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Break The Slate: NFL DFS DraftKings Lineup Picks - Week 4

The top daily fantasy football lineup picks for DraftKings in Week 4 of 2019. Joe Nicely's NFL DFS analysis and sleepers for building optimal DFS rosters.

Hello again RotoBallers and NFL DFS fans! Thanks for joining me here at Break The Slate, a weekly article in which we try to pinpoint the best DraftKings plays available on the main slate. One of the most interesting things about NFL DFS is how different each slate is from week to week. Frankly, there's a lot of matchups that I have no interest in this week, so the Week 4 selections below mainly come from the handful of games that I'm specifically targeting on this slate.

These DraftKings lineup recommendations are based on matchups, projected ownership, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home field advantage, and more. There are quite a few great plays available, so read on to find out which players are the best for Week 4.

Good luck with your DraftKings DFS lineups, lets Break The Slate together!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 4 Picks

Russell Wilson - SEA @ ARI ($6,100)

I love this game all the way around (as you'll see throughout this week's article) and Russell Wilson specifically. The Seahawks are a team that strives to run the ball as much (or more than) any team in the league, which puts a cap on Russ' ceiling most weeks. Of course, fantasy players know that Seattle is actually a more effective offense when 'forced' to unleash Wilson and get aggressive, which they've had to do the last couple of weeks. It's led to 706 yards and 5 TDs through the air, and 73 yards and 2 TDs on the ground for Wilson in his last two games. Seattle is a road favorite in this game against Arizona, so we can't really project that they will be playing catchup this week, but Wilson will be aided heavily by two factors:

1.) Arizona plays at an extremely fast pace and has allowed opponents to run an insane average of 70.3 plays per game, which should give Russ plenty of opportunities.
2.) This Cardinals secondary is putrid (they've allowed the third-most DraftKings points and passing yards to opposing QBs in the NFL), while the defense as a whole has been somewhat effective at slowing down the run, which creates a natural pass-funnel situation.

Unfortunately, Wilson's offensive coordinator is always his biggest obstacle to huge fantasy scores, so there is a 'lower than we would like' floor here, but there is also a path to another explosive fantasy day for Russ.

Daniel Jones - WAS @ NYG ($5,300)

I know this feels 'point chasey', but like the aforementioned Seattle vs Arizona matchup, there's a lot to love about this game that carries a surprisingly-high O/U of 48.5 and a tight point spread. After a monster debut last week in which he posted almost 40 DK points, New York's Daniel Jones has received a massive price bump of...$300? So, 'Danny Dimes' remains very affordable and draws a juicy matchup against the Washington Redskins...and all this comes with Saquon Barkley no longer in the Giants lineup. The 'Skins provide a very beatable matchup for the rookie, as they rank bottom-five in the league in both DK points and passing TDs allowed to opposing QBs. Jones will also be aided by his own team's horrific defense, which should force the G-Men to remain aggressive when they do have the ball.

*SATURDAY UPDATE: I feel like I'm often guilty of glossing over Patrick Mahomes, but I think it's because I feel like you guys don't need to be told that he's in play. If there was any doubt, he is obviously a very strong play with a high floor and slate-breaking upside if you want to pay up at QB.

 

DraftKings DFS Running Backs - Week 4 Picks

Austin Ekeler - LAC @ MIA ($8,000)

My usual preference is to grab as many 'guaranteed' points as possible at the RB position, but there's not a lot to feel great about at the top of the board this week - as Christian McCaffery has to square off against an improving Houston run defense on the road and Dalvin Cook gets a nightmarish matchup against the Bears - which brings us to the Chargers' Austin Ekeler at $8k. Melvin Gordon's backup has dazzled as LA's full-time starter this season and he draws a mouth-watering matchup against the struggling Miami Dolphins this week. Ekeler has been solid on the ground (38 carries for 160 yards and 2 TDs) and spectacular through the air (catching 19 of 20 targets for 208 yards and 2 TDs). As you all know, the Dolphins run defense is about as bad as it gets...ranking dead-last in the NFL in DK points and rushing yards allowed to opposing RBs. With Melvin Gordon's return on the horizon and the Chargers standing at 1-2, I expect Ekeler to have some extra motivation this week and have a huge game against Miami.

Derrick Henry - TEN @ ATL ($6,300)

Derrick Henry isn't a player that I often roster on DraftKings (he generally sets up better for FanDuel scoring), but I'm willing to give the big Titans back consideration this week for a few reasons. As we already touched on, RB is a rather thin position this week and Henry's reliable usage is appealing. The Titans are holding fast to their commitment to Henry and the run game, as he's averaging 17 carries per game over their first three, and I was encouraged (from a fantasy perspective) by how Tennessee continued to feed Henry the ball last Thursday night despite falling behind early to Jacksonville. He gets a Falcons defense that is once again reeling this season and has been a terrific matchup for opposing RBs over the last couple of years. We think of Henry as a 'ground and pound' back, but he's proven himself capable of making splash plays, in addition to handling all of Tennessee's goal line work.

Chris Thompson - WAS @ NYG ($4,500)

New York's Wayne Gallman is probably the player you were expecting to see here - and I wouldn't argue with you for rostering him - but if you're playing a large-field GPP like the Milly Maker, a pivot to Washington's Chris Thompson is a very interesting way to gain leverage on big fields. Gallman should be one of the most popular RBs on the slate, while I expect the dependable Thompson to go largely overlooked. The 'Skins back won't garner as many carries as his NY counterpart, but he's been a reliable source of production in the Washington pass game, hauling in 16 of 23 targets for 195 this season. Thompson is an especially intriguing option for those of you that are looking to stack this game.

*SATURDAY UPDATE: L.A.'s Justin Jackson has been confirmed out, while Melvin Gordon will now be available in a small capacity, all of which makes me love Ekeler even more in this spot. Dalvin Cook has an absolutely brutal matchup against Chicago, but with his ownership trending at around 5%, he's a very intriguing option in large-field GPPs due to his talent and ability to break big plays. I will be keeping an eye on T.Y Hilton's status and will fire up Marlon Mack against the Raiders if Hilton sits. Kerryon Johnson is yet to have a big game, but it feels like one is coming.

 

DraftKings DFS Wide Receivers - Week 4 Picks

Tyler Lockett - SEA @ ARI ($6,300)

As I mentioned when discussing Seattle's Russell Wilson at QB, there's a lot I like about this Sea/AZ matchup. Tyler Lockett is in a true 'slate breaking' situation this week against a Cards secondary that is without Patrick Peterson and has allowed over 250 passing yards in every game this season. Arizona is also allowing opponents to run a shade over 70 plays a game on average, which bodes well for the unquestioned alpha of this Seattle receiving corps. Lockett has been targeted a RIDICULOUS 26 times over the last two weeks, hauling in 21 catches for 233 yards and a TD. It's always tough trying to guess when the Seahawks will be 'forced' to turn to Lockett, but the projected game environment doesn't get much better than this. His game-breaking explosiveness gives him enourmous upside, while his new-found volume brings his floor up to a very comfortable level. I love the idea of stacking him with Russell Wilson and one or two Arizona receivers.

Christian Kirk - SEA @ ARI ($5,100)

I'll make you guys a deal, when Christian Kirk gets less than 10 targets or gets priced above $6k, I'll stop writing him up in this article. Kirk heads into this matchup as a usage monster that's tied for third in the NFL in wide receiver targets at 32 through three games. I don't anticipate that volume to change this week, with a Seattle defense that focuses on stopping the run (Seattle has allowed just 176 yards rushing to opposing RBs) and an Arizona offense that is content to pass all day. The Cards lead the league in pass attempts per game at 45.7 and we can almost pencil in Kirk for at least his usual 10 looks. While the Seahawks secondary was once a feared unit, they are now nothing more than a middle-of-the-pack team against the pass. Kirk is averaging a very respectable 15.5 DK points per game despite having caught no touchdowns and he has a great chance to smash salary-based expectations this week.

Paul Richardson Jr. - WAS @ NYG ($3,700)

Some of you might remember that I jumped on Terry McLaurin way back in Week 2 (#TootMyOwnHorn) and I'm willing to continue rolling with another overlooked Redskins pass catcher this week. Paul Richardson is kinda ridiculously-priced at $3,700 on this slate, as his salary actually decreased by $500 despite a 22.3-point outing Monday night against the Bears (thanks for early pricing DraftKings!). Richardson was targeted nine times against Chicago and turned those looks into a 9/83/1 stat line. I'm looking for exposure to this game as a whole and I'm specifically targeting this struggling Giants secondary that is dead last in the NFL in both DK points and receiving yards allowed to opposing WRs. His volume expectation isn't as dependable as McLaurin's (and I wouldn't blame you if you wanted to pony up the extra $800 for McLaurin), but through Washington's three games Richardson has target counts of 9/3/7...numbers I can live with at $3.7k in this matchup.

*SATURDAY UPDATE: Washington's Terry McLaurin has popped up on the injury report. I'll be watching the situation very closely. If McLaurin goes I will have a combination of him, Richardson, and a stack of the two. If McLaurin is out, I'll be almost 'All In' on Richardson. Sticking with this game, I will mix New York's Sterling Shepard in with Richardson/McLaurin. As I alluded to when discussing Lockett & Kirk, I also like the other receiving pieces in this game like Larry Fitzgerald and DK Metcalf. L.A.'s Keenan Allen is once again a slam-dunk option. Atlanta's Calvin Ridley is always tough to predict, but he feels underpriced for the upside he brings to the table, while Carolina's Curtis Samuel seems to mesh well with new QB Kyle Allen at just $4,600.

 

DraftKings DFS Tight Ends - Week 4 Picks

Evan Engram - WAS @ NYG ($5,700)

I was on Evan Engram last week and he came through with a monster 26.3 outing against the Bucs. I'll go right back to the well here against the 'Skins. Engram's price has been raised by $500 in Week 4, but you can argue that it still isn't high enough at $5.7k. He's a target monster and has received 30 looks over New York's first three games. As we suspected, Daniel Jones' insertion into the lineup was a huge boost to Engram and I expect him to put himself in the 'best tight end behind Travis Kelce' conversation this season.

Will Dissly - SEA @ ARI ($3,600)

I'm sticking with this Seattle vs Arizona matchup at the TE spot. Will Dissly will be an extremely popular option this week, but I'm willing to swallow the chalk here at just $3.6k. Dissly's floor is lower than it appears (he's caught 3 TDs in his last two games), but his volume seems to be stabilizing at 5-7 targets a game. Arizona has been TORCHED by opposing tight ends this season and rank dead-last in the league in DK points allowed, receiving yards, and TDs allowed to the TE position. This combination of matchup and price makes Dissly tough to ignore.

*SATURDAY UPDATE: As I mentioned in Dissly's write-up, he will be extremely chalky, but he's hard to ignore in this spot at just $3.6k. Engram will also be popular, but remains my favorite play at the TE position. Oakland's Darren Waller appears to be gaining a little steam in the DFS community this week - and I get it - but a pivot to Baltimore's Mark Andrews in a bounce-back spot probably offers more upside.

 

DraftKings DFS Defenses - Week 4 Picks

New England Patriots - NE @ BUF ($3,700)

There's a legit argument for going up to the Chargers for just $100 more, as they get the Dolphins this week, but I'm comfortable with a "mini-pivot" to New England. The Patriots are playing great 'real world' defense and it has translated to fantasy goodness in the form of averaging 19.3 DK points through three games. This week's matchup against an improved Buffalo team might not look like a slam dunk at first glance, but we must keep in mind just how turnover prone Bills QB Josh Allen is. I expect Bill Belichick to find ways to force Allen into some bad decisions and wouldn't be surprised to see a Patriots defensive TD this week.

Los Angeles Rams - TB @ LAR ($3,500)

The Rams have a better defensive unit than they get credit for and this feels like a sneaky-good spot against Jameis Winston and the Bucs. Tampa Bay is fresh off an impressive offensive display against the Giants, but the Rams and Aaron Donald will present a much bigger challenge. Winston has only thrown four picks so far this season, but we know that his bad decisions can come in bunches and I'm willing to take a shot that L.A. can capitalize on some Winston mistakes in this spot.

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Jalen Hurts

Can Jalen Hurts Bounce Back as a Rusher in 2026?
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Zach Charbonnet

Dynasty Value in Question Entering 2026
DeVonta Smith

Poised to Reach a New Level of Production in 2026?
Chris Olave

Facing Increased Target Competition in New Orleans Entering 2026
Chris Bell

Dynasty Stock Rising Following NFL Draft
Ted Hurst

Facing Uphill Battle for Playing Time in Tampa Bay
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
Chris Brazzell II

Is Chris Brazzell II the Top Deep Threat in Carolina's Receiver Room?
Kaelon Black

a Threat to Win Backup RB Job in San Fran?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
De'Zhaun Stribling

to be 49ers' New "F" Receiver?
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
Drew Allar

Steelers "Uninstalling" Everything Drew Allar Learned in College
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Ja'Kobi Lane

Is Ja'Kobi Lane the Pass-Catching Answer the Ravens Have Been Seeking?
Zachariah Branch

Does Zachariah Branch Have a Path to Immediate Production?
Max Klare

Can Max Klare Separate Himself in Rams' Tight End Room?
Eli Stowers

the Tight End of the Future in Philadelphia?
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Germie Bernard

Already in a Tough Spot to Hold Dynasty Value
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Denzel Boston

a Smart Bet to Meet or Exceed Value in Dynasty Rookie Drafts
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Matthew Stafford

a Sell Candidate with Touchdown Regression Likely on its Way
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Jayden Reed

Dynasty Value Tethered to His Underwhelming Usage
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Kenyon Sadiq

Is Kenyon Sadiq the Next Great Rookie Tight End?
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Cade Klubnik

Becoming Fan Favorite, in Play to Win Backup QB Job?
Michael Penix Jr.

Throwing During Offseason Program
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Memphis Grizzlies

Brandon Clarke Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
Ajay Mitchell

Continues to Excel for Thunder
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
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