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Buffalo Bills running back James Cook posted another huge game in Week 4 in his team's 31-19 victory over the New Orleans Saints. Cook recorded 117 yards and a touchdown on 22 carries and added three catches for 18 yards for good measure as well. The 26-year-old has now logged 401 rushing yards and five touchdowns on 75 carries and 12 receptions for 89 yards through his first four games of 2025. He dominated backfield touches in Week 4, earning 22 out of 24 rush attempts by running backs for Buffalo against New Orleans. As long as he's healthy, Cook is a must-start fantasy running back.--Will Brady
Source: ESPN.com
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REAL-TIME FANTASY NEWS

Max Muncy

Expected to be Ready for Game 1 of Wild-Card Series
Amon-Ra St. Brown

Records Two More Touchdowns in Week 4
Drake London

Breaks Out With Monster Game in Week 4
Bo Bichette

Without a Timeline, Unlikely to Return in Postseason?
Justice Hill

Carries Ravens Offense With Two Scores in Otherwise Gloomy Loss
Puka Nacua

Strengthens Grasp on WR1 Title with Explosive Game Sunday
Ricky Pearsall

Feels Pain and Instability in Knee Before Exiting
Ashton Jeanty

Explodes for Three Touchdowns in Loss
Drake Maye

Flashy in Week 4 Win Over Tough Opponent
Lamar Jackson

Questionable to Return with Hamstring Injury
Bucky Irving

Totals 165 Yards in Loss to Eagles
Woody Marks

Breaks Out, Scores Twice in Win
Jared McCann

on Track to Be Available for Opening Night
Brandon Montour

Expected to be Available for Season Opener
Mason Marchment

Returns to Practice
Evan Rodrigues

Exits Practice Early Sunday
Anthony Stolarz

Signs Four-Year Extension With Maple Leafs
Cam Fowler

Blues Extend Cam Fowler for Three Years
Omarion Hampton

Explodes in First Full Game with Expanded Role
Bijan Robinson

Explodes for 181 Yards in Sunday's Win
Malik Nabers

Will Undergo MRI Monday to Confirm Torn ACL Diagnosis
Isaiah Likely

Active Sunday for Season Debut
Ricky Pearsall

Active Versus Jaguars Sunday
Darnell Mooney

Won't Return Against Commanders Sunday
D'Andre Swift

Suiting Up for Week 4 Against Las Vegas
Colston Loveland

Won't Play in Week 4 Against Raiders
Joe Alt

Done for Week 4, Feared to Have High-Ankle Sprain
Darnell Mooney

Questionable to Return in Week 4
Malik Nabers

Believed to Have Suffered Torn ACL in Week 4
Golden State Warriors

Al Horford Agrees to Join the Warriors
Noah Gragson

May Be A Sneaky DFS Option For Kansas Lineups
Todd Gilliland

Is A Quality Value Option for Kansas Lineups
Kyle Larson

the Favorite to Win at Kansas
Ryan Blaney

the Chalk DFS Play at Kansas
Denny Hamlin

Has Struggled at 1.5-Mile Tracks This Season
William Byron

a Solid DFS Pivot at Kansas
Alex Bowman

Will Alex Bowman's Top-10 Streak at Kansas Continue?
Ryan Preece

Should Have Speed at Kansas
Christopher Bell

Has Been Consistent at Kansas Despite Rarely Contending to Win
Joey Logano

Miserable Qualifying Result Makes Joey Logano a Top DFS Contender
Chase Elliott

Likely to Make Round of 8, but Has Hardly Been Inspiring
Austin Cindric

Unlikely to Advance in NASCAR Playoffs
Ty Gibbs

Likely to Finish Much Worse Than He Starts
Josh Berry

Might Be Let Down by Penske's Slow Cars This Weekend
Austin Dillon

Qualifies Too Well for Place-Differential Points at Kansas
Kyle Busch

Despite Poor Qualifying Result, Stay Away from Kyle Busch
Shane Van Gisbergen

Not Worth Starting at Kansas
Ricky Stenhouse Jr

. Arguably Becoming NASCAR's Most Invisible Driver
Michael McDowell

th Most Mediocre on Intermediate Tracks
Daniel Suarez

Lame-Duck Daniel Suarez has Miserable Kansas Record
Ranger Suárez

Ranger Suarez Exits Early With Thigh Contusion in Loss
Trea Turner

to Return on Sunday
Ramón Laureano

Ramon Laureano Lands on 10-Day Injured List
Georges Niang

Set to Miss at Least Two Weeks
Jared McCain

to Miss 4-6 Weeks
Gradey Dick

Cleared for Training Camp
Brandon Ingram

Good to Go for Training Camp
Jalen Johnson

Fully Healthy for Training Camp
JJ Peterka

Nursing Undisclosed Injury
Kirill Kaprizov

Dealing With Eye Infection
Mason McTavish

Agrees to Six-Year Deal With Ducks
Kaapo Kakko

to Miss Six Weeks With Broken Hand
Nicolas Roy

Makes Maple Leafs Debut Saturday
Max Domi

Returns to Action Saturday
Brett Baty

Lands on 10-Day Injured List With Oblique Strain
Cade Horton

Goes on 15-Day Injured List With Fractured Rib
Jazz Chisholm Jr.

Exits After Hit by Pitch, X-Rays Negative
Josh Naylor

Suffering from "Minor Groin Tightness"
Jake Walman

Considered Day-to-Day
Jimmy Snuggerud

Avoids Serious Injury
Ethan Bear

Injured Against Devils
Jesperi Kotkaniemi

Injured on Friday
Victor Hedman

Exits Preseason Game Early
Aleksander Barkov

to Miss 7-9 Months
Pete Crow-Armstrong

Locks Up 30-30 Season
Giancarlo Stanton

Crushes Two Homers in Five-RBI Night
Josh Naylor

Exits With Apparent Injury on Friday
Brett Baty

May Have Season-Ending Oblique Injury
Yordan Alvarez

Done for Regular Season
Max Muncy

Absent Due to Leg Injury
Brandon Clarke

Bad News Continues: Grizzlies Lose Brandon Clarke to Knee Surgery
Zach Edey

Expected Back in December After Ankle Surgery
Jaren Jackson Jr.

Grizzlies Star Jaren Jackson Jr. To Miss Start of Season
Trevor Megill

Likely to Return on Sunday
Fernando Tatis Jr.

Back in Padres Lineup on Friday
CFB

Caden Durham Doubtful for Saturday at Mississippi
Connor Ingram

Clears Waivers
Mattias Samuelsson

Battling Upper-Body Injury
Alex Tuch

Ready for Action on Saturday
Trea Turner

Could Return on Sunday
Jackson Holliday

Back in Action on Friday
Dominick Reyes

Looks For His Fourth Consecutive Win
Carlos Ulberg

Set For UFC Perth Main Event
Ivan Erslan

Looks For His First UFC Win
Jimmy Crute

A Favorite At UFC Perth
Jack Jenkins

Aims To Get Back In The Win Column
Ramon Taveras

An Underdog At UFC Perth
Neil Magny

Looks To Win Back-To-Back Fights
Jake Matthews

Looks To Extend His Win Streak
Scoot Henderson

Hamstring Tear Will Keep him Out for Up to Two Months
Louie Sutherland

Set For His UFC Debut
Jonathan Aranda

Activated From Injured List on Friday
Justin Tafa

Looks To Get Back In The Win Column
Charlie Campbell

Looks To Remain Undefeated In The UFC
Tom Nolan

Set To Open Up UFC Perth Main Card
Andre Drummond

Says He's at 100 Percent
Paul George

May Miss Part of Training Camp
LeBron James

Lakers Would Love for LeBron James to Retire in LA
Joel Embiid

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Kyle Tucker

Returning on Friday
Walker Kessler

Jazz Discontinue Extension Talks Ahead of Season
Indiana Pacers

Pacers Decide Against Signing Monte Morris
Los Angeles Lakers

Lakers Sign JJ Redick to Extension
Charlotte Hornets

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Bilal Coulibaly

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Alexandre Sarr

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Viktor Hovland

Representing Team Europe at the Ryder Cup
Tommy Fleetwood

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CFB

Horatio Fields to Undergo Surgery on Broken Foot
CFB

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CFB

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