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Thursday Night Football Start ‘Em Sit ‘Em - Rams vs. 49ers

Kyren Williams - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Must-Start: Kyren Williams, RB - Los Angeles Rams

Kyren Williams was firmly back in bell-cow status after conceding about a third of the snaps to Blake Corum in Week 13. Williams played 83% of snaps against the Buffalo Bills and touched the ball 31 times. Even against a tough San Francisco rush defense, that kind of volume is a must in fantasy lineups for the playoffs. Williams is now the RB8 on the season.

Cooper Kupp - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Must-Start: Cooper Kupp, WR - Los Angeles Rams

Let’s put it this way. Among the 28 targets thrown to pass-catchers last week against Buffalo, Cooper Kupp and the guy next on this list saw 22 of them. Kupp had eight targets, which went for five catches, 92 yards, and a touchdown. Despite missing 4.5 weeks with an injury, Kupp is still WR5 in fantasy points per game with almost 15 half-PPR points each time he takes the field.

Puka Nacua - Fantasy Football Rankings, Draft Sleepers, Waiver Wire Pickups

Must-Start: Puka Nacua, WR - Los Angeles Rams

Only Ja’Marr Chase has more fantasy points per game over the last four weeks than Puka Nacua. He went wild last week with 14 targets, 12 catches, 162 yards, and two total touchdowns. That is now five straight games with at least 98 yards or a touchdown for Nacua.

Jauan Jennings - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Must-Start: Jauan Jennings, WR - San Francisco 49ers

Jauan Jennings now leads all players on San Francisco in targets, and it isn’t especially close. Jennings has 42 targets over the last five weeks and he has been simply dominant as the 49ers WR1 in the five weeks since the San Francisco bye week. In that span, Jennings is tied with Terry McLaurin as the 12th-best wide receiver in fantasy football.

Must-Start: George Kittle, TE - San Francisco 49ers

In the most volatile position in the league this season, George Kittle has been a rock and someone you could rely on every week except the two weeks he missed with injury. He is the TE1 on the season with 14.2 fantasy points per game, almost two full points more than Brock Bowers at No. 2. The Rams are a bottom-10 defense against tight ends this season and Kittle has not yet been able to take advantage since he missed the first Rams game while hurt.

Matthew Stafford - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Solid Start: Matthew Stafford, QB - Los Angeles Rams

Over the last four weeks, Matthew Stafford has been the QB10 in fantasy scoring. It aligns, of course, with the good health of both Cooper Kupp and Puka Nacua, who both missed time early in the season. San Francisco is middle of the pack in terms of quarterback fantasy scoring allowed, but it is the second-best team in the league in preventing passing yards from quarterbacks (only the Titans have been better). For that reason only, Stafford is merely a good start instead of a must-start.

Brock Purdy - Fantasy Football Rankings, NFL injuries, DFS Picks

Solid Start: Brock Purdy, QB - San Francisco 49ers

In that same four-week span, Brock Purdy is QB27. He has two games with fantasy points over 19, one with a score of 2.2, and one game missed with an injury. On the season, he is QB9 thanks to a stretch where he scored at least 20 fantasy points in four straight games. In his last matchup with L.A., Purdy threw for three touchdowns and put up 25.8 fantasy points.

Patrick Taylor Jr. - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Solid Start: Patrick Taylor, RB - San Francisco 49ers

If Isaac Guerendo misses this game with his foot sprain, Patrick Taylor Jr. would be the next man up, meaning he would officially be the fifth man up at running back for the 49ers. With all of the other running backs hurt, Taylor has had very little time to practice with the starters, much less play. But in limited time last week, he rushed seven times for 25 yards and a touchdown.

While the Rams have done a good job limiting rushing touchdowns to running backs this season (only nine allowed), they do give up the eighth-most rushing yards on the season.

Demarcus Robinson - Fantasy Football Rankings, Waiver Wire Pickups, Draft Sleepers

Consider Sitting: Demarcus Robinson, WR - Los Angeles Rams

Demarcus Robinson was DNP for two straight days to start the week due to his shoulder injury. It does not look good for his availability in this one, and even if he were to suit up, he could be limited in his snaps or yanked from the game if he aggravates the injury. Robinson has been playing a healthy amount of snaps, but this spot is not the place to roll the dice in the first game of the first round of the fantasy playoffs.

Tutu Atwell - Fantasy Football Rankings, Draft Sleepers, Waiver Wire Pickups

Consider Sitting: Tutu Atwell, WR - Los Angeles Rams

If Demarcus Robinson and Jordan Whittington miss this game on Thursday, there is a chance Tutu Atwell could get a full-time role as the Rams WR3. He is firmly on the radar in deeper leagues for a flex position if that happens, but he is WR74 on the season and hasn’t sniffed 10 fantasy points in a game since Week 4.

Colby Parkinson - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Consider Sitting: Tyler Higbee and Colby Parkinson, TEs - Los Angeles Rams

Colby Parkinson has been running as the TE1 for a few weeks but has exactly one catch in each of his last four games. Tyler Higbee is attempting to come back from a knee injury suffered in 2023, and he will assuredly be on some kind of a pitch count if he is active for Week 15.

Deebo Samuel - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Consider Sitting: Deebo Samuel Sr., WR - San Francisco 49ers

Deebo Samuel might be the most divisive player in fantasy football right now, with two camps forming around him. Consider me in the camp of believing that he is washed this year and does not deserve to be in our lineups. Samuel now has four straight games with 4.5 half-PPR fantasy points or less. He aired his frustrations after Sunday’s game, so maybe the squeaky wheel gets the grease here? But I’m not betting on the production, considering his track record in 2024.

Ricky Pearsall - Fantasy Football Rankings, Draft Sleepers, Waiver Wire Pickups

Consider Sitting: Ricky Pearsall, WR - San Francisco 49ers

Nice story. Good player. I’m certainly rooting for him. But he has one total fantasy point in the last four weeks combined. This passing game revolves around Kittle, Jennings, and the running backs right now.

POPULAR FANTASY TOOLS

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REAL-TIME FANTASY NEWS

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Ready to Rock Monday
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Ruled Out Monday
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Hopes to Jumpstart Season at Texas Children's Houston Open
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Ready for Action Monday
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Reds Place Hunter Greene on 60-Day Injured List
Chris Gotterup

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Looks to Keep Strong Season Going in Title Defense in Houston
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JJ Wetherholt Makes Cardinals Opening Day Roster
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Zack Wheeler

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Makes Mets Opening Day Roster
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Facing Playing-Time Questions Heading into 2026
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Officially Signs New Contract With the Chiefs
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Can Denzel Boston Overcome Speed and Athleticism Concerns at the NFL Level?
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Jadarian Price's Dynasty Stock is Rising as the 2026 Draft Approaches
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Can Chris Bell Make an Immediate Impact in the NFL?
Seiya Suzuki

to Start the Season on the Injured List
Travis Homer

Signs With Steelers as RB Depth
Lerone Murphy

Suffers His First Loss
Dennis Santana

Won't be Pirates' Primary Closer
Movsar Evloev

Edges Out Lerone Murphy
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Notre Dame Ranks No. 1 in Returning Production for 2026
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Michael Aswell

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Woody Marks

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Puka Nacua

Extension for Puka Nacua isn't Expected Soon
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Joshua Dobbs

Patriots Planning to Release Joshua Dobbs
Spencer Strider

to Start the Season on Injured List
Iwo Baraniewski

Delivers 28-Second TKO
Lawson Crouse

Picks Up Three Points in Overtime Win
Jahmyr Gibbs

in Line for a Career Workload
Filip Forsberg

Takes Predators Past Blackhawks
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Becomes Highest-Paid Wide Receiver in NFL History
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Scores 1,000th Career Goal
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Eli Stowers' Athleticism Should Not be Overshadowed
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Exits Early Due to Illness
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Kenyon Sadiq's Low Production at Odds with His Elite Athleticism
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to Miss Four-Game Road Trip
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to Return to Full Practice
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Carnell Tate Part of a Loaded Ohio State Rookie Class
A.J. Greer

Handed a Three-Game Suspension
Jonathan Taylor

Still Headlines Colts Backfield
Troy Terry

Wins it for Anahiem
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Ilya Sorokin

Earns Shutout Over Columbus
Ethen Frank

Sustains Lower-Body Injury Sunday
Grayson Rodriguez

to Open Season on Injured List
Brett Pesce

Questionable to Return This Season
Stefan Noesen

Done for the Season
Yan Kuznetsov

Misses Fourth Consecutive Game Sunday
Connor Zary

Out Sunday
Mike Trout

Returns on Sunday
Anthony Duclair

Misses Sunday's Game
Ryan Pulock

Unavailable Sunday
Nick Lodolo

Exits Early With a Blister
Jeremy Peña

Astros Not Ruling Out Jeremy Pena for Opening Day
Cristopher Sánchez

Phillies Sign Cristopher Sanchez to a Six-Year Extension
Tyler Reddick

the Clear Favorite at Darlington
Kyle Stowers

Placed on Injured List with Hamstring Strain
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Morgan Geekie

Records Three Assists Against Red Wings
Steven Stamkos

Notches Three Points in Win Over Golden Knights
Cole Caufield

Records Career-High Five Points in Saturday's Win
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
Nikita Kucherov

Takes Over Scoring Lead With Four-Point Effort
Tyler Tucker

Out Week-to-Week
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Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
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Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
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Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

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Seiya Suzuki

Won't be Ready for Opening Day
Gleyber Torres

Clear to Return on Monday
Konnor Griffin

Assigned to Minor-League Camp
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Scratched From Lineup on Saturday With Lower-Back Tightness
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Movsar Evloev

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Looks To Extend His Win Streak
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In Dire Need Of Victory
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Withdraws From Valspar Championship
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