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DraftKings MMA, UFC DFS Lineup Picks - UFC Vegas 110: Garcia vs. Onama on 11/1/25. Alen's MMA DFS analysis to build winning daily fantasy UFC lineups.
Last week's UFC 321 was supposed to be a great card; however, it turned out to be extremely disappointing, especially the main card and the main event between Tom Aspinall and Ciryl Gane. But now, we're back at the Apex for UFC Vegas 110 fight card, which on paper doesn't look that good because it has no star power, but in actuality, it has some intriguing and exciting fights like the main event between surging featherweights Steve Garcia and David Onana, and the co-main event between former PFL champion Ante Delija and Waldo Cortes-Acosta.
To open up the UFC Vegas 110 main card, we have flyweights Allan Nascimento and Cody Durden, followed by a welterweight bout between Charles Radtke and Daniel Frunza. Also on the main card, featherweights Isaac Dulgarian and Yadier del Valle are scheduled for a three-round scrap, followed by a welterweight fight between Themba Gorimbo and Jeremiah Wells.
In this article, I will be providing you with my fantasy MMA lineup picks for UFC Vegas 110: Garcia vs. Onama on 11/1/25. Give me a follow on X @sumpor5. Good luck!
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DraftKings MMA Featherweight - UFC DFS Lineup Picks
David Onama, $7.9K - vs. Steve Garcia
Surging featherweights David Onama and Steve Garcia are scheduled to headline the UFC Vegas 110 event on Saturday. Both Onama and Garcia are looking to extend their win streak.
A true joy to watch in the Octagon 😮💨
Don't miss @DavidOnama145 in the #UFCVegas110 main event!
[ NOV 1 | 7pmET on the @ESPN app ] pic.twitter.com/dJ4DZzvkd5
— UFC (@ufc) October 28, 2025
Onama arrives at UFC Apex as a slight underdog. The 31-year-old Onama is a high-pressure fighter and striker who pushes the pace, capable of breaking down less durable opponents. He is currently on a four-fight winning streak, which includes three decisions, with two of them scored 29-28 in his favor, but all unanimously his way.
Onama was last seen in action in April at UFC Kansas City, where he extended his win streak by beating Giga Chikadze via unanimous decision. Before that, Onama outpointed Roberto Romero and Jonathan Pearce, and finished Gabriel Santos by second-round knockout. The last time he suffered a loss was to Nate Landwehr back in 2022 at UFC San Diego.
Garcia didn't have the best start to his UFC career as he went 1-2 in his first three fights, but since then, it's safe to say that he's on a tear, winning six fights in a row. Out of those six fights, five of them ended in a knockout/TKO victory, lifting him into the top 15 of the division. Known as a knockout artist, Garcia has finished 14 out of his 18 fights via knockout/TKO.
He was last seen in action in July at UFC Nashville, where he defeated Calvin Kattar via unanimous decision. He may not have been able to knock Kattar out, but he dominated him from the start of the fight to the finish.
Onama enters this fight with an MMA record of 14-2 and 6-2 in the UFC. He is averaging 5.24 significant strikes per minute and has a striking accuracy of 50%. Onama is absorbing 4.73 strikes per minute and has a striking defense of 52%. His grappling has been decent, averaging 1.08 takedowns every 15 minutes. Further, he has a takedown accuracy of 30% and a takedown defense of 52%.
Garcia comes into this fight with an MMA record of 18-5 and 7-2 in the UFC. He is averaging 5.18 significant strikes per minute and has a striking accuracy of 48%. Garcia is absorbing 2.20 strikes per minute and has a striking defense of 57%. Regarding his grappling, Garcia is averaging 0.90 takedowns every 15 minutes. His takedown accuracy is 40% and his takedown defense is 88%.
I'm not going to lie, this fight can go either way, but there's one thing that is guaranteed, and that is violence. Both fighters like to pressure their opponents, and both prefer the fight to remain on the feet. Garcia has a more impressive win, but I'm leaning a little bit towards Onama because of his explosiveness.
Both Garcia and Onana have solid cardio and can go five rounds, but I don't think this fight will go the distance. My prediction is that Onama will knock Garcia out within three rounds.
DraftKings MMA Heavyweight - UFC DFS Lineup Picks
Ante Delija, $8.0K - vs. Waldo Cortes-Acosta
Heavyweights Ante Delija and Waldo Cortes-Acosta are scheduled for a three-round co-main event of UFC Vegas 110 on Saturday. Delija aims for his second win in the UFC while Cortes-Acosta looks to get back in the win column.
DOMINANT in his debut 😤
Ante Delija looks to deliver another impressive performance in the co-main event at #UFCVegas110!
[ NOV 1 | 7pmET on the @ESPN app ] pic.twitter.com/Qd73bSy3BZ
— UFC (@ufc) October 30, 2025
Delija made his UFC debut in September at UFC Paris and didn’t take long to knock out Marcin Tybura, 123 seconds to be exact, and he's already set to make a quick turnaround against Cortes-Acosta. The 35-year-old Croatian managed to exact his revenge on Tybura, who defeated Delija after he sustained a broken leg, which resulted in him missing almost three years.
Known for his speed, striking, and knockout power, Delija has finished 19 of his opponents, 12 via knockout/TKO and nine via submission. Even though he only fought once in the UFC, Delija is, without a doubt, at this point, one of the more interesting fighters in the UFC’s heavyweight division.
Cortes-Acosta started his career 9-0 before falling to Marcos Rogerio de Lima in 2023. He got back in the win column in his next fight by defeating Lukasz Brzeski via first-round knockout. He went on a five-fight win streak, which included wins over former heavyweight champion Andrei Arlovski, Ryan Spann, and Serghei Spivac.
However, his five-fight win streak was snapped last time out after he lost a lacklustre unanimous decision to Sergei Pavlovich. Known for his boxing, Cortes-Acosta is one of the few heavyweights who has an effective jab and calf kicks.
Delija enters this fight with an MMA record of 26-6 and 1-0 in the UFC. He averages 6.34 significant strikes per minute and has a striking accuracy of 46%. Delija absorbs 1.95 strikes and has a striking defense of 55%.
Cortes-Acosta enters this fight with an MMA record of 14-2 and 8-2 in the UFC. He averages 5.61 significant strikes per minute and has a striking accuracy of 48%. Cortes-Acosta absorbs 3.51 strikes and has a striking defense of 55%. His grappling is decent at best, averaging 0.37 takedowns every 15 minutes. He has a takedown accuracy of 50% and a takedown defense of 71%.
Although Cortes-Acosta has looked good thus far, I just think Delija is on another level. The former PFL champion also trains regularly with heavyweight champion Tom Aspinall and has gone 14-3 since breaking his leg, and is 9-1 since 2022. Delija will be too fast for Cortes-Acosta, and my prediction is that Delija will knock Cortes-Acosta out in the first or the second round.
DraftKings MMA Welterweight - UFC DFS Lineup Picks
Themba Gorimbo, $8.4K - vs. Jeremiah Wells
Themba Gorimbo is set to face off against Jeremiah Wells on the main card of UFC Vegas 110 on Saturday. Both Gorimbo and Wells are looking to get back in the win column.
He only needs one to land 👊
Themba Gorimbo is ready to get his next finish this weekend!
[ #UFCVegas110 | SAT NOV 1 | 7pmET on the @ESPN app ] pic.twitter.com/rFql2E4gBp
— UFC (@ufc) October 29, 2025
After an unsuccessful UFC debut where he suffered a second-round submission loss to AJ Fletcher, Gorimbo went on a four-fight winning streak, beating Takashi Sato, Pete Rodriguez, Ramiz Brahimaj, and Nico Price. His only recent setback came in December at UFC 310 at the hands of veteran Vicente Luque, who submitted him in under a minute.
He usually starts his fight keeping his opponents at range, but he has no problem trading in the pocket, using knees, elbows, and uppercuts. While it's hard to know whose wrestling is better, Gorimbo should also have a striking advantage over Wells with his slight height and reach advantage.
Both Wells and Gorimbo have solid wrestling, although their approach to taking their opponents down differs. Wells is extremely explosive, and he usually goes for clinch lifts and power doubles, and is always looking to close the distance. He’s most dangerous early, particularly in the first round, where his power and athleticism can overwhelm opponents.
He is currently on a two-fight losing skid, having suffered a submission loss to Carlston Harris and, more recently, dropping a split decision to Max Griffin.
Gorimbo enters this fight with an MMA record of 14-5 and 4-2 in the UFC. He averages 3.15 significant strikes per minute and has a striking accuracy of 61%. Gorimbo absorbs 1.09 strikes per minute and has a striking defense of 56%. He also has elite grappling, averaging 4.81 takedowns every 15 minutes. Gorimbo has a takedown accuracy of 65% and a takedown defense of 82%.
Wells enters this fight with an MMA record of 12-4-1 and 4-2 in the UFC. He averages 2.41 significant strikes per minute and has a striking accuracy of 43%. Wells absorbs 1.31 strikes per minute and has a striking defense of 48%. His grappling has been elite, averaging 3.08 takedowns every 15 minutes. He has a takedown defense of 44% and a takedown defense of 80%.
The best chance for Wells to win this fight is within five minutes, where he could use his explosiveness to close the distance, exchange in the pocket. He could also potentially take Gorimbo down and get top control, but if Gorimbo manages to survive the first round, his smothering wrestling, striking, and cardio will prevail.
I don't think Gorimbo will be able to finish Wells, but he's durable enough, and if he remains composed, he should be able to win by unanimous decision.
