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Christian McCaffrey Matches Up Well Against Broncos
San Francisco 49ers running back Christian McCaffrey is in line for a productive Week 4 when he squares off against the Denver Broncos. So far in 2026, Denver has given up the third-most rushing yards, has the highest EPA allowed per run, and has the most missed tackles in the league. The Broncos defense will also be missing linebacker Dondrea Tillman (hamstring). This makes for an inviting matchup for McCaffrey, who owns the league's fifth-best rushing success rate and the highest average rushing yards before contact among starting running backs. As usual, McCaffrey can be expected to be one of quarterback Brock Purdy's favorite targets. And with Mike Evans (ribs) questionable and expected to be a game-time decision on Sunday, McCaffrey could see his receiving work increase. The Broncos gave up six catches for 70 yards to Kyren Williams last week. McCaffrey is projected as the overall RB6 in Week 4.
Source: NFL.com
Source: NFL.com
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Brock Purdy Still In QB1 Mix Despite Injuries To Receiving Corps
San Francisco 49ers quarterback Brock Purdy completed just 15 passes (out of 27 attempts) in Week 3, but he passed for a season-high 297 yards and four touchdowns in the team's 36-30 win over the Cardinals. Purdy is now up to 789 yards on the season, has a 72.3% completion percentage, and a league-leading nine passing touchdowns. Purdy may be without Mike Evans (ribs) in San Francisco's upcoming matchup with the Broncos, as the wide receiver is managing a rib injury sustained last weekend and will be a game-time decision on Sunday. Even without Evans, Purdy should remain an effective fantasy option, as he will still have Deebo Samuel Sr., George Kittle, and Christian McCaffrey at his disposal. Last week, Denver surrendered 390 passing yards and two touchdowns to Matt Stafford. Purdy is the overall QB2 after three weeks and projects as a top-five option in Week 4.
Source: NFL.com
Source: NFL.com
Tyjae Spears Officially Questionable for Road Outing
Tennessee Titans running back Tyjae Spears (ankle) is listed as questionable for Sunday's game against the Baltimore Ravens. Spears started the week as a non-participant but upgraded to limited, then to a full session on Friday. The Louisiana native has dealt with an ankle injury for a few weeks, though it didn't affect his ability to play in the team's Week 3 loss to the Giants. That said, it was Spears' least efficient game of the year thus far. Head coach Robert Saleh didn't seem concerned about the back's status earlier in the week, and a full practice to end the week should signal he has a good chance to suit up. If he does, the Tulane product is nothing more than a desperation long shot against the Ravens in fantasy.
Source: Tennessee Titans
Source: Tennessee Titans
TreVeyon Henderson in Prime Spot to Bounce Back
New England Patriots running back TreVeyon Henderson came back down to earth with an extremely quiet showing last Sunday, but we're still trusting him as a mid-to-low RB2 option ahead of Week 4 against the Buffalo Bills. Henderson had just eight carries for 23 rushing yards (plus one reception) last Sunday. The low volume can be attributed to the fact that New England had nothing going on offense and had to throw the ball more, but that's still something to consider as fantasy managers set their lineup for Week 4. The good news is that, even though Buffalo is favored by seven points, the Bills' defense has been iffy and should give Henderson an opportunity to bounce back after last week's dud. So far, Buffalo's run defense has allowed the seventh-most fantasy points, 10th-most rushing touchdowns, third-most receptions, third-most receiving yards, and second-most receiving touchdowns to opposing running backs in 2026. Game script aside, this matchup presents an extremely encouraging fantasy outlook for Henderson. He ranks as RotoBaller's RB25 in Week 4, but there's no disputing his top-15 upside.
Source: RotoBaller
Source: RotoBaller
Mason Taylor Deemed Out for Second Straight Game
New York Jets tight end Mason Taylor (thumb) has been ruled out for Sunday's road game against the Chicago Bears at Soldier Field. It's no surprise that the 22-year-old will miss a second straight appearance after not practicing since injuring his thumb in the team's 20-17 loss to the Packers in Week 2. The trio of Kenyon Sadiq, Jeremy Ruckert, and Jelani Woods will again divvy up the snaps with the second-year pro set to be inactive. It will be interesting to see how the snap share shakes out when Taylor returns to action. When healthy, he led the room by a solid margin, though that could change if Sadiq's Week 3 breakout weren't a fluke.
Source: New York Jets
Source: New York Jets
Drake Maye Worth Benching Amid Nightmare Start to Season
New England Patriots quarterback Drake Maye has endured a nightmare start to the season so far, and he's falling all the way to QB18 in RotoBaller's latest fantasy football rankings for Week 4. Maye had an extremely ugly stat line last week, including 199 passing yards and three turnovers, and he'll now head into an even tougher all-around matchup against the Buffalo Bills. The Bills' defense has been near the middle of the league this year, but we're more concerned about their elite offense and how that might speed Maye up or force him to attempt more passes on Sunday afternoon. If Maye can't keep pace with Josh Allen's squad early, it could be another long day in terms of turnovers and overall scoring. It also doesn't help that the MVP runner-up has been depleted of his top weapon, as he'll go at least two more weeks with AJ Brown (ankle) available. Between the tough divisional matchup and a weakened supporting cast, Maye can be benched in most single-quarterback leagues this week, even if you're replacing him in the lineup with someone you added off the waiver wire.
Source: RotoBaller
Source: RotoBaller
Kyren Williams Runs Into a Tougher Defense for Week 4
Los Angeles Rams running back Kyren Williams ranks as the overall RB11 in PPR leagues through the first three weeks of the season, but a Week 4 matchup against the Philadelphia Eagles hurts his ceiling and floor in fantasy football. Williams has been a busy pass-catcher in addition to running the ball this season, and he's best known for his work around the goal line. As a result, we're not thrilled that he's facing an Eagles run defense that has allowed the fewest receptions and fewest receiving yards to running backs. This Philadelphia unit has also limited running backs to one rushing touchdown and zero receiving touchdowns through three games. Managers aren't benching Williams on the heels of his 21.8-point (PPR) performance, but it may be necessary to temper expectations at least a little given how well the Eagles have played against the run this year. He's still hanging around as the RB9 in RotoBaller's latest fantasy football rankings for Week 4.
Source: RotoBaller
Source: RotoBaller
Matthew Stafford Gets His Elite Receiver Back for Week 4
Los Angeles Rams quarterback Matthew Stafford had already been producing high fantasy totals over the last two weeks, and now, his ceiling will soar even higher as he gets his top target back for Week 4 against the Philadelphia Eagles. Superstar wide receiver Puka Nacua has been cleared to play after a two-week absence due to a hip injury. Stafford will now benefit from having the league's best one-two punch in Nacua and Davante Adams. Although Nacua is the bigger name here, Adams filled in admirably with the 25-year-old sidelined. Over the last two weeks, Adams has 15 catches for 332 yards and two touchdowns. The veteran will return to his role as the No. 2 receiver in Los Angeles, but both he and Nacua are still in must-start consideration for Week 4. The same goes for Stafford, who gets to reap the benefits of throwing to some of the best receivers in the NFL. We're also intrigued by this matchup against the Eagles, who have allowed the seventh-most fantasy points to quarterbacks this season. Philadelphia has yet to intercept a pass, and its defense most recently surrendered 247 yards and three total touchdowns to quarterback Case Keenum. The stars are aligning for another big QB1 performance from Stafford in fantasy football.
Source: RotoBaller
Source: RotoBaller
Davante Adams Remains a Must-Start Despite Teammate's Big Return
Los Angeles Rams wide receiver Davante Adams has been playing at an elite level lately, but he might cool off in Week 4 against the Philadelphia Eagles. Teammate Puka Nacua has been cleared to return from his hip injury, dropping Adams back down to second in the pecking order in Los Angeles. It was an elite two-week stretch from Adams, who caught 15 passes for 332 yards and two touchdowns as the de facto alpha receiver for the Rams. Given how well he played with Nacua sidelined, we expect that he'll have no trouble remaining a strong fantasy option in most leagues going forward. After all, this is a high-volume offense that has shown it can support multiple fantasy-relevant receivers. As a result, we're still recommending all managers start Adams in Week 4 against the Eagles. He may not be a WR1 lock, but he has legitimate top-18 appeal at the wide receiver position. He should also benefit from this specific matchup against Philadelphia, which has surrendered the fifth-most touchdowns and 10th-most fantasy points to wide receivers in 2026.
Source: RotoBaller
Source: RotoBaller
Noah Fant Limited Again on Friday
New Orleans Saints tight end Noah Fant (abdomen) was a limited participant in Friday's practice as the team gears up for a Monday night home matchup against the Atlanta Falcons. That's two limited sessions to start the week for Fant, who has already scored three touchdowns in 2026. While it's unlikely he's been active on many fantasy rosters, the former first-round pick is the current TE14 in PPR formats. Whether that is sustainable remains to be seen, but Fant plays a decent amount of snaps on a high-powered, fast-paced offense and offers some appeal in deep leagues and best ball formats. If the 28-year-old is unable to suit up for Monday's contest, Treyton Welch and Oscar Delp figure to help fill the void behind Juwan Johnson in the Saints' attack.
Source: New Orleans Saints
Source: New Orleans Saints
Puka Nacua an Immediate WR1 in Highly Anticipated Return
Los Angeles Rams wide receiver Puka Nacua is immediately back in mid-to-high WR1 territory after being removed from the injury report ahead of Week 4 against the Philadelphia Eagles. Nacua sat out two games due to a hip injury, but he has been cleared to return for a battle between two strong offenses. The 25-year-old hasn't seen the field since the season opener, and a lot has changed for Los Angeles since then. The Rams looked their worst during that Week 1 battle; Matthew Stafford threw for 155 yards and one interception in that game, but 717 yards, six touchdowns, and three interceptions in two games since then. Davante Adams has been filling in admirably for Nacua, but the latter should return to his role as Stafford's favorite target and a must-start fantasy receiver in all leagues, especially with no reported limitations on his workload for Week 4. He'll also benefit from this specific matchup against the Eagles, who have allowed the fifth-most touchdowns and 10th-most fantasy points to wide receivers in 2026.
Source: RotoBaller
Source: RotoBaller
Javonte Williams Back In RB1 Territory For Difficult Week 4 Matchup
Dallas Cowboys running back Javonte Williams got back on track in Week 3 against the Baltimore Ravens by rushing 19 times for 98 yards and a touchdown and catching two of his three targets for five yards, finishing his day with 18.3 PPR fantasy points. The Cowboys clear RB1 was inefficient in his first two contests, mustering under three yards per carry across those two contests. With elite Cowboys run-blocking guard Tyler Smith (thumb) still out with an injury, Williams played well in Week 3 despite problems along the offensive line. Dallas will travel to Houston for their Week 4 game, though, and the Texans are one of the toughest defenses in the NFL. Williams' receiving role helps, though he doesn't get an impressive amount of volume through the air by any means. This makes him a boom-or-bust low-end RB1 -- he has the volume to avoid the low end of single-digit scoring outings, but not the pass-catching role to propel him to overall RB1 finishes in any given week. Still, Williams should be locked into starting lineups in all fantasy leagues for the Cowboys' next game.
Source: ESPN
Source: ESPN
George Pickens Has Work Cut Out For Him Against Strong Texans Secondary
Dallas Cowboys wide receiver George Pickens is fresh off his best game of the 2026 season, but it still feels like there's meat left on the bone for fantasy managers who drafted him in the second round of fantasy drafts. His eight catches for 82 yards against the Baltimore Ravens in Week 3 constituted his best game of the season, but he hasn't reached the end zone yet and ranks outside the top-30 fantasy football wide receivers through three games. It's been a far cry from his WR5 overall finish in 2025, in which he eclipsed 25 PPR fantasy points on five separate occasions. A tough matchup with the Houston Texans on the road lies ahead -- they have one of the best pass defense in the NFL in recent times. Pickens matches up well against all but the best cornerbacks in the NFL, and having wide receiver CeeDee Lamb to draw away coverage helps immensely, but he's just a mid-range WR2 with upside for this matchup. He should be started in all leagues anyway, as he's been targeted at a high enough rate that an explosion game feels imminent.
Source: ESPN
Source: ESPN
Dak Prescott To Face Toughest Test Yet In Week 4
Dallas Cowboys quarterback Dak Prescott will face the best defense in the NFL from a year ago in Week 4. The Cowboys will go on the road to take on the Houston Texans, who have one of the best pass-rushers in the NFL, one of its best cover cornerbacks, and a renowned defensive-minded head coach. Prescott hasn't faced the Texans since 2022, when they were nothing like they team they are today, so we don't have much precedent to go off of. But he's been productive so far this year, with seven passing touchdowns to just one interception. He hasn't fumbled yet either. Taking care of the football will be crucial, as the Texans were third in the NFL in 2025 with 29 turnovers forced. Prescott is a must-start in 2QB and superflex leagues, but there's reason for some trepidation in 1QB leagues, where he's a low-end QB1 due to the difficulty of the matchup.
Source: ESPN
Source: ESPN
Eli Raridon Questionable With Thigh Issue
New England Patriots tight end Eli Raridon (thigh) is questionable for this weekend's road outing with the Buffalo Bills. Raridon missed two days of practice and subsequently missed a loss to the Jaguars after injuring his thigh in a Week 2 home game with the Steelers. That the rookie could improve his participation to limited leading up to Sunday is a step in the right direction, but it would seem that he's not out of the woods just yet. If the 22-year-old is inactive again, teammates Cameron Latu and Tanner Arkin will shoulder the snap load alongside starter Hunter Henry. Raridon isn't quite on the radar yet for redraft leagues, but he's a tantalizing stash in dynasty formats because of his strong athletic profile and standing on the depth chart.
Source: New England Patriots
Source: New England Patriots
Tyrone Tracy Jr. Cleared to Play in Week 4
New York Giants running back Tyrone Tracy Jr. will head into Sunday's matchup against the Arizona Cardinals injury-free after a full practice Friday. The third-year back out of Purdue was bothered by a knee issue that forced him to miss Wednesday's practice. However, he upgraded his participation each of the next two days as the team preps for the visiting Cardinals. Following a subpar preseason performance, Tracy has fallen out of favor with the Giants' coaching staff, totaling three carries for 17 yards across four snaps. He appears to be a distant fourth option behind backfield mates Najee Harris, Cam Skattebo, and Devin Singletary, and can be safely avoided by fantasy managers in all formats.
Source: New York Giants
Source: New York Giants
CeeDee Lamb Still Elite WR1 Despite Tough Week 4 Matchup
Dallas Cowboys wide receiver CeeDee Lamb is back to full health after a long recovery from a high-ankle sprain he suffered early last season. The difference in production was immediately remarkable -- Lamb has 20 receptions for 309 yards and two touchdowns through three games. He's the WR3 overall in PPR fantasy leagues and has wrested the clear WR1 role away from his teammate, WR George Pickens. A tough matchup with the Houston Texans is looming, but Lamb is good enough that he can have big games against any defense. He's also re-established his elite connection with quarterback Dak Prescott. Lamb is moved all over the field, so he won't be exclusively playing on the outside against Derek Stingley Jr. every snap. Lamb's fantasy floor feels extremely safe. He should continue to live up to his first-round ADP in fantasy football, though his ceiling may not be at his career peak levels due to Pickens' presence.
Source: ESPN
Source: ESPN
Mike Evans to be Game-Time Decision in Week 4
San Francisco 49ers wide receiver Mike Evans (ribs) will be a game-time decision for the upcoming Week 4 matchup against the Denver Broncos, per Vic Tafur. Head coach Kyle Shanahan confirmed this news on Friday after Evans was listed as questionable to suit up. The veteran wideout is nursing a strained rib that he suffered last week. If active, there is some risk for fantasy managers with Evans not being completely healthy. Without Evans available, Deebo Samuel Sr., George Kittle, and Christian McCaffrey would be the focal points on offense. It's a tough matchup for Evans, and he's banged up, so he's probably a safe WR3, assuming he's active.
Source: Vic Tafur
Source: Vic Tafur
Keon Coleman is Considered Questionable for Week 4
Buffalo Bills wide receiver Keon Coleman (ankle) is listed as questionable on the team's official injury report ahead of the Week 4 matchup against the New England Patriots. Coleman missed Wednesday's practice before getting in back-to-back limited sessions to wrap up the week. It seems like he'll likely play through the issue, but fantasy managers will have a better idea soon. Coleman had a strong six-catch performance in Week 2, but he has been invisible outside of that. Fellow wideout DJ Moore (shoulder) is active, so Coleman will probably take a backseat to him this weekend.
Source: Buffalo Bills
Source: Buffalo Bills
Antonio Williams Could See Bigger Role in Week 4
Washington Commanders wide receiver Antonio Williams is hopeful to break out of his slump against the Indianapolis Colts this weekend. Williams was solid in the season opener when he hauled in four receptions for 64 yards and a touchdown. Since then, Williams has been quiet, but he has a chance to break out this weekend. Fellow wideout Terry McLaurin (hamstring) is currently listed as questionable to suit up for Sunday's game. He appears to have tweaked something during Friday's practice, so he won't have a ton of time to get ready for Sunday's game. If McLaurin is out, Williams could step into a larger role in the passing game, which might put him in flex territory for Week 4.
Source: Pro Football Reference
Source: Pro Football Reference
Rhamondre Stevenson is Losing Touches
New England Patriots running back Rhamondre Stevenson has seen his workload in the backfield take a hit in recent weeks. Stevenson carried the ball 18 times for 51 yards in the season opener. Since then, Stevenson has been limited to 13 carries for 65 yards across the last two games. Fellow back TreVeyon Henderson has been getting more involved with 24 carries since Week 2. It looks like the Patriots plan to split up the workload between the two of them going forward. It might be difficult for Stevenson to offer weekly value with Henderson taking half the carries. Fantasy managers can be hopeful for a bounce back performance, but the last two games haven't been pretty for Stevenson. We'll see what he is able to do against the Buffalo Bills in Week 4.
Source: Pro Football Reference
Source: Pro Football Reference
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