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Week 16 NFL DFS Prop Picks for TNF - Over/Under Prop Picks on Sleeper.com

It's Week 16 and Dan has his favorite Thursday Night prop bets on Sleeper. Use Dan's picks to win money on Sleeper!

Welcome to our Sleeper NFL DFS prop picks for Week 16 Thursday Night Football: Saints vs. Rams

Last week’s picks went 2-1, bringing us to 7-2 (78%) since taking over this column in Week 13. Let’s start Week 16 off right with three more top props.

Sleeper offers some of the best and easiest-to-win NFL DFS games in the industry. Sleeper DFS works just like regular player prop betting – there are no large-field tournaments to get lost in. You're not playing against other people; you're just playing against the projections. Here are a few of our favorite prop picks for TNF on Sleeper DFS.

Be sure to check all of our fantasy football rankings for 2025:

 

NFL Sleeper DFS Props - Over/Under Picks for Thursday Night Football

Matthew Stafford OVER 21.5 Completions

Stafford has been on a hot streak in recent weeks, totaling 1,060 passing yards, 12 touchdowns, and only one interception over his last four games. During that span, he has averaged 23.8 completions and 36 attempts per game. Leaning on the passing game recently has worked out well for the Rams, who have won four of their last five games and sit at 7-7 with three games to play. 

This week Stafford and the Rams welcome the Saints to town, a middling opponent who sit as the 15th-best matchup for QBs according to PFF’s strength of schedule metric. The Saints have benefited from a weak division this year and currently sit as the 12th-best defense according to DVOA. That said, Stafford has seemingly elevated his play against top defenses this year, finishing with 22+ completions and 250+ passing yards in all three of his matchups against top-five defenses by DVOA (49ers, Browns, and Ravens).

With a healthy complement of offensive weapons this week in a must-win game to keep pace in the wildcard race, look for Stafford to clear his completions total. With multiple touchdowns in four straight, consider riding with the gunslinger for over 1.5 passing touchdowns as well.

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Alvin Kamara OVER 49.5 Rushing Yards

Kamara’s rushing prop is showing value this week. He has hit 50 or more rushing yards in four straight games and 9-of-11 games this season, averaging 14.6 carries and 57.3 rushing yards per game this year for the Saints.

The Rams have the 22nd-ranked defense according to DVOA. They have given up an average of 110.8 rushing yards per game, 18th-most in the league. While LA has been formidable against opposing fantasy running backs this season (31st in PPR fantasy points allowed to the position), they have not faced a Pro Bowl-caliber runner since Week 9 (Aaron Jones, who finished with 73 rushing yards and a score). They gave up 50+ rushing yard performances to eight RBs in their first nine weeks. 

In a must-win game with star WR Chris Olave still nursing an ankle injury, the Saints will be looking to put the ball in the hands of their top playmaker as much as possible. As such, Kamara is a great pick to produce on the ground and through the air this week.

Derek Carr UNDER 1.5 Passing Touchdowns

Carr has had a largely forgettable first season with the Saints, ranking as the QB18 so far while passing for 3,068 yards, 16 touchdowns, and seven interceptions. After scoring five passing touchdowns in his last two games, now is a great time to sell high by fading Carr.

The 11th-year pro has only five multi-touchdown performances this season (36% of games). His per-game marks of 32 attempts and 1.14 touchdowns are career lows, and his 221.3 passing yards per game is his lowest since his rookie season of 2014. 

The Rams have given up one passing touchdown or less in nine of 14 games this year (64%). The list of QBs they have held to this mark this season includes past or current MVP candidates in Joe Burrow, Jalen Hurts, and Brock Purdy. With Carr often subbed out for Taysom Hill in goal-line scenarios, his touchdown likelihood is even lower. Fade Carr this week.

Be sure to check out the rest of our prop betting coverage later this week. Good luck with your picks!



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REAL-TIME FANTASY NEWS

Johnny Furphy

Listed as Probable Against Bucks
Tucker Kraft

Done for the Year With Torn ACL
Tidjane Salaün

Tidjane Salaun Assigned to G-League Affiliate
Denny Hamlin

Overtime Four-Tire Call Costs Denny Hamlin the Championship
Chase Briscoe

Championship Bid Never Really Started After Two Tire Failures
Brad Keselowski

Nearly Steals Phoenix Race
Blake Wesley

Diagnosed with Broken Foot
David Onama

Suffers First-Round TKO Loss
Anthony Edwards

Cleared for Contact in Practice
Steve Garcia

Scores First-Round TKO Win
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Exits Arena Sunday in Walking Boot
Ante Delija

Suffers His First UFC Loss
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Dylan Raiola Suffers Season-Ending Injury
Waldo Cortes-Acosta

Gets Knockout Win
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Jayden Daniels

Suffers Dislocated Elbow on Sunday Night
Jeremiah Wells

Gets Back In The Win Column
Yadier del Valle

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Jayden Daniels

X-Rays Come Back Negative on Jayden Daniels' Left Arm, MRI to Come
Jaelan Phillips

Gets Dealt to Eagles for a Third-Round Pick
Isaac Dulgarian

Cut By UFC Following Submission Loss
Daniel Frunza

Still Winless In The UFC
Charles Radtke

Dominates Daniel Frunza
Allan Nascimento

Gets Submission Win
Philipp Kurashev

Stays Hot on Sunday
Cody Durden

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Lucas Raymond

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Jake Guentzel

Notches Two Points as Lightning Continue Winning Streak
Leo Carlsson

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Matthew Schaefer

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Michael Pittman Jr.

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Jaxon Smith-Njigba

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Tory Horton

Catches Two Touchdowns in Week 9 Win at Washington
Sam Darnold

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Jayden Daniels

Suffers Gruesome Left-Arm Injury on Sunday Night
Kyren Williams

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Davante Adams

Continues Red-Zone Dominance in Week 9 Win
Dalton Kincaid

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Geno Smith

Throws Four Touchdown Passes in Week 9
DJ Moore

Scores Two Touchdowns, Involved in Several Ways Sunday
Kyle Monangai

Capitalizes on Expanded Role in Week 9
Matthew Stafford

Adds Four More Touchdowns in Sunday's Win
Brock Bowers

Snags Three Touchdown Passes in Grand Return
Brian Thomas Jr.

Injures Ankle in Victory Against Las Vegas
Puka Nacua

Injures Ribs Sunday, Could Have Returned
Rico Dowdle

Delivers Another Huge Showing in Lead-Back Role
Kevin Porter Jr.

Suffers a Knee Injury, Out at Least Four Weeks
Quinn Hughes

Returns to Practice Sunday
Roman Josi

Moved to Injured Reserve
Max Scherzer

Doesn't Plan on Retiring
Michael King

Becomes Free Agent After Declining Mutual Option
Ayo Dosunmu

Sidelined for Rematch Versus the Knicks
Cole Smith

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Walker Kessler

to Undergo Further Testing on Injured Shoulder
Ryan Reaves

Placed on Injured Reserve
NYI

Max Shabanov Not Close to Returning
Jusuf Nurkić

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Tyson Foerster

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Won't Play on Sunday Night
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Nick Cousins

Injured on Saturday
Christopher Tanev

Leaves on Stretcher Saturday
Kevon Looney

Questionable Versus OKC
Chase Briscoe

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Joey Logano

Could Play Spoiler in Championship Battle at Phoenix
Tyler Reddick

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Brad Keselowski

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Daniel Suarez

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Kyle Busch

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Chris Buescher

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AJ Allmendinger

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Jakob Poeltl

to Remain Sidelined Sunday
Walker Kessler

Out on Sunday
Mitchell Robinson

Listed as Questionable for Sunday
Dillon Brooks

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Jalen Green

Unavailable Against Spurs
Norman Powell

Questionable to Suit Up Against Lakers
Jeremy Sochan

Remains Absent Sunday
De'Aaron Fox

Still Out Sunday
Connor Brown

Won't Play on Saturday
Dylan Strome

Ready to Return Saturday
Shohei Ohtani

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Alejandro Kirk

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Bo Bichette

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George Springer

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Steve Garcia

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Set For Co-Main Event
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Jeremiah Wells

Looks To Return To The Win Column
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Isaac Dulgarian

Looks To Win Back-To-Back Fights
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RANKINGS

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RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP