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Oct 25, 2026, 1:54 PM ET

San Francisco 49ers running back Christian McCaffrey (thigh) is questionable to return to a Week 7 game against the Atlanta Falcons with a thigh injury, according to Nick Wagoner of ESPN. Harrison Rich of the San Francisco Chronicle reported that McCaffrey was spotted in the medical tent with a massage gun on his left hamstring/thigh. McCaffrey recorded four rushes for 29 yards (7.3 yards per carry) and a touchdown, along with three receptions for 45 yards (15.0 yards per catch), before exiting the contest. While McCaffrey is out, the 49ers will rely on running back Kaelon Black, who has already recorded a 30-yard touchdown run.--Ryan O'Bleness
Source: Nick Wagoner - ESPN
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Oct 24, 2026, 10:45 PM ET

San Francisco 49ers running back Kaelon Black currently lacks standalone value in his role as the No. 2 ball-carrier behind Christian McCaffrey. However, he is one of the league's highest-upside handcuffs because of how much his value would rise if McCaffrey were to miss any time. McCaffrey had 25 touches last week, including nine receptions. While Black may not quite handle that many touches in this hypothetical jump to the No. 1 spot on the depth chart, he would absolutely be the lead-back option ahead of Jordan James, who hasn't played an offensive snap since Week 2. Black has been much more involved to this point, amassing 45 carries, 170 rushing yards, two catches, and eight receiving yards. Evidently, while Black would take on a lot of McCaffrey's hypothetically vacated rushing attempts, the 25-year-old rookie doesn't have much appeal in the passing game, and so he'd have less value and a lower floor in PPR leagues compared to half-PPR and standard formats.--Andersen Pickard
Source: RotoBaller
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Oct 24, 2026, 9:24 PM ET

San Francisco 49ers wide receiver Christian Kirk (calf) has been activated from the Injured Reserve ahead of the Week 7 matchup against the Atlanta Falcons. Kirk has been sidelined since suffering a calf injury during training camp in late July. He's set to make his season debut this weekend after missing the first six games of the regular season. Kirk could immediately become a top target with Mike Evans (ribs, Achilles) and Deebo Samuel Sr. (hamstring) both ruled out. The veteran wideout might end up becoming the top target in the offense during his first game back in the mix. Fantasy managers in deep leagues looking for a possible flex option should consider adding Kirk.--Andy Webb
Source: Pro Football Reference
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Oct 24, 2026, 4:59 PM ET

San Francisco 49ers wide receiver Christian Kirk (calf) has been activated from Injured Reserve ahead of his team's Week 7 matchup against the Atlanta Falcons. Kirk has yet to play in 2026 after suffering a calf injury in training camp. However, he could profile as San Francisco's WR1 immediately upon his return, as the 49ers will be without top wideouts Mike Evans (Achilles, ribs) and Deebo Samuel Sr. (hamstring) against Atlanta. Across 13 games with the Houston Texans in 2025, Kirk recorded 28 catches for 239 yards and a touchdown on 52 targets. The 49ers will undoubtedly heavily feature tight end George Kittle and running back Christian McCaffrey in their passing game, so fantasy managers should temper expectations for Kirk. Still, the veteran profiles as an intriguing wide receiver streamer in Week 7.--Will Brady
Source: The Athletic - Matt Barrows
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Oct 24, 2026, 3:19 PM ET

San Francisco 49ers wide receiver Brandin Cooks is a speculative addition in 12-team leagues for managers seeking immediate receiver help, but his limited target production makes him a risky Week 7 flex option. He could see his largest workload of the season against the Atlanta Falcons in Week 7, with Mike Evans (ribs, Achilles) and Deebo Samuel Sr. (hamstring) ruled out, and the matchup is favorable, as Atlanta has surrendered the most receptions and fourth-most receiving yards to opposing wide receivers this season. Cooks took over Evans' outside receiver role after the veteran exited Monday's win over the Washington Commanders, playing a season-high 32 offensive snaps (52%), but he caught just one of two targets for 13 yards and has only two receptions for 20 yards and a touchdown across three games. Jordan Watkins played 47 snaps against Washington, while Christian Kirk (calf) is questionable after practicing fully throughout the week and could return.--Bruno Mulé
Source: RotoBaller
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Oct 24, 2026, 10:08 AM ET

Across six games in 2026, San Francisco 49ers rookie running back Kaelon Black has recorded 45 carries for 170 yards and two catches for eight yards on three targets. While Black has seen at least six carries in all but one of the 49ers' games this season, his production upside is capped by the presence of star San Francisco back Christian McCaffrey. In Week 7, the 49ers will take on the Atlanta Falcons. Atlanta has fielded a strong run defense in 2026, ranking sixth in the NFL in both yards per carry allowed (3.6) and total rushing yards allowed (499). Black remains a priority handcuff running back option for fantasy managers to stash in a bench spot. However, with McCaffrey entering the game fully healthy, Black is hard to trust as a starter in Week 7.--Will Brady
Source: RotoBaller
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Oct 24, 2026, 5:49 AM ET

The San Francisco 49ers' Week 7 opponent, the Atlanta Falcons, are giving up the fourth-most fantasy points to opposing D/ST units in 2026. Atlanta's offense has been putting up points after a slow start, averaging 31.5 points per game since Week 3, but they are still prone to allowing sacks and turning the ball over. Atlanta has the seventh-highest sack rate in the NFL, and the 49ers have the fifth-highest pressure rate over the last three weeks, despite missing Nick Bosa (knee, calf), who will be out again on Sunday. The Falcons have thrown just one interception in the last three weeks, but lost three fumbles to their opponent in Week 6. Despite the shootout potential, San Francisco's D/ST is a good floor play based on their ability to get to the quarterback and their opponent's sometimes sloppy ball protection.--Dan Stephens
Source: NFL.com
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Oct 24, 2026, 5:44 AM ET

San Francisco 49ers kicker Eddy Pineiro sank his only field goal attempt in Week 6, but missed an extra point try in the team's win over the Commanders. The miss was Pineiro's third whiff on an extra point this season. Pineiro is now 19-for-22 on extra point attempts and 6-for-9 on field goals. Accuracy woes aside, the 49ers' efficiency on offense has stymied Pineiro's production. Pineiro leads the NFL in extra point attempts, but is near the bottom in field goal attempts. There are only three other active kickers who match Pineiro or rank below him, and two of them were on a bye last week. San Francisco's upcoming meeting with the Atlanta Falcons has the second-highest expected point total on the Week 7 slate. Pineiro looks like a safe floor play who will, at the very least, get a handful of extra points and a field goal try in a high-scoring affair.--Dan Stephens
Source: NFL.com
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Oct 24, 2026, 5:39 AM ET

San Francisco 49ers tight end George Kittle has finished in the top seven at his position in four out of six games, scoring at least 17.0 PPR points in each of those contests. In Week 6, he caught five passes for 65 yards and a touchdown on eight targets. Only Christian McCaffrey got more looks with Deebo Samuel Sr. (hamstring) out and Mike Evans leaving injured just before halftime. Both wide receivers have been ruled out for San Francisco's Week 7 game against the Falcons, positioning Kittle for a high-volume game. Atlanta has given up the seventh-most receptions and ninth-most fantasy points to opposing tight ends. Through six weeks, Kittle leads tight ends in touchdowns with five, has the fourth-most receiving yards, and is the overall TE3 in fantasy. He is projected as a TE1 and should be locked into the starting lineup for Week 7.--Dan Stephens
Source: NFL.com
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Oct 24, 2026, 5:36 AM ET

San Francisco 49ers wide receiver Christian Kirk (calf) has been on injured reserve since the preseason but is expected to be activated for the Week 7 meeting with the Atlanta Falcons. Kirk is tagged as questionable but was a full participant in every practice this week. The veteran's timing is impeccable, as the 49ers have ruled out both Deebo Samuel Sr. (hamstring) and Mike Evans (ribs, Achilles). Kirk will be in contention with Brandin Cooks and Jordan Watkins for targets behind Christian McCaffrey and George Kittle, who led the team last week when Samuel was out and Evans exited early. If Kirk wins his position battle, it could be a lucrative day as the Falcons have allowed the fourth-most PPR points to wide receivers in 2026. His unknown spot in the 49ers' pecking order caps his projection as a WR5, so he is a gamble best taken on in deep leagues.--Dan Stephens
Source: David Lombardi - San Francisco Standard
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Oct 24, 2026, 5:32 AM ET

San Francisco 49ers wide receiver Jordan Watkins saw his snap share jump to 76% in Week 6, double that in each of his previous two games. Deebo Samuel Sr.'s (hamstring) absence and Mike Evans' (ribs, Achilles) early departure paved the way for more time on the field. That didn't translate to increased production (Watkins saw just one target, good for a 22-yard reception), but the substantial increase in playing time outdid that of Brandin Cooks and Jacob Cowing, the latter of whom actually saw his snaps decrease. In Week 7, the 49ers face the Falcons, who have given up the most receptions and seventh-most half-PPR points to wide receivers this year. Watkins will contend with Cooks and, if he is cleared to play, Christian Kirk (calf) for targets behind Christian McCaffrey and George Kittle. As such, he projects as a WR5 who is best left as a deep-league dart throw for Week 7.--Dan Stephens
Source: NFL.com
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Oct 24, 2026, 5:22 AM ET

San Francisco 49ers receiver Brandin Cooks has not been very involved in the offense since joining the team three weeks ago, but stands to take a step forward in Week 7. In Week 6, injuries to Deebo Samuel Sr. (hamstring) and Mike Evans (ribs, Achilles) opened the door for Cooks to be on the field for more than 50% of offensive plays for the first time. Both receivers have been ruled out for Week 7, pushing Cooks up the depth chart and positioning him to soak up some of their target share. Cooks will still have to contend with Jordan Watkins and possibly Christian Kirk (calf) for looks behind George Kittle and Christian McCaffrey, making him a somewhat risky start. There is the potential for a big week, as the Falcons have given up the most receptions, fourth-most receiving yards, and seventh-most half-PPR points to wide receivers. Cooks projects as a WR4 going into Week 7. His matchup elevates his ceiling, making him a worthwhile gamble in deeper leagues.--Dan Stephens
Source: NFL.com
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Oct 24, 2026, 5:12 AM ET

San Francisco 49ers running back Christian McCaffrey had his biggest game of the season in Week 6 against the Commanders. McCaffrey gained 118 scrimmage yards, extended his scoring streak to a fifth game with two touchdown runs, and logged 25 touches - his most in a game all year. McCaffrey led the team with nine catches and 10 targets with Deebo Samuel Sr. (hamstring) out of the lineup and Mike Evans (ribs, Achilles) forced out early due to injury. Both wide receivers will be out for Week 7, which puts McCaffrey in position to act as Brock Purdy's primary target. The Atlanta Falcons are tied for the fourth most receptions allowed to opposing running backs through Week 6. McCaffrey has four top-10 finishes under his belt already in 2026, and is projected for another one in Week 7. He should be locked into starting lineups.--Dan Stephens
Source: NFL.com
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Oct 24, 2026, 4:57 AM ET

San Francisco 49ers quarterback Brock Purdy threw for 264 yards and one touchdown in Week 6, good enough for his fifth top-12 finish in the first six weeks of the season. It was Purdy's highest passing total since Week 3, despite Deebo Samuel Sr. (hamstring) sitting out and Mike Evans (ribs, Achilles) exiting the game early due to injury. Both receivers have been ruled out for Week 7, but Purdy seems to find success in Kyle Shanahan's system whoever he is working with. Christian McCaffrey and George Kittle will likely operate as Purdy's top two targets, and Brandin Cooks or Jordan Watkins are in line for more work, along with Christian Kirk (calf), who is expected to make his season debut on Sunday. The Falcons have allowed the third-most passing yards and 10 passing touchdowns to one interception. Even though he is missing his top wide receivers, Purdy is still a good bet for another QB1 finish in Week 7.--Dan Stephens
Source: NFL.com
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Oct 23, 2026, 9:37 PM ET

San Francisco 49ers wide receiver Christian Kirk (calf) is listed as questionable ahead of the Week 7 matchup against the Atlanta Falcons. The expectation is that Kirk will return from the Injured Reserve this weekend. He has been sidelined all season due to a calf issue. His potential return comes at a good time with the 49ers desperately needing bodies at wide receiver. Both Mike Evans (ribs, Achilles) and Deebo Samuel Sr. (hamstring) have been ruled out. Kirk could be in for a steady workload, assuming he's active this weekend. Fantasy managers will need to check back for another update on his status.--Andy Webb
Source: Josh Dubow
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