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Is Kyler Murray out for the season? When is Kyler Murray coming back? The latest Kyler Murray injury update and fantasy football outlook heading into Week 13 of 2025.
Arizona Cardinals quarterback Kyler Murray hasn't played since Week 5 when he suffered a foot sprain against the Tennessee Titans.
Murray had been underwhelming as a passer, but his rushing ability made him a viable second quarterback in superflex leagues.
With the fantasy football playoffs approaching, managers are wondering when Murray will return and whether it's worth stashing him. Let's dive in!
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Is Kyler Murray Out for the 2025 Season?
After missing three weeks, Murray was placed on the injured reserve following the Cardinals' Week 9 win over the Dallas Cowboys. That move fueled questions about Murray's status for the rest of the season and his future in Arizona.
Murray is working to return. "He's in every meeting, and he's engaged. He's rehabbing a boatload of time in there," head coach Jonathan Gannon said this week.
The first game he would be eligible to play would be the Cardinals' Week 14 matchup against the division rival Los Angeles Rams. If they lose this week, they will be eliminated from playoff contention.
There have been conflicting reports about whether Murray will start when he returns. An interview head coach Jeff Gannon did ahead of Week 10 received a lot of attention. Gannon told Arizona Sports 98.7 FM that Murray would be the QB2 if he was active against the Seattle Seahawks.
Some took that to mean Murray had been benched in favor of Jacoby Brissett, who was (and still is) playing well. However, it is also possible that Gannon simply did not want to rush Murray back before he was 100%. As it happened, Murray was put on the IR, so he didn't play anyway.
Jacoby Brissett Keeps Producing as Cardinals' Starter https://t.co/GNNuVmrw82
— RotoBaller NFL (@RotoBallerNFL) November 25, 2025
Regarding the controversy, Gannon said, "Nothing's changed on that," indicating that Murray remained the QB1 on the depth chart.
Kyler Murray 2025 Fantasy Football Outlook
Murray's passing statistics had been underwhelming in the first five games of the season. He averaged just 192.4 yards per game, 6.0 yards per attempt, and 8.7 yards per completion, all of which would be the worst numbers of his career. For multiple years, Murray has been unable to build on the promise he showed early in his career. His best season for yardage and touchdowns was in 2020.
A strong rushing ability adds to Murray's fantasy viability, although it still does not make him a QB1. Murray's rushing production has remained stable since 2021, which is somewhat impressive considering his age (28) and his injury history.
Before he went down, Murray was averaging 34.6 yards per game on the ground, his highest in the past three years, and 6.0 yards per carry. With the Cardinals' offense being weak overall, he had only scored one rushing touchdown.
If he returns in Week 14, he'll face the Los Angeles Rams, one of the tougher defenses in the league. The Rams have made 12 interceptions, and they are allowing the fifth-fewest fantasy points to QBs.
His Week 15 matchup is even worse. The Houston Texans are allowing the third-fewest passing yards per game and the fewest overall fantasy points to QBs. Even his Week 16 matchup against the Atlanta Falcons is not a strong start, as the Falcons are allowing the tenth-fewest points to QBs.
However, Murray gets a great matchup for Week 17, the traditional championship week, as the Cardinals take on one of the worst defenses in the league, the Cincinnati Bengals. The Bengals have allowed the second-most passing touchdowns, the fourth-most passing yards, and third-most fantasy points to QBs.
If you have a strong lineup overall and spots to spare on your bench or your IR, and if you are expecting to make a playoff run, then it would be worth it to stash Murray for when you need him.
Kyler Murray "Working Hard to Get Healthy" https://t.co/nBXaRPLLDj
— RotoBaller NFL (@RotoBallerNFL) November 25, 2025
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Who Should I Start? Who Should I Sit? Some common Week 13 fantasy football lineup decisions are regarding players like Sean Tucker, Emanuel Wilson, Alec Pierce, Wan'Dale Robinson, Colston Loveland. But not to worry, we are here to help make these decisions and build winning lineups in Week 13. Set your optimal fantasy football lineups for Week 13 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
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Popular Week 8 Searches. Curious to see some tough lineup decisions for Week 8 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 13 Searches - Start/Sit Player Comparisons
Below are some popular Week 13 searches and comparisons from our 'Who To Start' tool for Sean Tucker, Emanuel Wilson, Alec Pierce, Wan'Dale Robinson, Colston Loveland compared to others:
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