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Must-Start Defenses (D/ST) for Week 8 Fantasy Football (2025)

Matt's must-start fantasy football waiver wire defenses (D/ST) to stream and start for Week 8 of the 2025 season. His fantasy defense start 'em, sit 'em picks.

Week 8 has many fantasy managers in desperation mode, as the NFL schedule features SIX teams on byes in Week 8! Trying to navigate Bye-mageddon? You've come to the right place! RotoBaller analyst Matt Donnelly drops his fantasy football must-start defenses (D/ST) for Week 8 of the 2025 season.

These defenses can impact your matchups in what will be a tough Week 8! We are here to help with your Week 8 D/ST streamers, to give you the tools needed to set those winning lineups and dominate your matchups.

Be sure to tune into RotoBaller Radio on SiriusXM (channel Sirius 210, XM 87) - every weekday morning at 6:00 AM ET. You can also find new weekly shows on YouTubeSpreaker, SpotifyiTunes and on the site under RotoBaller Radio podcasts. Win more in 2025 with RotoBaller!

Be sure to check all of our fantasy football rankings for 2025:

 

2025 Fantasy Football: Week 8 Defenses To Start (D/ST)

Matt Donnelly drops his top Defenses for Week 8 of the 2025 fantasy football season:

Thanks for listening to today's episode! Be sure to tune in throughout the week, and to also follow RotoBaller on Twitter, YouTube, Spotify and iTunes for the latest fantasy news and analysis.

 

Week 8 Fantasy Football Defense Outlooks

Tampa Bay Buccaneers at NO

The Buccaneers will come in as a top-5 play in Week 8 against the New Orleans Saints. The Saints rank 29th in points scored per game, and the offensive line ranks 31st in pass block win rate. As a result, Tampa Bay should be all over New Orleans' offense in this game.

The Buccaneers rank top-6 in both pressure rate and pass rush win rate to begin the season and had an incredible defensive performance two weeks ago against the San Francisco 49ers. In that game, Tampa Bay tallied a season-high six sacks and forced two interceptions. That's enough to start them in Week 8 against a Saints offense that let up a season-high four sacks in Week 7.

Buffalo Bills D/ST at CAR

With Bryce Young (ankle) expected to miss this game, Andy Dalton appears in line to start for the Panthers in Week 8. While Young not starting does hurt Buffalo's defense a little bit, this unit is still a top-5 play this weekend.

In Dalton's five starts with the Panthers last year, opposing defenses averaged eight fantasy points per game. That included two defenses scoring over 15 fantasy points. So, the Bills' D/ST has a ton of potential in this game. Buffalo has totaled multiple sacks in five of its six games this season, and currently ranks 12th in pressure rate.

Cincinnati Bengals D/ST vs. NYJ

This game is a matchup between a poor offense (Jets) and a below-average defense (Bengals). Although this is a fantastic matchup for Cincinnati's defense, it's hard to trust them even in a game like this. This defense ranks 31st in points allowed per game (30.6) and has only tallied five sacks since Week 4. As a result, the Bengals' D/ST shouldn't be any higher on this list.

Nonetheless, this unit can be used in some 12-plus team leagues this week. No offensive line has allowed more sacks than the Jets (31) this year, and New York hasn't scored over 22 points in a game since Week 1. If Trey Hendrickson  -- who ranks 12th in pass rush win rate among all edge rushers -- is back for this game, that would tremendously help this defense.

Atlanta Falcons D/ST vs MIA

The Dolphins look lost on offense right now. Tua Tagovailoa has thrown six interceptions in his last two games, and the offensive line has allowed multiple sacks in five of seven contests this season. That makes the Falcons' D/ST a top-3 play in Week 8.

Atlanta ranks in the top 10 in pressure rate through seven weeks, which should help this defense because Tagovailoa isn't the best quarterback when under pressure. Look at what he did last week against a Browns defense that ranks top-3 in pressure rate (100 pass yards and three interceptions). So, the Falcons' defense is a fantastic start this week.

San Francisco 49ers D/ST at HOU

Even without Fred Warner and Nick Bosa, the 49ers played well defensively against the Falcons last week. They totaled multiple sacks for the first time since Week 2 and held the Falcons offense to just 10 offensive points. While the San Francisco defense has had a hard time generating pressure without Bosa, this unit can capitalize on a plus matchup in Week 8.

C.J. Stroud has been sacked multiple times in every game this season, and Houston's offensive line ranks 29th in pass block win rate. The 49ers might not be a very good defense overall, but they have enough of a fantasy floor to start them in some 12-team leagues.

 

Week 8 D/ST Rankings

D/ST Tier D/ST Rank D/ST Name Pos.
1 1 Indianapolis Colts DST
1 2 Buffalo Bills DST
1 3 Atlanta Falcons DST
1 4 New England Patriots DST
2 5 Tampa Bay Buccaneers DST
2 6 Cincinnati Bengals DST
3 7 Kansas City Chiefs DST
3 8 Green Bay Packers DST
3 9 Philadelphia Eagles DST
3 10 Houston Texans DST
4 11 Denver Broncos DST
4 12 Pittsburgh Steelers DST
4 13 Minnesota Vikings DST
4 14 Los Angeles Chargers DST
4 15 San Francisco 49ers DST
5 16 Cleveland Browns DST
5 17 Baltimore Ravens DST
5 18 New York Jets DST
5 19 New York Giants DST
5 20 Washington Commanders DST
5 21 New Orleans Saints DST
5 22 Chicago Bears DST
6 23 Dallas Cowboys DST
6 24 Miami Dolphins DST
6 25 Carolina Panthers DST
6 26 Tennessee Titans DST

 

Who Should I Start Tool

Not sure who to start? Check out the Who Should I Start tool:

Who Should I Start for 8?

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Who Should I Start? Who Should I Sit? Some common Week 8 fantasy football lineup decisions are regarding defenses like the Indianapolis Colts, Buffalo Bills, Atlanta Falcons, Tampa Bay Buccaneers, Cincinnati Bengals, Los Angeles Chargers, San Francisco 49ers. But not to worry, we are here to help make these decisions and build winning lineups in Week 8. Set your optimal fantasy football lineups for Week 8 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.

Week 8 Player Decisions. Today's focus is on specific defenses like the . These are some of the most common searches for fantasy football lineups in Week 8.

Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.

Improvements For Who Should I Start? You may have noticed, our Who Should I Start? tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, enhanced search results with data to compare, and a slick new interface. We hope you enjoy!

How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.

Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.

Popular Week 8 Searches. Curious to see some tough lineup decisions for Week 8 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.

 

Popular Week 8 Searches - Start/Sit Player Comparisons

Below are some popular Week 8 searches and comparisons from our 'Who To Start' tool for the Indianapolis Colts, Buffalo Bills, Atlanta Falcons, Tampa Bay Buccaneers, Cincinnati Bengals, Los Angeles Chargers, San Francisco 49ers compared to others:

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Parker Romo
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Mac Jones
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Jake Elliott
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Savion Williams

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Kelly Olynyk

Not Ready for Spurs Debut Wednesday
Ace Bailey

Questionable for Season Opener
Isaiah Collier

to Be Re-Evaluated in One Week
Brad Marchand

Delivers Two Assists on Special Night
Adrian Kempe

Lifts Kings to Victory Tuesday
Justin Brazeau

Records Three Points Against Canucks
Jack Hughes

Pots Third Career Hat Trick
TOR

Chris Tanev Could Miss Time With Upper-Body Injury
Jack McBain

Evaluated for Upper-Body Injury
Tom Hoge

Sputtering into Bank of Utah Championship
Sahith Theegala

On the Upswing Heading into Utah
Andrew Putnam

Looks to Find Form in Utah
Matt McCarty

Looks to Defend Title in Utah
Ben Kohles

a Strong Value Play at Bank of Utah Championship
Max Homa

Trending Up Entering the Bank of Utah Championship
Nick Dunlap

Searching for Spark at Bank of Utah Championship
Quade Cummins

Struggling to Find Form Ahead of Bank of Utah Championship
Gabe Vincent

Starting on Tuesday Night
Maxx Crosby

Raiders Won't Trade Maxx Crosby
Jimmy Butler III

Officially Good to Go Versus the Lakers
Jonathan Kuminga

Officially Available on Tuesday Night
Anthony Edwards

Uncertain for the Opener
De'Aaron Fox

Sidelined For Spurs Season Opener
Jonathan Marchessault

Remains Absent Against Ducks
Darcy Kuemper

Available Tuesday
Corey Perry

Makes Season Debut Tuesday
Matt Duchene

Misses Tuesday's Action
Kevon Looney

Unavailable For Season Opener Versus Memphis
Alexander Romanov

Unavailable Versus Sharks
Brock Boeser

Remains Out Tuesday
Jared McCann

Out on Tuesday
Daniel Gafford

Not Expected to Play Versus San Antonio
Darius Garland

Unavailable For Wednesday
Kel'el Ware

Questionable for Wednesday Night
OG Anunoby

Likely Available on Wednesday Evening
Mitchell Robinson

Out Of Action For Knicks Season Opener
Karl-Anthony Towns

Questionable for the Opener
Josh Hart

Unavailable For Knicks Season Opener on Wednesday
Jaylen Brown

Questionable for Celtics Season Opener
Tari Eason

Not Signing His Rookie Extension with the Rockets
Jason Day

Making a Spot Start at Bank of Utah Championship
Luke Clanton

Looks to Build on Momentum This Week in Utah
Los Angeles Angels

Kurt Suzuki to be the Angels' Next Manager
Bo Bichette

Plans to be Ready for World Series
Tyrod Taylor

Aaron Glenn "Moving Toward" Naming Tyrod Taylor the Starting QB
Zach Charbonnet

Finds the End Zone Twice on Monday Night
Jaxon Smith-Njigba

Continues Elite Production
Chris Godwin

Bucky Irving May Not Play This Week
Michael Penix Jr.

Expected to Be "Good to Go" for Sunday
Nick Foligno

Back With Blackhawks
Pierre-Luc Dubois

Remains Sidelined Tuesday
Alexander Romanov

a Game-Time Call for Tuesday
Niko Mikkola

Cleared for Tuesday
Matt Duchene

Probable for Tuesday's Game
Adin Hill

Suffers Lower-Body Injury Monday
Nico Collins

Ruled Out Late on Monday Night With Concussion
Nico Collins

Suffers Head Injury on Monday Night
Jahmyr Gibbs

Blows Up For 218 Total Yards, Two Touchdowns in Win
Mike Evans

to Miss Most of the Year With Broken Clavicle
Brandon Woodruff

Expects to Be Ready for Opening Day
Mike Evans

Ruled Out Monday With Concussion, Shoulder Injury
Mike Evans

Making his Return in Primetime Against Detroit
Emeka Egbuka

Officially Active on Monday Night
Patrik Laine

Remains Out Monday
Jared McCann

Out Against Flyers
Michael Penix Jr.

Dealing With Bone Bruise in Foot, Considered Day-to-Day
Jayden Daniels

Avoids Long-Term Injury, Status Unknown for Week 8
Tua Tagovailoa

Dolphins Sticking With Tua Tagovailoa as Their Starting QB
Brock Bowers

Expected Back After the Bye
Reinier de Ridder

Reinier De Ridder Suffers His First UFC Loss
Brendan Allen

Wins Back-To-Back Fights
Kevin Holland

Drops Decision
Mike Malott

Wins Third Fight In A Row
Marlon Vera

Loses Third Consecutive Fight
Aiemann Zahabi

Gets A Razor-Thin Split Decision Win
Jasmine Jasudavicius

Suffers First-Round TKO Loss
Manon Fiorot

Gets Back In The Win Column
Davey Grant

Suffers Submission Loss
Charles Jourdain

Gets First-Round Submission Win
Matt Frevola

Gets Dominated At UFC Vancouver
Matt Frevola

Kyle Nelson Dominates Matt Frevola
George Springer

Returns to Lineup for Game 6 of ALCS
CFB

Colorado State Fires Head Coach Jay Norvell After Four Seasons
CFB

Florida Fires Head Coach Billy Napier After Four Years
Chase Elliott

Can Chase Elliott Deliver Another Clutch Win to Make Championship 4?
William Byron

Seeks First Win at Talladega to Overcome Las Vegas Crash
Chase Briscoe

Likely to Finish Worse Than he Starts
Kyle Larson

Despite No Wins on Drafting Tracks, Kyle Larson is Improving
Tyler Reddick

Despite Winning at Talladega, Tyler Reddick's Drafting Record Is Not So Hot
Ross Chastain

Poor Qualifying Makes him a Strong DFS Option at Talladega
Chris Buescher

Excellent Crash Avoidance Could Reap Dividends at Talladega
Ty Gibbs

If Ty Gibbs' Team Executes a Better Strategy, he Could Win at Talladega
Daniel Suarez

Hopes for Clutch Talladega Win to Remain in the NASCAR Cup Series
Josh Berry

Might Contend at Talladega
Austin Dillon

Doesn't Lead Enough at Talladega to Contend for Wins
Brendan Donovan

Undergoes Sports Hernia Surgery
George Springer

Exits Game 5 Early After HBP on his Knee
Jackson Chourio

Back in Game 4 Lineup Against Dodgers
Iván Herrera

Ivan Herrera Has Bone Spurs Removed From his Elbow
Brendan Allen

Set For UFC Vancouver Main Event
Reinier de Ridder

Reinier De Ridder A Favorite At UFC Vancouver
Mike Malott

Looks For His Third Consecutive Win
Kevin Holland

Set For UFC Vancouver Co-Main Event
Aiemann Zahabi

Looks For His Seventh Consecutive Win
Marlon Vera

Returns At UFC Vancouver
Jasmine Jasudavicius

Looks To Extend Her Win Streak
Manon Fiorot

Looks To Bounce Back
Aoriqileng

Aori Aoriqileng Looks To Rebound
CFB

Curt Cignetti Signs Eight-Year, $11.6 Million Extension With Indiana
Carlos Rodón

Carlos Rodon Unlikely to Be Ready for Opening Day After Elbow Surgery
Anthony Santander

Removed From ALCS Roster With Back Injury
Jackson Chourio

Aggravates Hamstring, Pulled Early in Game 3 of NLCS
Aaron Judge

Will Not Need Elbow Surgery
Anthony Volpe

Won't be Ready for Start of Next Season
Gerrit Cole

Won't be Ready for Opening Day Next Year

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP