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Thursday Night Football Matchups Analysis - Week 6

Thursday Night Football starts/sits and matchups analysis for Week 6 of the NFL season. Which Eagles and Giants to start or sit for fantasy football lineups.

While the New England Patriots-Indianapolis Colts rivalry wasn't as close a contest as football fans had hoped for last Thursday night, many players returned productive numbers for fantasy owners.

Tom Brady and Andrew Luck both managed to eclipse the 300-passing yard mark and throw for an identical 3:2 touchdown-to-interception ratio, allowing for multiple pass-catchers to be involved including James White (10 receptions, 77 yards, one touchdown), Rob Gronkowski (six receptions, 75 yards), and Eric Ebron (nine receptions, 110 yards, two touchdowns).

The Philadelphia Eagles currently have a 1-2 record with Carson Wentz under center while the New York Giants have struggled to take flight as an offensive unit, but that doesn't mean Week 6's Thursday Night Football game won't have some explosive plays. With plenty of startable fantasy assets ready to be slotted into your lineups, let's dive into another Thursday Night Football matchup analysis article!

Be sure to check all of our fantasy football rankings for 2025:

 

Philadelphia Eagles @ New York Giants

Date and Start Time: Thursday, October 11 at 8:00 PM ET

Notable Injuries and Status:

 

Offensive and Defensive Rankings:

Eagles Giants
Passing Yards 19th 17th
Rushing Yards 16th 28th
Pass Defense 22nd 8th
Run  Defense 2nd 27th

 

Must Starts

Top Performers That Have To Be In Your Lineup

Zach Ertz (TE, PHI)

With quarterback Carson Wentz back in the lineup, Ertz's dominance is all but guaranteed to continue as the focal point of Philadelphia's offense over the middle. The sixth-year tight end enters Week 6 with no less than five receptions in a game this season and is coming off of back to back 10-reception, 100-receiving yard performances. While the New York Giants haven't been particularly susceptible to tight ends, Ertz is sure to reverse that conception.

Saquon Barkley (RB, NYG)

Although the New York Giants rank in the bottom half of the league through the air and on the ground, Barkley managed to find ways to put up solid fantasy numbers as a rookie. Offensive coordinator Mike Shula has given Barkley no less than 16 touches per game and will undoubtedly continue to be fed against the Philadelphia Eagles so long as he is on the field. Fantasy owners shouldn't be worried about the "random back spasm" he suffered late in Week 5.

Odell Beckham Jr. (WR, NYG)

Beckham Jr. saw his most productive day of the 2018 season last week against the Carolina Panthers. Aside from his 57-yard touchdown pass to running back Saquon Barkley, he enjoyed exceptional receiving numbers that fantasy owners were hoping for in eight receptions for 131 yards and his first touchdown of the year. The Philadelphia Eagles' highly vulnerable secondary has allowed the most fantasy points per game to opposing No. 1 wideouts to open this season and should allow Beckham Jr. to continue to generate yardage.

 

Consider Sitting

Players To Avoid Putting In Your Lineup If Possible

Alshon JefferyNelson Agholor (WRs, PHI)

The New York Giants currently boast the eighth-best pass defense in the NFL, which is bad news for Jeffery and Agholor heading into Thursday night. Jeffery will have all that he can handle when taking on cornerback Janoris Jenkins, who has managed to keep DeAndre HopkinsMichael Thomas, and Devin Funchess outside of the top-30 wide receivers over the past three weeks. On the other hand, Agholor has put up 45 yards or less in four of the five games and been noticeably less involved in the passing attack with Jeffery's return.

Eli Manning (QB, NYG)

While Manning has had some success against the Philadelphia Eagles, finishing as a top-12 scoring quarterback in three of the four meetings with the Philadelphia defense under Jim Schwartz, he has only managed to throw for over 300-passing yards in one game this season and still threw two interceptions in the lone contest that he did. Fantasy owners could turn to Manning as a potential streaming option, but be wary of other quarterbacks on Sunday and Monday who could fill that role better.

Other Notable Sit CandidatesWayne Gallman (RBs, NYG), Darren Sproles (RB, PHI)

 

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option: Carson Wentz (QB, PHI)

Wentz has been progressively improving as a fantasy football quarterback since his return, finishing as the QB22, QB15, and QB8 over his three games. While the New York Giants defense has managed to limit the success of Drew Brees and Cam Newton already this season, their surprising effectiveness against the pass shouldn't be so great a deterrent to avoid starting a quarterback who is coming off of consecutive 300-passing yard, two touchdown games.

Solid Options: Corey Clement, Wendell Smallwood (RBs, PHI)

The New York Giants have been an exceptionally porous run defense, leaving the door open for Philadelphia's newly elevated lead rusher Corey Clement and spell-back Wendell Smallwood to get plenty of opportunities to break off some big runs. Head coach Doug Pederson will likely rotate the two in a committee absent Jay Ajayi and Darren Sproles, meaning enough volume will be there for both Clement and Smallwood to have solid fantasy outings.

Solid Option: Sterling Shepard (WR, NYG)

With news that tight end Evan Engram is ruled out, Shepard should be a reliable WR3 play with upside on Thursday. He has 22.4-percent of the New York Giants targets over the past three weeks and has scored a touchdown in all four meetings versus the Eagles in his career.

More Lineup Prep




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REAL-TIME FANTASY NEWS

Brian Thomas Jr.

Tagged as Questionable for Week 11
Christian Braun

To Miss At Least Six Weeks With An Ankle Sprain
Calvin Ridley

Listed as Questionable for Week 11
Zach Edey

Questionable To Make Season Debut
Cedric Coward

Doubtful For Saturday's Game In Cleveland
John Gibson

Fine for Saturday
Kaiden Guhle

Ruled Out for 8-10 Weeks
Justin Thomas

Will Miss Start Of 2026 After Undergoing Back Surgery
Ja Morant

Off The Injury Report, Will Play Saturday
Alex Newhook

to Miss Four Months With Broken Ankle
Marco Rossi

Out Week-to-Week
J.K. Dobbins

Out in Week 11 and for "Foreseeable Future"
Zach Hyman

Set for Season Debut Saturday
Jack Hughes

Sustains Non-Hockey Hand Injury
Quinn Hughes

a Game-Time Decision Friday
Jaden Ivey

Participates in Pistons Morning Shootaround on Friday
Rashod Bateman

Ruled Out for Week 11
Sam LaPorta

Ruled Out for Week 11 With Back Injury
Coby White

Nearing A Return?
Isiah Pacheco

Officially Ruled Out for Week 11
Josh Giddey

Fully Practices On Friday
Day'Ron Sharpe

Available to Play on Friday
Trey Hendrickson

Shemar Stewart Both Out for Week 11
Julian Champagnie

Questionable For Rematch Against Warriors
Jaxson Dart

Officially Ruled Out for Week 11 Due to Concussion
Jonathan Kuminga

Sitting Out Friday's NBA Cup Game
Darius Slayton

Ruled Out for Sunday
Dereck Lively II

Expected To Return To Action Friday
Davante Adams

Questionable for Sunday but Expected to Play
Drake London

Questionable vs Panthers
Islam Makhachev

Set For UFC 322 Main Event
Jack Della Maddalena

Set For His First Title Defense
Zhang Weili

Can Become The New Women's Flyweight Champion
Valentina Shevchenko

Set For UFC 322 Co-Main Event
Garrett Wilson

Jets Expect Garrett Wilson to Play Again This Season
Michael Morales

Looks To Remain Undefeated
Lamar Jackson

Ready to Roll for Sunday
CFB

Mario Craver a Game-Time Decision for Week 12
Sean Brady

Set For Title Eliminator Bout
Quentin Johnston

Questionable to Play Against Jaguars
Carlos Prates

A Favorite At UFC 322
Jaxson Dart

"on Track" in the Concussion Protocol
Leon Edwards

Looks To Get Back In The Win Column
Benoît Saint Denis

Benoit Saint Denis Set To Open Up UFC 322 Main Card
Beneil Dariush

Looks To Win Back-To-Back Fights
Chris Godwin

Missing Another Game
Bucky Irving

Officially Ruled Out for Week 11
Darius Slayton

Expected to Miss Week 11
Khalil Shakir

"Heading in the Right Direction" for Week 11
Chris Godwin

Practices Again, Status Uncertain for Week 11
Bucky Irving

Practices Again to Close Out the Week
Kawhi Leonard

Out on Friday vs. Mavs
Lauri Markkanen

Drops 40 Points Against Hawks
Onyeka Okongwu

Posts Double-Double in Win Over Jazz
Jalen Johnson

Produces Huge Triple-Double
Kel'el Ware

Ready to Suit Up on Friday
Norman Powell

Listed as Available Against Knicks
Davion Mitchell

Good to Go Friday Vs. Knicks
Jaime Jaquez Jr.

Available for Friday's Matchup with Knicks
Terrence Shannon Jr.

Ruled Out Friday vs. Kings
CFB

Virginia's Chandler Morris Trending Toward Facing Duke on Saturday
LeBron James

Out on Friday
Shane Pinto

Lands Four-Year Extension
Thomas Chabot

to Sit Out Two Weeks
William Karlsson

Out Week-to-Week
Alex Newhook

Injured in Big Loss
Jeff Skinner

Hurt Early on Thursday
John Gibson

Exits With Upper-Body Injury Thursday
Kaapo Kakko

Sustains Lower-Body Injury Thursday
Edwin Díaz

Edwin Diaz Says There's a "50-50" Chance he Returns to Mets
Shohei Ohtani

Wins his Fourth MVP Award
Aaron Judge

Wins AL MVP Award Again
Dylan Samberg

Makes Season Debut Thursday
Samuel Girard

Available Thursday
Valeri Nichushkin

Considered Week-to-Week
Boone Jenner

Out Long-Term With Upper-Body Injury
Mikael Granlund

Returns to Action Thursday
Anthony Stolarz

Out Day-to-Day
Auston Matthews

Likely to Miss One Week
Raisel Iglesias

Dodgers Interested in Signing Raisel Iglesias
Pete Alonso

Orioles Could be in the Mix to Sign Pete Alonso
Félix Bautista

Felix Bautista Could Return in Second Half in 2026
Kodai Senga

Attracting Trade Interest, Will the Mets Move him?
Yordan Alvarez

Expected to be Ready for Spring Training
Byron Buxton

Could Waive his No-Trade Clause
Paul Skenes

the Unanimous NL Cy Young Winner
Tarik Skubal

Wins AL Cy Young for Second Straight Year
CFB

Still No Update on Jermod McCoy's Return Timeline
Sami Valimaki

Riding Momentum Into Bermuda
Matthieu Pavon

Struggling Through a Rough Season
Taylor Montgomery

Hopes to Get Back on Track at Port Royal
Ben Martin

a Risky Play at Bermuda Championship
Mark Hubbard

Primed for a Bounce-Back Week in Bermuda
Lee Hodges

Searching for a Spark in Bermuda
Stephen Vogt

Wins Back-to-Back AL Manager of the Year Honors
Milwaukee Brewers

Pat Murphy Named NL Manager of the Year Again
Patrick Fishburn

Looking to Bounce Back in Bermuda
Eric Cole

Carrying Momentum into Bermuda
Tommy Edman

to Have Ankle Surgery Next Week
Ketel Marte

Diamondbacks Unlikely to Trade Ketel Marte
Roman Anthony

to Have a Normal Offseason
Jarren Duran

Red Sox Think Jarren Duran Needs a Fresh Start
MacKenzie Gore

Nationals Expected to Trade MacKenzie Gore?
Sahith Theegala

Finishes Tied for 27th at Bank of Utah Championship
Sam Stevens

Finishes Tied for 36th at Baycurrent Classic
Patrick Rodgers

Finishes Tied For Sixth at World Wide Technology Championship
Luke List

Finishes 75th at World Wide Technology Championship
Ben Kohles

Finishes Tied for 63rd at World Wide Technology Championship
PGA

Nico Echavarria Finishes Tied for 14th at World Wide Technology Championship
Luke Clanton

Finishes Tied for 46th at World Wide Technology Championship
Blades Brown

Finishes Tied for 18th at Korn Ferry Tour Championship
Tarik Skubal

Tigers Unlikely to Trade Tarik Skubal
Framber Valdez

Cubs Could Land Framber Valdez in Free Agency
Sandy Alcantara

Marlins Ready to Trade Sandy Alcantara
CFB

Nic Anderson Could Return for LSU this Season
Randy Brown

Suffers Second-Round TKO Loss
Gabriel Bonfim

Extends His Win Streak
Joseph Morales

Gets First-Round Submission Win
Matt Schnell

Suffers First-Round Submission Loss
Muslim Salikhov

Suffers First-Round TKO Loss
Uros Medic

Wins Back-To-Back Fights
Ismael Bonfim

Loses Back-to-Back Fights
Chris Padilla

Remains Unbeaten In The UFC
Marco Tulio

Suffers His First UFC Loss
Christian Leroy Duncan

Scores Second-Round Knockout Victory

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP