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Coby Mayo - Fantasy Baseball Prospects Waiver Wire Pickups (Week 10)

Coby Mayo - Fantasy Baseball Prospects, Draft Sleepers, MLB Rookies

Coby Mayo is a fantasy baseball waiver wire pickup for Week 10 (2025). Target Coby Mayo as a top prospect free-agent add for fantasy baseball.

BALLER MOVE: Add in 12+ team Leagues

ROSTERED IN: 5% of Leagues

ANALYSIS: The Baltimore Orioles are expected to promote third base prospect Coby Mayo from Triple-A Norfolk. Andy Kostka of The Baltimore Banner reported that Mayo was scratched from Norfolk's starting lineup on Friday evening and is on his way to Baltimore. First baseman Ryan Mountcastle (hamstring) is currently day-to-day with hamstring discomfort and could be in line to hit the injured list with Mayo on his way to the majors.

Mayo made his MLB debut last season and received another brief taste of the majors earlier this season. Through his first 21 MLB contests, the No. 17-ranked prospect in baseball struggled as he held a modest .094/.186/.094 slash line. During this sample, Mayo did not tally an extra-base hit and held a high 28:5 K:BB.

However, at Triple-A, Mayo has been one of the most productive power hitters over the last two seasons. Since 2024, Mayo has held an impressive .267/.349/.526 slash line with 33 doubles, 30 home runs, and a .875 OPS through 134 total games. Over his last five games, Mayo has held a .350 AVG with a .900 OPS.

With Jordan Westburg (hamstring) also sidelined, Mayo could find a role to have consistent playing time during his third stint in the majors. Given his high power upside, he is worth adding in all 12+ team formats.

- Written by Andy Smith

 

Top Prospect Rankings and 2025 Call-Up ETAs

You can also check out RotoBaller's fantasy baseball prospect rankings for 2025. Eric Cross updates the below rankings weekly for the top impact prospects for 2025, and when they may be called up:

Rank Player Pos Team ETA
1 Roman Anthony OF BOS June
2 Matt Shaw 3B CHC Now
3 Bubba Chandler SP PIT June
4 Jacob Misiorowski SP MIL June
5 Jac Caglianone 1B KCR July
6 Marcelo Mayer SS BOS July
7 Coby Mayo 3B BAL July
8 Brady House 3B WAS June
9 Andrew Painter SP PHI June
10 Colby Thomas OF ATH June
11 Chase DeLauter OF CLE June
12 Samuel Basallo C BAL July
13 Deyvison De Los Santos 1B MIA June
14 Otto Kemp 3B PHI June
15 Shay Whitcomb INF HOU July
16 Kyle Teel C CHW July
17 Thomas Saggese INF STL June
18 Rhett Lowder SP CIN June
19 Zac Veen OF COL June
20 Jonathon Long 3B CHC June
21 Carson Whisenhunt SP SFG June
22 Brandon Sproat SP NYM June
23 Emmanuel Rodriguez OF MIN July
24 Justin Crawford OF PHI July
25 Carson Williams SS TBR July

 

Top Prospect Dynasty Rankings

Looking for longer term fantasy baseball prospect rankings? You can also check out RotoBaller's top dynasty prospect rankings from Eric Cross:

Rank Player Position Team Age ETA Prev
1 Roman Anthony OF BOS 21.01 2025 1
2 Leodalis De Vries SS SDP 18.6 2027 18
3 Nick Kurtz 1B ATH 22.18 Debuted 12
4 Jesus Made SS MIL 18.02 2027 16
5 Jordan Lawlar 2B/SS ARI 22.84 Debuted 15
6 Konnor Griffin SS/OF PIT 19.06 2027 27
7 Travis Bazzana 2B CLE 22.72 2025 6
8 Sebastian Walcott SS TEX 19.18 2026 5
9 Max Clark OF DET 20.4 2026 8
10 J.J. Wetherholt SS STL 22.69 2026 11
11 Zyhir Hope OF LAD 20.32 2026 19
12 Walker Jenkins OF MIN 20.24 2026 4
13 Matt Shaw 3B CHC 23.53 Debuted 7
14 Josue De Paula OF LAD 19.98 2026 34
15 Samuel Basallo C/1B BAL 20.76 2025 13
16 Bubba Chandler P PIT 22.67 2025 29
17 Coby Mayo 3B BAL 23.44 Debuted 17
18 EmManuel Rodriguez OF MIN 22.22 2025 10
19 Andrew Painter P PHI 22.1 2025 14
20 Jackson Jobe P DET 22.8 Debuted 9
21 Kevin McGonigle 2B/SS DET 20.75 2026 20
22 Jac Caglianone 1B KCR 22.27 2025 30
23 Dalton Rushing C/1B LAD 24.24 Debuted 23
24 Felnin Celesten SS SEA 19.67 2027 28
25 Chase DeLauter OF CLE 23.61 2025 21
26 Marcelo Mayer SS BOS 22.43 2025 38
27 Chase Burns P CIN 22.33 2026 46
28 Lazaro Montes OF SEA 20.57 2026 39
29 Bryce Eldridge 1B SFG 20.57 2025 24
30 Robert Calaz OF COL 19.48 2027 31
31 Noah Schultz P CHW 21.78 2025 26
32 Cam Smith OF HOU 22.23 Debuted 36
33 Braden Montgomery OF CHW 22.06 2026 37
34 Agustin Ramirez C/1B MIA 23.69 Debuted 45
35 Travis Sykora P WAS 21.05 2026 41
36 Bryce Rainer SS DET 19.87 2027 61
37 Moises Ballesteros C CHC 21.5 Debuted 60
38 Carson Williams SS TBR 21.9 2025 25
39 Jonny Farmelo OF SEA 20.44 2026 43
40 Emil Morales SS LAD 18.65 2027 42
41 Colt Emerson SS SEA 19.82 2026 32
42 Chase Dollander P COL 23.56 Debuted 47
43 Luis Pena 3B/SS MIL 18.62 2027 134
44 Thomas White P MIA 20.63 2026 68
45 Luke Keaschall 2B MIN 22.76 Debuted 48
46 Aidan Smith OF TBR 20.82 2026 40
47 Jett Williams SS/OF NYM 21.54 2025 53
48 Michael Arroyo 2B SEA 20.53 2026 35
49 Jacob Misiorowski P MIL 23.12 2025 76
50 Colby Thomas OF ATH 24.31 2025 52

 

Popular Player Comparison Searches - Who To Pickup?

Below are some popular searches and comparisons from our fantasy baseball Who To Pickup tool for Coby Mayo and others. You can also use the free Who Should I Pickup tool to run your own waiver wire comparisons, up to four players at once:

Zebby Matthews or Logan Henderson
Bubba Chandler or Zebby Matthews
Will Warren or Zebby Matthews
Zebby Matthews or Bubba Chandler
Chase Meidroth or Matt Shaw
Brandon Lowe or Matt Shaw
Jacob Misiorowski or Zebby Matthews
Jackson Jobe or Bubba Chandler
Matt Shaw or Marcelo Mayer
Zebby Matthews or Jacob Misiorowski
Bubba Chandler or Zebby Matthews
Colin Rea or Zebby Matthews
Drake Baldwin or Dalton Rushing
Hayden Birdsong or Bubba Chandler
Hayden Birdsong or Zebby Matthews
Logan Henderson or Zebby Matthews
Chandler Simpson or Jac Caglianone
Jack Leiter or Bubba Chandler
Jasson Dominguez or Jordan Lawlar
Sandy Alcantara or Roman Anthony
Jac Caglianone or Zebby Matthews
Jacob Misiorowski or Bubba Chandler
Logan Henderson or Jacob Misiorowski
Gunnar Hoglund or Zebby Matthews
Josh Lowe or Jordan Lawlar
Nick Kurtz or Bubba Chandler
Ryan Weathers or Bubba Chandler
Bubba Chandler or Chandler Simpson
Clayton Kershaw or Bubba Chandler
David Festa or Zebby Matthews
Drake Baldwin or Dalton Rushing
Gavin Lux or Marcelo Mayer
Gunnar Hoglund or Bubba Chandler
Gunnar Hoglund or Logan Henderson
Jack Leiter or Zebby Matthews
Jack Leiter or Zebby Matthews
Nick Kurtz or Roman Anthony
Reese Olson or Bubba Chandler
Shane Smith or Jac Caglianone
Spencer Steer or Chandler Simpson
Zebby Matthews or Bubba Chandler
Zebby Matthews or Bubba Chandler
Zebby Matthews or Bubba Chandler
Zebby Matthews or Chandler Simpson
Bubba Chandler or Jacob Misiorowski
Bubba Chandler or Roman Anthony
Chandler Simpson or Jordan Lawlar
Colin Rea or Zebby Matthews
Daulton Varsho or Marcelo Mayer
Grant Holmes or Bubba Chandler
Hyeseong Kim or Jordan Lawlar
Jac Caglianone or Chandler Simpson
Jack Leiter or Bubba Chandler
Jack Leiter or Jacob Misiorowski
Josh Lowe or Matt Shaw
Marcelo Mayer or Matt Shaw
Masyn Winn or Jordan Lawlar
TJ Friedl or Roman Anthony
Tony Gonsolin or Bubba Chandler
Trey Sweeney or Marcelo Mayer
Will Benson or Chandler Simpson
Zebby Matthews or Jac Caglianone
Addison Barger or Jac Caglianone
Agustin Ramirez or Marcelo Mayer
Andy Pages or Roman Anthony
Austin Hays or Marcelo Mayer
Ben Rice or Chandler Simpson
Ben Rice or Marcelo Mayer
Bubba Chandler or Jacob Misiorowski
Bubba Chandler or Zebby Matthews
Camilo Doval or Bubba Chandler
Chandler Simpson or Bubba Chandler
Chase Meidroth or Chandler Simpson
Chase Meidroth or Robert Hasselliii
Drake Baldwin or Moises Ballesteros
Gavin Sheets or Marcelo Mayer
Ivan Herrera or Matt Shaw
Ivan Herrera or Zebby Matthews
Jac Caglianone or Matt Shaw
Jac Caglianone or Roman Anthony
Jake Cronenworth or Chandler Simpson
Jake Meyers or Zebby Matthews
Joe Boyle or Bubba Chandler
Jonathan Aranda or Bubba Chandler
Jordan Lawlar or Dalton Rushing
Jordan Lawlar or Dalton Rushing
Josh Lowe or Jac Caglianone
Logan Henderson or Zebby Matthews
Logan Henderson or Zebby Matthews
Masyn Winn or Chandler Simpson
Matt Shaw or Jac Caglianone
Mitchell Parker or Bubba Chandler
Nick Kurtz or Bubba Chandler
Noah Cameron or Bubba Chandler
Porter Hodge or Jordan Lawlar
Roman Anthony or Bubba Chandler
Roman Anthony or Zebby Matthews
Ronny Henriquez or Chandler Simpson
Ryan Weathers or Bubba Chandler
Will Benson or Marcelo Mayer
Will Warren or Zebby Matthews
Zebby Matthews or Bubba Chandler
Zebby Matthews or Bubba Chandler
Zebby Matthews or Bubba Chandler
Zebby Matthews or Jacob Misiorowski
Zebby Matthews or Jacob Misiorowski
Zebby Matthews or Matt Shaw

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