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DraftKings Daily Fantasy Baseball Picks (4/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 21, 2018. Troy Klauder's MLB DFS analysis and sleepers for building optimal DFS rosters.

We've got another day full of action ready for us on DraftKings, with an early slate starting at 1pm eastern and the featured slate kicking off at 7pm.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

 You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder.

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DraftKings Starting Pitchers

Aaron Nola, PHI (vs. PIT) - $10,600

Aaron Nola has been rolling along this season, posting a 2.22 ERA through his first two starts of the season. Nola comes at a very modest price for the type of talent he has, which makes him my favorite pitcher on the early slate. While Nola hasn't been racking up many strikeouts this season, he had a 26.6% K-rate in 27 starts last year, so there's probably some positive regression on the way. The Phillies lineup has been on fire lately and should provide Nola with a win against Pirates starter Steven Brault.

Zack Godley, ARI (vs. SD) - $8,800

Godley was horrific in his last start against the Dodgers, but you shouldn't judge a pitcher based off of one bad start. Even with his blow-up start, Godley still has just a 3.00 ERA on the season, supported by a 3.24 FIP. He's a great buy-low candidate on Saturday, as many owners will probably be scared off by his last start, and he comes at a pretty cheap price. The Padres are one of the worst lineups in baseball, and Godley has huge strikeout potential against them, as the Pads strike out 27.9% of the time against righties. That's the third-highest mark in all of baseball, so I would be comfortable playing Godley in any type of contest.

 

DraftKings Infielders

C - Yadier Molina, STL (vs. CIN) - $3,500

Molina has been one of the best catchers in the league at the plate this season, with a 123 wRC+ and five homers so far. His opposition, Reds starter Homer Bailey, has a 3.42 ERA this season - but that's not fooling anybody. Bailey has a 4.74 SIERA this year, which gives a more accurate representation of the way he's pitched this season. After all, he had a 6.43 ERA last season! The Cardinals are a great lineup to stack on Saturday, but you can also use Molina as a standalone at catcher.

1B - Yuli Gurriel, HOU (@ CWS) - $4,200

Gurriel is back from the DL and batting fifth in the loaded Astros lineup, a spot where he can rack up runs and RBIs. The Astros are an expensive lineup to stack, but I would try to at least get a few of them aganist Lucas Giolito. Giolito has struggled mightily this season to the tune of a 5.50 ERA with 12 walks and just eight strikeouts. Gurriel is particularly valuable in cash games, where his high floor makes him more attractive.

2B - Jonathan Villar, MIL (vs. MIA) - $3,500

Villar is actually having himself a fantasy relevant season once again, batting .288 with four steals. His home ballpark, Miller Park, is one of the best offensive environments in all of baseball, and he's facing an awful pitcher in Jose Urena on Saturday. Urena has a 5.57 ERA through his first four starts, and Villar is coming in at a great price against him.

3B - Mike Moustakas, KC (@ DET) - $4,000

Moose has been on fire this season, so it's actually pretty crazy that his price has only gone up to $4,000. In his last 15 games, Moustakas is batting .380 with a 1.092 OPS and four homers. Yowza! Facing Mike Fiers is one of the best possible matchups you can ask for when you play Moustakas, as Fiers has a 1.54 HR/9 this year after posting a 1.88 mark in 2017. Prepare for Moose to go deep.

SS - Ketel Marte, ARI (vs. SD) - $3,500

There are lots of garbage pitchers taking the mound on Saturday, many of which I have already highlighted. We've got another one to target in Padres starter Clayton Richard, who has just a 16.5% K-rate with a 10.3% walk-rate. Unsurprisingly, he's rocking a 5.73 ERA as well. I think Marte's high-contact style of play will play well against Richard's lack of strikeout ability. If nothing else, Marte's got a solid power/speed combo and comes in at a cheap price.

 

DraftKings Outfielders

Jay Bryce, NYM (@ ATL) - $3,900

Braves starter Julio Teheran always struggles when he pitches at home, and SunTrust Park in Atlanta is a fantastic park for left-handed power. This combination gives Jay Bruce a fantastic opportunity to bust out of his slump on Saturday. Teheran's already got a 6.43 ERA at home this season after posting a 5.86 in Atlanta last season, and don't forget that Bruce knocked 36 dingers last season. He's a great value at this price.

Bradley Zimmer, CLE (@ BAL) - $3,300

Indians centerfielder Bradley Zimmer is coming in at near punt-level prices on Saturday, and it's not exactly clear why. He's batting .385 in the last 15 days with a 1.005 OPS! Zimmer has a great matchup in Oriole Park, an outstanding hitter's park, and opposing pitcher Chris Tillman might actually be the worst of the worst pitchers on today's slate. Tillman has a hilarious 11.91 ERA with only three strikeouts and 10 walks in three starts. I recommend an Indians stack, and Zimmer is an essential part of that stack.

Mitch Haniger, SEA (@ TEX) - $4,000

Don't be a goofball and avoid Mariners hitters against Bartolo Colon on Saturday. He had a fantastic start against the Astros his last time out, but he's going to have to show us much more than just that in order to take him seriously. For now, he's still a pitcher we want to target, and Haniger is a great mid-range play to consider against him. Haniger has a 131 wRC+ this season and hasn't gotten a ton of buzz despite his success.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Jake Allen

has Excellent Performance in Defeat
Logan Thompson

Nearly Perfect In Victory
Pascal Siakam

Uncertain for Saturday Against Spurs
Stephon Castle

Questionable for Saturday Versus Pacers
Donovan Mitchell

Questionable as Cavaliers Visit New Orleans
Kevin Porter Jr.

Listed as Questionable Against Phoenix
Isaiah Collier

to Miss Second Straight Game
Joel Embiid

Out Saturday Against Utah
Tanner Bibee

to Take the Ball on Opening Day
Logan Webb

to Start on Opening Day for Giants
Christian Wilkins

"Fully Intends" to Play in 2026
Jake Bobo

Jaguars Sign Receiver Jake Bobo to an Offer Sheet
Trent Williams

49ers Decline to Pick Up Trent Williams' $10 Million Option Bonus
Jaxon Smith-Njigba

Seahawks Exercise Jaxon Smith-Njigba's Fifth-Year Option
Cristopher Sánchez

Cristopher Sanchez to Start on Opening Day for Phillies
Chris Sale

Braves Name Chris Sale as Their Opening Day Starter
Kyle Stowers

Leaves Friday's Game With Hamstring Tightness
DJ Chark

Hangs Up his Cleats
Naz Reid

Ruled Out Friday Against Portland
Jasson Domínguez

Jasson Dominguez Optioned to Triple-A
GG Jackson II

Out Friday Against Boston
Austin Reaves

Added to Injury Report Saturday
Kawhi Leonard

Questionable Against Dallas
Trae Young

Still Sidelined Saturday
Terance Mann

is Unavailable on Friday
Tyler Toffoli

Won't Play Saturday
Andrew Wiggins

Remains Out Saturday
Marcus Sasser

to Sit Out on Friday
Cedric Coward

a Late Scratch Friday
Joel Armia

Ready to Return From Back Injury
Quinten Post

is Ruled Out for Friday's Game
Joel Eriksson Ek

Kirill Kaprizov, Joel Eriksson Ek to Remain Out Saturday
Karl-Anthony Towns

Set to Suit Up Against Brooklyn
Ziaire Williams

to Play on Friday
Ross Colton

Still Out Friday
Ben Saraf

is Available on Friday
Yan Kuznetsov

Remains Sidelined Friday
Ivica Zubac

to Miss Rest of the Season
Shayne Gostisbehere

Misses Seventh Straight Contest
Jacob Misiorowski

Named Opening Day Starter
Morgan Rielly

Cleared to Play Friday
Mike Trout

X-Rays Come Back Negative on Mike Trout's Hand
Ja'Tavion Sanders

Panthers Expect Ja'Tavion Sanders to be Ready for Offseason Program
Dylan Crews

Optioned to Triple-A Rochester
Quinshon Judkins

Does Quinshon Judkins Have RB1 Upside in Dynasty Formats?
Jayden Reed

Is Jayden Reed a Buy-Low Candidate After Injury-Marred 2025 Campaign?
Lerone Murphy

Set For UFC London Main Event
Chris Olave

Rehabs his Dynasty Value With Resurgent 2025 Performance
Movsar Evloev

Looks To Remain Unbeaten
Tyrone Tracy Jr.

Facing Uphill Battle for Playing Time in New York
Michael Aswell

Jr. An Underdog At UFC London
Luke Riley

Set For UFC London Co-Main Event
Chimere Dike

Could See a Diminished Role in 2026
Joe Ryan

Named Opening Day Starter for Twins
Chase Brown

Profiles as a High-End Dynasty Running Back Heading into 2026
Sam Patterson

Looks To Extend His Win Streak
Michael Page

Set For Welterweight Bout
Austen Lane

In Dire Need Of Victory
Iwo Baraniewski

A Favorite At UFC London
C.J. Stroud

Will C.J. Stroud Ever Rediscover his Rookie-Season Magic?
Bijan Robinson

Finally Has the Falcons' Backfield All to Himself
Najee Harris

Remains on the Open Market
George Kittle

Injury Complicates Price Tag
Jameson Williams

Flashes WR1 Upside Ahead of 2026
Parker Washington

a Solidified Fantasy Option Despite Crowded Offense?
Nico Collins

Has Yet to Reach His Full Potential
Collin Murray-Boyles

Unlikely to Play Friday
Sergei Bobrovsky

Shuts Out Oilers with 21 Saves
Trent Frederic

Exits Early Against Panthers
Mason Appleton

Hurt Thursday Night
Tyler Toffoli

Suffers Lower-Body Injury in Thursday's Loss
Victor Hedman

Makes Early Exit Due to Illness
Juuse Saros

Dealing with Upper-Body Injury
Rome Odunze

Steps Into a Larger Role for 2026
Baker Mayfield

Loses Top Receiver After Subpar Season
Spencer Knight

Shuts Down the Wild on Thursday
Adam Fantilli

Scores Two Goals in Victory
Francisco Alvarez

Pulled Early Thursday With Back Tightness
Auston Matthews

Ruled Out for 12 Weeks
Yaroslav Askarov

Still Out Thursday
Luis Severino

to Start for A's on Opening Day
Kirill Kaprizov

Won't Play Against Blackhawks
Alex Tuch

Expected to Return Thursday
Logan Gilbert

Named Mariners Opening Day Starter
José Ramírez

Jose Ramirez Back in Cactus League Lineup on Thursday
Hayden Birdsong

to Have Tommy John Surgery, Miss Entire 2026 Season
Zack Wheeler

to Pitch in Minor-League Game on Monday
Paul Skenes

Pirates Officially Name Paul Skenes Their Opening Day Starter
Jurickson Profar

Officially Suspended for Entire 2026 Season
Carson Williams

"Likely" to Be Rays Opening Day Starting Shortstop
Trey Yesavage

Will Open 2026 on the Injured List Due to Shoulder Impingement
Max Fried

to Start on Opening Day for Yankees
Akshay Bhatia

Withdraws From Valspar Championship
CFB

Alberto Mendoza Drawing Positive Reviews at Georgia Tech
CFB

Anthony Colandrea Impressing in Nebraska's Spring Practices
J.J. Spaun

Offers Upside Despite Poor Course History at Innisbrook
Aaron Rai

Looks to Bounce Back at Valspar Championship
Johnny Keefer

Brings Ball-Striking Upside to Valspar Championship
Billy Horschel

a Volatile Play at Valspar Championship
Ben Griffin

Looks to Rebound at the Valspar Championship
Corey Conners

Brings Elite Ball-Striking to Valspar Championship
Xander Schauffele

Trending In The Right Direction For Valspar Championship
Sahith Theegala

Has Shot to Challenge at Valspar Championship
Mackenzie Hughes

Looking to Bounce Back at Valspar Championship
Nicolai Hojgaard

Finding Rhythm For Valspar Championship
Matt Fitzpatrick

Continues Hot Start to 2026 Heading to Valspar Championship
Pierceson Coody

Heads to Valspar Championship Following Two Missed Cuts
Wyndham Clark

Searching for Momentum at Valspar Championship
Justin Thomas

Is Justin Thomas Back Ahead of This Week's Valspar Championship?
Jordan Spieth

to Bounce Back at Favored Valspar Championship?
Brooks Koepka

is Starting to Find His Groove Again Ahead of Valspar Championship
Viktor Hovland

is One of The Best DFS Plays at Innesbrook
Rasmus Hojgaard

to Get Back on Track at Valspar Championship
Tony Finau

is Again a Scary Option at Valspar Championship
Blades Brown

Continues PGA Tour Run at Valspar Championship
Josh Emmett

Suffers First-Round TKO Loss
Kevin Vallejos

Scores First-Round TKO
Amanda Lemos

Drops Back-To-Back Fights
Gillian Robertson

Extends Her Win Streak
Andre Fili

Drops Decision on Saturday
Denny Hamlin

Dominates and Gets His Third Career Las Vegas Win
Chase Elliott

Earns Runner-Up Finish at Las Vegas
William Byron

Wins A Stage and Finishes Third at Las Vegas
Christopher Bell

Finishes Fourth at Las Vegas After Strong Run
Kyle Larson

Fades to Seventh Despite Leading Laps Early at Las Vegas
Andre Fili

Jose Delgado Edges Andre Fili in Split-Decision Win
Oumar Sy

Suffers First-Round Submission Loss
Ion Cutelaba

Returns To The Win Column
CFB

CJ Carr Enters Sophomore Season as Heisman Favorite
CFB

Aaron Philo Not a Lock to be Florida's Starting QB?
CFB

George MacIntyre the Favorite to Win Tennessee Quarterback Battle?
CFB

Keelon Russell, Austin Mack Battling for Alabama QB1 Duties
Christopher Bell

Looking for Redemption, Wins Pole at Las Vegas
Denny Hamlin

Should Contend for Another Vegas Win
Chase Briscoe

Qualifies 18th Despite Toyota Dominating at Las Vegas
Chase Elliott

May Fly Under the Radar at Las Vegas
NASCAR

Ross Chastian Has Been As Solid As They Come at Las Vegas
Ty Gibbs

Could Ty Gibbs Finally Break Through With a Win at Las Vegas?
Brad Keselowski

a Solid DFS Pick at Las Vegas
Kyle Larson

Should Kyle Larson be Considered A Favorite for Las Vegas?
William Byron

Could Compete for a Top-Five Finish at Las Vegas
Ryan Blaney

Is Ryan Blaney Worth Rostering in Tournament DFS Lineups for Las Vegas?
Tyler Reddick

Could Continue his Top-10 Streak at Las Vegas
Joey Logano

Should DFS Managers Underestimate Joey Logano for Las Vegas?
Chris Buescher

Is Chris Buescher Worth Rostering For Las Vegas DFS Lineups?
NASCAR

Bubba Wallace is A Risky DFS Option Who Could Pay Off at Las Vegas
Josh Berry

Has Plenty of Upside for Las Vegas DFS Lineups
Ryan Preece

Scores his First Las Vegas Top-10 Starting Spot in Qualifying
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF