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DraftKings Lineup Picks (Week 15) - NFL DFS Advice

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 15 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 14!

 

DraftKings Quarterbacks - Week 15 DFS Picks

Matt Ryan - ATL @ TB (DK - $6,300)

Ryan is coming off a very rough three interception game, but now has a very favorable match up in his favor. He is at division rival Tampa Bay, who has the 31st DVOA against the pass, who when he played them earlier this season, he put up over 300 yards and one touchdown. This is a level of production that he should be able to match, considering the Falcons have an implied team total of 27 points, which is third highest on the slate. This game is on Monday night, so you will have to have to play on one of the expanded slates to get to him. Given the match up, he has multi-touchdown upside and a good play for GPPs.

Derek Carr - OAK vs DAL (DK - $5,700)

Carr has scored 14.5 or more DraftKings points in six of his last seven games, and is facing a weak defensive opponent. At his price, he really only needs about 16 DK points in order to reach 3x value for cash games. He is up against the Cowboys, who have the 22nd DVOA against the pass, and have shown they are very weak in the secondary. Carr will be without Amari Cooper, so pairing him with Michael Crabtree is a good idea for either format. Carr along with the Raiders haven't been consistent this season, so some DFS player might be afraid to roster him, opening the chance for lower ownership.

 

DraftKings Running Backs - Week 15 DFS Picks

Dion Lewis - RB, NE @ PIT (DK - $5,400)

Lewis has double digit rushing attempts in seven of his last last eight games, along with 11 targets in his lat four games. This game vs the Steelers has an over-under of 53 points, making it the highest of the slate, so you will want some exposure to this game. He isn't too expensive, and with the snaps he is seeing, he can pay off his salary quickly. The Steelers have the 29th DVOA against running backs in the passing game, which makes this a fantastic match up, considering his PPR value out of the backfield.

LeSean McCoy - RB, BUF vs MIA (DK - $8,400)

McCoy is in line to see plenty of work this week considering the fact the Bills are in a tough spot at quarterback. Seemingly for the past month, the Bills have a rotating cast at quarterbacks, because of injuries. McCoy had 32 carries last week, which is super high, but that was mainly due to the weather. He won't see that type of volume every week, but with Tyrod Taylor on the injury report, he could see close to it. McCoy is up against the Dolphins who have the 14th DVOA against the run.

 

DraftKings Wide Receivers - Week 15 DFS Picks

Michael Thomas - WR, NO vs NYJ (DK - $7,400)

Thomas is coming off his best game of the season, and is in an even better spot this week. He is up against the Jets who have the 27th DVOA against pass, and the 30th DVOA against WR1. This is a prime spot for him, and has massive PPR value. He has seen eight or more targets in 12 of 13 games this season, and should be able to replicate that production. He is almost a lock for 12 or more DraftKings points, and should be good for any format this week.

Keelan Cole - WR, JAX vs HOU (DK - $3,700)

Cole has 27 targets over his last five games, and for his price, he offers a ton of savings. He is up against the Texans who have the 18th DVOA against the pass, and the 27th DVOA against WR2. Cole also has touchdowns in two straight weeks, and is in a good spot to repeat that. This game may not have the highest over-under, but Cole offers some much needed savings on this full slate.

 

DraftKings Tight End - Week 15 DFS Pick

Evan Engram - TE, NYG vs PHI (DK - $5,600)

Engram has seen six or more targets in 11 of his 13 games this season, and has become the favorite receiver of Eli Manning. He is up against the Eagles, who have the 19th DVOA against tight ends, putting him in a good spot to succeed this week. If you don't want to spend all the way up to get Gronk or Kelce, he makes a good option in the middle. Good for any format this week, as he has PPR value, along with touchdown upside.

 

DraftKings Defense - Week 15 DFS Pick

Minnesota Vikings vs Cincinnati Bengals - (DK - $3,500)

The Vikings are averaging three more DraftKings points at home this season, and are now up against a Bengals team who has been very inconsistent on offense. They have seven sacks over their past four games, and two interceptions over that span. They are one of the more expensive options on the slate, so getting up to them in price price can be hard in cash games, but they are a great tournament option.

 

More Week 15 DFS Analysis

 




REAL-TIME FANTASY NEWS

Indianapolis Colts

Colts Officially Sign Philip Rivers
CFB

Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
DK Metcalf

"Moving in the Right Direction" for Week 15
CFB

Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
Riley Leonard

Diagnosed With Grade 1 PCL Sprain
Jamison Battle

Unlikely To Suit Up Against Knicks
Derik Queen

Posts Massive Triple-Double In Loss To Spurs
Jacob Toppin

Out For Season After Shoulder Surgery
Ben Sheppard

Out At Least 10 Days With Calf Strain
Miles McBride

Ruled Out With Ankle Sprain Against Raptors
CFB

Ole Miss Hiring John David Baker as Offensive Coordinator
Victor Wembanyama

Travels For NBA Cup Clash Against Lakers
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
John Gibson

Secures Third Consecutive Win With Shutout
Nazem Kadri

Bags Three Points as Flames Offense Explodes
Joel Eriksson Ek

Ends Dry Spell With Three-Point Effort
Dennis Hildeby

Records First Career Shutout
Dakota Mermis

to be Evaluated Tuesday
Jacob Middleton

Hurt in Monday's Win
Mats Zuccarello

Exits Early Monday
Jamal Shead

Uncertain for Tuesday
Dru Smith

Questionable to Play Tuesday
Pelle Larsson

Listed as Probable for Tuesday
Davion Mitchell

Expected Back Tuesday
Tyler Herro

Likely to Return for Cup Clash Against Magic
RJ Barrett

to Miss at Least One More Week
Karl-Anthony Towns

Iffy for Tuesday
A.J. Brown

Continues Dominant Stretch With 100 Yards in Monday Night Loss
Saquon Barkley

Rips Off Long Touchdown Run in Monday Night Loss
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
Riley Leonard

"Week-to-Week" With Strained Knee
NFL

Patriots-Ravens Week 16 Game Flexed to Sunday Night Football
Omarion Hampton

Making his Return on Monday Night
CFB

Heisman Trophy Finalists Announced on Monday
Justin Herbert

Officially Active Against Eagles
Indianapolis Colts

Colts Bringing Philip Rivers in for a Workout
Justin Herbert

Expected to Start on Monday Night
Trey Benson

Cardinals Could Hold Trey Benson Out Another Week
Keegan Murray

Available on Monday
Anthony Edwards

Set to Suit Up Monday
Jack Roslovic

Not Close to Returning
Dennis Schröder

Dennis Schroder Sidelined Again on Monday
Jake Walman

to Miss at Least Two More Weeks
Berkly Catton

Out Week-to-Week
Franz Wagner

Likely to Miss 2-4 Weeks
Nils Hoglander

Set for Season Debut Monday
Elias Pettersson

Misses Second Straight Game
Logan Cooley

Out Indefinitely
Brayden Point

Nikita Kucherov, Brayden Point Back for Lightning Monday
CFB

Anthony Hill Jr. Declaring for 2026 NFL Draft
CFB

Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Trey Hendrickson

Set for Core-Muscle Surgery, Expected to Miss Around Six Weeks
Drake London

Considered Day-to-Day Going into Thursday Night
Jayden Daniels

No Long-Term Concerns for Jayden Daniels
Zach Ertz

MRI Confirms Season-Ending Torn ACL for Zach Ertz
Tee Higgins

Back in the Concussion Protocol
Riley Leonard

Week 15 Status Uncertain Due to Knee Injury
Mike Evans

Could Return on Thursday Night
De'Von Achane

May Require Rest This Week
Daniel Jones

' Season Over With Torn Achilles
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
CFB

Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Jordan Poole

Remains Sidelined on Monday
Merab Dvalishvili

Drops A Decision At UFC 323
Herbert Jones

Tagged as Questionable Against Spurs
Petr Yan

Reclaims Bantamweight Title
Stephon Castle

has a Chance to Return on Monday
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Dillon Brooks

Iffy for Monday Night
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
Jan Blachowicz

And Bogdan Guskov Fight To Majority Draw
CFB

Texas RB CJ Baxter Entering Transfer Portal
Mark Stone

Records Two Assists in Sunday's Win
Carter Hart

Defeats Rangers Sunday
Cutter Gauthier

Delivers Two Assists Sunday
Leo Carlsson

Nets Two Goals in Blowout Win
Logan Thompson

Posts First Shutout of the Season
Brayden Schenn

Leads Blues to Victory Sunday
Macklin Celebrini

Bags Three Points in Impressive Road Victory
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte
Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber
CFB

Mississippi State, Rice Accept Bowl Bids as 5-7 Teams
CFB

Auburn, Florida State, Baylor Among Teams to Decline Bowl Bids
CFB

Rob Aurich Set to Become Nebraska's Defensive Coordinator
CFB

Notre Dame Opting Out of Postseason Amid College Football Playoff Exclusion
CFB

Kendal Briles a Candidate for South Carolina Offensive Coordinator Job
CFB

James Madison Playoff-Bound After Duke Wins ACC Title?
CFB

Notre Dame, Miami, Alabama on College Football Playoff Bubble
CFB

Brent Pry Could Return to Virginia Tech as Defensive Coordinator
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Harry Ford

Traded to the Nationals
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Brandon Moreno

Searches For His Third Win In A Row
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal

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WR
TE
K
DEF
RANKINGS
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1B
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3B
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