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MLB DFS Picks for 4/14/26: Daily Fantasy Baseball Strategy and Tips For FanDuel, DraftKings

Otto Lopez - Fantasy Baseball Rankings, Draft Sleepers, Waiver Wire Pickups

Casey Wilson's top DraftKings and FanDuel MLB DFS picks for today, Tuesday, 4/14/26. His favorite daily fantasy baseball lineup sleepers and value picks for DFS on DraftKings and FanDuel.

DraftKings and FanDuel are finally aligned with both slates starting at the same time tonight. This is a miracle in its own right. We have some good hitting conditions again on the East Coast with warm weather and the wind blowing out. We saw a ton of home runs yesterday because of this.

I will be referring to my model today in many instances with implied run totals and projected strikeout numbers for pitchers. Make sure you check it out to always keep learning and understanding why I am referring to these plays.

This article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel on 4/14/2026, with the slate starting at 7:05 p.m. ET on DraftKings and FanDuel. The lineup picks will showcase elite players, mid-priced options, and value plays. You can also read more DFS advice and lineup picks for other sports here. Monitoring injury news and today's MLB starting lineups is always essential.

 

Top MLB DFS Pitcher for DraftKings, FanDuel

MacKenzie Gore, SP - TEX ($8.6K DK/$10.5K FD)

MacKenzie Gore looks incredible tonight. He is in one of the best spots I have seen so far this season. He will toe the rubber at Sutter Health Park tonight against the Athletics. This is a great park for hitting, and that is about the only negative I have in this matchup.

Gore is off to a tremendous start with his new team. He has a 2.06 xFIP, 39.7% K%, 12.3% SwStr%, and a 0.86 WHIP. The Athletics have struggled mightily against southpaws this season and are down arguably their best bat against the split in Brent Rooker. In 2026, the Athletics have a 28.5% K%, .555 OPS, and a 55 wRC+ against LHP.

I love this spot for Gore, and I will be playing him in all formats tonight.

 

Top MLB DFS Stack for DraftKings, FanDuel

Houston Astros (Model Projected IRT (Implied Run Total)- 4.8) vs. Michael Lorenzen

I love this game to hit the over tonight, and I really like the idea of a game stack in this spot. The Astros will face Michael Lorenzen at Daikin Park tonight.

Lorenzen has struggled this season with a 4.43 xFIP, 2.14 WHIP, 1.93 HR/9, and a 37.9% Hard Hit%. The Astros are destroying RHP this season. They have a .835 OPS and a 143 wRC+ against the split.

Lorenzen has shown reverse splits his entire career. In 2025, he allowed a .345 wOBA, .484 SLG, and 14 HRs against RHH. The Astros are a very right-handed-heavy lineup, which lines up very well tonight against the splits of Lorenzen.

Favorite Targets: Jose Altuve, Yordan Alvarez, Christian Walker, Cam Smith, Carlos Correa

 

Top MLB DFS Hitter for DraftKings, FanDuel

Otto Lopez, 2B (FD Only)/SS - MIA ($4.3K DK/$3.3K FD)

I never thought that in the year 2026, I would be writing up Otto Lopez as my top play on a slate, but here we are. Lopez is red hot this season against RHP. He is slashing .303/.378/.576 with a .954 OPS and a 24.0% Brl%. Reynaldo Lopez has allowed a .452 SLG, .290 ISO, and a 17.4% Brl% to RHH in 2026. Otto Lopez will be low-rostered and is a fantastic tournament play tonight.

 

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RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF