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Week 6 Running Back Rankings & Matchups Analysis

Below you will find our Week 6 running back rankings, to help determine your RB starts/sits for this week, brought to you by Bill Dubiel (@Roto_Dubs), Nick Mariano (@NMariano53) and Ben Ruppert (@Ben_Ruppert_21).

Featured writer Ben Ruppert also highlights some RB rankings and matchups analysis for Week 6, and draws some matchup conclusions. He tells you who he likes, who he doesn't, and most importantly who he thinks you should be starting in Week 6. You can also check out RotoBaller's overall player rankings here.

Editor's Note: Be sure to check out FantasyAces DFS contests for Week 4. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

Week 6 Running Backs - Rankings & Matchups Analysis

Ezekiel Elliott will have a difficult time this week against the top ranked run defense in the league, the Green Bay Packers. Over his past three games, Elliott has averaged 23 rushes for 137 yards and a TD per game. He has really begun to take advantage of his dominant offensive line, which most weeks will do him extremely well. However, he has yet to face a defense anywhere near this difficult. The past three teams he has faced have averaged 4.4 YPC allowed, compared to the Packers 2.2 YPC. He certainly won’t keep up his 100 yard streak this week, but he will likely score a TD to keep his fantasy impact high.

I thought last week would be the week Lamar Miller finally punched one in, but that prediction ended up being a liiiiiittle too bold. It was easily the worst week Miller has had this season against a defense that could stop a train with a napkin right now. This week he faced a much softer run defense in with the Indianapolis Colts. They have allowed the third most fantasy points to RBs this season, while allowing nearly a TD per game. If there will be a game Miller breaks out, it’ll be this one. This is easily the softest run defense he has faced this season.

If you look past the Bills ugly defensive performance in Week 2, you will see they have been one of the top defenses in the league this season. Carlos Hyde and the 49ers head to Buffalo this week, with Colin Kaepernick at QB. Kaep should help open up some holes with his legs, but Hyde will still have a tough time running through this defensive line with Marcell Dareus now back in the fold. Hyde has ran through tough defenses before, as evidenced by his Week 3 performance against Seattle (21 rushes for 103 yards and two scores). Hyde still has tons of potential, but keep expectations in check against this defense.

On the flip side, if there is a RB out there who will unseat Le’Veon Bell or David Johnson this week, it will be LeSean McCoy. The 49ers defensive weaknesses play into what the Bills do well offensively, mainly running the ball. Shady is having an excellent year so far, averaging 5.3 YPC and 21 touches per game on the ground and through the air. He already topped his TD total from last season, and is fresh off of his best game of the season against the LA Rams. The 49ers have allowed the fifth most fantasy points to opposing RBs, while allowing the most rushing YPG in the league at 133.4 yards. Shady is going to dominate this week.

Fresh off of their bye week, the Chiefs are set to take the training wheels off of RB Jamaal Charles against the Oakland Raiders. Oakland is among the bottom 10 teams in the league in stopping the running game, and is fresh off of allowing Melvin Gordon to rush for 4.3 YPC, while catching a receiving TD. Last time Charles played Oakland he was all over the field, rushing for 80 yards on 19 carries while catching four passes for 42 yards and a score. The only thing keeping Charles from being higher up on this list is we won’t know the volume of touches he will receive this week. If he gets a full work load, watch out.

Devonta Freeman and Tevin Coleman have been an extremely effective two-headed monster for the Falcons this season, so much so that if they were both started by fantasy owners each week you would be very happy. However, this week they face a Seattle defense that will be different than any run defense they have faced this season. Seattle has only allowed 66.5 rushing YPG from opposing RBs, but have also given up 47.8 YPG through the air. Freeman has dominated the ground game, and both backs have caught a similar number of passes. Coleman though has done much more damage in the receiving game this season, out-gaining Freeman 313-to-117 with only three more catches.  With running holes hard to come by and Richard Sherman shadowing Julio Jones, expect a lot of receptions by these backs. I would not be surprised to see Coleman outscore Freeman in fantasy this week.

Jonathan Stewart will make his return from injury this week, and could not have a better matchup. This week the Panthers head to New Orleans to face the Saints, who have allowed the most points to opposing RBs this season. Stewart is fully recovered from the hamstring injury he suffered in Week 2, and will immediately reclaim his role as the top RB over Fozzy Whittaker and Cameron Artis-Payne.  Cam Newton will also return this week after sustaining a concussion against the Falcons in Week 4. With their fully bevy of weapons back, Stewart will be ready to feast on the ground and through the air against this Swiss-cheese defense. As the 38th RB on our list, Stewart is ranked criminally low for the upside he brings this week.

 

Week 6 Fantasy Football Rankings - Running Backs

Rank Player Name Pos
3 Le'Veon Bell RB
4 David Johnson RB
7 DeMarco Murray RB
10 LeSean McCoy RB
13 Ezekiel Elliott RB
17 Lamar Miller RB
18 Todd Gurley RB
23 Theo Riddick RB
27 Jordan Howard RB
28 Mark Ingram RB
31 C.J. Anderson RB
32 Carlos Hyde RB
37 Devonta Freeman RB
39 Melvin Gordon RB
40 Christine Michael RB
50 Eddie Lacy RB
53 Matt Forte RB
55 Ryan Mathews RB
56 Jamaal Charles RB
57 Frank Gore RB
59 Giovani Bernard RB
61 Tevin Coleman RB
62 James White RB
68 Isaiah Crowell RB
73 Terrance West RB
74 LeGarrette Blount RB
78 Duke Johnson RB
79 Arian Foster RB
81 T.J. Yeldon RB
82 Spencer Ware RB
84 Matt Jones RB
86 Darren Sproles RB
87 Bilal Powell RB
100 DeAndre Washington RB
102 Jeremy Hill RB
108 Chris Ivory RB
111 Chris Thompson RB
112 Jonathan Stewart RB
114 Devontae Booker RB
115 Fozzy Whittaker RB
119 Cameron Artis-Payne RB
120 Latavius Murray RB
121 Rashad Jennings RB
122 Jalen Richard RB
126 Jay Ajayi RB
127 Bobby Rainey RB
135 Derrick Henry RB
137 C.J. Spiller RB
143 James Starks RB
148 Kenneth Dixon RB
156 DeAngelo Williams RB
157 Mike Gillislee RB
161 Orleans Darkwa RB
165 Wendell Smallwood RB
168 Jamize Olawale RB
170 Damien Williams RB
175 Javorius Allen RB
177 Alfred Morris RB
180 Jeremy Langford RB
183 Zach Zenner RB
186 Josh Ferguson RB
189 Dwayne Washington RB
195 Dexter McCluster RB
197 Travaris Cadet RB

Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.




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REAL-TIME FANTASY NEWS

Francisco Alvarez

Needs Thumb Surgery, May Play Through Injury
Willy Adames

Out With Side Soreness on Tuesday
A.J. Brown

on Track to Play in Week 1
Jacob deGrom

Being Skipped in Rotation Due to Shoulder Fatigue
Adley Rutschman

Scratched on Tuesday With Abdominal Discomfort
CBJ

Brendan Smith Joins Blue Jackets on Tryout Deal
STL

Milan Lucic Joins Blues for Tryout
DET

Red Wings Pick Up Travis Hamonic
Austin Riley

Doesn't Appear Ready to Return Any Time Soon
Aaron Judge

Unikely to Throw Normally Again This Year
Jalen McMillan

Could be Out Through Week 9 Bye
Indiana Pacers

Pacers Coach Rick Carlisle Agrees to a Multiyear Contract Extension on Tuesday
Washington Wizards

John Wall Retires After 11 NBA Seasons
Daniel Jones

Named as Colts Starting Quarterback
Jalen McMillan

Will Not Be Ready for Season Opener
Collin Sexton

Hornets Have High Hopes for Collin Sexton
Rui Hachimura

Likely to Start Season Without Contract Extension
Jaime Jaquez Jr.

Hopes to Bounce Back in 2025-26
Stephen Curry

Ready to Go for New Season
Orlando Magic

Lester Quinones Agrees to Deal With Magic
Luka Dončić

Luka Doncic Cleared to Play on Tuesday Night
Vladimir Guerrero Jr.

Pulled With Hamstring Tightness
MLB

Game 2 of Brewers-Cubs on Monday Postponed
Bryce Miller

to be Activated on Tuesday
Kyle Tucker

to Get Multiple Days Off
Shane Bieber

to Make Season Debut on Friday
Joe Mixon

Could Start Season on NFI List
Zack Wheeler

has Surgery to Remove Blood Clot
De'Von Achane

Unlikely to Practice This Week
Justin Jefferson

Returning to Practice
Chris Godwin

Bucs Chris Godwin Likely to Start Season on PUP List
Joe Flacco

Browns Name Joe Flacco as Their Week 1 Starter
Jalen McDaniels

Inks Deal With New Orleans
N'Faly Dante

Signs Deal With Hawks
Matthew Stafford

Practicing on Monday
Dru Smith

Agrees to Deal With Heat
Austin Dillon

Scores an Upset Victory at Richmond
William Byron

Clinches the Regular Season Championship Title at Richmond
Denny Hamlin

Pit-Road Struggles Impede Denny Hamlin's Chances of a Top Finish at Richmond
Joey Logano

Earns A Fourth-Place Finish at Richmond
Kyle Larson

Rallies to A Top-10 Finish at Richmond
Malik Nabers

Dealing With Back Injury
Khamzat Chimaev

Is The New UFC Middleweight Champion
Dricus Du Plessis

Gets Dominated At UFC 319
Aaron Pico

Suffers Knockout Loss In His UFC Debut
Lerone Murphy

Scores Stunning First-Round Knockout
Leodalis De Vries

Earns Promotion to Double-A
Nathaniel Lowe

Finalizing Deal with Boston
Geoff Neal

Suffers First-Round Knockout Loss
Ketel Marte

Arizona Could Trade Ketel Marte in the Offseason
Carlos Prates

Gets Back In The Win Column
Michael Page

Dominates At UFC 319
Jared Cannonier

Gets Outclassed
Tim Elliott

Gets Submission Win
Kai Asakura

Still Winless In The UFC
Austin Cindric

has Arguably his Best Run of the Season at Richmond
Ryan Blaney

Contends for First Richmond Win but Comes Up Short
Alex Bowman

Finishes Second but Loses Ground in Playoffs
NASCAR

Bubba Wallace Sets Personal Laps-Led Record at Richmond
Chris Buescher

Falls Out of Playoffs After Miserable Richmond Run
Coby White

Bulls Not Interested in Trading Coby White
Dereck Lively II

Expected to be Ready for Camp
Brian Robinson Jr.

Commanders "Shopping" Brian Robinson Jr.
John Metchie III

Texans Trade John Metchie III to Eagles
Victor Scott II

Placed on 10-Day Injured List
Trey Hendrickson

Bengals Listening to Trade Offers for Trey Hendrickson
Marcelo Mayer

to Have Season-Ending Wrist Surgery
Samuel Basallo

Called Up From Triple-A Norfolk
J.K. Dobbins

Expected to Win Starting RB Job?
Quentin Johnston

Suffers Concussion in Preseason Loss
Jaxson Dart

Plays Well on Saturday Night
Marcus Semien

Avoids Serious Injury
Kyle Stowers

Heads to Injured List With Left-Side Strain
Zack Wheeler

Placed on Injured List With Blood Clot in Shoulder
Terry McLaurin

Commanders Optimistic Terry McLaurin Deal Can Get Done Soon
De'Von Achane

De’Von Achane Dealing With Lower-Body Injury
Luka Dončić

Luka Doncic Likely Avoids Serious Injury
Denny Hamlin

the Heavy Favorite to Win at Richmond
Christopher Bell

Has Been Great at Richmond
Tyrese Haliburton

No Longer Using a Scooter, Crutches
Ryan Blaney

Can Ryan Blaney Finally Break Through at Richmond?
Joey Logano

Will Start Last at Richmond After Practice Trouble
Chase Elliott

Lack of Top-Line Speed Hurts his DFS Potential
Kyle Larson

Recent String of Crashes Make Him a Big Risk at Richmond
William Byron

Probably Slightly Too Inconsistent at Richmond to Start for DFS
Ryan Preece

on Pole at Richmond as Playoff Deadline Looms Closer
Brad Keselowski

Probably the Best RFK Racing DFS Option at Richmond
Chase Briscoe

Still Figuring Out Richmond
Chris Buescher

a Solid Choice for DFS Play, but Teammates Look Faster
Terry McLaurin

Commanders Activate Terry McLaurin From PUP List
Rashee Rice

NFL Could Reach Settlement Before Hearing
Haywood Highsmith

Dealt to Brooklyn on Friday
Amir Coffey

Signs One-Year Deal With Bucks
Khamzat Chimaev

A Favorite At UFC 319
Dricus Du Plessis

Set For His Third Title Defense
Aaron Pico

Set For UFC Debut
Lerone Murphy

Looks To Remain Undefeated
Geoff Neal

Looks For His Second Win In A Row
Michael Page

Set For His Second Middleweight Bout
Jared Cannonier

Looks To Win Back-To-Back Fights
Kai Asakura

Looks For His First UFC Win
Tim Elliott

Set To Open Up UFC 309 Main Card
CBJ

Mikael Pyyhtia Re-Signs With Blue Jackets for One Year
UTA

Caleb Desnoyers Expected to Miss 12 Weeks After Wrist Procedure
Tyson Foerster

on Track to Be Healthy for Season Opener
NHL

Olivier Rodrigue Signs KHL Deal
NHL

Emil Bemstrom to Join Swiss Team
Payton Pritchard

Reportedly Moving Into Starting Lineup
Kevin Durant

Rockets Not Interested in Keeping Kevin Durant with Max Extension
NBA

Isaiah Mobley Joins Turkish Team
NBA

Cole Swider Links Up with EuroLeague Powerhouse

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP