FanDuel MLB Lineup Picks (9/25/21): Daily Fantasy Baseball Advice

Kyle Ringstad highlights the top FanDuel MLB DFS lineup picks for 9/25/21, and a couple of sleepers to consider while building daily rosters.

We have a nine-game slate on the blue site tonight as the season winds toward its final week. There are numerous ways to go with pitching tonight, but I strongly prefer paying up to get to one of the top hurlers as the opportunity cost of missing out on those raw points can't be overstated. It is a Coors Field slate, but there are enough attractive stacking options that we can feel comfortable getting to outside of Colorado. Let's get to it.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 9/25/2021. You can see our DraftKings and FanDuel DFS lineup pick for the early slate here as well.

Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also check out today's DraftKings MLB DFS lineup picks, and read more DFS advice and lineup picks for other sports too. Let's get to it!

FanDuel DFS Pitchers

Cash Game / GPP Anchor Play:

Corbin Burnes - MIL vs. NYM ($11,200)   

Burnes has been absolutely incredible all season, and you're going to want to get a lot of exposure to him tonight. He has the highest ceiling and median projection on this slate, and it's not all that close. The flamethrower has three outings with at least 71 FD points over his last 11 starts - I'm not certain there's another pitcher in the entire MLB who has shown that kind of ceiling that frequently. He holds a minuscule 2.34 ERA and ranks in the top 3% of the league in xwOBA, xERA, xSLG, Barrel %, K%, Whiff %, and Chase Rate. He put up a modest 38 FD point score in his last outing against the Mets as he had eight punchouts but failed to record the win or quality start. The Mets aren't anything special against RHP and they hold a low 3.1-run implied total and Burnes is my top pitcher on the slate.

GPP Alternate Play(s)

Robbie Ray - TOR vs. MIN ($10,800)

Here's a chance to get a high-caliber pitcher in a great spot, and he may come at lower rostership due to his disappointing and abbreviated outing in his last start against the Rays. He only had five strikeouts in that one, but he was absolutely on fire prior to that as he had put up between 55 and 67 FD points (with 10-14 K's) in five of his previous six starts. Ray has simply been incredible all season as he finally figured out his control issue and his elite 32.8% strikeout rate and 2.72 ERA make him appealing in DFS. The Twins will trot out a lineup that can be attacked, especially with a left-handed pitcher. Since July 1st, the Twins are striking out at the sixth-highest rate (23.8%), hold the third-lowest OPS (.685), seventh-lowest ISO (.145), and fourth-lowest wOBA (.300) vs. LHP. The bottom half of the lineup has a lot of strikeouts in it, including the MLB leader Miguel Sano and his monstrous 34.8% K%.

Others: Rich Hill (vs. MIL), Jaime Barria (vs. SEA), Lance Lynn (vs. CLE)

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FanDuel DFS Infielders

Adam Frazier -  2B, SDP vs. ATL ($2,500)

Frazier is hitting .322 in September after a few down months and while he's not going to hit for power, he can certainly exceed value at his price tag here. He hits RHP much better and opposing pitcher Ynoa has a 5.12 ERA over his last four starts.

Eugenio Suarez - 3B/SS, CIN vs. WSH ($2,900)

Suarez has been one of the worst hitters in the MLB this season, but the beauty of DFS is that we only need to concern ourselves with the one game at hand. Suarez is suddenly scorching hot with a 1.184 OPS in September and seven hits over his last four games. He has two homers, a double, three RBI, and three runs scored in that stretch, and he absolutely can provide value at his low price tag here against Fedde (eight HR allowed over his last four starts) and the Nationals.

Trey Mancini - 1B/OF, BAL vs. TEX ($2,900)

Mancini hasn't been in great form and he hits much worse against RHP, but Jordan Lyles is no ordinary RHP. Lyles allows a ton of run production and power, as evidenced by his 7.60 ERA and 11 HRs allowed in August. Mancini is cheaper than a player with his hitting profile should be and this looks like a spot where he can provide incredible value against an overmatched pitcher.

Others: Eric Hosmer (vs. ATL), Ketel Marte (vs. LAD), Ryan McMahon (vs. SFG)

FanDuel DFS Outfielders

Cedric Mullins - OF, BAL vs. TEX ($3,500)

Jordan Lyles is the king of allowing the long ball (37 HRs over 28 starts), so we have to take a hard look at some Orioles in this spot. Mullins is my favorite as he's at a reasonable price point and leads the team with a .263 ISO, .400 wOBA, and 20 HRs vs. RHP this season.

Nick Castellanos - OF, CIN vs. WSH ($3,800)

Castellanos has rebounded nicely from a tough stretch in July as he posted a .826 in August and is rocking a .844 OPS and September, with six homers in each month. Fedde has weak metrics overall and has allowed a whopping eight bombs over his last four starts, including two starts where he gave up three long balls.

Leody Taveras - OF, TEX vs. BAL ($2,200) 

Taveras does not have pretty numbers no matter how you slice it, but he gets a favorable pitching matchup and is in decent form with hits in three of his last four games, including two doubles and two runs scored. Opposing pitcher Chris Ellis is nothing to write home about and Taveras could be a sneaky value play at just $2,200. Work him in if he's leading off, but he loses a lot of appeal if he's hitting in the nine-hole.

Others: Adolis Garcia (vs. BAL), Trent Grisham (vs. ATL), Aristides Aquino (vs. WAS)

FanDuel DFS Stacks

• CIN vs. Fedde
• BAL vs. Lyles
• TOR vs. Gant
• CWS vs. Morgan
• LAD vs. Gallen
• SFG/COL in Coors

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