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Sep 25, 2026, 7:32 PM ET

San Francisco 49ers wide receiver Deebo Samuel Sr. has elevated fantasy value ahead of his team's divisional standoff against the Arizona Cardinals. The veteran wideout has had a modest return to the Bay Area, with nine catches on 11 targets for 79 yards and one touchdown, plus two carries, to start his 2026 campaign. His target share should increase in Week 3, however, with fellow receivers Mike Evans (hip) listed as questionable, and Demarcus Robinson (ankle) and De'Zhaun Stribling (ankle) both out. Arizona has allowed 24 receptions for 329 yards and four touchdowns by wide receivers to start the season, which boosts Samuel's appeal. He is a solid WR3 and flex option going up against the Cardinals at home.--Chelena Goldman
Source: ESPN
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Sep 25, 2026, 7:31 PM ET

Tampa Bay Buccaneers wide receiver Chris Godwin Jr. has hauled in every pass thrown to him through the first two weeks of the season. Godwin has seven receptions in two games, but it has only resulted in 86 yards, and he hasn't reached the end zone yet. It hasn't been a bad start to the year for Godwin, but he could get lost in the shuffle in Tampa Bay. The Bucs have a crowded group of receivers, and the passing attack isn't working great early in the season. Godwin should stay involved, but his value might cap out as a flex option. He'll draw a tough matchup in Week 3 against the Minnesota Vikings defense that didn't allow a passing touchdown last weekend.--Andy Webb
Source: Pro Football Reference
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Sep 25, 2026, 7:27 PM ET

Philadelphia Eagles running back Tank Bigsby (abdomen) was listed as a limited participant in practice on Friday after he was held out of Thursday's session, according to the team. Running back Will Shipley (foot) followed the same path after suffering a foot injury in the Week 2 win over the Tennessee Titans. Bigsby had a bigger role this past Sunday after Saquon Barkley left to be evaluated for a stinger. The 25-year-old carried the ball 13 times for 33 yards and scored his first rushing touchdown of the 2026 season. Bigsby also caught both of his targets for five yards through the air. Fantasy managers who scooped Bigsby up off the waiver wire this week were hoping that he might be the Eagles' starting back on Monday night in Week 3 against the Chicago Bears with Barkley injured, but Barkley has upgraded to a full practice and is set to be active. In the season-opening win over the division-rival Washington Commanders, Bigsby only saw one carry for three yards. He will not have standalone fantasy value if he is active on Monday, but he is still one of the best upside handcuff options at the position in fantasy.--Keith Hernandez
Source: Philadelphia Eagles
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Sep 25, 2026, 7:20 PM ET

Philadelphia Eagles wide receiver DeVonta Smith (hamstring) was listed as a limited participant in practice on Friday, according to the team. It is great news for Smith's fantasy managers after he did not take part in Wednesday's practice due to a hamstring injury. The 27-year-old should be on the right track to suit up on Monday night in Week 3 against the Chicago Bears, but it is worth keeping a close eye on his status going into Saturday. Remember, tight end Dallas Goedert (knee) has not practiced at all this week and is expected to miss multiple weeks with a knee injury that he suffered in the Week 2 loss to the Tennessee Titans. With both Goedert and Smith banged up, it could put more emphasis on receivers Dontayvion Wicks and rookie first-rounder Makai Lemon going into the Week 3 contest. Smith is Philly's new WR1 with A.J. Brown out of town and is a must-start in fantasy leagues when he is active. The former first-rounder in 2021 came alive this past Sunday, catching 10 of his 13 targets for 117 yards and his first touchdown of the season.--Keith Hernandez
Source: Philadelphia Eagles
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Sep 25, 2026, 7:16 PM ET

San Francisco 49ers tight end George Kittle has returned to top-tier TE status and is set to have an increased workload in Week 3 against the Arizona Cardinals. The veteran had a quiet start to his 2026 campaign as he worked his way back from offseason Achilles surgery, but broke out in Week 2 by catching all four of his targets for 80 yards and a touchdown against the Miami Dolphins. The 49ers have a banged-up receiving corps heading into Sunday's matchup, with Mike Evans (hip) listed as questionable and Demarcus Robinson (ankle) joining De'Zhaun Stribling (ankle) on the sidelines. That shouldn't put too much pressure on Kittle, though, considering the Cardinals defense has struggled against the pass to start the 2026 season. Kittle returns to starter status as a mid-range TE1 in Week 3.--Chelena Goldman
Source: ESPN
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Sep 25, 2026, 7:12 PM ET

Tampa Bay Buccaneers wide receiver Emeka Egbuka has been held in check during the first two games of the season. Coming into Week 3, Egbuka has recorded eight receptions for 79 yards with one touchdown. The Bucs offense has struggled as a unit during the first two weeks of the season. It's unlikely going to get much better against the Minnesota Vikings defense in Week 3. A defensive unit that didn't allow a single passing touchdown to the Chicago Bears last week. Egbuka offers big-play ability that makes him difficult to ignore. Fantasy managers should lower their expectations, but Egbuka should be able to at least give low-end WR2 value this weekend.--Andy Webb
Source: Pro Football Reference
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Sep 25, 2026, 7:05 PM ET

Philadelphia Eagles running back Saquon Barkley (neck) said he is feeling good this week and will be wearing a neck cowboy collar on Monday night in the Week 3 game against the Chicago Bears, according to Dave Zangaro of NBC Sports. Barkley underwent an MRI exam early this week to make sure there was no additional damage in his neck/shoulder after he suffered a stinger in the Week 2 win over the Tennessee Titans on Sunday. The Eagles listed Barkley as limited in practice on Thursday, but he was able to upgrade to full on Friday, suggesting he could be cleared from the final Week 3 injury report on Saturday. Backup Tank Bigsby (abdomen) came out of Sunday's game with an abdomen issue, but he was able to return to a limited practice on Friday after being held out on Thursday. Barkley gave his fantasy managers a dud in Week 2 with only four carries for nine yards and one catch for 11 yards, but he will be back in must-start territory against the Bears on Monday night now that he has recovered from the stinger he suffered on Sunday.--Keith Hernandez
Source: NBC Sports Philadelphia - Dave Zangaro
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Sep 25, 2026, 7:00 PM ET

Tampa Bay Buccaneers running back Kenny Gainwell is off to a slow start with his new team. Through two games, Gainwell has rushed for 25 yards on seven carries, while hauling in four passes for an additional eight yards. Fantasy managers expected much more from Gainwell, who caught a career-high 73 passes with the Pittsburgh Steelers last season. His value could be on the rise with Bucs' offensive coordinator Zac Robinson saying the team wants to have lead back Bucky Irving on a pitch count. It's tough to imagine Gainwell offering a ton of upside against a tough Minnesota Vikings defense in Week 3. He could be a flex option in PPR formats, but most fantasy managers can probably leave him on the bench right now.--Andy Webb
Source: Pro Football Reference
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Sep 25, 2026, 6:56 PM ET

Tampa Bay Buccaneers running back Bucky Irving has been impressive on the ground over the first two games of the season. He rushed for 89 yards last week on 17 carries in the loss to the Cleveland Browns. Fantasy managers shouldn't expect that to happen every week with Bucs' offensive coordinator Zac Robinson saying Irving will be on a pitch count. It sounds like the Bucs are going to try to limit Irving in an attempt to keep him healthy all season long. The loss of touches is going to impact his value, and he gets a tough matchup in Week 3. He'll be running against a Minnesota Vikings defense that hasn't allowed a rushing touchdown this season. His overall ceiling might be limited, but Irving should still offer RB2 value.--Andy Webb
Source: Pro Football Reference
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Sep 25, 2026, 6:55 PM ET

San Francisco 49ers running back Kaelon Black could be a sneaky fantasy asset in Week 3 against the visiting Arizona Cardinals. The rookie back is still looking for his first regular-season touchdown but has made the most of his opportunities thus far, logging 21 carries for 90 yards through his first two games. The 49ers are favored in Sunday's matchup and the Cardinals' defense is spotty, allowing 243 rushing yards over two games. An early advantage, especially on the ground, could lead San Francisco to ease off star RB Christian McCaffrey and give Black more opportunities. The Indiana product still doesn't play enough to be viable in redraft fantasy leagues, but has become a valuable stash in deeper formats.--Chelena Goldman
Source: ESPN
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Sep 25, 2026, 6:53 PM ET

San Francisco 49ers running back Christian McCaffrey has the opportunity to bounce back when his team hosts the Arizona Cardinals in Week 3. The star back was part of a large contingent of players who didn't participate in Wednesday's practice but returned on Thursday to prepare for Sunday's divisional matchup. McCaffrey was held to 23 yards on 10 carries in Week 2 but scored two rushing TDs in a convincing 35-13 win against the Miami Dolphins. Arizona has struggled to contain the run early in the 2026 campaign, allowing 243 yards and one touchdown on the ground through two games. CMC should be able to exploit the Cardinals' defense, setting the table for a strong Week 3 across fantasy leagues.--Chelena Goldman
Source: ESPN
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Sep 25, 2026, 6:51 PM ET

Tampa Bay Buccaneers quarterback Baker Mayfield is off to a slow start to the season. Through two games, Mayfield has thrown for 398 yards with one touchdown and one interception. Fantasy managers expected more from Mayfield out of the gate, given his success under center since joining the Bucs in 2023. It's unlikely going to get better for Mayfield this weekend against the Minnesota Vikings defense. A defensive unit that didn't allow a passing touchdown to the Chicago Bears in Week 2. At some point, Mayfield should turn a corner, but until then, fantasy managers should put him in the QB2 conversation for Week 3.--Andy Webb
Source: Pro Football Reference
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Sep 25, 2026, 6:50 PM ET

San Francisco 49ers quarterback Brock Purdy takes his league-leading completion percentage (80.4%) into divisional play in Week 3 against the Arizona Cardinals. No. 13 was at the top of his game in Week 2, completing 20 of 22 passes for 287 yards and two touchdowns in a 35-13 win against a leaky Miami Dolphins defense. The Cardinals' d-corps has been a mixed bag to start the season, shutting down the Los Angeles Chargers offense in Week 1 but allowing Seattle Seahawks' QB Drew Lock to throw for 235 yards and three touchdowns in Week 2. Even with wide receiver Mike Evans (hip) listed as questionable and Demarcus Robinson (ankle) officially out for Sunday, Purdy has had plenty of success spreading his targets around the receiving corps. Purdy is elevated to a high-end QB1 in Week 3 against an inconsistent Arizona defense.--Chelena Goldman
Source: ESPN
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Sep 25, 2026, 6:49 PM ET

Las Vegas Raiders wide receiver Jack Bech still has sleeper potential heading into Week 3, even with Brock Bowers' (knee) return looming ahead of a road rumble against the Saints in New Orleans. Bech caught 100% of his targets in Week 2, but it was just two catches for 25 yards, and he didn't add to his season touchdown total. Kirk Cousins has spread the ball around through his first two games in Silver and Black, so Bech will have to work for his targets with or without Bowers potentially returning to the gridiron on Sunday. The second-year wideout doesn't produce enough for redraft league impact, but he remains a deep-league stash.--Chelena Goldman
Source: ESPN
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Sep 25, 2026, 6:47 PM ET

Carolina Panthers running back AJ Dillon is stepping into the team's No. 2 role with running back Jonathon Brooks (core) set to miss extended time. However, this will likely remain the Chuba Hubbard show in Carolina's backfield, and Dillon is not on the fantasy radar in Week 3 against the Cleveland Browns. Hubbard figures to receive the lion's share of work in Carolina's backfield. Dillon could find his way into a goal line role given his massive frame, but fantasy managers would be in a better position to wait and see what will happen before even rostering Dillon. For now, leave Dillon on waivers and watch how the snap share shakes out in Week 3.--Quincy Milton III - RotoBaller
Source: RotoBaller

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