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Should I start Xavier Worthy, Jakobi Meyers, Marvin Harrison Jr. for Week 5? Fantasy football start 'em, sit 'em picks and recommendations for the 2025 NFL season.
Start and sit decisions get tougher once the bye weeks hit. Roster depth is tested when one of your studs is unavailable, and finding a way to make up those points is crucial.
We'll touch on three wide receivers here and assess their viability as fantasy starters in Week 5: Kansas City Chiefs Xaiver Worthy, Las Vegas Raiders Jakobi Meyers, and Arizona Cardinals Marvin Harrison Jr.
All three have upside cases and reasons for excitement in their matchups. So should you start Worthy, Meyers, or Harrison Jr. in Week 5? Let's dive in.
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Should I Start Xavier Worthy for Fantasy Football?
Xavier Worthy (shoulder) made his return in Week 4 after playing only three snaps in the season opener against the Chargers. His presence was immediately felt for the Kansas City offense, catching five of eight targets for 83 yards, plus taking two carries for 38 yards. The Chiefs blew the Ravens out 37-20, their most points scored in a game since Week 3 of the 2023 season.
It was eye-opening to see what the optimized version of the Chiefs offense could look like, and they'll be getting fellow WR Rashee Rice back in a few weeks, also. Worthy compiled 136 air yards and a 52.5% share of the team's total air yards in Week 5, ninth most among receivers on the week.
Xavier Worthy putting Chidobe Awuzie on skates. pic.twitter.com/oZ6nVmxyRx
— Adam Best (@Arrowhead_Adam) September 29, 2025
Worthy was the obvious focal point of the offense against Baltimore. The first play of the game went to him, and then Mahomes found him on 4th down on the same drive for a big-time conversion to extend the drive. The emerging second-year wideout looks like he's picking up where he left off at the end of last regular season and into the playoffs, where he had at least five receptions over his last eight games and at least 100 yards in two of their three playoff games. He looks like a rising star.
He just barely missed on multiple deep touchdowns last season, and if that starts to regress a little bit for Worthy, his ceiling is boundless. Combined with the creative ways that Andy Reid manufactures touches for him, he is a strong start on Monday night in Jacksonvolle, and should be viewed as a low-end WR1.
Should I Start Jakobi Meyers for Fantasy Football?
Jakobi Meyers is one of the steadiest wide receivers in the league and has always been a consistent producer in fantasy. The upside isn't the highest, but he could take on more volume if star tight end Brock Bowers (knee), who has missed consecutive days in practice, is unable to go on Sunday.
Meyers has earned 33 targets on the year, catching 21 of them for 258 yards. He's surprisingly been overshadowed in the WR room by Tre Tucker, who went nuclear in Week 3 against Washington, hauling in eight of nine targets for 145 yards and three touchdowns.
#Raiders WR Jakobi Meyers had 6 receptions on 12 targets (50% comp) for 68 yards. He’s been a focal point of OC Chip Kelly’s offense. Hopefully GM John Spytek can work out an extension with him. Here are all 6 completions. #RaiderNation pic.twitter.com/yzn2yvvbop
— Chris Reed (@ChrisReed_NFL) September 16, 2025
He draws a favorable matchup against a Colts defense that has allowed the third most fantasy points per game to wide receivers (26.6). Meyers operates mostly out of the slot at 61.2% on the year, and that's an area the Colts have been vulnerable. In Week 2, they allowed Troy Franklin to go catch eight of nine targets and a touchdown when he was used mostly in the slot. Meyers should be in line for a good day and is a solid player to start in Week 5.
Should I Start Marvin Harrison Jr. for Fantasy Football?
Marvin Harrison Jr. had his best fantasy game of the season in Week 4, securing six of 10 targets for 66 yards and a touchdown and finishing with 18.6 PPR points. It was the fourth game of his career with at least 10 targets and matched his career high for receptions in a game.
You can tell how relieved Marvin Harrison Jr was after this catch
You rarely see sadness/relief after scoring a touchdown. Clearly meant more than a TD. Good for Marv, needed that pic.twitter.com/U4xyMqIG6o
— Dalton Feely (@dfeely14) September 26, 2025
Harrison is still a distant second on the team behind superstar tight end Trey McBride in targets, yards, and receptions. It is encouraging to see Harrison and QB Kyler Murray connect on some of these contested catches on the boundary, but the stylistic fit between the two is not ideal. That is a common throw that Murray will target Harrison on, and those are naturally lower percentage plays. Plus, Murray frequently delivers him balls that are just uncatchable.
There is essentially zero competition for targets in the Arizona offense outside of McBride. They lean more run-heavy and could take the air out of the ball even more against a 0-4 Titans team that has been miserable. The matchup doesn't profile to be a positive game script for Harrison and the Cardinals' pass catchers, but Harrison can still be fired up as a WR2 in Week 5.
Who Should I Start Tool
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Who Should I Start? Who Should I Sit? Some common Week 5 fantasy football lineup decisions are regarding players like Xavier Worthy, Jakobi Meyers, Marvin Harrison Jr.. But not to worry, we are here to help make these decisions and build winning lineups in Week 5. Set your optimal fantasy football lineups for Week 5 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Week 5 Player Decisions. Today's focus is on specific players - Xavier Worthy, Jakobi Meyers, Marvin Harrison Jr. These are some of the most common searches for fantasy football lineups in Week 5.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed our Who Should I Start? tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, enhanced search results with data to compare, and a slick new interface. We hope you enjoy!
How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 5 Searches. Curious to see some tough lineup decisions for Week 5 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 5 Searches - Start/Sit Player Comparisons
Below are some popular Week 5 searches and comparisons from our 'Who To Start' tool for Xavier Worthy, Jakobi Meyers, Marvin Harrison Jr. compared to others:
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