Starts and Sits - All Starting Pitcher Matchups for Fantasy Baseball (September 22 - September 28)

September 28, 2025

Nick's fantasy baseball starts/sits, expert advice for all starting pitcher matchups for September 22 - September 28 (2025). Set your winning fantasy baseball lineups.

It's the final countdown, with the last week of the fantasy baseball just waiting to be conquered with our starting pitcher starts/sits for fantasy baseball Week 26 - Monday, September 22 through Sunday, September 28. This column provides readers with who is pitching, the opponent, and a confidence/startability score based on an array of metrics. Keep us bookmarked for every start/sit option and two-start decision that remains between you and that last push to glory!

For 13 years running, we have been writing this Starting Pitcher Starts and Sits series weekly here at RotoBaller. I'm Nick Mariano, and I'll take us through the 2025 season. All types of firepower go into bringing you this piece each week, as we provide a must-read series for our readers.

Newcomers should be sure to read the section below to learn the column's goal and how best to use this tool, while long-time RotoBallers can proceed to the guide. We wish you the best of luck with your fantasy baseball starting pitcher decisions, but ideally, we create our own luck with informed decision-making. This last week will be hectic, with all sorts of shuffling assignments as teams rest veterans and dinged-up arms, while contenders line up their rotations for the playoffs.

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Start/Sit Data Overview

Ahead of each week of the fantasy baseball season, we publish the table below. We have the probable starters for every game of the week and a grade for them on a 0-100 scale. The intent is to give you advice and inspire confidence (or lack thereof) in your decisions to start or sit certain pitchers.

Please note that beyond the usual "Start" and "Sit" labels, we've expanded on the old "context-dependent" section to break it down further with "Lean Sit," "Lean Start," and true 50/50 "Coin Flip" designations. This is because different leagues call for different actions, and those in start-sit purgatory may be worth the gamble to some.

Also, we put the arms best projected to start or get bulk innings or actionable arms who may return from the injured list or be called up. Still, some situations are fluid, and we update ASAP to reflect accurate information. Be sure to stay tuned as we reflect the news for playoff contenders and those out of the race announcing who will miss their final regular season turn.

The "starts" category includes pitchers you'd likely start in every league. The "sits" are pitchers you likely sit in every league.

The 40-60 range will mean it is close, and it's up to you to decide based on your league settings or team needs (wins, strikeouts, etc.), how deep your league is, which roto/points categories are scored, and so on.

Here are your starts and sits for what we're calling Week 26 of the fantasy season and covers September 22 through September 28.

Week 26 Start/Sit Recommendations (September 22 - September 28)

Updated start/sit recommendations for this week's MLB games. This chart is updated daily as probable starters are constantly changing with postponements, injuries, etc. Scroll down further for a color-coded chart. If you can't see the chart below, click here to see the starts/sits on a separate page:

Start/Sit Color-Coded Matchups Chart (September 22 - September 28)

The below grid shows the same data but as a color-coded grid:

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