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Key Starters and Tough Calls - Lineup Spotlights for Week 17

Scott Engel breaks down his Week 17 fantasy football lineup rankings, spotlighting key NFL players to start and tougher lineup start/sit decisions to make.

Welcome to Week 17, RotoBallers! Below you will find some of my spotlight plays and tough lineup decisions for the upcoming week of the fantasy football playoffs.

It is with mixed feelings that I greet you this week, as I am glad you made it to your league Super Bowl. But I also honestly angry at your commissioner for putting you in a bigger spot of uncertainty to decide the title. No legitimate Fantasy championship game should be held in Week 17.

These player selections are based on my Premium Weekly Lineup Rankings, available as part of the RotoBaller's NFL Premium Pass. Note that all skill position picks and analyses here are based on my PPR ranks.

Be sure to check all of our fantasy football rankings for 2025:

 

Spotlight RB Starters for Week 17

Miles Sanders vs. NYG: He may cede a few touches to Boston Scott and the returning Jordan Howard. But Sanders will still be the Eagles’ lead RB as they try to clinch the NFC Least. You must lean toward using players that are competing in games of true significance this week.

Raheem Mostert vs. SEA: If the 49ers win this game, you can bet Mostert will be a key contributor. He has clearly emerged as San Francisco’s best RB and is a danger to the defense no matter where and how he gets the ball. The Seahawks are vulnerable to large chunk gains by opposing RBs.

Deandre Washington vs. DEN: He is a must-start as the Raiders try to keep their long-shot playoff hopes alive. Josh Jacobs is out again and Washington has already shown he can be an adequate fill-in.

 

Spotlight WR Starters for Week 17

A.J. Brown vs. HOU: The Texans may not play for anything by the time their game starts, and the Titans simply must win this game. Brown is the clear WR1 for the Titans, and Bradley Roby’s hamstring problem can only boost the outlook of the Tennessee passing game.

Amari Cooper vs. WAS: He has been completely unreliable and it’s hard to start him with any level of comfort right now. But the Washington secondary has been completely decimated and this just too good of a draw for Cooper and Michael Gallup.

Tyler Lockett vs. SF: No WR has been a bigger fantasy disappointment in the second half of the season than Lockett, who flamed out again in Week 16. But the Seahawks staff and Russell Wilson are going to devise many ways to get him the ball in the most important game of the week.

 

Spotlight QB Starters for Week 17

Ryan Tannehill vs. HOU: The No. 1 QB start of Week 17. He has been dependable for quality performances and has been outstanding at times, and he is in a must-win situation against a team that may not come to play at all.

Jimmy Garoppolo vs. SEA: This is the biggest game of Garoppolo’s career so far, and he is playing better than he did the last time these teams met. He has the opportunity to come through in the most important spot of his life and won’t disappoint.

 

Spotlight TE Starters for Week 17

Jonnu Smith vs. HOU: He has arrived as a top fantasy starter at his position just in time for your final game. If you are playing in a championship game this week, starting choices are very dicey, and you should go with a player like this, who has momentum, playoff incentive, and faces an opponent that can be easily taken advantage of.

Jacob Hollister vs. SF: Players in the passing game on both sides of the ball should get strong starting consideration this week. Hollister may be the Seahawks’ best possession receiver right now.

 

Tough Week 17 Lineup Decisions

Travis Homer over Marlon Mack: Despite all the Marshawn Lynch hoopla, Homer may be Seattle’s best RB for fantasy purposes this week. Mack could see his workload reduced in a meaningless game.

Latavius Murray over Marshawn Lynch: Murray may not start, and Lynch likely will, but we already are more certain of the playing shape Murray is in. Even with Alvin Kamara suddenly looking rejuvenated, Murray can rip off a big gain or score even with a limited workload.

D.K. Metcalf over Breshad Perriman: The Tampa Bay WR should finish the season with another quality outing as he heads into free agency. But Metcalf is playing in a game of far greater significance, and the Seahawks have to put increased emphasis on getting him into the offensive flow again.

Greg Ward over Courtland Sutton: Again, it comes down to who is competing in the more important game here. Ward is going to play a very large role in the depleted Philadelphia passing game, and he has a very good matchup vs. the Giants.

O.J. Howard over Mike Gesicki: Howard really needs to finish well after a disappointing year. Gesicki gets a very daunting matchup against a Patriots team with a formidable defense, looking to hammer down a first-round bye.

Matt Ryan over Patrick Mahomes: The Falcons have played well recently, and will not lay down after Arthur Blank confirmed his satisfaction by announcing Dan Quinn and Thomas Dimitroff will be back next season. Mahomes may not play a full game if the Patriots jump out to a big lead quickly on the Dolphins and any chance at the No. 2 seed in the AFC has apparently vanished.

More Weekly Lineup Prep




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REAL-TIME FANTASY NEWS

MON

Samuel Montembeault Ruled Out for Sunday
Carter Hart

Available Against Rangers Sunday
Ryan Leonard

to Miss "Extended Period of Time"
De'Von Achane

Avoids a Broken Rib in Week 14
John Carlson

a Game-Time Decision Sunday
Zach Ertz

Feared to Have Torn ACL
Jordan Kyrou

Unavailable Against Canadiens
Daniel Jones

Could be Done for Season with Achilles Injury
Matt Duchene

Set to Return Against Penguins
Jayden Daniels

Will Play Again This Season
Pyotr Kochetkov

Back for Hurricanes Sunday
Evgeni Malkin

Won't Play on Sunday
CFB

Notre Dame Opting Out of Postseason Amid College Football Playoff Exclusion
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Ruled Out Sunday With Serious Knee Injury
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Ruled Out Against Orlando
Draymond Green

Remains on the Shelf Versus Chicago
Jimmy Butler III

Expected to Return on Sunday
Jayden Daniels

Questionable to Return in Week 14 With Left-Elbow Injury
Immanuel Quickley

Now Probable Versus Boston
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Returns in Week 14 After Injury Scare
Shai Gilgeous-Alexander

Will Miss First Game of the Year on Sunday
De'Von Achane

Questionable to Return in Week 14 with Rib Injury
Joel Embiid

Upgraded to Probable Against Lakers
Bhayshul Tuten

Being Evaluated For Concussion
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Ruled Out After Non-Contact Achilles Injury
Ja Morant

Doubtful Against Portland
Robert Williams III

Now Questionable Versus Memphis
Donovan Clingan

Questionable Versus Grizzlies
Pittsburgh Steelers

Steelers Won't Fire Mike Tomlin This Year
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Officially Active in Week 14
Dalton Kincaid

Suiting Up Against Bengals
CFB

Kendal Briles a Candidate for South Carolina Offensive Coordinator Job
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James Madison Playoff-Bound After Duke Wins ACC Title?
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Notre Dame, Miami, Alabama on College Football Playoff Bubble
Garrett Wilson

Still Expected to Return and Contribute in 2025
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Brent Pry Could Return to Virginia Tech as Defensive Coordinator
Mike Evans

Could Return in Week 15
Trey Benson

Might Not Return This Season
Darcy Kuemper

Ends Losing Streak With Shutout Performance
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Collects Three Points in Saturday's Win
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Ties Franchise Record With 25th Shutout
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Bags Season-High Four Points Saturday
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Sustains Lower-Body Injury Saturday
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Hurt on Saturday
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Trending Toward Playing Against Broncos
Chris Olave

Set to Play Vs. Bucs
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Won't Suit Up Against Denver
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Questionable for Sunday Afternoon
Deshaun Watson

Expected to Stay With Browns Next Year
Klay Thompson

Downgraded Versus Houston
Alperen Sengün

Alperen Sengun Out Again on Saturday Evening
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Will Miss Another Game on Saturday
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Out Again on Saturday Night
Draymond Green

Ruled Out Versus Cleveland
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Mason Marchment

Expected to Return Saturday
Danila Yurov

Returns From Two-Game Absence Saturday
Jesperi Kotkaniemi

Available Saturday
Harry Ford

Traded to the Nationals
Shane Pinto

to Miss Two Weeks
David Pastrnak

Misses Fifth Consecutive Game Saturday
Andrei Vasilevskiy

Remains Out Saturday
Nikita Kucherov

Out on Saturday
Jayden Reed

Activated Off Injured Reserve, Will Play in Week 14
Omarion Hampton

Activated From IR, Faces Uncertain Workload Monday Night
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Yves Missi

Trending Toward Game-Time Decision
Khris Middleton

Questionable With Knee Soreness Against Hawks
Noah Clowney

On Track To Suit Up Against Pelicans
De'Anthony Melton

Questionable With Knee Management
Draymond Green

Questionable With Mid-Foot Sprain
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
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Looks To Reclaim Bantamweight Belt
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Set For His Fourth Title Defense
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Can Become The New Flyweight Champion
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Set For Fifth Title Defense At UFC 323
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Looks To Win Back-To-Back Fights
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Searches For His Third Win In A Row
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Henry Cejudo

Set For His Retirement Fight
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Set To Open Up UFC 323 Main Card
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
CFB

Jam Miller Unlikely to Play in SEC Title Game
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Penn State Expected to Hire Matt Campbell from Iowa State
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
CFB

Lane Kiffin Working to Keep Defensive Coordinator Blake Baker at LSU
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Brian Daboll a Candidate for Penn State Head-Coaching Job?
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
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Brent Key Signing Five-Year Deal to Remain at Georgia Tech
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Brian Hartline Expected to Land USF Head-Coaching Job
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Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
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Chris Klieman Considering Stepping Down at Kansas State
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D.J. Durkin Staying at Auburn Under Alex Golesh
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Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
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Willson Contreras

Willing to Waive his Full No-Trade Clause?
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?

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