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FanDuel Lineup Picks (Week 16) - NFL DFS Advice

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 16 of the NFL season. In this article I will be taking you through the best FanDuel DFS value plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

 

FanDuel Quarterbacks - Week 16 DFS Picks

Russell Wilson (@DAL, $9,000)

  Wilson is a tough sell in a couple ways, mostly that he is the highest priced quarterback on the main slate. However, he is also intriguing in two important ways. First, prior to his disastrous Week 15 performance, he had been on an absolute tear and shown the ability to pay off his price tag. He could also go overlooked in a positive matchup as the Seahawks seem to have been dismissed by many across the league.

Blake Bortles (@SF, $7,600)

The 49ers have shown a lot of improvement since the introduction of Jimmy G as the starting quarterback, but one way that hasn’t translated is to their pass defense. The Niners have allowed multiple passing touchdowns every week since Week 6 with exception only in their matchup against Mitchell Trubisky. Meanwhile, Blake Bortles has suddenly become a consistent fantasy force. Even with Leonard Fournette back in the lineup, Bortles should have a good shot at a multi-touchdown performance.  

 

FanDuel Running Backs - Week 16 DFS Picks

C.J. Anderson (@ WAS, $6,200)

It appears the Broncos have turned back to C.J. Anderson as their lead back as he has had a floor of 19 touches over the past three weeks. He has shown the ability to pay off his price tag as well, posting well over 2X value in two of those three weeks. Now, he will get a Washington defense that has gotten gashed by opposing running game several times over the past few weeks. His price hasn’t risen enough to be a deterrent so look his way this week.

Theo Riddick (@ CIN, $6,100)

The Bengals have officially mailed it in and that has been quite apparent in the way running backs have performed against them. Looking to Jerick McKinnon’s line against them last week, 24 rushing yards to go along with 114 receiving yards, is a good place to start in thinking about what could be for Riddick this week. As the lead back in both the rushing and receiving game, he’s a solid bet for over 100 total yards, making 2X value a probable outcome. If he can add a touchdown to that, 3X is well within reach.

 

FanDuel Wide Receivers - Week 16 DFS Picks

Doug Baldwin (@DAL, $7,300) 

Baldwin had a dismal Week 15 performance, posting just one reception for six yards on four targets. What’s lost in that line is the fact that Russell Wilson missed Baldwin on a deep pass early in the first quarter, a catch that would have given Baldwin a third consecutive game with at least one catch of 40 yards. This week, weather won’t be an issue in Dallas which should allow the Baldwin-Wilson connection to get back on track against a vulnerable Cowboys secondary.

Mike Evans (@CAR, $7,000)

Evans put in a bounce back performance in Week 15 against the Falcons, which was dependent on a long touchdown. He still only had eight targets, which is troubling. On the other hand, there are several indications that he should be targeted more heading into Week 16.  First, Jameis Winston acknowledged this week that he needs to get Evans the ball more often. In addition, Friday's news that DeSean Jackson is out means that there are less places for the Bucs to spread targets. Evans price remains down to the point where he no longer needs a massive game to pay off value and the Panthers' secondary isn't as good as many may assume.  

 

FanDuel Tight End - Week 16 DFS Pick

Travis Kelce (vs. MIA, $7,000)

After a down week and having gone two games without finding the end zone, Kelce’s price has dipped to his lowest of the season. That’s something to take advantage of against a Dolphins team that was torched for 84 yards and two touchdowns by Rob Gronkowski. The Chiefs should look to ride their trio of stars at home in an effort to wrap up the AFC West, with Kelce being a big part of that.  

 

FanDuel Defense - Week 16 DFS Pick

Kansas City Chiefs (vs. MIA, $4,500)

Matchups against Jay Cutler should be circled at this point as it became pretty clear he has lost interest in being on the football field last week. That should allow a motivated Chiefs defense to rack up turnovers, with the key being that this game is being played at Arrowhead.

 

More Weekly DFS Analysis





REAL-TIME FANTASY NEWS

Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Cam Skattebo

Dynasty Stock Rising Following NFL Draft
Kaleb Johnson

Logging First-Team Reps in OTAs
Evan Engram

Dynasty Value Fading After Production Decline in 2025
TreVeyon Henderson

Dynasty Outlook Clouded By Split Backfield in New England
Caleb Williams

' Dynasty Upside Remains Sky-High Entering 2026
Bijan Robinson

Is Bijan Robinson the No. 1 Overall Player in Dynasty Formats?
Woody Marks

Should Have Plenty of Opportunities to Catch Passes
Drew Allar

Working as QB4 in First OTA Session
Aaron Rodgers

Reports to Steelers Facilities on Monday
Alvin Kamara

Saints Remain Non-Committal on Alvin Kamara's Future
Chris Olave

Saints Continue to Work on Extension With Chris Olave
Parker Washington

a Sneaky Trade Target in Dynasty Leagues?
Melquizael Costa

Drops Decision At UFC Vegas 117
Jarquez Hunter

Can Jarquez Hunter's Dynasty Outlook Improve in Year 2?
Arnold Allen

Bounces Back
James Conner

Off the Dynasty Radar Entirely?
Elijah Arroyo

Will Elijah Arroyo Continue to Have Trouble Getting on the Field?
Daniel Santos

Suffers Second-Round TKO Loss
Tre Tucker

Not a Long-Term Solution in Dynasty Leagues
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jack Bech

a Dynasty Hold as New-Look Raiders Offense Takes Shape
Jaydon Blue

a Low-Value Dynasty Stash Until Depth Charts are Settled
Makai Lemon

a Top-Five Pick in Dynasty Rookie Drafts
George Kittle

a Dynasty Buy with League-Winning Potential
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Chris Rodriguez Jr.

a Dynasty Sleeper with High Touchdown Potential
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Donovan Mitchell

Guides Cavaliers Into East Finals
Sam Malinski

Practices Fully Sunday
Jarrett Allen

Scores 23 Points in Cavs' Game 7 Rout of Pistons
Josh Manson

Rejoins Practice
Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Bones Hyland

Wants to Stay in Minnesota
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF