NFL DFS Picks for Week 4 - FanDuel Top Plays, Value Picks for Daily Fantasy Football Lineups (2025)

Dennis Clausen's FanDuel NFL DFS picks and lineup sleepers for the Week 4 Main Slate (2025). His top daily fantasy football lineups to target for FanDuel DFS contests.

Week 4 began with a Thursday night NFC West meeting between the Seattle Seahawks and Arizona Cardinals. Then, there is an early morning game on Sunday, with the Steelers and Vikings facing off in Ireland. While there are also two games on Monday night, there are still more than enough DFS options on Sunday.  

In this article, I will be providing you with my Week 4 daily fantasy football lineup picks for the 2025 NFL season. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel.

Be sure also to check out our weekly DraftKings DFS lineup picks from Jamie Calandro and plenty of other great NFL DFS articles and NFL DFS tools at RotoBaller to help you win big!

Week 4 FanDuel Quarterbacks - NFL DFS Lineup Picks

Caleb Williams – at Las Vegas Raiders ($7,500) 

As expected, Lamar Jackson and Josh Allen are the top fantasy quarterbacks after the first three weeks. Yet, few predicted that Williams would be sitting right behind them. The Bears are 1-2, but to be fair, the signal-caller has done his part.

Caleb Williams has embraced Ben Johnson's style and thriving in it 👀 pic.twitter.com/OEn2GNNp2a

— Bears on CHSN (@CHSN_Bears) September 24, 2025

Heading into the Week 4 meeting with the Raiders, he’s thrown for 715 yards, seven touchdowns, and one interception. His completion percentage has room for improvement, but he’s still certainly worth rostering for Sunday’s clash with Las Vegas.  

Drake Maye – vs. Carolina Panthers ($7,100) 

Maye didn’t have a quality inaugural year. He appeared in 13 games as a rookie, finishing with 2,276 yards, 15 touchdowns, and 10 interceptions. On the other hand, the 23-year-old has shown improvement in his second season in the National Football League. Although Maye has tossed only five touchdowns, he’s at least completed 72.6% of his attempts.

The Panthers secured a decisive win over the Atlanta Falcons in Week 3. With that said, Maye is certainly a better quarterback than Michael Penix Jr., so Carolina’s defense shouldn’t be nearly as dominant.  

Also Consider: Josh Allen ($9,000), Geno Smith ($7,200), Brock Purdy ($6,600) 

Week 4 FanDuel Running Backs - NFL DFS Lineup Picks

Omarion Hampton – at New York Giants ($7,000) 

Hampton didn’t have the best start to his rookie season. He had only 7.1 fantasy points versus the Chiefs in Week 1 before finishing with 3.0 in the Week 2 meeting with the Las Vegas Raiders. Week 3 was a different story, with the 2025 No. 22 overall pick amassing 70 yards and a touchdown off 19 attempts while catching six of his seven targets for 59 yards for 21.9 fantasy points.  

Omarion Hampton Week 3

- 79% snaps
- 19 carries, 70 yards, TD
- 31 routes, 7 targets, 6 catches, 59 yards
- 24.9 fantasy points

That is what you call a breakout performance

— Michael F. Florio (@MichaelFFlorio) September 21, 2025

Najee Harris was somewhat of a threat to steal touches, even though he didn’t get many snaps out of the gate. However, with Harris done for the year due to a torn Achilles, the door is open for Hampton to be even more involved moving forward. All things considered, DFS managers must keep him on the radar in Week 4 against the Giants, a team that has had a tough time stopping the run.  

Cam Skattebo – vs. LA Chargers ($5,400) 

Speaking of the Giants, New York is winless after the first three weeks of the season. As in previous years, the G-Men are looking for answers, especially on the offensive side of the ball. The team announced on Tuesday that Jaxson Dart will get the start in Sunday’s game against the Chargers. Not only that, but it appears Skattebo will be in line for more work. Tyrone Tracy Jr. dislocated his shoulder in Sunday evening’s loss to the Kansas City Chiefs.

In his absence, Skattebo stepped up to the task. He had 10 carries for 60 yards for an impressive 6.0 yards per carry. He also scored a touchdown while adding 61 yards off six receptions. Los Angeles has one of the best defenses in the National Football League, so it could be a rough debut for Dart, who may look to Skattebo often if he gets in trouble.

With Tracy anticipated to miss a few games, Skattebo has a chance to cement his place as the No. 1 back on the depth chart moving forward.  

Also Consider: Christian McCaffrey ($9,300), Bucky Irving ($7,300), Ashton Jeanty ($6,800) 

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Week 4 FanDuel Wide Receivers - NFL DFS Lineup Picks

Keenan Allen – at New York Giants ($6,500) 

Allen is coming off a relatively productive year with the Chicago Bears. The 33-year-old is now back with Justin Herbert and the Chargers, and he’s picked up right where he left off. He began the year by catching seven passes for 68 yards and a touchdown against the Kansas City Chiefs in Brazil.

Allen followed that up by combining for 12 receptions for 126 yards and two scores in Weeks 2 and 3. He’ll try to make it four-straight contests with a touchdown in Week 4 versus the New York Giants in a game that may not be as lopsided as projected.  

Chris Olave – at Buffalo Bills ($6,000) 

After battling concussions throughout his career, some looked past Olave in fantasy drafts ahead of the 2025 campaign. So far, things have gone well for the wideout. He currently is second at the position with 23 catches while leading the league in targets (37).

Although the Saints have a tough challenge ahead against the unbeaten Buffalo Bills on Sunday, Olave’s $6,000 rostering cost is too good to pass up, considering his level of involvement this season.  

Also Consider: Puka Nacua ($9,400), Nico Collins ($8,200), Jakobi Meyers ($6,100), Jauan Jennings ($5,900) 

Week 4 FanDuel Tight Ends - NFL DFS Lineup Picks

Dalton Kincaid – vs. New Orleans Saints ($5,600) 

Heading into last season, expectations were high for Kincaid. Unfortunately, things didn’t exactly work out, with the 25-year-old scoring only two touchdowns. He also missed three games due to a PCL sprain. As a result, his stock fell heading into the 2025 season. With that in mind, he has played better than projected through the first three weeks.

McDermott on Dalton Kincaid showing improvement this season:

"he put in the work"#billsmafia

— Jenna Cottrell (@JennaCottrell) September 24, 2025

Kincaid has caught 13 passes (16 targets) for 151 yards. He’s also found the end zone twice, matching his totals in 2024 and 2025, and it only took him three games to do it. Allen should continue to spread the ball around to different receivers moving ahead. While that makes Kincaid a somewhat risky DFS option in Week 4, his $5,600 rostering cost, along with a favorable matchup versus the New Orleans Saints, gives him plenty of upside.  

Also Consider: Brock Bowers ($6,700), Tyler Warren ($5,800), Hunter Henry ($5,500) 

More DFS Analysis and Lineup Picks