football Matchups Analysis - Week 6

Thursday Night Football starts/sits and matchups analysis for Week 6 of the NFL season. Which Eagles and Giants to start or sit for fantasy football lineups.

While the New England Patriots-Indianapolis Colts rivalry wasn't as close a contest as football fans had hoped for last Thursday night, many players returned productive numbers for fantasy owners.

Tom Brady and Andrew Luck both managed to eclipse the 300-passing yard mark and throw for an identical 3:2 touchdown-to-interception ratio, allowing for multiple pass-catchers to be involved including James White (10 receptions, 77 yards, one touchdown), Rob Gronkowski (six receptions, 75 yards), and Eric Ebron (nine receptions, 110 yards, two touchdowns).

The Philadelphia Eagles currently have a 1-2 record with Carson Wentz under center while the New York Giants have struggled to take flight as an offensive unit, but that doesn't mean Week 6's Thursday Night Football game won't have some explosive plays. With plenty of startable fantasy assets ready to be slotted into your lineups, let's dive into another Thursday Night Football matchup analysis article!

Be sure to check all of our fantasy football rankings for 2025:

 

Philadelphia Eagles @ New York Giants

Date and Start Time: Thursday, October 11 at 8:00 PM ET

Notable Injuries and Status:

 

Offensive and Defensive Rankings:

Eagles Giants
Passing Yards 19th 17th
Rushing Yards 16th 28th
Pass Defense 22nd 8th
Run  Defense 2nd 27th

 

Must Starts

Top Performers That Have To Be In Your Lineup

Zach Ertz (TE, PHI)

With quarterback Carson Wentz back in the lineup, Ertz's dominance is all but guaranteed to continue as the focal point of Philadelphia's offense over the middle. The sixth-year tight end enters Week 6 with no less than five receptions in a game this season and is coming off of back to back 10-reception, 100-receiving yard performances. While the New York Giants haven't been particularly susceptible to tight ends, Ertz is sure to reverse that conception.

Saquon Barkley (RB, NYG)

Although the New York Giants rank in the bottom half of the league through the air and on the ground, Barkley managed to find ways to put up solid fantasy numbers as a rookie. Offensive coordinator Mike Shula has given Barkley no less than 16 touches per game and will undoubtedly continue to be fed against the Philadelphia Eagles so long as he is on the field. Fantasy owners shouldn't be worried about the "random back spasm" he suffered late in Week 5.

Odell Beckham Jr. (WR, NYG)

Beckham Jr. saw his most productive day of the 2018 season last week against the Carolina Panthers. Aside from his 57-yard touchdown pass to running back Saquon Barkley, he enjoyed exceptional receiving numbers that fantasy owners were hoping for in eight receptions for 131 yards and his first touchdown of the year. The Philadelphia Eagles' highly vulnerable secondary has allowed the most fantasy points per game to opposing No. 1 wideouts to open this season and should allow Beckham Jr. to continue to generate yardage.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Alshon JefferyNelson Agholor (WRs, PHI)

The New York Giants currently boast the eighth-best pass defense in the NFL, which is bad news for Jeffery and Agholor heading into Thursday night. Jeffery will have all that he can handle when taking on cornerback Janoris Jenkins, who has managed to keep DeAndre HopkinsMichael Thomas, and Devin Funchess outside of the top-30 wide receivers over the past three weeks. On the other hand, Agholor has put up 45 yards or less in four of the five games and been noticeably less involved in the passing attack with Jeffery's return.

Eli Manning (QB, NYG)

While Manning has had some success against the Philadelphia Eagles, finishing as a top-12 scoring quarterback in three of the four meetings with the Philadelphia defense under Jim Schwartz, he has only managed to throw for over 300-passing yards in one game this season and still threw two interceptions in the lone contest that he did. Fantasy owners could turn to Manning as a potential streaming option, but be wary of other quarterbacks on Sunday and Monday who could fill that role better.

Other Notable Sit CandidatesWayne Gallman (RBs, NYG), Darren Sproles (RB, PHI)

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Carson Wentz (QB, PHI)

Wentz has been progressively improving as a fantasy football quarterback since his return, finishing as the QB22, QB15, and QB8 over his three games. While the New York Giants defense has managed to limit the success of Drew Brees and Cam Newton already this season, their surprising effectiveness against the pass shouldn't be so great a deterrent to avoid starting a quarterback who is coming off of consecutive 300-passing yard, two touchdown games.

Solid Options: Corey Clement, Wendell Smallwood (RBs, PHI)

The New York Giants have been an exceptionally porous run defense, leaving the door open for Philadelphia's newly elevated lead rusher Corey Clement and spell-back Wendell Smallwood to get plenty of opportunities to break off some big runs. Head coach Doug Pederson will likely rotate the two in a committee absent Jay Ajayi and Darren Sproles, meaning enough volume will be there for both Clement and Smallwood to have solid fantasy outings.

Solid Option: Sterling Shepard (WR, NYG)

With news that tight end Evan Engram is ruled out, Shepard should be a reliable WR3 play with upside on Thursday. He has 22.4-percent of the New York Giants targets over the past three weeks and has scored a touchdown in all four meetings versus the Eagles in his career.

More Lineup Prep




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REAL-TIME FANTASY NEWS

Patrick Williams

Available Monday vs. Pelicans
Jaren Jackson Jr.

Cleared to Play Against Denver
Kevin Huerter

Ruled Out With Pelvis Soreness
Nicolas Claxton

Cleared to Face New York
Dean Wade

Sidelined Monday
Nikola Vučević

Nikola Vucevic Unavailable Against Pelicans
Landry Shamet

Sidelined Against Nets
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Making 2025 Debut on Monday
Caris LeVert

Jaden Ivey, Caris LeVert Available Versus Indiana
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Out Monday Versus Warriors
Grayson Allen

and Ryan Dunn Sidelined vs. Rockets
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Downgraded on Monday Night
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Set to Suit Up Versus Toronto
Jake Walman

to Remain Out Tuesday
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Ruled Out With Foot Sprain
Sam Merrill

and Craig Porter Jr. Out Monday
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Sidelined Versus Cleveland
Ridly Greig

Still Out Monday
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Out Versus Raptors
Baker Mayfield

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Misses Monday's Matchup
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Under the Weather, Out Versus Brooklyn
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Out Monday
Jarrett Allen

Out of Action Again on Monday
J.T. Miller

Unavailable Monday
Andrew Wiggins

Norman Powell Out on Monday Night
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Darius Garland

Sidelined on Monday
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Good to Go Monday
Chris Godwin

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Warren Schaeffer to Stick Around as Rockies Manager in 2026
Ashton Jeanty

Ankle Injury isn't Severe
Jayden Daniels

to Practice This Week, Considered a Long Shot for Week 13
C.J. Stroud

Remains in Concussion Protocol
Mike Evans

Could Return Before End of Regular Season
J.J. McCarthy

in Concussion Protocol
Tyrod Taylor

to Remain the Jets' Starting QB
Shedeur Sanders

to Make Another Start for Browns in Week 13
Tee Higgins

Won't Play on Thanksgiving
Joe Burrow

Bengals Expect Joe Burrow to Play on Thursday
Baker Mayfield

Not Being Ruled Out for Week 13
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
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Giants Fire Defensive Coordinator Shane Bowen
Tee Higgins

in the Concussion Protocol
Scott Wedgewood

Gives Avalanche Second Consecutive Shutout
Macklin Celebrini

Makes History During Multi-Point Performance
Joey Daccord

Posts Shutout in Losing Effort
David Rittich

Keeps Kraken Quiet
Jesper Wallstedt

Picks Up Third Shutout of the Season
Rasmus Andersson

Extends Point Streak With Three Assists
Davante Adams

Catches Two Touchdowns in Sunday Night Win
Baker Mayfield

has Sprained Shoulder, Will Undergo MRI Monday
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Raiders Fire Offensive Coordinator Chip Kelly
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Quinshon Judkins

Salvages his Day With Two Trips to the End Zone
Alvin Kamara

Dealing With MCL Sprain, Timetable Unclear
Michael Wilson

has Double-Digit Catches, Over 100 Yards for Second Straight Week
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

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Tagir Ulanbekov

Suffers Third-Round Submission Loss
Kyoji Horiguchi

Makes Triumphant UFC Return
MON

Alexandre Texier Joins Canadiens
Jason Dickinson

Returns to Action Sunday
Elias Lindholm

Activated From Injured Reserve
Mikko Rantanen

Suspended for One Game
Neal Pionk

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Jean-Gabriel Pageau

Out Week-to-Week
Alexander Romanov

Out 5-6 Months Due to Shoulder Surgery
Sidney Crosby

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Adolis García

Rangers Non-Tender Adolis Garcia on Friday
CFB

Beau Pribula Expected to Start Against Oklahoma
Dan Hooker

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Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
Raisel Iglesias

Returning to the Braves on One-Year Deal
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Stephan Jaeger

Looking to Bounce Back at RSM Classic
Tom Hoge

Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

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PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

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Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP