🖥 TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Lineup Picks (Week 10) - NFL DFS Advice

RotoBallers, welcome to Week 10 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 10 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 10!

 

DraftKings Quarterbacks - Week 10 DFS Picks

Matthew Stafford - DET vs CLE (DK $6,800)

Stafford is looking like one of the best options at quarterback this week, and coming off a big game. He played on Monday night, so his price wasn't adjusted for his performance last week. This is somewhat minor, but still and edge to be gained and we want to jump on it. Stafford has put up 300 yards or more in three straight games, and has seven touchdowns in his last four games. Really strong numbers from the highest paid quarterback. With his price and recent performance you could use him in either cash or GPPs, since he has a favorable match up. Speaking of his opponent, let's talk about the Browns! The Browns have the 28th DVOA against the pass, and simply cannot not stop the ball via the air. You want to find them every week, and target against them. Get exposure to them by either the quarterback or the receivers. The Browns are actually very good vs the run, so nearly all of the Lions offense will come from Stafford.

Ryan Fitzpatrick - TB vs NYJ (DK $4,900)

If you are looking for a cheap quarterback that has a solid match up, key in on Fitzpatrick this week. Not only is this a nice revenge game for him, going up against his former team, but the Jets have the 21st DVOA against the pass, and haven't looked strong on defense. For his price, he really only needs to put up 14.7 DraftKings points in order to reach 3x value, which is what you are looking for in cash games. Anything more than that, and will make a good tournament play. Stacking him with someone like DeSean Jackson, makes a good play since he has plenty of touchdown upside.

 

DraftKings Running Backs - Week 10 DFS Picks

LeSean McCoy - BUF vs. NO (DK $8,300)

Seems like few people are talking about McCoy this week, and might be due to the fact he had such a bad showing last Thursday night. If no one is going to be rostering him, he makes a great tournament play, since he has multi touchdown upside, along with seeing plenty of targets out of the backfield. Getting the full point PPR on DraftKings is huge for a running back, and will have plenty of chances to break the 100 yard bonus in either rushing or receiving. He is $400 cheaper than he was in the two previous weeks, and is at home against the Saints who have the 28th DVOA against the rush. The Saints defense has improved a good amount since the beginning of the season, but it was mainly their secondary. They are still weak vs the run, and with this game set to be cold with a bit of weather, the Bills should be running the ball plenty.

Carlos Hyde - SF vs NYG (DK $6,300)

Hyde is looking to be one of the stone locks this week, for multiple reasons, so let's dive in. First off, he is at home against the Giants, who have have the 28th DVOA overall, and the 26th DVOA against the rush. We all know how bad the Giants are, and they simply cannot stop really anyone on defense. They are bad against the run, bad against the pass, and most importantly, bad against running backs in the passing game. Hyde has six or more targets in four straight weeks, including nine or more in the last two. A running back getting that volume is huge, just as I mentioned with McCoy. Hyde has also seen 12 or more rushing attempts in four straight weeks. They are feeding him the ball in all aspects of the game, and with how bad the 49ers quarterback situation is, he should be in for a very busy day.

 

DraftKings Wide Receivers - Week 10 DFS Picks

Cooper Kupp - LAR vs HOU (DK $4,600)

Kupp was a bit unlucky last week with the Rams putting up so many points, yet barley seeing the ball at all. He ended with three catches on five targets for 54 yards and no touchdowns. Yes, Jared Goff, only completed 14 passes, so Kupp didn't have a ton of chances. But this week Kupp has a good match up against the Texans, who have the 16th DVOA against the pass, and the 30th DVOA against WR2. With the inconsistency Sammy Watkins has been showing, Kupp is seeing the second most targets on the team, with 47 targets in the first nine weeks. The Texans defense really isn't as good as people think, and attacking them in this spot is a good call.

A.J. Green - CIN @ TEN (DK $7,700)

Green is simply too cheap this week. A player with his skill, and his potential ceiling of points should not be under $8K. Whenever a player is in a spot like this, you want to jump all over him, since he price won't stay this low. Yes, his ownership could get a bit out of hand in GPPs, but having legit two touchdown upside for under $8K is fantastic. Last week he was ejected from the game for a fight, so his stats are a bit out of wack. Without last game, he has 46 targets in the prior five, and four touchdowns over that span. Pretty straight forward spot, don't over think it because of last week.

 

DraftKings Tight End - Week 10 DFS Pick

Kyle Rudolph - MIN @ WAS (DK $4,600)

Rudolph is one of the more consistent tight ends in the league, and is viable for any format this week. He has seven or more targets in four straight weeks, and has two touchdowns over that span. He has become one of the favorite targets for backup quarterback Case Keenum, and gets the volume any DFS player loves. Rudolph also has a very favorable match up, since he is up against the Redskins, who have the 29th DVOA against tight ends. Really like him in this spot, just getting up to his price may be hard, if you are trying to roster two top end running backs.

 

DraftKings Defense - Week 10 DFS Pick

Chicago Bears vs Green Bay Packers (DK $3,000)

Bears are going to be one of the more popular options at defense this week, and it comes with good reason. They are up against at Brett Hundley led Packers team, who as we all saw on Monday night, are very bad. The Packers are having a ton of trouble moving the ball offensively, and picking on them in fantasy is a good call. The Bears have 14 sacks over the past four weeks, along with four interceptions. They are putting pressure on the quarterback, and forcing bad decisions. They aren't too expensive, and should have a good floor of points.

 

More Week 10 DFS Analysis

 

NFL DFS Premium Tools & Research

Get a free trial of our powerful NFL Premium Tools. Our famous Matchup Rating Projections, DFS Cheat Sheets, and NFL Lineup Optimizer/Generator.

Win more. Try the most advanced lineup optimizer in daily fantasy football.

Sign Up Now!




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Pete Fairbanks

Marlins Agree on One-Year Deal
Josh Johnson

to Start at QB on Thursday Against Dallas
Brooks Koepka

Leaving LIV Golf
Davante Adams

Could Sit Out Final Two Regular-Season Games
Brock Bowers

Placed on Injured Reserve Due to Lingering Knee Injury
Amon-Ra St. Brown

Expected to Play on Christmas Day Against the Vikings
Connor McDavid

Finishes Battle of Alberta With Five Assists
Karel Vejmelka

Battling Upper-Body Injury
Alexandre Texier

Suffers Upper-Body Injury Against Bruins
Alexander Nikishin

Dealing With Apparent Ankle Injury
Denver Barkey

Exits Early Tuesday
Travis Sanheim

Pulled by Concussion Spotter Tuesday
Cam Whitmore

Out Indefinitely With Deep Vein Thrombosis
Corey Kispert

Lasts for 13 Minutes in Comeback Game
Jaxson Hayes

Makes Early Exit Versus Suns
Gary Trent Jr.

Limited to Five Minutes Tuesday
Matas Buzelis

Exits With Leg Injury Tuesday
Keegan Murray

Sustains Calf Injury Tuesday
Cameron Johnson

Scheduled for MRI After Hurting Right Knee
Chet Holmgren

Suffers Facial Injury Tuesday
Caris LeVert

Upgraded to Available Tuesday
Ron Holland II

Remains Out Against Kings
Robert Williams III

Sits Out Tuesday's Game
Jonathan Isaac

Active Tuesday Night
Javon Small

Returns to Grizzlies Lineup Tuesday
Tristan da Silva

Remains Sidelined Against Portland
Goga Bitadze

Out Against Portland
Vince Williams Jr.

Misses Third Consecutive Game
Cedric Coward

Unavailable on Tuesday Night
Aaron Wiggins

Will Play Against Spurs
Ryan O'Hearn

Pirates Agree on Two-Year Deal
Grayson Allen

Absent for Third Consecutive Game
Zach LaVine

to Miss at Least One More Week
Victor Wembanyama

Ready to Take on Thunder
DK Metcalf

has Two-Game Suspension Upheld
Philip Rivers

to Remain the Starter in Week 17
George Kittle

Dealing With Mid-to-Low Ankle Sprain
Viktor Arvidsson

a Game-Time Decision Tuesday
Ryan Leonard

Available Tuesday
Tom Wilson

in Danger of Missing First Game of the Season
Phillip Danault

Makes Second Canadiens Debut Tuesday
Collin Graf

Available Against Golden Knights
Jack Eichel

Misses Fourth Straight Game
Vince Dunn

Won't Play Tuesday
Deshaun Watson

Will Not be Activated Off PUP List, 2025 Season is Over
J.J. McCarthy

Ruled Out for Week 17
Rome Odunze

Expected to Return This Season
Christian McCaffrey

Another Monster Game for Christian McCaffrey in Week 16
Brock Purdy

Throws for Five Touchdowns in Week 16
TreVeyon Henderson

in Concussion Protocol, Week 17 Status Unclear
George Kittle

Week 17 Availability in Question?
CFB

Jeff Brohm, Eli Drinkwitz "Names of Interest" for Michigan Head Coach
Timothy Liljegren

to Miss Second Straight Game Tuesday
Will Smith

Out Week-to-Week
Jaccob Slavin

Placed on Injured Reserve, Out Week-to-Week
Seth Jarvis

Considered Week-to-Week
Darren Raddysh

Totals Three Points in Monday's Win
Mason Marchment

Scores Twice Monday
Vince Dunn

Injured in Monday's Win
Rashee Rice

Still in Concussion Protocol, Estimated as Non-Participant on Monday
J.J. McCarthy

Listed as DNP on Monday Ahead of Week 17
Ilya Sorokin

to Miss Tuesday's Game
DK Metcalf

Suspended for Two Games Following Confrontation with Fan
CFB

Byrum Brown Entering Transfer Portal
CFB

Bobby Petrino Joining Bill Belichick as North Carolina's Offensive Coordinator
TreVeyon Henderson

Exits Week 16 Victory with Head Injury
Lamar Jackson

Questionable to Return in Week 16 with Back Injury
Willson Contreras

Shipped to the Red Sox
Quinshon Judkins

Done for the Season with Broken Leg
Nick Chubb

Officially Active Against Raiders in Week 16
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
Shane Baz

Orioles Acquire Shane Baz From the Rays
CFB

Darian Mensah Returning to Duke Next Season
CFB

Josh Hoover Linked to Indiana in Transfer Portal
CFB

Arch Manning Agrees to Reduced Compensation for 2026 Season
Michael King

Padres Bring Michael King Back on Three-Year Deal
Logan Webb

Will Pitch for Team USA in World Baseball Classic
Tarik Skubal

Joins Team USA for World Baseball Classic
CFB

Will Muschamp Becoming Next Texas Defensive Coordinator

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP