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Who Should I Start for Week 6? Fantasy Football outlooks for Derrick Henry, Davante Adams, JK Dobbins, David Montgomery, Cooper Kupp, George Pickens, Deebo Samuel Sr, Isiah Pacheco, Ricky Pearsall, James Cook.
Who Should I Start? Who Should I Sit? Some of the most common Week 6 fantasy football lineup decisions involve players like Derrick Henry, Davante Adams, J.K. Dobbins, David Montgomery, Cooper Kupp, George Pickens, Deebo Samuel Sr., Isiah Pacheco, Ricky Pearsall, James Cook. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 6. Set your optimal fantasy football lineups for Week 6 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Compare up to four players and we'll tell you who to start...
Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 6:
Davante Adams, WR, Los Angeles Rams
Los Angeles Rams wide receiver Davante Adams has continued to produce despite being second in the pecking order on his own team.
The veteran receiver has 357 yards and three touchdowns this year, making him a high-end WR2 for week-by-week fantasy lineups. While Puka Nacua has earned the bulk of the attention in Los Angeles, Adams has made a significant impact, too, and his productivity so far should not be overlooked or taken for granted.
The 32-year-old represents a safe, dependable WR2 or high-end flex option heading into Week 6 against the Baltimore Ravens.
J.K. Dobbins, RB, Denver Broncos
Denver Broncos running back J.K. Dobbins has "been fantastic," according to Broncos head coach Sean Payton. The 26-year-old is in his first year with the team and has gotten off to a fast start to the season, rushing for 402 yards and four touchdowns on 77 carries through five games.
Dobbins does not offer much as a receiver (six total receptions), but he's been the clear lead rusher in a Broncos backfield that also features RJ Harvey and Tyler Badie. Health has always been a question mark for Dobbins, as he had played in just 22 games over his previous three seasons coming into 2025.
If he stays healthy, it does not appear he's in any danger of losing his current role in Denver. Dobbins profiles as a must-start fantasy running back in Week 6 against the New York Jets.
David Montgomery, RB, Detroit Lions
Detroit Lions running back David Montgomery rushed for 65 yards and a touchdown on 18 carries during Sunday's Week 5 win over the Cincinnati Bengals. He also converted his lone target into a six-yard reception.
Furthermore, the veteran running back was involved in a trick play as he threw a three-yard touchdown pass to tight end Sam LaPorta. In the end, Montgomery finished the victory with 71 scrimmage yards and two total touchdowns. He was the team's leading rusher and also posted a season-high in carries.
While we can't necessarily expect Montgomery to replicate this type of performance going forward, he has established himself as a high-end RB3/flex option once again in 2025. He should be started in leagues with at least 10 teams when he takes on the Kansas City Chiefs next week.
Deebo Samuel Sr, WR, Washington Commanders
Washington Commanders wide receiver Deebo Samuel Sr. stayed heavily involved in the team's offense with Terry McLaurin (quadriceps) missing a second straight game on Sunday on the road against the Los Angeles Chargers.
Samuel led the team in targets (11), receptions (eight), and receiving yards (96) while catching his third touchdown of the season in the 27-10 victory in Week 5 in quarterback Jayden Daniels' return from a knee sprain. The 29-year-old has had a nice bounce-back season in 2025 so far in his first year in Washington while being the team's most consistent pass-catcher. Through the first five weeks, Samuel has 346 scrimmage yards and four touchdowns.
As long as he can stay healthy, Samuel should continue to be a must-start in fantasy lineups, even when McLaurin returns from his quad injury. Samuel will have quite a bit of upside in Week 6 on Monday night against the Chicago Bears, especially if McLaurin misses a third game.
Ricky Pearsall, WR, San Francisco 49ers
San Francisco 49ers wide receiver Ricky Pearsall (knee) did not practice on Wednesday and is not expected to play in their Week 6 matchup at Tampa Bay, according to Tracy Sandler of FGSN.
Pearsall is now set to miss his second straight game after suffering a PCL injury in the 49ers' Week 4 loss to the Jaguars. It's unfortunate, as Pearsall had been enjoying a fantastic start to the season, catching 20 of 29 targets for 327 yards.
His absence will again open up more opportunities for Week 5's breakout performer, Kendrick Bourne, as well as another heavy workload for star back Christian McCaffrey.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 6 Player Decisions. Today's focus is on specific players - Derrick Henry, Davante Adams, JK Dobbins, David Montgomery, Cooper Kupp, George Pickens, Deebo Samuel Sr, Isiah Pacheco, Ricky Pearsall, James Cook. These are some of the most common searches for fantasy football lineups in Week 6.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 6 Searches. Curious to see some tough lineup decisions for Week 6 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 6 Searches - Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 6 for Derrick Henry, Davante Adams, JK Dobbins, David Montgomery, Cooper Kupp, George Pickens, Deebo Samuel Sr, Isiah Pacheco, Ricky Pearsall, James Cook:
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