November 8, 2025
San Francisco 49ers wide receiver
Demarcus Robinson will be granted at least one more week as the team's third wide receiver while
Ricky Pearsall (knee) sits out a fifth consecutive game. Working behind
Christian McCaffrey,
Jauan Jennings (ankle, shoulder),
George Kittle, and
Kendrick Bourne in the pass game will leave few opportunities for Robinson. In Week 5, when the 49ers and Rams met for the first time in 2025, Robinson was held to three catches for 39 yards, even though Jennings, Pearsall, and Kittle were all absent due to injury. Since Jennings and Kittle rejoined the starting lineup in Week 7, Robinson has seen a total of five targets and was held without a catch in two of San Francisco's three games. In Week 10, Robinson should not be on fantasy football rosters, let alone starting lineups.
--Dan StephensSource: NFL.com
November 8, 2025
San Francisco 49ers wide receiver
Kendrick Bourne is in line for another start on Sunday when the team hosts the Los Angeles Rams. The last time the divisional rivals squared off, in Week 5, Bourne exploded for 142 yards on 10 catches. Bourne was pushed to the top of the pecking order in the Niners' passing attack in that game due to the injury-related absences of
Ricky Pearsall (knee),
Jauan Jennings (ankle, shoulder), and
George Kittle. Pearsall will miss a fifth consecutive game in Week 10, but Bourne will share the field with a healthy Jennings and Kittle this time. Since both returned to action in Week 7, Bourne has registered a total of seven catches for 92 yards on eight targets. Bourne projects as a lower-end WR4 in Week 10, making him a flex candidate in deeper leagues but not a must-start by any stretch.
--Dan StephensSource: NFL.com
November 8, 2025
San Francisco 49ers wide receiver
Jauan Jennings (ankle, shoulder) carries no designation into the team's Week 10 rematch with the Los Angeles Rams. Jennings, along with
Ricky Pearsall (knee) and
George Kittle, missed the teams' first matchup in Week 5 due to injuries, leading to a ten-catch, 142-yard bonanza for
Kendrick Bourne. Jennings himself torched Los Angeles to the tune of 11-175-3 in Week 3 last season. Since returning from his absence, Jennings has not been very productive, though he still has been a focal point of the 49ers' offense. Over the last three weeks, he had a 24.7% target share and 34.6% air yard share. The Rams will likely have their attention focused on
Christian McCaffrey on Sunday, which could open things up for Jennings to take another step forward. He projects as a WR3 and can be started in most leagues in Week 10.
--Dan StephensSource: NFL.com
November 8, 2025
San Francisco 49ers running back
Brian Robinson Jr. had a season-high 53 rushing yards and his first touchdown of the season in Week 9 against the Giants. The production gave him his first RB2 finish of 2025. Robinson is unlikely to repeat last week's success when the 49ers host the Rams on Sunday. For one, the opportunity for Robinson to produce consistently is not there. Operating as an infrequently used change-of-pace back behind
Christian McCaffrey has resulted in an average of 10 offensive snaps and 4.6 rushing attempts per game. Secondly, when Robinson does get on the field in Week 10, he will be up against a Rams defense that held him to 12 yards on five carries and offered McCaffrey 2.6 yards per carry in Week 5. Robinson projects as an RB5 and is better left on the bench in Week 10.
--Dan StephensSource: NFL.com
November 8, 2025
San Francisco 49ers running back
Christian McCaffrey took a while to get things going on the ground, but now has reached 100 rushing yards in two of his last three games. However, in the game between, McCaffrey put up his worst numbers of the year in a slog against the Houston Texans. On Sunday, McCaffrey again faces another tough opponent in the Los Angeles Rams. The Rams have allowed the fewest fantasy points per game to opposing running backs, the sixth-fewest rushing yards, and have yet to give up a touchdown on the ground to the position. When the teams met in Week 5, McCaffrey had just 2.6 yards per carry but logged an 8-82-1 line as a receiver. Despite the difficult matchup, McCaffrey's talent makes him a weekly contender to finish as a top-12 back, and he should be locked into fantasy lineups this weekend.
--Dan StephensSource: NFL.com
November 8, 2025
San Francisco 49ers quarterback
Mac Jones (knee) is expected to draw his eighth start of the season in Week 10 against the Los Angeles Rams.
Brock Purdy (toe) is listed as questionable after a week of limited practices, and would serve as Jones' backup if active. The last time Jones faced the Rams, he enjoyed his best game of the season, passing for 342 yards and two touchdowns with no turnovers, and did so with
Ricky Pearsall (knee),
Jauan Jennings (ankle, shoulder), and
George Kittle out due to injury. It was an exceptional lapse for the Rams' defense, which has given up just nine passing touchdowns and has allowed only one other top-12 finish to an opposing quarterback this season. This time around, Jones will still be missing Pearsall but has Jennings and Kittle back in his arsenal. Jones projects as a mid-range QB2, making him viable in two-QB formats.
--Dan StephensSource: Bay Area News Group - Cam Inman
November 8, 2025
Seattle Seahawks wide receiver
Jaxon Smith-Njigba should continue to dominate fantasy football in Week 10 against the Arizona Cardinals. Although the Cardinals are No. 11 against opposing wide receivers in fantasy, Smith-Njigba has proven himself to be matchup-proof this season. The Cardinals are the only team to hold Smith Njigba to less than 96 yards or 18.3 fantasy points this season. However, that game was played in Week 4. A lot has changed since then, and Smith-Njigba has evolved into perhaps the best wide receiver in the league at the moment. Since Week 4, Smith-Njigba has not recorded fewer than 123 receiving yards or 22 fantasy points. He is about as automatic as they come. With the Seahawks' offense reaching such a high level over the last few weeks, Smith-Njigba has a great chance to continue his stats in both categories. Nobody is going to bench Smith-Njigba while he is playing like this, but you can expect another monster game in Week 10 from the third-year man.
--Quincy Milton III - RotoBallerSource: RotoBaller
November 8, 2025
Seattle Seahawks kicker
Jason Myers should have plenty of chances to rack up points on Sunday against the Arizona Cardinals. Myers has always been an accurate kicker, but Seattle's ascension as an office is providing Myers with a lot of shots at field goals and extra points. Myers enters Week 10 averaging 9.75 fantasy points as a kicker. He is providing your team with legitimate low-end flex value in your kicker spot. Best of all, Myers is doing so consistently. He has reached double-digit fantasy points three times this season. The Cardinals boast a solid defense, but they will be traveling to Seattle in Week 10. The home-field advantage should help Seattle be successful offensively. Trust Myers as a high-end kicker option in Week 10 and beyond.
--Quincy Milton III - RotoBallerSource: RotoBaller
November 8, 2025
Seattle Seahawks running back
Zach Charbonnet has been wildly inefficient and ineffective this season. However, he remains fantasy relevant because his role at the goal line is netting touchdowns. Charbonnet will face a solid Cardinals defensive front in Week 10 as he continues to split time with fellow running back
Kenneth Walker III. Either way, Charbonnet's inefficiencies make him difficult to trust as a legitimate starter for fantasy this week. Fortunately, Seattle's offense should have no issue moving the ball up and down the field against the Cardinals. Charbonnet already scored on this team in Week 4, and he should have had a second score in that game. With another four teams on bye in Week 10, you could throw Charbonnet in your flex and hope for a touchdown. He is a better bet than what you are likely able to scrape together on the waiver wire this week.
--Quincy Milton III - RotoBallerSource: RotoBaller
November 8, 2025
The Seattle Seahawks D/ST is a quality option in Week 10 against the Arizona Cardinals. This defense continues to get healthier, with most of its top options available this week. Additionally, Arizona's offense does not inspire a whole lot of confidence. Although Cardinals backup quarterback
Jacoby Brissett has brought a new level of respectability to the unit, the Cardinals are still susceptible to sacks and negative plays that are a dream for D/STs in fantasy. There should be plenty of opportunities for Seattle's defense to create both in Week 10. They may even be able to force a turnover or two with their swarming mentality. While the Seahawks D/ST is not No. 1 in the league, they have been virtually matchup-proof. This unit has scored less than 8 fantasy points just once this season. That does not figure to change in Week 10. Start the Seahawks D/ST with confidence this week.
--Quincy Milton III - RotoBallerSource: Seattle Seahawks
November 8, 2025
Seattle Seahawks running back
Kenneth Walker III has been a fantasy disappointment this season; however, Walker could deliver flex value in Week 10 against the Arizona Cardinals. Arizona has a good-but-not-great defense this season. Walker already carved them up to the tune of 110 total yards in Week 4. Walker has been held in check since then, never topping 9.6 PPR fantasy points. Still, Walker is consistently receiving double-digit opportunities. It is only a matter of time before he breaks off a big run. Seattle's offense is in a serious rhythm at the moment. They are throwing the ball extremely effectively, but they could improve on the ground. Look for Walker to have a bit of a bounce-back game this week to get the Seahawks' running game going again. If you need a flex play with upside, Walker could be your man in Week 10.
--Quincy Milton III - RotoBallerSource: RotoBaller
November 8, 2025
Seattle Seahawks quarterback
Sam Darnold should be a quality option at the position in Week 10 against the Arizona Cardinals. Darnold has been on a tear recently. He is coming off an impressive four-touchdown performance against the Commanders in Week 9. Darnold is comfortable in the offense, and it shows. The matchup with the Cardinals is not scary. While Arizona does boast a solid defense, Darnold already took advantage of this matchup in Week 4. The Cardinals have not seen an offense as dialed in as Seattle's yet this season. As such, Darnold has a great chance to exceed the 16.08 fantasy points he scored in Week 4. As long as wide receiver Jaxson Smith-Njigba continues to play at a high level, Darnold will succeed for fantasy. Start him as a quality QB1 in Week 10.
--Quincy Milton III - RotoBallerSource: RotoBaller
November 8, 2025
New York Giants' Defense is a clear fantasy football bench candidate for Week 10, facing a Chicago Bears offense that is clicking on all cylinders and presents a nightmare matchup. The Giants' DST is struggling significantly, allowing an average of 27.7 points per game (28th in the NFL) and 382.1 total yards per game (29th), indicating a unit highly susceptible to big plays. Compounding the issue, they face a Bears offense led by
Caleb Williams, ranked 4th overall, averaging 26.9 points per game (6th in the NFL). Given the Giants' 30th-ranked Red Zone defense, which permits a 70% touchdown rate, this poor unit should be avoided in all fantasy formats against Chicago's high-octane attack.
--Danny BoilySource: NFL.com
November 8, 2025
New York Giants tight end
Daniel Bellinger is showing subtle signs of increased involvement in the offense, making him a speculative play in deep fantasy leagues for Week 10 against the Chicago Bears. While Bellinger is the 35th-ranked fantasy TE, averaging just 3.86 points per game, he is benefiting from rookie QB
Jaxson Dart's tight end targets and the team's increased use of two-tight end sets following major receiver injuries. Bellinger's impressive 17.6 yards per reception shows an unexpected deep-threat element that could exploit the Chicago defense's weakness, as they have allowed 20 passing touchdowns on the season. Although Chicago is an average matchup against the TE position, this vulnerable defense (28.4 points allowed per game) offers a glimmer of hope that Bellinger could score a sneaky touchdown.
--Danny BoilySource: NFL.com
November 8, 2025
New York Giants wide receiver
Jalin Hyatt is receiving another opportunity to prove his fantasy value in Week 10 against the Chicago Bears. Yet he remains an unreliable option given his minimal production this season. Hyatt has done little with his chances, registering only three receptions for 17 yards on the year, making him essentially unplayable in fantasy leagues. The silver lining is the opponent: the Bears rank 30th against WRs, giving up a league-high 38.63 points per contest. Furthermore, Chicago has allowed 20 passing touchdowns on the season, indicating a high-scoring environment where Hyatt could benefit from a deep shot. Still, based on his season-long performance of only five targets, he is not to be started in any leagues.
--Danny BoilySource: NFL.com
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