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Apr 18, 2026, 12:04 AM ET

Houston Astros outfielder Joey Loperfido (quadriceps) left Friday's game early against the St. Louis Cardinals at Daikin Park due to right-quad tightness, according to The Athletic's Chandler Rome. Before leaving the eventual 9-4 loss, Loperfido went 0-for-3 at the plate with one strikeout. He was replaced in left field by Brice Matthews. For now, fantasy managers in deeper leagues will want to consider Loperfido as day-to-day while checking on his status for Game 2 of the series on Saturday. The 26-year-old former seventh-rounder in 2021 out of Duke came into Friday's game hitting .273 (15-for-55) with no home runs, six RBI, seven runs scored, and a stolen base in 19 games played and 63 plate appearances. Loperfido is currently rostered in just 2% of Yahoo leagues. If he's forced to miss time moving forward with his quad injury, Matthews would most likely be the biggest beneficiary of playing time in left field in Houston.--Keith Hernandez
Source: The Athletic - Chandler Rome
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