FanDuel NFL DFS Lineup Picks for Week 15 - Daily Fantasy Football

December 19, 2021

Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 15 of the 2021 season, and some value sleepers for your daily fantasy football rosters.

Without question, things are certainly a mess around the National Football League. In previous years, periodic injuries made things difficult. However, with COVID-19 still prevalent, things are even more challenging, even more so with an added game to each team's schedule.

Undoubtedly, the number of absences heading into Sunday is troubling for fantasy managers, especially those currently battling for a championship in seasonal formats. Yet, from a DFS standpoint, the number of value opportunities available in Week 15 is the most in recent memory.

In this article, I will be providing you with my Week 15 daily fantasy football lineup picks for FanDuel. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Also, feel free to give me a follow on Twitter @DennisMClausen.

FanDuel Quarterbacks - Week 15 DFS Lineup Picks

Kyler Murray, QB - @ DET ($8,800)

Murray had a rough showing during the Monday Night Football loss to the Los Angeles Rams in Week 14. Fortunately, he has a good chance of turning things around against Detroit, a team that hasn't been impressive by any means. No, the signal-caller won't have DeAndre Hopkins, who will miss--at least--the remainder of the regular season because of a knee injury. James Conner is also questionable due to an ankle issue, so he will likely be limited even if he suits up. However, Murray still has some fantastic options on the offensive end, and he is more than capable of making some big plays on his own, especially on the run.

Dak Prescott, QB - @ NYG ($7,500)

Prescott will probably be a popular addition in DFS lineups in Week 15. He hasn't played the best, though, which is why his significantly reduced rostering cost is $1,300 less than Kyler Murray's. Yet, he has played great against the Giants during his career, and his most recent outing against the G-Men resulted in a 21.68-point fantasy day. New York has also been having issues on the defensive end, so Dak's upside is higher than most on Sunday.

Also Consider: Josh Allen ($8,700), Aaron Rodgers ($7,600), Jimmy Garoppolo ($6,700)

FanDuel Running Backs - Week 15 DFS Lineup Picks

Joe Mixon, RB - @ DEN ($8,300)

Mixon had a nine-game streak with at least one touchdown entering Week 14 against the 49ers. However, that streak was snapped, with the former Oklahoma Sooner finished with a disappointing 58 yards off 18 carries. The Bengals and Broncos will battle to remain in the postseason conversation, and if Cincinnati wants to get back on track, it will have to rely on Mixon for that to happen.

Ezekiel Elliott, RB - @ NYG ($6,700)

Elliott has been one of the biggest fantasy disappointments this season. Tony Pollard didn't play in Week 14 against Washington, so naturally, it was assumed Zeke would get an even more prominent workload combined with a much higher ceiling. Yet, that didn't happen, as he would finish with an atrocious 8.5 fantasy points. However, Elliott has historically done some damage against the Giants over the years, nearly averaging a touchdown a game versus New York during his career.

Also Consider: Cordarrelle Patterson ($7,000), Javonte Williams ($7,000), James Robinson ($6,300), Devonta Freeman ($5,900), Jeff Wilson Jr. ($5,800)

FanDuel Wide Receivers - Week 15 DFS Lineup Picks

Deebo Samuel, WR - vs. ATL ($8,200)

Samuel suffered a groin injury against the Vikings a few weeks ago and only missed one game as a result. He made it back sooner than initially anticipated and was in the lineup against the Bengals, finishing with only one catch. However, Samuel did have eight carries for 37 yards and a touchdown, and with Elijah Mitchell out in Week 15, the speedy wideout should continue to get plenty of opportunities to put up some numbers.

A.J. Green, WR - @ DET ($5,700)

Without DeAndre Hopkins, some targets will be up for grabs against Detroit, with the potential for more if Zach Ertz doesn't play. Christian Kirk is a favorite to benefit, but so could Green, who has played better than projected during the 2021-22 campaign. The 33-year-old caught seven of his 10 targets against the Rams in Week 14, and though the Cards were playing from behind, there's no reason to believe he won't remain an essential piece of the offense while remaining capable of exceeding his value versus the Lions.

Also Consider: Davante Adams ($8,500), Stefon Diggs ($7,800), CeeDee Lamb, ($7,400), Diontae Johnson ($7,200), Gabriel Davis ($4,900),

FanDuel Tight Ends - Week 15 DFS Lineup Picks

Dawson Knox, TE - vs. CAR ($6,500)

Knox has played well this season. He caught seven of his nine targets for 60 yards and a touchdown during the team's most recent outing against the Buccaneers to bring his total to eight trips to the end zone. Emmanuel Sanders is doubtful after he injured his knee in Week 14. As a result, Knox should continue to get some attention from Josh Allen, who may have to throw more than usual after dealing with a foot ailment during the week.

Also Consider: George Kittle ($7,800), Dalton Schultz ($5,600), Zach Ertz ($5,300)

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