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Casey Wilson's top DraftKings and FanDuel MLB DFS picks for today, Tuesday, 5/5/26. His favorite daily fantasy baseball lineup sleepers and value picks for DFS on DraftKings and FanDuel.
We have a fun Tuesday night slate tonight. There are several spots with great hitting conditions, including Coors Field in elevation, Yankee Stadium with the wind blowing out, and Chase Field with the roof open. There are plenty of aces and value on the bump tonight as well, which gives us an edge to fade some higher rostered players and take down a tournament.
If you have not had a chance to check out my model, I will refer to it throughout this article. To get a better sense of where I am at not only on today's slate but every slate, please give it a look. My plays are solely based on numbers, and this model is the brain behind the operation.
This article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel on 5/5/2026, with the slate starting at 7:05 p.m. ET on FanDuel and DraftKings. The lineup picks will showcase elite players, mid-priced options, and value plays. You can also read more DFS advice and lineup picks for other sports here. Monitoring injury news and today's MLB starting lineups is always essential.
Top MLB DFS Pitcher for DraftKings, FanDuel
Gavin Williams, SP - CLE ($9.3K DK/$10.8K FD)
Gavin Williams is the clear-cut number one option for me on tonight's slate. He will toe the rubber against the Royals at Kauffman Stadium, where it will be in the mid-50s at pitch with a 10+ mph wind blowing in from dead center.
Williams has been a true ace this season for the Guardians, posting a 3.24 xFIP, 31.0% K%, 13.2% SwStr%, 1.02 WHIP, and 1.25 HR/9. He has allowed a 37.8% Hard Hit% this season, but I believe that's because he throws so many strikes. Over his last two starts, Williams has a 23.2% K% but a 33.1% xK% in my model. There is positive regression coming with the strikeouts.
11 strikeouts for Gavin Williams through 7 superb innings! pic.twitter.com/RG46FTtb9a
— MLB (@MLB) April 19, 2026
The Royals have been a middle-of-the-road team against RHP in 2026. They have a 22.1% K%, .701 OPS, and a 93 wRC+ against the split this season. My model has Williams projected for a 28.9% K% and 7.05 strikeouts in this matchup. Fire him up as your SP1 in all formats.
Top MLB DFS Stack for DraftKings, FanDuel
St. Louis Cardinals (Model-Projected IRT of 5.2 runs) vs. Brandon Sproat
I am going right back to the well tonight with the red-hot St. Louis Cardinals with a matchup with Brandon Sproat at Busch Stadium. The weather tonight is pitcher-friendly, but it is hard to ignore the Cardinals' matchup and form.
The Cardinals are on fire as of late, posting a .816 OPS and a 127 wRC+ against RHP over the L14 days. Sproat has allowed a 4.44 xFIP, 1.45 WHIP, 2.79 HR/9, and a 46.4% FB% during that span. Recent form suggests the Cardinals are in a premier matchup.
Digging a bit deeper, Sproat has struggled with LHH this season. The Cardinals have four LHH in their lineup who have posted an OPS above .800 against RHP over the L14 days. Not to mention Ivan Herrera and Jordan Walker from the right side, who are tearing the cover off the ball. This stack is cheap, and I want shares of it again tonight.
Favorite Stack: JJ Wetherholt, Alec Burleson, Nolan Gorman, Ivan Herrera, Jordan Walker, Nathan Church, Pedro Pages
Top MLB DFS Hitter for DraftKings, FanDuel
Mike Trout, OF - LAA ($6.0K DK/$4.4K FD)
Mike Trout is my favorite play tonight on the offensive side of things. He will square off against Erick Fedde, who has allowed a .450 SLG, 12.5% Brl%, and a 37.5% Hard Hit% to RHH in 2026. Trout is slashing .250/.425/.533 with a .958 OPS and 8 HRs against RHP this season. He is in good form with a .955 OPS over his last 22 PA and has a good history against Fedde.
