NFL DFS Picks for Week 4 Monday Night Football - FanDuel, DraftKings Top Plays, Value Picks for Daily Fantasy Football Lineups (2025)

September 29, 2025

Koby's top NFL DFS picks for Week 4 MNF (2025) DraftKings and FanDuel lineup sleepers for the Monday night football slate. His top FD and DK plays and value picks to target for DFS lineups.

Welcome Back, RotoBallers! We had a great SNF, and now we move on to a two-game MNF slate. I'm still not sure how I feel about these two game Monday night slates, but hopefully we can make some cash for the upcoming TNF game and some playoff baseball!

On this slate, it'll be similar to your normal DFS slate rather than the typical showdowns that I have been writing up. In the first game, we have the New York Jets traveling to Miami to take on the Dolphins. Then we have the Cincinnati Bengals traveling to Denver to take on the Broncos!

 In this article, I will be providing you with my Week 4 MNF daily fantasy football lineup picks for the 2025 NFL season. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure also to check out our weekly NFL DFS articles and NFL DFS tools to help you win big!

MNF Quarterbacks - NFL DFS Lineup Picks

Bo Nix vs. CIN ($6K DK/$7.5K FD) 

I worry about taking someone coming off a concussion, and I do think Justin Fields is a good play against the Dolphins. I'm just unsure how well he plays with an injury that has shown to have lingering effects. That being said, I'm going to go with Nix here against a Bengals defense that was just utterly slaughtered by the Vikings last week. With Carson Wentz, too. The Bengals had no answer for the Vikings' offense, and I think they will struggle again against Nix and the Broncos.

The Broncos have had him throwing the ball quite a bit, 25+ a game, and he's been running the ball quite a bit as well. The Bengals haven't played against a dual-threat QB this season, so we don't know how well they will do against one, but I think it adds just another thing the defense has to worry about.

Also Consider: Justin Fields ($5.5K DK/$7.6K FD)

MNF Running Backs - NFL DFS Lineup Picks

De'Von Achane vs. NYJ ($7K DK/$8K FD) 

Achane has been the lone bright spot for this Dolphins offense, and now he is going up against the Jets, who gave up decent-sized games to Bucky Irving and James Cook. Achane has been huge in the passing game this season with 18 receptions on the season already.

The Dolphins have been playing from behind in all three weeks this season, and I don't necessarily see them doing that here against the Jets. But even if they get ahead, Achane will see quite a few carries in the run game as well. Achane is the best RB option on this slate.

J.K. Dobbins vs. CIN ($5.8K DK/6.7K FD) 

Dobbins has been a bit of a surprise this season. I think a lot of people, including myself, thought RJ Harvey was going to take on a bigger role. Dobbins has shown why he should be the lead back. He has 60+ yards on 11+ attempts with a touchdown in all three games this season. He hasn't been active in the receiving, which I think hurts him a bit, but he is getting his fair share of carries, and the Broncos should be leading the whole game.

J.K. Dobbins's 5.41 yards/carry this year is the 4th best in the NFL. pic.twitter.com/sHhPWVjIye

— Zac Stevens (@ZacStevensDNVR) September 27, 2025

The Bengals' defense has been awful against RBs this year, too. They have given up the second-most fantasy points to opposing RBs this season; only the Baltimore Ravens have given up more this season. Dobbins is in a solid spot here and is the cheapest of the RB1s on this slate.

Also Consider: Breece Hall ($5.7K DK/$7K FD)

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MNF Wide Receivers - NFL DFS Lineup Picks

Garrett Wilson at MIA ($6.2K DK/$7.3K FD) 

This Jets WR core might be one of the worst in the league, but at least they have Wilson, who looks like the only one they will throw to. Fields tends to use his legs quite a bit, which hurts Wilson a bit and shows why he had such an explosive game with Tyrod Taylor last week. Wilson has played in 94% of snaps or more this season, logging every snap played in Weeks 1 and 3.

.@GarrettWilson_V became the 14th player in franchise history to reach 300 career receptions pic.twitter.com/ujh1IcZeSm

— New York Jets (@nyjets) September 23, 2025

Wilson will likely line up against Jack Jones with an injured secondary for the Dolphins. Jones has given up .43 fantasy points per route run this season. Wilson has garnered a 39% reception share on the season and is averaging 10 targets a game. Wilson should be in line for a big game, as long as Fields gets him the ball.

Jaylen Waddle vs. NYJ ($5.5K DK/$5.8K FD) 

We are getting Tyreek Hill numbers for nearly 2k cheaper on FD and a grand cheaper on DK. Hill has been targeted more times this season, but Waddle has become one of Tua Tagovailoa's top guys in the endzone. The last two weeks, he has had double-digit fantasy points and has caught 10 of his 12 targets.

I like the discount we are getting on Waddle here, with Sauce Gardner likely on Hill. It is Brandon Stephens we should be getting on Waddle. Stephens has given up .26 fantasy points per route run this season. Tyreek will likely still get his, but with Waddle being so much cheaper, I'll take him to spend up elsewhere.

Also Consider: Courtland Sutton ($6.1K DK/$7.1K FD), Ja'Marr Chase ($8K DK/$9.3K FD), Troy Franklin($4.1K DK/$5.5K FD)

MNF Tight Ends - NFL DFS Lineup Picks

Evan Engram – vs. CIN ($3.7K DK/$4.9K FD) 

The TE position is a nightmare to choose from; you could even recommend just completely punting the position if you need the salary because of how poor the options are. Engram grades out probably the best. The Bengals' defense has struggled against opposing TEs, giving up the fourth most this season. Engram was able to practice fully after missing Week 3 and should be good to go for this game. Engram is in line for a big game here; he just needs Nix to get him the targets he needs.

As for other options, Darren Waller could be a sneaky play. My only concern is that I'm unsure how many snaps he will see, given it's his first action since 2023. Noah Fant is out, which should put Mike Gesicki in line for a bigger role in the Bengals' offense as well, but will Jake Browning be able to get it to him...

Also Consider: Darren Waller ($3.5K DK/$4.8K FD)

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